Abstract: From a long time age, human beings have chosen their
place of residence and comfort so that those places would have
relatively ideal natural and climatic conditions. For this reason, from
the beginning, the civilizations have been formed in the susceptible
natural regions such as Mesopotamia in Iran and Nile coasts in
Egypt. Also, the core of human density has been made in the form of
an oasis in the deserts.
Regarding the formation and combination of the native
architecture in different regions of Iran, we find that different
properties of these climates have affected frequently the formation of
cities and the architectural combinations of these regions. Thus, the
precise determinations of climatic areas and attaining the climatic
properties of different regions have a great deal of importance in
presenting appropriate and compatible-with-climate designs.
Abstract: The aim of this work is to investigate on the internalflow
patterns in a plate heat exchanger channel, which affect the
rate of sedimentation fouling on the heat transfer surface of the
plate heat exchanger. The research methodologies were the
computer simulation using Computational Fluid Dynamics (CFD)
and the experimental works. COMSOL MULTIPHYSICS™
Version 3.3 was used to simulate the velocity flow fields to verify
the low and high flow regions. The results from the CFD technique
were then compared with the images obtained from the
experiments in which the fouling test rig was set up with a singlechannel
plate heat exchanger to monitor the fouling of calcium
carbonate. Two parameters were varied i.e., the crossing angle of
the two plate: 55/55, 10/10, and 55/10 degree, and the fluid flow
rate at the inlet: 0.0566, 0.1132 and 0.1698 m/s. The type of plate
“GX-12" (the surface area 0.12 m2, the depth 2.9 mm, the width of
fluid flow 215 mm and the thickness of stainless plate of 0.5 mm)
was used in this study. The results indicated that the velocity
distribution for the case of 55/55 degree seems to be very well
organized when compared with the others. Also, an increase in the
inlet velocity resulted in the reduction of fouling rate on the surface
of plate heat exchangers.
Abstract: Hong Kong is one of the regions in the world where Total Fertility Rate (TFR) is very low. In 2001, the TFR dropped until 0.931, which means 1 woman even cannot give birth to one child on average. However, after the reformation of the 'Right of Abode of Hong Kong' in 2001 and the Chinese Central Government loosened the disembarkation procedure of mainland Chinese (mainlander) to enter Hong Kong in 2003; mainlander couples started to cross the border for giving births in Hong Kong. This action raises Hong Kong-s TFR quickly from 0.931 (2001) to 1.094 (2010). Usually, an increasing trend of TFR means a sign of rejuvenation in low-fertility, but in the case of Hong Kong, the increase of TFR does not, rather it generates other population problems. This paper is going to discuss do mainlanders- births help to solve the low-fertility problem in Hong Kong.
Abstract: In the modern manufacturing systems, the use of
thermal cutting techniques using oxyfuel, plasma and laser have
become indispensable for the shape forming of high quality complex
components; however, the conventional chip removal production
techniques still have its widespread space in the manufacturing
industry. Both these types of machining operations require the
positioning of end effector tool at the edge where the cutting process
commences. This repositioning of the cutting tool in every machining
operation is repeated several times and is termed as non-productive
time or airtime motion. Minimization of this non-productive
machining time plays an important role in mass production with high
speed machining. As, the tool moves from one region to the other by
rapid movement and visits a meticulous region once in the whole
operation, hence the non-productive time can be minimized by
synchronizing the tool movements. In this work, this problem is
being formulated as a general travelling salesman problem (TSP) and
a genetic algorithm approach has been applied to solve the same. For
improving the efficiency of the algorithm, the GA has been
hybridized with a noble special heuristic and simulating annealing
(SA). In the present work a novel heuristic in the combination of GA
has been developed for synchronization of toolpath movements
during repositioning of the tool. A comparative analysis of new Meta
heuristic techniques with simple genetic algorithm has been
performed. The proposed metaheuristic approach shows better
performance than simple genetic algorithm for minimization of nonproductive
toolpath length. Also, the results obtained with the help of
hybrid simulated annealing genetic algorithm (HSAGA) are also
found better than the results using simple genetic algorithm only.
Abstract: It is shown that the relationship of tick-borne
encephalitis virus with the human body comes in two ways, the
development of acute infection with the outcome in convalescence
and long stay by the virus in the body, its persistence in the nervous
tissue with periodic reactivation and prolonged circulating
immunoglobulin M. In spite of the fact that tick-borne encephalitis
virus has a tropism for nerve tissue, involvement in the process of
blood cells is an integral component of the infection. Comprehensive
study of the relation of factors of innate and adaptive immunity in the
tick-borne encephalitis providing insight into the features of chronic
disease.
Abstract: Robots- visual perception is a field that is gaining
increasing attention from researchers. This is partly due to emerging
trends in the commercial availability of 3D scanning systems or
devices that produce a high information accuracy level for a variety of
applications. In the history of mining, the mortality rate of mine workers
has been alarming and robots exhibit a great deal of potentials to
tackle safety issues in mines. However, an effective vision system
is crucial to safe autonomous navigation in underground terrains.
This work investigates robots- perception in underground terrains
(mines and tunnels) using statistical region merging (SRM) model.
SRM reconstructs the main structural components of an imagery
by a simple but effective statistical analysis. An investigation is
conducted on different regions of the mine, such as the shaft, stope
and gallery, using publicly available mine frames, with a stream of
locally captured mine images. An investigation is also conducted on a
stream of underground tunnel image frames, using the XBOX Kinect
3D sensors. The Kinect sensors produce streams of red, green and
blue (RGB) and depth images of 640 x 480 resolution at 30 frames per
second. Integrating the depth information to drivability gives a strong
cue to the analysis, which detects 3D results augmenting drivable and
non-drivable regions in 2D. The results of the 2D and 3D experiment
with different terrains, mines and tunnels, together with the qualitative
and quantitative evaluation, reveal that a good drivable region can be
detected in dynamic underground terrains.
Abstract: In this paper, we propose a geometric modeling of
illumination on the patterned image containing etching transistor. This
image is captured by a commercial camera during the inspection of
a TFT-LCD panel. Inspection of defect is an important process in the
production of LCD panel, but the regional difference in brightness,
which has a negative effect on the inspection, is due to the uneven
illumination environment. In order to solve this problem, we present
a geometric modeling of illumination consisting of an interpolation
using the least squares method and 3D modeling using bezier surface.
Our computational time, by using the sampling method, is shorter
than the previous methods. Moreover, it can be further used to correct
brightness in every patterned image.
Abstract: Uranium mining and processing in Brazil occur in a
northeastern area near to Caetité-BA. Several Non-Governmental
Organizations claim that uranium mining in this region is a pollutant
causing health risks to the local population,but those in charge of the
complex extraction and production of“yellow cake" for generating
fuel to the nuclear power plants reject these allegations. This study
aimed at identifying potential problems caused by mining to the
population of Caetité. In this, work,the concentrations of 238U, 232Th
and 40K radioisotopes in the teeth of the Caetité population were
determined by ICP-MS. Teeth are used as bioindicators of
incorporated radionuclides. Cumulative radiation doses in the
skeleton were also determined. The concentration values were below
0.008 ppm, and annual effective dose due to radioisotopes are below
to the reference values. Therefore, it is not possible to state that the
mining process in Caetité increases pollution or radiation exposure in
a meaningful way.
Abstract: The ability to distinguish missense nucleotide
substitutions that contribute to harmful effect from those that do not
is a difficult problem usually accomplished through functional in
vivo analyses. In this study, instead current biochemical methods, the
effects of missense mutations upon protein structure and function
were assayed by means of computational methods and information
from the databases. For this order, the effects of new missense
mutations in exon 5 of PTEN gene upon protein structure and
function were examined. The gene coding for PTEN was identified
and localized on chromosome region 10q23.3 as the tumor
suppressor gene. The utilization of these methods were shown that
c.319G>A and c.341T>G missense mutations that were recognized in
patients with breast cancer and Cowden disease, could be pathogenic.
This method could be use for analysis of missense mutation in others
genes.
Abstract: A new genetic algorithm, termed the 'optimum individual monogenetic genetic algorithm' (OIMGA), is presented whose properties have been deliberately designed to be well suited to hardware implementation. Specific design criteria were to ensure fast access to the individuals in the population, to keep the required silicon area for hardware implementation to a minimum and to incorporate flexibility in the structure for the targeting of a range of applications. The first two criteria are met by retaining only the current optimum individual, thereby guaranteeing a small memory requirement that can easily be stored in fast on-chip memory. Also, OIMGA can be easily reconfigured to allow the investigation of problems that normally warrant either large GA populations or individuals many genes in length. Local convergence is achieved in OIMGA by retaining elite individuals, while population diversity is ensured by continually searching for the best individuals in fresh regions of the search space. The results given in this paper demonstrate that both the performance of OIMGA and its convergence time are superior to those of a range of existing hardware GA implementations.
Abstract: Information regarding early onset neonatal sepsis
(EONS) pathogens may vary between regions. Global perspectives
showed Group B Streptococcal (GBS) as the most common causative
pathogens, but the widespread use of intrapartum antibiotics has
changed the pathogens pattern towards gram negative
microorganisms, especially E. coli. Objective of this study is to
describe the pathogens isolated, to assess current treatment and risk
of EONS. Records of 899 neonates born in three General Hospitals
between 2009 until 2012 were retrospectively reviewed. Proven was
found in 22 (3%) neonates. The majority was isolated with gram
positive organisms, 17 (2.3%). All grams positive and most gram
negative organisms showed sensitivity to the tested antibiotics. Only
two rare gram negative organisms showed total resistant. Male was
possible risk of proven EONS. Although proven EONS remains
uncommon in Malaysia, nonetheless, the effect of intrapartum
antibiotics still required continuous surveillance.
Abstract: This paper presents the design of a ring-shaped tri-axial fore sensor that can be incorporated into the tip of a guidewire for use in minimally invasive surgery (MIS). The designed sensor comprises a ring-shaped structure located at the center of four cantilever beams. The ringdesign allows surgical tools to be easily passed through which largely simplified the integration process. Silicon nanowires (SiNWs) are used aspiezoresistive sensing elementsembeddedon the four cantilevers of the sensor to detect the resistance change caused by the applied load.An integration scheme with new designed guidewire tip structure having two coils at the distal end is presented. Finite element modeling has been employed in the sensor design to find the maximum stress location in order to put the SiNWs at the high stress regions to obtain maximum output. A maximum applicable force of 5 mN is found from modeling. The interaction mechanism between the designed sensor and a steel wire has been modeled by FEM. A linear relationship between the applied load on the steel wire and the induced stress on the SiNWs were observed.
Abstract: Determination of nano particle size is substantial since
the nano particle size exerts a significant effect on various properties
of nano materials. Accordingly, proposing non-destructive, accurate
and rapid techniques for this aim is of high interest. There are some
conventional techniques to investigate the morphology and grain size
of nano particles such as scanning electron microscopy (SEM),
atomic force microscopy (AFM) and X-ray diffractometry (XRD).
Vibrational spectroscopy is utilized to characterize different
compounds and applied for evaluation of the average particle size
based on relationship between particle size and near infrared spectra
[1,4] , but it has never been applied in quantitative morphological
analysis of nano materials. So far, the potential application of nearinfrared
(NIR) spectroscopy with its ability in rapid analysis of
powdered materials with minimal sample preparation, has been
suggested for particle size determination of powdered
pharmaceuticals. The relationship between particle size and diffuse
reflectance (DR) spectra in near infrared region has been applied to
introduce a method for estimation of particle size. Back propagation
artificial neural network (BP-ANN) as a nonlinear model was applied
to estimate average particle size based on near infrared diffuse
reflectance spectra. Thirty five different nano TiO2 samples with
different particle size were analyzed by DR-FTNIR spectrometry and
the obtained data were processed by BP- ANN.
Abstract: The Japanese integrative approach to social systems
can be observed in supply chain management as well as in the
relationship between public and private sectors. Both the Lean
Production System and the Developmental State Model are
characterized by efforts towards the achievement of mutual goals,
resulting in initiatives for capacity building which emphasize the
system level. In Brazil, although organizations undertake efforts to
build capabilities at the individual and organizational levels, the
system level is being neglected. Fieldwork data confirmed the findings
of other studies in terms of the lack of integration in supply chain
management in the Brazilian automobile industry. Moreover, due to
the absence of an active role of the Brazilian state in its relationship
with the private sector, automakers are not fully exploiting the
opportunities in the domestic and regional markets. For promoting a
higher level of economic growth as well as to increase the degree of
spill-over of technologies and techniques, a more integrative approach
is needed.
Abstract: In this paper an alternative visualisation approach of
the wake behind different vehicle body shapes with simplified and
fully-detailed underbody has been proposed and analysed. This
allows for a more clear distinction among the different wake regions.
This visualisation is based on a transformation of the cartesian
coordinates of a chosen wake plane to polar coordinates, using as
filter velocities lower than the freestream. This transformation
produces a polar wake plot that enables the division and
quantification of the wake in a number of sections. In this paper,
local drag has been used to visualise the drag contribution of the flow
by the different sections. Visually, a balanced wake can be observed
by the concentric behaviour of the polar plots. Alternatively,
integration of the local drag of each degree section as a ratio of the
total local drag yields a quantifiable approach of the wake uniformity,
where different sections contribute equally to the local drag, with the
exception of the wheels.
Abstract: In recent years, many researches to mine the exploding Web world, especially User Generated Content (UGC) such as
weblogs, for knowledge about various phenomena and events in the physical world have been done actively, and also Web services
with the Web-mined knowledge have begun to be developed for
the public. However, there are few detailed investigations on how accurately Web-mined data reflect physical-world data. It must be
problematic to idolatrously utilize the Web-mined data in public Web services without ensuring their accuracy sufficiently. Therefore,
this paper introduces the simplest Web Sensor and spatiotemporallynormalized
Web Sensor to extract spatiotemporal data about a target
phenomenon from weblogs searched by keyword(s) representing the
target phenomenon, and tries to validate the potential and reliability of the Web-sensed spatiotemporal data by four kinds of granularity
analyses of coefficient correlation with temperature, rainfall, snowfall,
and earthquake statistics per day by region of Japan Meteorological
Agency as physical-world data: spatial granularity (region-s population
density), temporal granularity (time period, e.g., per day vs. per week), representation granularity (e.g., “rain" vs. “heavy rain"), and
media granularity (weblogs vs. microblogs such as Tweets).
Abstract: lack of convenience condition is one of the problems
in open spaces in hot and dry regions. Nowadays parks and green
landscapes was designed and constructed without any attention to
convenience condition. If this process continues, Citizens will encounter
with some problems. Harsh climatic condition decreases the
efficiency of people-s activities. However there is hard environment
condition in hot and dry regions, Convenience condition has been
provided in Iranian traditional architecture by using techniques and
methods. In this research at the first step characteristics of Iranian
garden that can effect on creating sustainable spaces were
investigated through observation method. Pleasure space in cities will
be created with using these methods and techniques in future cities.
Furthermore the comparison between Iranian garden and landscape in
today-s cities demonstrate the effectiveness of Iranian garden
characteristics on sustainable spaces. Iranian architects used simple
and available methods for creating open architectural spaces. In
addition desirable conditions were provided with taking in to account
both physically and spiritually. Parks and landscapes in future cities
can be designed and constructed with respect to architectural
techniques that used in Iranian gardens in hot and arid regions.
Abstract: The contents of nitrates and nitrites were monitored in
15 ground water resources of a selected region earmarked for the
emergency supply of population. The resources have been selected on
the basis of previous assessment of natural conditions and the
exploitation of territory in the infiltration area as well as the
surroundings of water resources. The health risk analysis carried out
in relation to nitrates and nitrites, which were found to be the most
serious water contaminants, proved, that 14 resources met the health
standards in relation to the assessed criterion and could be included in
crisis plans. Water quality of ground resources may be assessed in the
same way with regard to other contaminants.
Abstract: The purpose of this study was to explore the complex
flow structure a novel active-type micromixer that based on concept of
Wankle-type rotor. The characteristics of this micromixer are two
folds; a rapid mixing of reagents in a limited space due to the
generation of multiple vortices and a graduate increment in dynamic
pressure as the mixed reagents is delivered to the output ports.
Present micro-mixer is consisted of a rotor with shape of triangle
column, a blending chamber and several inlet and outlet ports. The
geometry of blending chamber is designed to make the rotor can be
freely internal rotated with a constant eccentricity ratio. When the
shape of the blending chamber and the rotor are fixed, the effects of
rotating speed of rotor and the relative locations of ports on the mixing
efficiency are numerical studied. The governing equations are
unsteady, two-dimensional incompressible Navier-Stokes equation
and the working fluid is the water. The species concentration equation
is also solved to reveal the mass transfer process of reagents in various
regions then to evaluate the mixing efficiency.
The dynamic mesh technique was implemented to model the
dynamic volume shrinkage and expansion of three individual
sub-regions of blending chamber when the rotor conducted a complete
rotating cycle. Six types of ports configuration on the mixing
efficiency are considered in a range of Reynolds number from 10 to
300. The rapid mixing process was accomplished with the multiple
vortex structures within a tiny space due to the equilibrium of shear
force, viscous force and inertial force. Results showed that the highest
mixing efficiency could be attained in the following conditions: two
inlet and two outlet ports configuration, that is an included angle of 60
degrees between two inlets and an included angle of 120 degrees
between inlet and outlet ports when Re=10.
Abstract: Bones are dynamic and responsive organs, they
regulate their strength and mass according to the loads which they are subjected. Because, the Wnt/β-catenin pathway has profound
effects on the regulation of bone mass, we hypothesized that mechanical loading of bone cells stimulates Wnt/β-catenin signaling, which results in the generation of new bone mass.
Mechanical loading triggers the secretion of the Wnt molecule, which after binding to transmembrane proteins, causes GSK-3β (Glycogen synthase kinase 3 beta) to cease the phosphorylation of β-catenin. β-catenin accumulation in the cytoplasm, followed by its
transport into the nucleus, binding to transcription factors (TCF/LEF)
that initiate transcription of genes related to bone formation. To test this hypothesis, we used TOPGAL (Tcf Optimal Promoter
β-galactosidase) mice in an experiment in which cyclic loads were
applied to the forearm. TOPGAL mice are reporters for cells effected
by the Wnt/β-catenin signaling pathway. TOPGAL mice are genetically engineered mice in which transcriptional activation of β-
catenin, results in the production of an enzyme, β-galactosidase. The
presence of this enzyme allows us to localize transcriptional
activation of β-catenin to individual cells, thereby, allowing us to quantify the effects that mechanical loading has on the Wnt/β-catenin pathway and new bone formation. The ulnae of loaded TOPGAL
mice were excised and transverse slices along different parts of the
ulnar shaft were assayed for the presence of β-galactosidase.
Our results indicate that loading increases β-catenin transcriptional
activity in regions where this pathway is already primed (i.e. where basal activity is already higher) in a load magnitude dependent
manner. Further experiments are needed to determine the temporal and spatial activation of this signaling in relation to bone formation.