Abstract: Amyloid aggregation of polypeptides is related to a
growing number of pathologic states known as amyloid disorders. In
recent years, blocking or reversing amyloid aggregation via the use of
small compounds are considered as two useful approaches in
hampering the development of these diseases. In this research, we
have compared the ability of several manganese-salen derivatives, as
synthetic compounds, and apigenin, as a natural flavonoid, to inhibit
of hen egg-white lysozyme (HEWL) aggregation, as an in vitro
model system.
Different spectroscopic analyses such as Thioflavin T (ThT) and
Anilinonaphthalene-8-sulfonic acid (ANS) fluorescence, Congo red
(CR) absorbance along with transmission electron microscopy were
used in this work to monitor the HEWL aggregation kinetic and
inhibition. Our results demonstrated that both type of compounds
were capable to prevent the formation of lysozyme amyloid
aggregation in vitro. In addition, our data indicated that synthetic
compounds had higher activity to inhibit of the β-sheet structures
relative to natural compound. Regarding the higher antioxidant
activities of the salen derivatives, it can be concluded that in addition
to aromatic rings of each of the compounds, the potent antioxidant
properties of salen derivatives contributes to lower lysozyme fibril
accumulation.
Abstract: It is practically significant to research the traffic flow of intersection because the capacity of intersection affects the efficiency of highway network directly. This paper analyzes the traffic conditions of an intersection in certain urban by the methods of queuing theory and statistical experiment, sets up a corresponding mathematical model and compares it with the actual values. The result shows that queuing theory is applied in the study of intersection traffic flow and it can provide references for the other similar designs.
Abstract: Current transformers (CTs) are used to transform large primary currents to a small secondary current. Since most standard equipment’s are not designed to handle large primary currents the CTs have an important part in any electrical system for the purpose of Metering and Protection both of which are integral in Power system. Now a days due to advancement in solid state technology, the operation times of the protective relays have come to a few cycles from few seconds. Thus, in such a scenario it becomes important to study the transient response of the current transformers as it will play a vital role in the operating of the protective devices.
This paper shows the steady state and transient behavior of current transformers and how it changes with change in connected burden. The transient and steady state response will be captured using the data acquisition software LabVIEW. Analysis is done on the real time data gathered using LabVIEW. Variation of current transformer characteristics with changes in burden will be discussed.
Abstract: Most of the PV systems are designed with transformer for safety purpose with galvanic isolation. However, the transformer is big, heavy and expensive. Also, it reduces the overall frequency of the conversion stage. Generally PV inverter with transformer is having efficiency around 92%–94% only. To overcome these problems, transformerless PV system is introduced. It is smaller, lighter, cheaper and higher in efficiency. However, dangerous leakage current will flow between PV array and the grid due to the stray capacitance. There are different types of configurations available for transformerless inverters like H5, H6, HERIC, oH5, and Dual paralleled buck inverter. But each configuration is suffering from its own disadvantages like high conduction losses, shoot-through issues of switches, dead-time requirements at zero crossing instants of grid voltage to avoid grid shoot-through faults and MOSFET reverse recovery issues. The main objective of the proposed transformerless inverter is to address two key issues: One key issue for a transformerless inverter is that it is necessary to achieve high efficiency compared to other existing inverter topologies. Another key issue is that the inverter configuration should not have any shoot-through issues for higher reliability.
Abstract: Static VAR System (SVS) is a kind of FACTS device which is used in power system primarily for the purpose of voltage and reactive power control. In this paper presents a systematic approach for designing SVS supplementary controller, which is used to improve the damping of power system oscillation. The combined bus voltage and line current (CBVLC) supplementary controller has been developed and incorporated in the SVS control system located at the middle of the series compensated long transmission line. Damping of torsional stresses due to subsynchronous resonance resulting from series capacitive compensation using CBVLC is investigated in this paper. Simulation results are carried out with MATLAB/Simulink on the IEEE first benchmark model (FBM). The simulation results show that the oscillations are satisfactorily damped out by the SVS supplementary controller. Time domain simulation is performed on power system and the results demonstrate the effectiveness of the proposed controller.
Abstract: Flood routing is used in estimating the travel time and attenuation of flood waves as they move downstream a river or channel. The routing procedure is usually classified as hydrologic or hydraulic. Hydraulic methods utilize the equations of continuity and motion. Kinematic routing, a hydraulic technique was used in routing Asa River at Ilorin. The river is of agricultural and industrial importance to Ilorin, the capital of Kwara State, Nigeria. This paper determines the kinematic parameters of kinematic wave velocity, time step, time required to traverse, weighting factor and change in length. Values obtained were 4.67 m/s, 19 secs, 21 secs, 0.75 and 100 m, respectively. These parameters adequately reflect the watershed and flow characteristics essential for the routing. The synthetic unit hydrograph was developed using the Natural Resources Conservation Service (NRCS) method. 24-hr 10yr, 25yr, 50yr and 100yr storm hydrographs were developed from the unit hydrograph using convolution procedures and the outflow hydrographs were obtained for each of 24-hr 10yr, 25yr, 50yr and 100yr indicating 0.11 m3/s, 0.10 m3/s, 0.10 m3/s and 0.10 m3/s attenuations respectively.
Abstract: The objectives of the research are to study patterns of fire location distribution and develop techniques of Geographic Information System application in fire risk assessment for fire planning and management. Fire risk assessment was based on two factors: the vulnerability factor such as building material types, building height, building density and capacity for mitigation factor such as accessibility by road, distance to fire station, distance to hydrants and it was obtained from four groups of stakeholders including firemen, city planners, local government officers and local residents. Factors obtained from all stakeholders were converted into Raster data of GIS and then were superimposed on the data in order to prepare fire risk map of the area showing level of fire risk ranging from high to low. The level of fire risk was obtained from weighted mean of each factor based on the stakeholders. Weighted mean for each factor was obtained by Analytical Hierarchy Analysis.
Abstract: Poly(lactic acid) (PLA) is a biodegradable polymer
which has good mechanical properties, however, its brittleness limits
its usage especially in packaging materials. Therefore, in this work,
PLA based polyurethane films were prepared by synthesizing with
different types of isocyanates; methylene diisocyanate (MDI) and
hexamethylene diisocyanates (HDI). For this purpose, PLA based
polyurethane must have good strength and flexibility. Therefore,
polycaprolactone which has better flexibility were prepared with
PLA. An effective way to endow polylactic acid with toughness is
through chain-extension reaction of the polylactic acid pre-polymer
with polycaprolactone used as chain extender. Polyurethane prepared
from MDI showed brittle behaviour, while, polyurethane prepared
from HDI showed flexibility at same concentrations.
Abstract: Assistive robotics are playing a vital role in advancing the quality of life for disable people. There exist wide range of systems that can control and guide autonomous mobile robots. The objective of the control system is to guide an autonomous mobile robot using the movement of eyes by means of EOG signal. The EOG signal is acquired using Ag/AgCl electrodes and this signal is processed by a microcontroller unit to calculate the eye gaze direction. Then according to the guidance control strategy, the control commands of the wheelchair are sent. The classification of different eye movements allows us to generate simple code for controlling the wheelchair. This work was aimed towards developing a usable and low-cost assistive robotic wheel chair system for disabled people. To live more independent life, the system can be used by the handicapped people especially those with only eye-motor coordination.
Abstract: Virtual reality (VR) is a rapidly emerging computer
interface that attempts to immerse the user completely within an
experimental recreation; thereby, greatly enhancing the overall
impact and providing a much more intuitive link between the
computer and the human participants. The main objective of this
study is to design tractor trailer capable of meeting the customers’
requirements and suitable for rough conditions to be used in
combination with a farm tractor in India. The final concept is capable
of providing arrangements for attaching the trailer to the tractor easily
by pickup hitch, stronger and lighter supporting frame, option of
spare tyre etc. Furthermore, the resulting product design can be sent
via the Internet to customers for comments or marketing purposes.
The virtual prototyping (VP) system therefore facilitates advanced
product design and helps reduce product development time and cost
significantly.
Abstract: The high efficiency power management IC (PMIC) with switching device is presented in this paper. PMIC is controlled with PFM control method in order to have high power efficiency at high current level. Dynamic Threshold voltage CMOS (DT-CMOS) with low on-resistance is designed to decrease conduction loss. The threshold voltage of DT-CMOS drops as the gate voltage increase, resulting in a much higher current handling capability than standard MOSFET. PFM control circuits consist of a generator, AND gate and comparator. The generator is made to have 1.2MHz oscillation voltage. The DC-DC converter based on PFM control circuit and low on-resistance switching device is presented in this paper.
Abstract: For Common R or R-L load to apply arbitrary voltage,
the bridge traditional inverters don’t have any difficulties by PWM
method. However for driving some piezoelectric actuator, arbitrary
voltage not a pulse but a steady voltage should be applied.
Piezoelectric load is considered as R-C load and its voltage does not
decrease even though the applied voltage decreases. Therefore it needs
some special inverter with circuit that can discharge the capacitive
energy. Especially for unidirectional arbitrary voltage driving like as
sine wave, it becomes more difficult problem. In this paper, a charge
and discharge circuit for unidirectional arbitrary voltage driving for
piezoelectric actuator is proposed. The circuit has charging and
discharging switches for increasing and decreasing output voltage.
With the proposed simple circuit, the load voltage can have any
unidirectional level with tens of bandwidth because the load voltage
can be adjusted by switching the charging and discharging switch
appropriately. The appropriateness is proved from the simulation of
the proposed circuit.
Abstract: Each of the countries around the world has different
ways of management and many of them depend on people to
administrate their country. Thailand, for example, empowers the
sovereignty of Thai people under constitution; however, our Thai
voting system is not able to flow fast enough under the current
Political management system. The sovereignty of Thai people is
addressing this problem through representatives during current
elections, in order to set a new policy for the countries ideology to
change in the House and the Cabinet.
This is particularly important in a democracy to be developed
under our current political institution. The Organic Act on Political
Parties 2007 is the establishment we have today that is causing
confrontations within the establishment. There are many political
parties that will soon be abolished. Many political parties have
already been subsidized. This research study is to analyze the legal
problems with the political party establishment under the Organic Act
on Political Parties 2007.
This will focus on the freedom of each political establishment
compared to an effective political operation. Textbooks and academic
papers will be referenced from studies home and abroad.
The study revealed that Organic Act on Political Parties 2007 has
strict provisions on the political structure over the number of
members and the number of branches involved within political
parties system.
Such operations shall be completed within one year; but under the
existing laws the small parties are not able to participate with the
bigger parties. The cities are capable of fulfilling small political party
requirements but fail to become coalesced because the current laws
won't allow them to be united as one. It is important to allow all
independent political parties to join our current political structure.
Board members can’t help the smaller parties to become a large
organization under the existing Thai laws.
Creating a new establishment that functions efficiently throughout
all branches would be one solution to these legal problems between
all political parties. With this new operation, individual political
parties can participate with the bigger parties during elections. Until
current political institutions change their system to accommodate
public opinion, these current Thai laws will continue to be a problem
with all political parties in Thailand.
Abstract: Data Grid is a geographically distributed environment that deals with data intensive application in scientific and enterprise computing. Data replication is a common method used to achieve efficient and fault-tolerant data access in Grids. In this paper, a dynamic data replication strategy, called Enhanced Latest Access Largest Weight (ELALW) is proposed. This strategy is an enhanced version of Latest Access Largest Weight strategy. However, replication should be used wisely because the storage capacity of each Grid site is limited. Thus, it is important to design an effective strategy for the replication replacement task. ELALW replaces replicas based on the number of requests in future, the size of the replica, and the number of copies of the file. It also improves access latency by selecting the best replica when various sites hold replicas. The proposed replica selection selects the best replica location from among the many replicas based on response time that can be determined by considering the data transfer time, the storage access latency, the replica requests that waiting in the storage queue and the distance between nodes. Simulation results utilizing the OptorSim show our replication strategy achieve better performance overall than other strategies in terms of job execution time, effective network usage and storage resource usage.
Abstract: Children today use computer based application in
various activities especially for learning and education. Many of
these tools and application such as the Computer Aided
Pronunciation Training (CAPT) systems enable children to explore
and experience them with little supervision from the adults. In order
for these tools and application to have maximum effect on the
children’s learning and education, it must be attractive to the children
to use them. This could be achieved with the proper user interface
(UI) design. As children grow, so do their ability, taste and
preferences. They interact differently with these applications as they
grow older. This study reviews several articles on how age factors
influence the UI design. The review focuses on age related abilities
such as cognitive, literacy, concentration and feedback requirement.
We have also evaluated few of existing CAPT systems and determine
the influence of age-based factors on the interface design.
Abstract: Combustion phenomenon will be accomplished
effectively by the development of low emission combustor. One of the
significant factors influencing the entire Combustion process is the
mixing between a swirling angular jet (Primary Air) and the
non-swirling inner jet (fuel). To study this fundamental flow, the
chamber had to be designed in such a manner that the combustion
process to sustain itself in a continuous manner and the temperature of
the products is sufficiently below the maximum working temperature
in the turbine. This study is used to develop the effective combustion
with low unburned combustion products by adopting the concept of
high swirl flow and motility of holes in the secondary chamber. The
proper selection of a swirler is needed to reduce emission which can be
concluded from the emission of Nox and CO2. The capture of CO2 is
necessary to mitigate CO2 emissions from natural gas. Thus the
suppression of unburned gases is a meaningful objective for the
development of high performance combustor without affecting turbine
blade temperature.
Abstract: Chittagong is the commercial capital of Bangladesh.
Here Agrabad is one of the most commercial activity centers of
Chittagong. Due to many light industry and commercial land use,
Agrabad to CEPZ road at Agrabad is the only major road of
Chittagong port city which encompasses a huge number of vehicles
every day. It has many junctions which distribute traffic flow in
different roads. In these junctions vehicles gather at some conflict
point to create traffic jam and make the performance of the road
downward. This study is parallel focused on the existing level of
service with traffic volume, capacity, and speed by traffic survey.
After all of these analyses the performance of the road is determined
with finding the factors that influences the performance.
Abstract: Biomass is renewable and sustainable. As an energy source, it will not release extra carbon dioxide into the atmosphere. Hence, tremendous efforts have been made to develop technologies capable of transforming biomass into suitable forms of bio-fuel. One of the viable technologies is gasifying biomass in supercritical water (SCW), a green medium for reactions. While previous studies overwhelmingly selected glucose as a model compound for biomass, the present study adopted fructose for the sake of comparison. The gasification of fructose in SCW was investigated experimentally to evaluate the applicability of supercritical water processes to biomass gasification. Experiments were conducted with an autoclave reactor. Gaseous product mainly consists of H2, CO, CO2, CH4 and C2H6. The effect of two major operating parameters, the reaction temperature (673-873 K) and the dosage of oxidizing agent (0-0.5 stoichiometric oxygen), on the product gas composition, yield and heating value was also examined, with the reaction pressure fixed at 25 MPa.
Abstract: Entrepreneurship has captured the attention of policy-makers, educators and researchers in the last few decades. It has been regarded as a main driver for economic growth, development and employment generation in many countries worldwide. However, scholars have not agreed on the key factors that impact entrepreneurial intention. This study attempts, through an extensive literature review, to provide a holistic view and a more comprehensive understanding of the key factors that lead university undergraduate students to become entrepreneurs. A systematic literature review is conducted and several scientific articles and reports have been examined. The results of this study indicate that there are four main sets of factors: the personality-traits factors, contextual factors, motivational factors, and personal background factors. This research will serve as a base for future studies and will have valuable implications for policy makers and educators.
Abstract: As an emerging business model, cloud computing has been initiated to satisfy the need of organizations and to push Information Technology as a utility. The shift to the cloud has changed the way Information Technology departments are managed traditionally and has raised many concerns for both, public and private sectors.
The purpose of this study is to investigate the possibility of cloud computing services replacing services provided traditionally by IT departments. Therefore, it aims to 1) explore whether organizations in Oman are ready to move to the cloud; 2) identify the deciding factors leading to the adoption or rejection of cloud computing services in Oman; and 3) provide two case studies, one for a successful Cloud provider and another for a successful adopter.
This paper is based on multiple research methods including conducting a set of interviews with cloud service providers and current cloud users in Oman; and collecting data using questionnaires from experts in the field and potential users of cloud services.
Despite the limitation of bandwidth capacity and Internet coverage offered in Oman that create a challenge in adopting the cloud, it was found that many information technology professionals are encouraged to move to the cloud while few are resistant to change.
The recent launch of a new Omani cloud service provider and the entrance of other international cloud service providers in the Omani market make this research extremely valuable as it aims to provide real-life experience as well as two case studies on the successful provision of cloud services and the successful adoption of these services.