Abstract: A series of microarray experiments produces observations
of differential expression for thousands of genes across multiple
conditions.
Principal component analysis(PCA) has been widely used in
multivariate data analysis to reduce the dimensionality of the data in
order to simplify subsequent analysis and allow for summarization of
the data in a parsimonious manner. PCA, which can be implemented
via a singular value decomposition(SVD), is useful for analysis of
microarray data.
For application of PCA using SVD we use the DNA microarray
data for the small round blue cell tumors(SRBCT) of childhood
by Khan et al.(2001). To decide the number of components which
account for sufficient amount of information we draw scree plot.
Biplot, a graphic display associated with PCA, reveals important
features that exhibit relationship between variables and also the
relationship of variables with observations.
Abstract: The increasing usage of antibiotics in the animal
farming industry is an emerging worldwide problem contributing to
the development of antibiotic resistance. The purpose of this work was
to investigate the prevalence and antibiotic resistance profile of
bacterial isolates collected from aquatic environments and meats in a
peri-urban community in Daejeon, Korea. In an antibacterial
susceptibility test, the bacterial isolates showed a high incidence of
resistance (~ 26.04 %) to cefazolin, tetracycline, gentamycin,
norfloxacin, erythromycin and vancomycin. The results from a test for
multiple antibiotic resistance indicated that the isolates were
displaying an approximately 5-fold increase in the incidence of
multiple antibiotic resistance to combinations of two different
antibiotics compared to combinations of three or more antibiotics.
Most of the isolates showed multi-antibiotic resistance, and the
resistance patterns were similar among the sampling groups.
Sequencing data analysis of 16S rRNA showed that most of the
resistant isolates appeared to be dominated by the classes
Betaproteobacteria and Gammaproteobacteria in the phylum
Proteobacteria.
Abstract: Public awareness towards green energy are on the rise and this can be prove by many product being manufactured or prerequired to be made as energy saving devices mainly to save consumer from spending more on utility billing. These schemes are popular nowadays and many homemade appliances are turned into energy saving gadget which attracts the attention of consumers. Knowing the public demands and pattern towards purchasing home appliances thus the idea of “energy saving suction hood (ESSH)" is proposed. The ESSH can be used in many places that require smoke ventilation or even to reduce the room temperature as many conventional suction hoods (CSH) do, but this device works automatically by the usage of sensors that detects the smoke/temperature and automatically spins the exhaust fan. As it turns, the mechanical rotation rotates the AC generator which is coupled together with the fan and then charges the battery. The innovation of this product is, it does not rely on the utility supply as it is also hook up with a solar panel which also charges the battery, Secondly, it generates energy as the exhaust fan mechanically rotates. Thirdly, an energy loop back feature is introduced to this system which will supply for the ventilator fan. Another major innovation is towards interfacing this device with an in house production of generator. This generator is produced by proper design on stator as well as rotor to reduce the losses. A comparison is made between the ESSH and the CSH and result shows that the ESSH saves 172.8kWh/year of utility supply which is used by CSH. This amount of energy can save RM 3.14 from monthly utility bill and a total of RM 37.67 per year. In fact this product can generate 175 Watt of power from generator(75W) and solar panel(100W) that can be used either to supply other household appliances and/or to loop back to supply the fans motor. The innovation of this system is essential for future production of other equipment by using the loopback power method and turning most equipment into a standalone system.
Abstract: With the proliferation of World Wide Web,
development of web-based technologies and the growth in web
content, the structure of a website becomes more complex and web
navigation becomes a critical issue to both web designers and users.
In this paper we define the content and web pages as two important
and influential factors in website navigation and paraphrase the
enhancement in the website navigation as making some useful
changes in the link structure of the website based on the
aforementioned factors. Then we suggest a new method for
proposing the changes using fuzzy approach to optimize the website
architecture. Applying the proposed method to a real case of Iranian
Civil Aviation Organization (CAO) website, we discuss the results of
the novel approach at the final section.
Abstract: Noise has adverse effect on human health and
comfort. Noise not only cause hearing impairment, but it also acts as
a causal factor for stress and raising systolic pressure. Additionally it
can be a causal factor in work accidents, both by marking hazards
and warning signals and by impeding concentration. Industry
workers also suffer psychological and physical stress as well as
hearing loss due to industrial noise. This paper proposes an approach
to enable engineers to point out quantitatively the noisiest source for
modification, while multiple machines are operating simultaneously.
The model with the point source and spherical radiation in a free field
was adopted to formulate the problem. The procedure works very
well in ideal cases (point source and free field). However, most of the
industrial noise problems are complicated by the fact that the noise is
confined in a room. Reflections from the walls, floor, ceiling, and
equipment in a room create a reverberant sound field that alters the
sound wave characteristics from those for the free field. So the model
was validated for relatively low absorption room at NIT Kurukshetra
Central Workshop. The results of validation pointed out that the
estimated sound power of noise sources under simultaneous
conditions were on lower side, within the error limits 3.56 - 6.35 %.
Thus suggesting the use of this methodology for practical
implementation in industry. To demonstrate the application of the
above analytical procedure for estimating the sound power of noise
sources under simultaneous operating conditions, a manufacturing
facility (Railway Workshop at Yamunanagar, India) having five
sound sources (machines) on its workshop floor is considered in this
study. The findings of the case study had identified the two most
effective candidates (noise sources) for noise control in the Railway
Workshop Yamunanagar, India. The study suggests that the
modification in the design and/or replacement of these two identified
noisiest sources (machine) would be necessary so as to achieve an
effective reduction in noise levels. Further, the estimated data allows
engineers to better understand the noise situations of the workplace
and to revise the map when changes occur in noise level due to a
workplace re-layout.
Abstract: The motivation of this work was to find a suitable 3D
scanner for human body parts digitalization in the field of prosthetics
and orthotics. The main project objective is to compare the three
hand-held portable scanners (two optical and one laser) and two
optical tripod scanners. The comparison was made with respect of
scanning detail, simplicity of operation and ability to scan directly on
the human body. Testing was carried out on a plaster cast of the
upper limb and directly on a few volunteers. The objective monitored
parameters were time of digitizing and post-processing of 3D data
and resulting visual data quality. Subjectively, it was considered level
of usage and handling of the scanner. The new tripod was developed
to improve the face scanning conditions. The results provide an
overview of the suitability of different types of scanners.
Abstract: Activity-Based Costing (ABC) represents an
alternative paradigm to traditional cost accounting system and
it often provides more accurate cost information for decision
making such as product pricing, product mix, and make-orbuy
decisions. ABC models the causal relationships between
products and the resources used in their production and traces
the cost of products according to the activities through the use
of appropriate cost drivers. In this paper, the implementation
of the ABC in a manufacturing system is analyzed and a
comparison with the traditional cost based system in terms of
the effects on the product costs are carried out to highlight the
difference between two costing methodologies. By using this
methodology, a valuable insight into the factors that cause the
cost is provided, helping to better manage the activities of the
company.
Abstract: Interactive push VOD system is a new kind of system
that incorporates push technology and interactive technique. It can
push movies to users at high speeds at off-peak hours for optimal
network usage so as to save bandwidth. This paper presents effective
software-based solution for processing mass downstream data at
terminals of interactive push VOD system, where the service can
download movie according to a viewer-s selection. The downstream
data is divided into two catalogs: (1) the carousel data delivered
according to DSM-CC protocol; (2) IP data delivered according to
Euro-DOCSIS protocol. In order to accelerate download speed and
reduce data loss rate at terminals, this software strategy introduces
caching, multi-thread and resuming mechanisms. The experiments
demonstrate advantages of the software-based solution.
Abstract: The possibilities of mobile technology generate new
demands for vocational teacher trainers to transform their approach
to work and to incorporate its usage into their ordinary educational
practice. This paper presents findings of a focus discussion group
(FDG) session on the usage of iPads within a school of vocational
teacher education (SoVTE). It aims to clarify how the teacher
trainers are using iPads and what has changed in their work during
the usage of iPads. The analytical framework bases on content
analysis and expansive learning cycle. It was not only found what
kind of a role iPads played in their daily practices but it brought also
into attention how a cultural change regarding the usage of social
media and mobile technology was desperately needed in the whole
work community. Thus, the FGD was abducted for developing the
knowledge practices of the community of the SoVTE.
Abstract: In the present paper, a numerical investigation has
been carried out to classify and clarify the effects of paramount
parameters on turbulent impinging slot jets. The effects of nozzle-s
exit turbulent intensity, distance between nozzle and impinging plate
are studied at Reynolds number 5000 and 20000. In addition, the
effect of Mach number that is varied between 0.3-0.8 at a constant
Reynolds number 133000 is investigated to elucidate the effect of
compressibility in impinging jet upon a flat plate. The wall that is
located at the same level with nozzle-s exit confines the flow. A
compressible finite volume solver is implemented for simulation the
flow behavior. One equation Spalart-Allmaras turbulent model is
used to simulate turbulent flow at this study. Assessment of the
Spalart-Allmaras turbulent model at high nozzle to plate distance,
and giving enough insights to characterize the effect of Mach number
at high Reynolds number for the complex impinging jet flow are the
remarkable results of this study.
Abstract: The strong international competition as the factor of rising economic development efficiency should not turn into destructive force for models of social orientation. What result Europe received from the accelerated integration without a long transition period of the accepted countries. Correlative relationship between the research and development expenditure and labor productivity, inflation and the rate economy's growth of the USA and the euro zone, employment and gross value added between Old and New Europe is analyzed in this article. The article estimates the differences in economic growth of Old and New Europe. Correlation rate between cycles of the euro area and the countries of Central and the Eastern Europe very much differs, though some of these countries have high correlation as members of the Economic and Monetary Union. Besides, the majority of the countries of Central and the Eastern Europe does not correspond to criteria of an optimum currency area.
Abstract: The concentrations of As, Hg, Co, Cr and Cd were
tested for each soil sample, and their spatial patterns were analyzed
by the semivariogram approach of geostatistics and geographical
information system technology. Multivariate statistic approaches
(principal component analysis and cluster analysis) were used to
identify heavy metal sources and their spatial pattern. Principal
component analysis coupled with correlation between heavy metals
showed that primary inputs of As, Hg and Cd were due to
anthropogenic while, Co, and Cr were associated with pedogenic
factors. Ordinary kriging was carried out to map the spatial patters of
heavy metals. The high pollution sources evaluated was related with
usage of urban and industrial wastewater. The results of this study
helpful for risk assessment of environmental pollution for decision
making for industrial adjustment and remedy soil pollution.
Abstract: Laser Profiler (LP) data from aerial laser surveys have
been increasingly used as topographical inputs to numerical
simulations of flooding and inundation in river basins. LP data has
great potential for reproducing topography, but its effective usage has
not yet been fully established. In this study, flooding and inundation
are simulated numerically using LP data for the Jobaru River basin of
Japan’s Saga Plain. The analysis shows that the topography is
reproduced satisfactorily in the computational domain with urban and
agricultural areas requiring different grid sizes. A 2-D numerical
simulation shows that flood flow behavior changes as grid size is
varied.
Abstract: This paper reviews various approaches that have been
used for the modeling and simulation of large-scale engineering
systems and determines their appropriateness in the development of a
RICS modeling and simulation tool. Bond graphs, linear graphs,
block diagrams, differential and difference equations, modeling
languages, cellular automata and agents are reviewed. This tool
should be based on linear graph representation and supports symbolic
programming, functional programming, the development of noncausal
models and the incorporation of decentralized approaches.
Abstract: A research effort to find the reality of the business of Japan-s software globalization of enterprise-level business software systems has found that while the number of Japan-made enterpriselevel software systems is comparable with those of the other G7 countries, the business is limited to the East and Southeast Asian markets. This indicates that this business has a problem in the European and USA markets. Based on the knowledge that the research has established, the research concludes that the communication problems arise from the lack of individualists' communication styles and foreign language skills in Japan's software globalization is compensated by similarities in certain Japanese cultural factors and Japan's cultural power in the East and Southeast Asian markets and that this business does not have this compensation factor in the European and American markets due to dissimilarities and no cultural power.
Abstract: There is increasing pressure on, and decline of
mopane woodlands due to increasing use and competition for
mopane resources in Zimbabwe in Namibia. Community management strategies, based largely on local knowledge are
evidently unable to cope. Research has generated potentially useful
information for mopane woodland management, but this information
has not been utilized. The work reported in this paper sought to add value to research work conducted on mopane woodlands by
developing effective community-based mopane woodland
management regimes that were based on both local and scientific
knowledge in Zimbabwe and Namibia. The conditions under which research findings were likely to be adopted for mopane woodland management by communities were investigated. The study was conducted at two sites each in Matobo and Omusati Districts in Zimbabwe and Namibia respectively. The mopane woodland
resources in the two study areas were assessed using scientific
ecological methods. A range of participatory methods was used to collect information on use of mopane woodland resources by communities, institutional arrangements governing access to and use
of these resources and to evaluate scientific knowledge for
applicability in local management regimes. Coppicing, thinning and
pollarding were the research generated management methods evaluated. Realities such as availability of woodland resources and
social roles and responsibilities influenced preferences for woodland
management interventions
Abstract: The purposes of this research were 1) to survey the
number of drugstores that unlawful dispense of asthma prescription
drugs, in form of drug combinations in the Phaya Thai district of
Bangkok, 2) to find the steroids contained in that drug combinations,
3) to find a means for informing general public about the dangers of
drugs and for a campaign to stop dispensing them.
Researcher collected drug combinations from 69 drugstores in
Phaya Thai district from Feb 15, 2012 to Mar 15, 2012. The survey
found 30.43%, 21, drug stores, sold asthma drug combinations to
customers without a prescription. These collected samples were
tested for steroid contamination by using Immunochromatography
kits. Eleven samples, 52.38%, were found contaminated with
steroids. In short, there should be control and inspection of
drugstores in the distribution of steroid medications. To improve the
knowledge of self health maintenance and drug usage among public,
Thai Government and Department of Public Health should educate
people about the side effects of using drug combinations and steroids.
Abstract: Complex engineering design problems consist of
numerous factors of varying criticalities. Considering fundamental features of design and inferior details alike will result in an extensive
waste of time and effort. Design parameters should be introduced gradually as appropriate based on their significance relevant to the
problem context. This motivates the representation of design parameters at multiple levels of an abstraction hierarchy. However, developing abstraction hierarchies is an area that is not well
understood. Our research proposes a novel hierarchical abstraction methodology to plan effective engineering designs and processes. It
provides a theoretically sound foundation to represent, abstract and stratify engineering design parameters and tasks according to causality and criticality. The methodology creates abstraction
hierarchies in a recursive and bottom-up approach that guarantees no
backtracking across any of the abstraction levels. The methodology consists of three main phases, representation, abstraction, and layering to multiple hierarchical levels. The effectiveness of the
developed methodology is demonstrated by a design problem.
Abstract: Within the domain of Systems Engineering the need
to perform property aggregation to understand, analyze and manage
complex systems is unequivocal. This can be seen in numerous
domains such as capability analysis, Mission Essential Competencies
(MEC) and Critical Design Features (CDF). Furthermore, the need
to consider uncertainty propagation as well as the sensitivity of
related properties within such analysis is equally as important when
determining a set of critical properties within such a system.
This paper describes this property breakdown in a number of
domains within Systems Engineering and, within the area of CDFs,
emphasizes the importance of uncertainty analysis. As part of this, a
section of the paper describes possible techniques which may be used
within uncertainty propagation and in conclusion an example is
described utilizing one of the techniques for property and uncertainty
aggregation within an aircraft system to aid the determination of
Critical Design Features.