Abstract: This study aimed at investigating whether the
functional brain networks constructed using the initial EEG (obtained
when patients first visited hospital) can be correlated with the
progression of cognitive decline calculated as the changes of
mini-mental state examination (MMSE) scores between the latest and
initial examinations. We integrated the time–frequency cross mutual
information (TFCMI) method to estimate the EEG functional
connectivity between cortical regions, and the network analysis based
on graph theory to investigate the organization of functional networks
in aMCI. Our finding suggested that higher integrated functional
network with sufficient connection strengths, dense connection
between local regions, and high network efficiency in processing
information at the initial stage may result in a better prognosis of the
subsequent cognitive functions for aMCI. In conclusion, the functional
connectivity can be a useful biomarker to assist in prediction of
cognitive declines in aMCI.
Abstract: Brain functional networks based on resting-state EEG
data were compared between patients with mild Alzheimer’s disease
(mAD) and matched patients with amnestic subtype of mild cognitive
impairment (aMCI). We integrated the time–frequency cross mutual
information (TFCMI) method to estimate the EEG functional
connectivity between cortical regions and the network analysis based
on graph theory to further investigate the alterations of functional
networks in mAD compared with aMCI group. We aimed at
investigating the changes of network integrity, local clustering,
information processing efficiency, and fault tolerance in mAD brain
networks for different frequency bands based on several topological
properties, including degree, strength, clustering coefficient, shortest
path length, and efficiency. Results showed that the disruptions of
network integrity and reductions of network efficiency in mAD
characterized by lower degree, decreased clustering coefficient, higher
shortest path length, and reduced global and local efficiencies in the
delta, theta, beta2, and gamma bands were evident. The significant
changes in network organization can be used in assisting
discrimination of mAD from aMCI in clinical.
Abstract: This study is an attempt to raise the awareness of the
stakeholders and the authorities on the sensitivity of Algerian
secondary school teachers of English as a Foreign Language about
the students’ loss of English language skills learned during formal
schooling with effort and at expense and the supposed measures to
arrest that loss. Data was collected from secondary school teachers of
EFL and analyzed quantitatively using a questionnaire containing
open-ended and close-ended questions. The results advocate a
consensus about the need for actions to be adopted to make
assessment techniques outcome-oriented. Most of the participants
were in favor of including curricular activities involving
contextualized learning, problem-solving learning critical selfawareness,
self and peer-assisted learning, use of computers and
internet so as to make learners autonomous.
Abstract: Ongoing landscape transformation is one of the major
causes behind disappearance of traditional landscapes, and lead to
species and resource loss. Tree in paddy fields in the northeast of
Thailand is one of those traditional landscapes. Using three different
historical time layers, we acknowledged the severe deforestation and
rapid urbanization happened in the region. Despite the general
thinking of decline in tree density as consequences, the heterogeneous
trend of changes in total tree density in three studied landscapes denied
the hypothesis that number of trees in paddy field depend on the length
of land use practice. On the other hand, due to selection of planting
new trees on levees, existence of trees in paddy field now relies on
their values for human use. Besides, changes in land use and landscape
structure had a significant impact on decision of which tree density
level is considered as suitable for the landscape.
Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: Artemisia species, which are medically beneficial, are
widespread in temperate regions of both Northern and Southern
hemispheres among which Iran is located. About 35 species of
Artemisia are indigenous in Iran among them some are widespread in
all or most provinces, yet some are restricted to some specific
regions. In this review paper, initially, GC-Mass results of some
experiments done in different provinces of Iran are mentioned among
them some compounds are common among species, some others are
mostly restricted to other species; after that, medical advantages
based on some researches on species of this genus are reviewed;
different qualities such as anti-leishmania, anti-bacteria, antiviral as
well as anti-proliferative could be mentioned.
Abstract: In Capitalism all economic activity rests upon a set of
core institutional foundations, main from which are privately owned
capital assets and profit. How these core institutional foundations are
working in former soviet countries, in particular in Travel and
Tourism Industry of Georgia?
The role of Travel and Tourism as a key pillar of economic growth
is being increasingly recognized by governments in all regions of the
world. For the last few years Georgia succeeded in the World Bank
and IFC “Doing Business” rankings. Despite of that, during decades
totally different statistical data of the tourism sector were provided by
the different State bodies; economic parameters were published few,
or not published at all.
The frequency and extent of property rights violation in Georgia
has repeatedly been the subject of concern for the last decade. Total
value of abrogated by the former Georgian Government private
property is estimated approximately in US$4-5 billion.
Thus, if economic profitability is unknown and property rights are
not protected – that means that the main institutional foundations of
capitalism in Georgia, are not working properly yet, that cause
management problems at all levels of the national Travel and
Tourism industry of Georgia.
Abstract: In this work, we propose the application of Japanese
“Origami” art for a floating function of a small aerial vehicle such as a
hexarotor. A preliminary experiment was conducted using Origami
magic balls mounted under a hexarotor. This magic ball can expand
and shrink using an air pump during free flying. Using this interesting
and functional concept, it promises to reduce the resistance of wind as
well as reduce the energy consumption when the Origami balls are
deflated. This approach can be particularly useful in rescue emergency
situations. Furthermore, there are many unexpected reasons that may
cause the multi-rotor has to land on the surface of water due to
problems with the communication between the aircraft and the ground
station. In addition, a complementary experiment was designed to
prove that the hexarotor can fly maintaining the stability and also,
takes off and lands on the surface of water using air balloons.
Abstract: The main objective of this study was to identify
factors and conditions that motivated and encouraged students
towards the math class and the factors that made this class an
attractive and lovely one. To do this end, questionnaires consisting of
15 questions were distributed among 85 math teachers working in
schools of Zahedan. Having collected and reviewed these
questionnaires, it was shown that doing activity in math class
(activity of students while teaching) and previous math teachers'
behaviors have had much impact on encouraging the students
towards mathematics. Separation of educational classroom of
mathematics from the main classroom (which is decorated with crafts
created by students themselves with regard to math book including
article, wall newspaper, figures and formulas), peers, size and
appearance of math book, first grade teachers in each educational
level, among whom the Elementary first grade teachers had more
importance and impact, were among the most influential and
important factors in this regard. Then, school environment, family,
conducting research related to mathematics, its application in daily
life and other courses and studying the history of mathematics were
categorized as important factors that would increase the students’
interest in mathematics.
Abstract: Voltage sags are the most common power quality
disturbance in the distribution system. It occurs due to the fault in the
electrical network or by the starting of a large induction motor and
this can be solved by using the custom power devices such as
Dynamic Voltage Restorer (DVR). In this paper DVR is proposed to
compensate voltage sags on critical loads dynamically. The DVR
consists of VSC, injection transformers, passive filters and energy
storage (lead acid battery). By injecting an appropriate voltage, the
DVR restores a voltage waveform and ensures constant load voltage.
The simulation and experimental results of a DVR using MATLAB
software shows clearly the performance of the DVR in mitigating
voltage sags.
Abstract: Malathion (ML) is a well known pesticide commonly
used in many agricultural and non-agricultural processes. Its toxicity
has been attributed primarily to the accumulation of acetylcholine
(Ach) at nerve junctions, due to the inhibition of acetylcholinesterase
(AChE). The aim of the current research was to study the protective
effect of the melissa plant extract against reproductive impairment
induced by malathion in 32 male albino rats, and the biological
experiment was divided into four groups (8 in each) that given
malathion (27 mg/kg; 1/50 of the LD50 for an oral dose) and/or
Melissa officinalis (MO) extract (200mg/kg/day) by gavages
technique. The sperm counts, sperm motility, sperm morphology,
FSH, LH, and testosterone levels had been determined in testes
homogenate at the end of the experiment. It is worthy to report that,
rats treated with melissa extract did not show a significant difference
when compared with the control group, while rats given malathion
alone had significantly lower sperm count, sperm motility, and
significantly higher abnormal sperm numbers, than the untreated
control rats as well as having significantly lower serum FSH, LH, and
testosterone levels compared with the control group. Administrations
of melissa extract restore all mentioned histological parameters
towards the control group and the melissa extract had a strong
positive protective effect against malathion toxicity. Results the of
biological parameters were confirmed by the histological
examination of rat testes and indicated that, both control and melissa
groups showing normal seminiferous tubules, while malathion group
testicular tissues had necrosis, edema in the seminiferous tubules and
degeneration of spermatogonial cells lining the seminiferous tubules
with incomplete spermatogenesis. The use of melissa against
malathion improved the histological picture and showing normal
seminiferous tubules with complete spermatogenesis and almost there
was no histopathological changes could be noted.
Abstract: Pomegranate (Punica granatum L.) is an ancient fruit of great medical interest and rich source of antioxidants. Pesticides as dimethoate play a crucial role in the occurrence many diseases in plants, animal and human. Therefore the ability of Pomegranate (Punica granatum L.) to alleviate hepatotoxicity induced by organophosphate pesticide dimethoate was investigated. Albino male rats were divided randomly into 4 groups and kept at 7 animals per group in an environmentally controlled condition for 6 weeks. The first group was served as a control group (basal diet), the second group fed on basal diet supplemented with 5% freeze dried pomegranate seeds, the third group fed on 20 ppm dimethoate contaminated diet and the last group fed on dimethoate contaminated diet supplemented with 5% freeze dried pomegranate seeds. The results revealed that administration of dimethoate caused high significant increased in liver functions: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) activities as well as lipid peroxide (malonaldhyde, MDA); on the other hand high significant decreased on glutathione (GSH), glutathione peroxidase (GPx), albumin and total protein were observed. However addition of 5% freeze dried pomegranate seeds significantly improved all previously mentioned parameters. These results indicate the dimethoate induced hepatotoxicity and highlight the protective effect of pomegranate seeds as a potential protective agent against dimethoate induced hepatotoxicity. This may be attributed to the powerful antioxidants (polyphenols, total phenols, and total flavonoids) which present in high levels in pomegranate as well as improving the immunity by activation of antioxidant enzymes GSH and GPx.
Abstract: In development of floating photovoltaic generation
system, finding a suitable place of installation is as important as
development of economically feasible and stable structure. Especially
since floating photovoltaic system has its facility floating on water
surface, it is extremely important to review the effects of weather
conditions such as wind, water flow and floating matters, various
factors (such as fogs) that can reduce generation efficiency, possibility
of connection with power system, and legal restrictions. The method of
investigating suitable area and resource for development of
tracking-type floating photovoltaic generation system was proposed in
this paper, which can be used for development of floating and ocean
photovoltaic system in the future.
Abstract: This paper aims at finding a suitable neural network
for monitoring congestion level in electrical power systems. In this
paper, the input data has been framed properly to meet the target
objective through supervised learning mechanism by defining normal
and abnormal operating conditions for the system under study. The
congestion level, expressed as line congestion index (LCI), is
evaluated for each operating condition and is presented to the NN
along with the bus voltages to represent the input and target data.
Once, the training goes successful, the NN learns how to deal with a
set of newly presented data through validation and testing
mechanism. The crux of the results presented in this paper rests on
performance comparison of a multi-layered feed forward neural
network with eleven types of back propagation techniques so as to
evolve the best training criteria. The proposed methodology has been
tested on the standard IEEE-14 bus test system with the support of
MATLAB based NN toolbox. The results presented in this paper
signify that the Levenberg-Marquardt backpropagation algorithm
gives best training performance of all the eleven cases considered in
this paper, thus validating the proposed methodology.
Abstract: This research proposes a novel reconstruction protocol
for restoring missing surfaces and low-quality edges and shapes in
photos of artifacts at historical sites. The protocol starts with the
extraction of a cloud of points. This extraction process is based on
four subordinate algorithms, which differ in the robustness and
amount of resultant. Moreover, they use different -but
complementary- accuracy to some related features and to the way
they build a quality mesh. The performance of our proposed protocol
is compared with other state-of-the-art algorithms and toolkits. The
statistical analysis shows that our algorithm significantly outperforms
its rivals in the resultant quality of its object files used to reconstruct
the desired model.
Abstract: Among all FACTS devices, the unified power flow
controller (UPFC) is considered to be the most versatile device.
This is due to its capability to control all the transmission system
parameters (impedance, voltage magnitude, and phase angle). With
the growing interest in UPFC, the attention to develop a mathematical
model has increased. Several models were introduced for UPFC in
literature for different type of studies in power systems. In this paper
a novel comparison study between two dynamic models of UPFC
with their proposed control strategies.
Abstract: Recent perceived climate variability raises concerns
with unprecedented hydrological phenomena and extremes.
Distribution and circulation of the waters of the Earth become
increasingly difficult to determine because of additional uncertainty
related to anthropogenic emissions. The world wide observed
changes in the large-scale hydrological cycle have been related to an
increase in the observed temperature over several decades. Although
the effect of change in climate on hydrology provides a general
picture of possible hydrological global change, new tools and
frameworks for modelling hydrological series with nonstationary
characteristics at finer scales, are required for assessing climate
change impacts. Of the downscaling techniques, dynamic
downscaling is usually based on the use of Regional Climate Models
(RCMs), which generate finer resolution output based on atmospheric
physics over a region using General Circulation Model (GCM) fields
as boundary conditions. However, RCMs are not expected to capture
the observed spatial precipitation extremes at a fine cell scale or at a
basin scale. Statistical downscaling derives a statistical or empirical
relationship between the variables simulated by the GCMs, called
predictors, and station-scale hydrologic variables, called predictands.
The main focus of the paper is on the need for using statistical
downscaling techniques for projection of local hydrometeorological
variables under climate change scenarios. The projections can be then
served as a means of input source to various hydrologic models to
obtain streamflow, evapotranspiration, soil moisture and other
hydrological variables of interest.
Abstract: A generalized vortex lattice method for complex
lifting surfaces with flap and aileron deflection is formulated. The
method is not restricted by the linearized theory assumption and
accounts for all standard geometric lifting surface parameters:
camber, taper, sweep, washout, dihedral, in addition to flap and
aileron deflection. Thickness is not accounted for since the physical
lifting body is replaced by a lattice of panels located on the mean
camber surface. This panel lattice setup and the treatment of different
wake geometries is what distinguish the present work form the
overwhelming majority of previous solutions based on the vortex
lattice method. A MATLAB code implementing the proposed
formulation is developed and validated by comparing our results to
existing experimental and numerical ones and good agreement is
demonstrated. It is then used to study the accuracy of the widely used
classical vortex-lattice method. It is shown that the classical approach
gives good agreement in the clean configuration but is off by as much
as 30% when a flap or aileron deflection of 30° is imposed. This
discrepancy is mainly due the linearized theory assumption
associated with the conventional method. A comparison of the effect
of four different wake geometries on the values of aerodynamic
coefficients was also carried out and it is found that the choice of the
wake shape had very little effect on the results.
Abstract: From an organizational perspective, leaders are a
variation of the same talent pool in that they all score a larger than
average value on the bell curve that maps leadership behaviors and
characteristics, namely competence, vision, communication,
confidence, cultural sensibility, stewardship, empowerment,
authenticity, reinforcement, and creativity. The question that remains
unanswered and essentially unresolved is how to explain the irony
that leaders are so much alike yet their organizations diverge so
noticeably in their ability to innovate. Leadership intersects with
innovation at the point where human interactions get exceedingly
complex and where certain paradoxical forces cohabit: conflict with
conciliation, sovereignty with interdependence, and imagination with
realism. Rather than accepting that leadership is without context, we
argue that leaders are specialists of their domain and that those
effective at leading for innovation are distinct within the broader pool
of leaders. Keeping in view the extensive literature on leadership and
innovation, we carried out a quantitative study with data collected
over a five-year period involving 240 participants from across five
dissimilar companies based in the United States. We found that while
innovation and leadership are, in general, strongly interrelated (r =
.89, p = 0.0), there are five qualities that set leaders apart on
innovation. These qualities include a large radius of trust, a restless
curiosity with a low need for acceptance, an honest sense of self and
other, a sense for knowledge and creativity as the yin and yang of
innovation, and an ability to use multiple senses in the engagement
with followers. When these particular behaviors and characteristics
are present in leaders, organizations out-innovate their rivals by a
margin of 29.3 per cent to gain an unassailable edge in a business
environment that is regularly disruptive. A strategic outcome of this
study is a psychometric scale named iLeadership, proposed with the
underlying evidence, limitations, and potential for leadership and
innovation in organizations.c
Abstract: In many communication and signal processing
systems, it is highly desirable to implement an efficient narrow-band
filter that decimate or interpolate the incoming signals. This paper
presents hardware efficient compensated CIC filter over a narrow
band frequency that increases the speed of down sampling by using
multiplierless decimation filters with polyphase FIR filter structure.
The proposed work analyzed the performance of compensated CIC
filter on the bases of the improvement of frequency response with
reduced hardware complexity in terms of no. of adders and
multipliers and produces the filtered results without any alterations.
CIC compensator filter demonstrated that by using compensation
with CIC filter improve the frequency response in passed of interest
26.57% with the reduction in hardware complexity 12.25%
multiplications per input sample (MPIS) and 23.4% additions per
input sample (APIS) w.r.t. FIR filter respectively.