Abstract: Phase-Contrast MR imaging methods are widely used
for measurement of blood flow velocity components. Also there are
some other tools such as CT and Ultrasound for velocity map
detection in intravascular studies. These data are used in deriving
flow characteristics. Some clinical applications are investigated
which use pressure distribution in diagnosis of intravascular disorders
such as vascular stenosis. In this paper an approach to the problem of
measurement of intravascular pressure field by using velocity field
obtained from flow images is proposed. The method presented in this
paper uses an algorithm to calculate nonlinear equations of Navier-
Stokes, assuming blood as an incompressible and Newtonian fluid.
Flow images usually suffer the lack of spatial resolution. Our
attempt is to consider the effect of spatial resolution on the pressure
distribution estimated from this method. In order to achieve this aim,
velocity map of a numerical phantom is derived at six different
spatial resolutions. To determine the effects of vascular stenoses on
pressure distribution, a stenotic phantom geometry is considered. A
comparison between the pressure distribution obtained from the
phantom and the pressure resulted from the algorithm is presented. In
this regard we also compared the effects of collocated and staggered
computational grids on the pressure distribution resulted from this
algorithm.
Abstract: Fecal sterol has been proposed as a chemical indicator
of human fecal pollution even when fecal coliform populations have
diminished due to water chlorination or toxic effects of industrial
effluents. This paper describes an improved derivatization procedure
for simultaneous determination of four fecal sterols including
coprostanol, epicholestanol, cholesterol and cholestanol using gas
chromatography-mass spectrometry (GC-MS), via optimization study
on silylation procedures using N-O-bis
(trimethylsilyl)-trifluoroacetamide (BSTFA), and
N-(tert-butyldimethylsilyl)-N-methyltrifluoroacetamide
(MTBSTFA), which lead to the formation of trimethylsilyl (TMS) and
tert-butyldimethylsilyl (TBS) derivatives, respectively. Two
derivatization processes of injection-port derivatization and water bath
derivatization (60 oC, 1h) were inspected and compared. Furthermore,
the methylation procedure at 25 oC for 2h with
trimethylsilydiazomethane (TMSD) for fecal sterols analysis was also
studied. It was found that most of TMS derivatives demonstrated the
highest sensitivities, followed by methylated derivatives. For BSTFA
or MTBSTFA derivatization processes, the simple injection-port
derivatization process could achieve the same efficiency as that in the
tedious water bath derivatization procedure.
Abstract: This article illustrates a model selection management approach for virtual prototypes in interactive simulations. In those numerical simulations, the virtual prototype and its environment are modelled as a multiagent system, where every entity (prototype,human, etc.) is modelled as an agent. In particular, virtual prototyp ingagents that provide mathematical models of mechanical behaviour inform of computational methods are considered. This work argues that selection of an appropriate model in a changing environment,supported by models? characteristics, can be managed by the deter-mination a priori of specific exploitation and performance measures of virtual prototype models. As different models exist to represent a single phenomenon, it is not always possible to select the best one under all possible circumstances of the environment. Instead the most appropriate shall be selecting according to the use case. The proposed approach consists in identifying relevant metrics or indicators for each group of models (e.g. entity models, global model), formulate their qualification, analyse the performance, and apply the qualification criteria. Then, a model can be selected based on the performance prediction obtained from its qualification. The authors hope that this approach will not only help to inform engineers and researchers about another approach for selecting virtual prototype models, but also assist virtual prototype engineers in the systematic or automatic model selection.
Abstract: This paper presents a time control liquids mixing
system in the tanks as an application of fuzzy time control discrete
model. The system is designed for a wide range of industrial
applications. The simulation design of control system has three
inputs: volume, viscosity, and selection of product, along with the
three external control adjustments for the system calibration or to
take over the control of the system autonomously in local or
distributed environment. There are four controlling elements: rotatory
motor, grinding motor, heating and cooling units, and valves
selection, each with time frame limit. The system consists of three
controlled variables measurement through its sensing mechanism for
feed back control. This design also facilitates the liquids mixing
system to grind certain materials in tanks and mix with fluids under
required temperature controlled environment to achieve certain
viscous level. Design of: fuzzifier, inference engine, rule base,
deffuzifiers, and discrete event control system, is discussed. Time
control fuzzy rules are formulated, applied and tested using
MATLAB simulation for the system.
Abstract: The ultimate goal of this article is to develop a robust and accurate numerical method for solving hyperbolic conservation laws in one and two dimensions. A hybrid numerical method, coupling a cheap fourth order total variation diminishing (TVD) scheme [1] for smooth region and a Robust seventh-order weighted non-oscillatory (WENO) scheme [2] near discontinuities, is considered. High order multi-resolution analysis is used to detect the high gradients regions of the numerical solution in order to capture the shocks with the WENO scheme, while the smooth regions are computed with fourth order total variation diminishing (TVD). For time integration, we use the third order TVD Runge-Kutta scheme. The accuracy of the resulting hybrid high order scheme is comparable with these of WENO, but with significant decrease of the CPU cost. Numerical demonstrates that the proposed scheme is comparable to the high order WENO scheme and superior to the fourth order TVD scheme. Our scheme has the added advantage of simplicity and computational efficiency. Numerical tests are presented which show the robustness and effectiveness of the proposed scheme.
Abstract: The study investigated the 2011 TPGA Ever Rich
Championship – North Bay Open spectators- on-the-site spectating
motivations, experiences, and satisfactions. The research was
conducted on a convenience sample of the on-the-spot spectators at the
North Bay Golf and Country Club. A total of 200 questionnaires were
distributed, of which 185 valid questionnaires were collected,
approaching a 92.5% response rate. The data obtained was analyzed
with statistical techniques. First, the data showed significant
differences in motivations, experiences, and satisfactions relative to
demographic variables among the on-the-spot spectators. Second,
spectating motivation, experience, and satisfaction were significantly
related to one another.
Abstract: For this study, this researcher conducted a precision
network adjustment with QOCA, the precision network adjustment
software developed by Jet Propulsion Laboratory, to perform an
integrated network adjustment on the Unified Control Points managed
by the National Geographic Information Institute. Towards this end,
275 Unified Control Points observed in 2008 were selected before a
network adjustment is performed on those 275 Unified Control Points.
The RMSE on the discrepancies of coordinates as compared to the
results of GLOBK was ±6.07mm along the N axis, ±2.68mm along the
E axis and ±6.49mm along the U axis.
Abstract: In order to provide and maintain effective pedagogy for the burgeoning virtual reality community, it is vital to have trained faculty in the institutions of higher education who will teach these courses and be able to make full use of their academic knowledge and expertise. As the number of online courses continues to grow, there is a need for these institutions to establish mentoring programs that will support the novice online instructor. The environment in which this takes place and the factors that ensure its success are critical to the adoption of the new instructional delivery format taught by both seasoned educators and adjunct instructors. Effective one-on-one mentoring promotes a professional, compassionate and collegial faculty who will provide a consistent and rigorous academic program for students online.
Abstract: We demonstrate a 1×4 coarse wavelength
division-multiplexing (CWDM) planar concave grating
multiplexer/demultiplexer and its application in re-configurable
optical add/drop multiplexer (ROADM) system in silicon-on-insulator
substrate. The wavelengths of the demonstrated concave grating
multiplexer align well with the ITU-T standard. We demonstrate a
prototype of ROADM comprising two such concave gratings and four
wide-band thermo-optical MZI switches. Undercut technology which
removes the underneath silicon substrate is adopted in optical switches
in order to minimize the operation power. For all the thermal heaters,
the operation voltage is smaller than 1.5 V, and the switch power is
~2.4 mW. High throughput pseudorandom binary sequence (PRBS)
data transmission with up to 100 Gb/s is demonstrated, showing the
high-performance ROADM functionality.
Abstract: In this paper, a delayed predator–prey system with stage
structure is investigated. Sufficient conditions for the system to have
multiple periodic solutions are obtained when the delay is sufficiently
large by applying Bendixson-s criterion. Further, some numerical
examples are given.
Abstract: The Improved Generalized Diversity Index (IGDI)
has been proposed as a tool that can be used to identify areas that
have high conservation value and measure the ecological condition of
an area. IGDI is based on the species relative abundances. This paper
is concerned with particular attention is given to comparisons
involving the MacArthur model of species abundances. The
properties and performance of various species indices were assessed.
Both IGDI and species richness increased with sampling area
according to a power function. IGDI were also found to be acceptable
ecological indicators of conditions and consistently outperformed
coefficient of conservatism indices.
Abstract: Nature conducts its action in a very private manner. To
reveal these actions classical science has done a great effort. But
classical science can experiment only with the things that can be seen
with eyes. Beyond the scope of classical science quantum science
works very well. It is based on some postulates like qubit,
superposition of two states, entanglement, measurement and
evolution of states that are briefly described in the present paper.
One of the applications of quantum computing i.e.
implementation of a novel quantum evolutionary algorithm(QEA) to
automate the time tabling problem of Dayalbagh Educational Institute
(Deemed University) is also presented in this paper. Making a good
timetable is a scheduling problem. It is NP-hard, multi-constrained,
complex and a combinatorial optimization problem. The solution of
this problem cannot be obtained in polynomial time. The QEA uses
genetic operators on the Q-bit as well as updating operator of
quantum gate which is introduced as a variation operator to converge
toward better solutions.
Abstract: It is well known that Logistic Regression is the gold
standard method for predicting clinical outcome, especially
predicting risk of mortality. In this paper, the Decision Tree method
has been proposed to solve specific problems that commonly use
Logistic Regression as a solution. The Biochemistry and
Haematology Outcome Model (BHOM) dataset obtained from
Portsmouth NHS Hospital from 1 January to 31 December 2001 was
divided into four subsets. One subset of training data was used to
generate a model, and the model obtained was then applied to three
testing datasets. The performance of each model from both methods
was then compared using calibration (the χ2 test or chi-test) and
discrimination (area under ROC curve or c-index). The experiment
presented that both methods have reasonable results in the case of the
c-index. However, in some cases the calibration value (χ2) obtained
quite a high result. After conducting experiments and investigating
the advantages and disadvantages of each method, we can conclude
that Decision Trees can be seen as a worthy alternative to Logistic
Regression in the area of Data Mining.
Abstract: Rapid Prototyping (RP) is a technology that produces models and prototype parts from 3D CAD model data, CT/MRI scan data, and model data created from 3D object digitizing systems. There are several RP process like Stereolithography (SLA), Solid Ground Curing (SGC), Selective Laser Sintering (SLS), Fused Deposition Modeling (FDM), 3D Printing (3DP) among them SLS and FDM RP processes are used to fabricate pattern of custom cranial implant. RP technology is useful in engineering and biomedical application. This is helpful in engineering for product design, tooling and manufacture etc. RP biomedical applications are design and development of medical devices, instruments, prosthetics and implantation; it is also helpful in planning complex surgical operation. The traditional approach limits the full appreciation of various bony structure movements and therefore the custom implants produced are difficult to measure the anatomy of parts and analyze the changes in facial appearances accurately. Cranioplasty surgery is a surgical correction of a defect in cranial bone by implanting a metal or plastic replacement to restore the missing part. This paper aims to do a comparative study on the dimensional error of CAD and SLS RP Models for reconstruction of cranial defect by comparing the virtual CAD with the physical RP model of a cranial defect.
Abstract: Uterine and oviducal fluids are necessary for
capacitation of the spermatozoa and early embryonic development.
The aim of the present study was to determine the effects of estrous
cycle phases (follicular and luteal) on some biological parameters
(enzymes, electrolytes and total proteins) in uterine and oviducal
secretions of ewes. Oviducal and uterine fluids were collected,
diluted and centrifuged. According to our results, concentrations of
GPT, G6PDH, total proteins, K and Na were significantly (P
Abstract: Images are important in disease research, education,
and clinical medicine. This paper presents a Web Service Platform
(WSP) for support multiple programming languages to access image
from biomedical databases. The main function WSP is to allow web
users access image from biomedical databases. The WSP will
receive web user-s queries. After that, it will send to Querying
Server (QS) and the QS will search and retrieve data from
biomedical databases. Finally, the information will display to the
web users. Simple application is developed and tested for
experiment purpose. Result from experiment indicated WSP can be
used in biomedical environment.
Abstract: This paper proposes a low-cost reconfigurable
architecture for AES algorithm. The proposed architecture separates
SubBytes and MixColumns into two parallel data path, and supports
different bit-width operation for this two data path. As a result, different number of S-box can be supported in this architecture. The
throughput and power consumption can be adjusted by changing the
number of S-box running in this design. Using the TSMC 0.18μm CMOS standard cell library, a very low-cost implementation of 7K
Gates is obtained under 182MHz frequency. The maximum throughput is 360Mbps while using 4 S-Box simultaneously, and the
minimum throughput is 114Mbps while only using 1 S-Box
Abstract: In the national and professional music of oral tradition
of many people in the East there is the metric formula called “ussuli",
that is to say rhythmic constructions of different character and a
composition. Ussuli in translation from Arabic means the law. The
cultural contacts of the ancient and medieval inhabitants of the
Central Asia, India, China, East Turkestan, Iraq, Afghanistan,
Turkey, and Iran have played a certain role in formation of both
musical and dancing heritage of each of these people. During
theatrical shows many dances were performed under the
accompaniment of percussion instruments as nagra, dayulpaz, doll.
The abovementioned tools are used as the obligatory accompanying
tool in an orchestra and at support of dancing acts as the solo tool.
Dynamics of development of a dancing composition, at times
execution of technique of movement depends on various
combinations of ussuli and their receptions of execution.
Abstract: Liposomal magnetofection is the most powerful nonviral method for the nucleic acid delivery into the cultured cancer cells and widely used for in vitro applications. Use of the static magnetic field condition may result in non-uniform distribution of aggregate complexes on the surface of cultured cells. To prevent this, we developed the new device which allows to concentrate aggregate complexes under dynamic magnetic field, assisting more contact of these complexes with cellular membrane and, possibly, stimulating endocytosis. Newly developed device for magnetofection under dynamic gradient magnetic field, “DynaFECTOR", was used to compare transfection efficiency of human liver hepatocellular carcinoma cell line HepG2 with that obtained by lipofection and magnetofection. The effect of two parameters on transfection efficiency, incubation time under dynamic magnetic field and rotation frequency of magnet, was estimated. Liposomal magnetofection under dynamic gradient magnetic field showed the highest transfection efficiency for HepG2 cells.
Abstract: Availability of high dimensional biological datasets such as from gene expression, proteomic, and metabolic experiments can be leveraged for the diagnosis and prognosis of diseases. Many classification methods in this area have been studied to predict disease states and separate between predefined classes such as patients with a special disease versus healthy controls. However, most of the existing research only focuses on a specific dataset. There is a lack of generic comparison between classifiers, which might provide a guideline for biologists or bioinformaticians to select the proper algorithm for new datasets. In this study, we compare the performance of popular classifiers, which are Support Vector Machine (SVM), Logistic Regression, k-Nearest Neighbor (k-NN), Naive Bayes, Decision Tree, and Random Forest based on mock datasets. We mimic common biological scenarios simulating various proportions of real discriminating biomarkers and different effect sizes thereof. The result shows that SVM performs quite stable and reaches a higher AUC compared to other methods. This may be explained due to the ability of SVM to minimize the probability of error. Moreover, Decision Tree with its good applicability for diagnosis and prognosis shows good performance in our experimental setup. Logistic Regression and Random Forest, however, strongly depend on the ratio of discriminators and perform better when having a higher number of discriminators.