Is Curcumine Effect Comparable to 5- Aminosalicylic Acid or Budesonide on a Rat Model of Ulcerative Colitis Induced by Trinitrobenzene Sulfonic Acid?

Inflammatory bowel disease (IBD) is a chronic relapsing-remitting condition that afflicts millions of people throughout the world and impairs their daily functions and quality of life. Treatment of IBD depends largely on 5-aminosalicylic acid (5- ASA) and corticosteroids. The present study aimed to clarify the effects of 5-aminosalicylic acid, budesonide and currcumin on 90 male albino rats against trinitrobenzene sulfonic acid (TNB) induced colitis. TNB was injected intrarectally to 50 rats. The other 40 rats served as control groups. Both 5-ASA (in a dose of 120 mg/kg) and budesonide (in a dose of 0.1 mg/kg) were administered daily for one week whereas currcumin was injected intraperitonially (in a dose of 30 mg/kg daily) for 14 days after injection of either TNB in the colitis rats (group B) or saline in control groups (group A). The study included estimation of macroscopic score index, histological examination of H&E stained sections of the colonic tissue, biochemical estimation of myeloperoxidase (MPO), nitric oxide (NO), and caspase-3 levels, in addition to studying the effect of tested drugs on colonic motility. It was found that budesonide and curcumin improved mucosal healing, reduced both NO production and caspase- 3 level. They had the best impact on the disturbed colonic motility in TNBS-model of colitis.

Physicochemical Properties of Microemulsions and their uses in Enhanced Oil Recovery

Use of microemulsion in enhanced oil recovery has become more attractive in recent years because of its high level of extraction efficiency. Experimental investigations have been made on characterization of microemulsions of oil-brinesurfactant/ cosurfactant system for its use in enhanced oil recovery (EOR). Sodium dodecyl sulfate, propan-1-ol and heptane were selected as surfactant, cosurfactant and oil respectively for preparation of microemulsion. The effects of salinity on the relative phase volumes and solubilization parameters have also been studied. As salinity changes from low to high value, phase transition takes place from Winsor I to Winsor II via Winsor III. Suitable microemulsion composition has been selected based on its stability and ability to reduce interfacial tension. A series of flooding experiments have been performed using the selected microemulsion. The flooding experiments were performed in a core flooding apparatus using uniform sand pack. The core holder was tightly packed with uniform sands (60-100 mesh) and saturated with brines of different salinities. It was flooded with the brine at 25 psig and the absolute permeability was calculated from the flow rate of the through sand pack. The sand pack was then flooded with the crude oil at 800 psig to irreducible water saturation. The initial water saturation was determined on the basis of mass balance. Waterflooding was conducted by placing the coreholder horizontally at a constant injection pressure at 200 pisg. After water flooding, when water-cut reached above 95%, around 0.5 pore volume (PV) of the above microemulsion slug was injected followed by chasing water. The experiments were repeated using different composition of microemulsion slug. The additional recoveries were calculated by material balance. Encouraging results with additional recovery more than 20% of original oil in place above the conventional water flooding have been observed.

The Effect of Loperamide and Fentanyl on the Distribution Kinetics of Verapamil in the Lung and Brain in Sprague Dawley Rats

Verapamil has been shown to inhibit fentanyl uptake in vitro and is a potent P-glycoprotein inhibitor. Tissue partitioning of loperamide, a commercially available opioid, is closely controlled by the P-gp efflux transporter. The following studies were designed to evaluate the effect of opioids on verapamil partitioning in the lung and brain, in vivo. Opioid (fentanyl or loperamide) was administered by intravenous infusion to Sprague Dawley rats alone or in combination with verapamil and plasma, with lung and brain tissues were collected at 1, 5, 6, 8, 10 and 60 minutes. Drug dispositions were modeled by recirculatory pharmacokinetic models. Fentanyl slightly increased the verapamil lung (PL) partition coefficient yet decreased the brain (PB) partition coefficient. Furthermore, loperamide significantly increased PLand PB. Fentanyl reduced the verapamil volume of distribution (V1) and verapamil elimination clearance (ClE). Fentanyl decreased verapamil brain partitioning, yet increased verapamil lung partitioning. Also, loperamide increased lung and brain partitioning in vivo. These results suggest that verapamil and fentanyl may be substrates of an unidentified inward transporter in brain tissue and confirm that verapamil and loperamide are substrates of the efflux transporter P-gp.

Evaluation of Market Limitations in the Case of Ecosystem Services

Biodiversity crisis is one of the many crises that started at the turn of the millennia. Concrete form of expression is still disputed, but there is a relatively high consensus regarding the high rate of degradation and the urgent need for action. The strategy of action outlines a strong economic component, together with the recognition of market mechanisms as the most effective policies to protect biodiversity. In this context, biodiversity and ecosystem services are natural assets that play a key role in economic strategies and technological development to promote development and prosperity. Developing and strengthening policies for transition to an economy based on efficient use of resources is the way forward. To emphasize the co-viability specific to the connection economyecosystem services, scientific approach aimed on one hand how to implement policies for nature conservation and on the other hand, the concepts underlying the economic expression of ecosystem services- value, in the context of current technology. Following the analysis of business opportunities associated with changes in ecosystem services was concluded that development of market mechanisms for nature conservation is a trend that is increasingly stronger individualized within recent years. Although there are still many controversial issues that have already given rise to an obvious bias, international organizations and national governments have initiated and implemented in cooperation or independently such mechanisms. Consequently, they created the conditions for convergence between private interests and social interests of nature conservation, so there are opportunities for ongoing business development which leads, among other things, the positive effects on biodiversity. Finally, points out that markets fail to quantify the value of most ecosystem services. Existing price signals reflect at best, only a proportion of the total amount corresponding provision of food, water or fuel.

Design of Gain Scheduled Fuzzy PID Controller

An adaptive fuzzy PID controller with gain scheduling is proposed in this paper. The structure of the proposed gain scheduled fuzzy PID (GS_FPID) controller consists of both fuzzy PI-like controller and fuzzy PD-like controller. Both of fuzzy PI-like and PD-like controllers are weighted through adaptive gain scheduling, which are also determined by fuzzy logic inference. A modified genetic algorithm called accumulated genetic algorithm is designed to learn the parameters of fuzzy inference system. In order to learn the number of fuzzy rules required for the TSK model, the fuzzy rules are learned in an accumulated way. In other words, the parameters learned in the previous rules are accumulated and updated along with the parameters in the current rule. It will be shown that the proposed GS_FPID controllers learned by the accumulated GA perform well for not only the regular linear systems but also the higher order and time-delayed systems.

Building a Personalized Multidimensional Intelligent Learning System

Currently, most of distance learning courses can only deliver standard material to students. Students receive course content passively which leads to the neglect of the goal of education – “to suit the teaching to the ability of students". Providing appropriate course content according to students- ability is the main goal of this paper. Except offering a series of conventional learning services, abundant information available, and instant message delivery, a complete online learning environment should be able to distinguish between students- ability and provide learning courses that best suit their ability. However, if a distance learning site contains well-designed course content and design but fails to provide adaptive courses, students will gradually loss their interests and confidence in learning and result in ineffective learning or discontinued learning. In this paper, an intelligent tutoring system is proposed and it consists of several modules working cooperatively in order to build an adaptive learning environment for distance education. The operation of the system is based on the result of Self-Organizing Map (SOM) to divide students into different groups according to their learning ability and learning interests and then provide them with suitable course content. Accordingly, the problem of information overload and internet traffic problem can be solved because the amount of traffic accessing the same content is reduced.

Detection of Moving Images Using Neural Network

Motion detection is a basic operation in the selection of significant segments of the video signals. For an effective Human Computer Intelligent Interaction, the computer needs to recognize the motion and track the moving object. Here an efficient neural network system is proposed for motion detection from the static background. This method mainly consists of four parts like Frame Separation, Rough Motion Detection, Network Formation and Training, Object Tracking. This paper can be used to verify real time detections in such a way that it can be used in defense applications, bio-medical applications and robotics. This can also be used for obtaining detection information related to the size, location and direction of motion of moving objects for assessment purposes. The time taken for video tracking by this Neural Network is only few seconds.

Sensitivity Computations of Time Relaxation Model with an Application in Cavity Computation

We present a numerical study of the sensitivity of the so called time relaxation family of models of fluid motion with respect to the time relaxation parameter χ on the two dimensional cavity problem. The goal of the study is to compute and compare the sensitivity of the model using finite difference method (FFD) and sensitivity equation method (SEM).

A Technique for Reachability Graph Generation for the Petri Net Models of Parallel Processes

Reachability graph (RG) generation suffers from the problem of exponential space and time complexity. To alleviate the more critical problem of time complexity, this paper presents the new approach for RG generation for the Petri net (PN) models of parallel processes. Independent RGs for each parallel process in the PN structure are generated in parallel and cross-product of these RGs turns into the exhaustive state space from which the RG of given parallel system is determined. The complexity analysis of the presented algorithm illuminates significant decrease in the time complexity cost of RG generation. The proposed technique is applicable to parallel programs having multiple threads with the synchronization problem.

Fingerprint Identification using Discretization Technique

Fingerprint based identification system; one of a well known biometric system in the area of pattern recognition and has always been under study through its important role in forensic science that could help government criminal justice community. In this paper, we proposed an identification framework of individuals by means of fingerprint. Different from the most conventional fingerprint identification frameworks the extracted Geometrical element features (GEFs) will go through a Discretization process. The intention of Discretization in this study is to attain individual unique features that could reflect the individual varianceness in order to discriminate one person from another. Previously, Discretization has been shown a particularly efficient identification on English handwriting with accuracy of 99.9% and on discrimination of twins- handwriting with accuracy of 98%. Due to its high discriminative power, this method is adopted into this framework as an independent based method to seek for the accuracy of fingerprint identification. Finally the experimental result shows that the accuracy rate of identification of the proposed system using Discretization is 100% for FVC2000, 93% for FVC2002 and 89.7% for FVC2004 which is much better than the conventional or the existing fingerprint identification system (72% for FVC2000, 26% for FVC2002 and 32.8% for FVC2004). The result indicates that Discretization approach manages to boost up the classification effectively, and therefore prove to be suitable for other biometric features besides handwriting and fingerprint.

Fatigue Life of an Anti-Roll Bar of a Passenger Vehicle

In the present paper, Fatigue life assessment of an anti-roll bar component of a passenger vehicle, is investigated by ANSYS 11 software. A stress analysis is also carried out by the finite element technique for the determination of highly stressed regions on the bar. Anti-roll bar is a suspension element used at the front, rear, or at both ends of a car that reduces body roll by resisting any unequal vertical motion between the pair of wheels to which it is connected. As a first stage, fatigue damage models proposed by some well-known references and the corresponding assumptions are discussed and some enhancements are proposed. Then, fracture analysis of an anti-roll bar of an automobile is carried out. The analysed type of the anti-roll bar is especially important as many cases are reported about the fracture after a 100,000 km of travel fatigue and fracture conditions. This paper demonstrates fatigue life of an anti-roll bar and then evaluated by experimental analytically results from other researcher.

Plant Varieties Selection System

In the end of the day, meteorological data and environmental data becomes widely used such as plant varieties selection system. Variety plant selection for planted area is of almost importance for all crops, including varieties of sugarcane. Since sugarcane have many varieties. Variety plant non selection for planting may not be adapted to the climate or soil conditions for planted area. Poor growth, bloom drop, poor fruit, and low price are to be from varieties which were not recommended for those planted area. This paper presents plant varieties selection system for planted areas in Thailand from meteorological data and environmental data by the use of decision tree techniques. With this software developed as an environmental data analysis tool, it can analyze resulting easier and faster. Our software is a front end of WEKA that provides fundamental data mining functions such as classify, clustering, and analysis functions. It also supports pre-processing, analysis, and decision tree output with exporting result. After that, our software can export and display data result to Google maps API in order to display result and plot plant icons effectively.

Prediction of the Rear Fuselage Temperature with Radiation Shield

In order to enhance the aircraft survivability, the infrared signatures emitted by hot engine parts should be determined exactly. For its reduction it is necessary for the rear fuselage temperature to be decreased. In this study, numerical modeling of flow fields and heat transfer characteristics of an aircraft nozzle is performed and its temperature distribution along each component wall is predicted. The radiation shield is expected to reduce the skin temperature of rear fuselage. The effect of material characteristic of radiation shield on the heat transfer is also investigated. Through this numerical analysis, design parameters related to the susceptibility of aircraft are examined.

Efficient Pipelined Hardware Implementation of RIPEMD-160 Hash Function

In this paper an efficient implementation of Ripemd- 160 hash function is presented. Hash functions are a special family of cryptographic algorithms, which is used in technological applications with requirements for security, confidentiality and validity. Applications like PKI, IPSec, DSA, MAC-s incorporate hash functions and are used widely today. The Ripemd-160 is emanated from the necessity for existence of very strong algorithms in cryptanalysis. The proposed hardware implementation can be synthesized easily for a variety of FPGA and ASIC technologies. Simulation results, using commercial tools, verified the efficiency of the implementation in terms of performance and throughput. Special care has been taken so that the proposed implementation doesn-t introduce extra design complexity; while in parallel functionality was kept to the required levels.

A 7DOF Manipulator Control in an Unknown Environment based on an Exact Algorithm

An exact algorithm for a n-link manipulator movement amidst arbitrary unknown static obstacles is presented. The algorithm guarantees the reaching of a target configuration of the manipulator in a finite number of steps. The algorithm is reduced to a finite number of calls of a subroutine for planning a trajectory in the presence of known forbidden states. The polynomial approximation algorithm which is used as the subroutine is presented. The results of the exact algorithm implementation for the control of a seven link (7 degrees of freedom, 7DOF) manipulator are given.

Spectrum Analysis with Monte Cralo Simulation, BEAMnrc, for Low Energy X-RAY

BEAMnrc was used to calculate the spectrum and HVL for X-ray Beam during low energy X-ray radiation using tube model: SRO 33/100 /ROT 350 Philips. The results of BEAMnrc simulation and measurements were compared to the IPEM report number 78 and SpekCalc software. Three energies 127, 103 and 84 Kv were used. In these simulation a tungsten anode with 1.2 mm for Be window were used as source. HVLs were calculated from BEAMnrc spectrum with air Kerma method for four different filters. For BEAMnrc one billion particles were used as original particles for all simulations. The results show that for 127 kV, there was maximum 5.2 % difference between BEAMnrc and Measurements and minimum was 0.7% .the maximum 9.1% difference between BEAMnrc and IPEM and minimum was 2.3% .The maximum difference was 3.2% between BEAMnrc and SpekCal and minimum was 2.8%. The result show BEAMnrc was able to satisfactory predict the quantities of Low energy Beam as well as high energy X-ray radiation.

Ambient Intelligence in the Production and Retail Sector: Emerging Opportunities and Potential Pitfalls

This paper provides an introduction into the evolution of information and communication technology and illustrates its usage in the work domain. The paper is sub-divided into two parts. The first part gives an overview over the different phases of information processing in the work domain. It starts by charting the past and present usage of computers in work environments and shows current technological trends, which are likely to influence future business applications. The second part starts by briefly describing, how the usage of computers changed business processes in the past, and presents first Ambient Intelligence applications based on identification and localization information, which are already used in the production and retail sector. Based on current systems and prototype applications, the paper gives an outlook of how Ambient Intelligence technologies could change business processes in the future.

High Level Synthesis of Digital Filters Based On Sub-Token Forwarding

High level synthesis (HLS) is a process which generates register-transfer level design for digital systems from behavioral description. There are many HLS algorithms and commercial tools. However, most of these algorithms consider a behavioral description for the system when a single token is presented to the system. This approach does not exploit extra hardware efficiently, especially in the design of digital filters where common operations may exist between successive tokens. In this paper, we modify the behavioral description to process multiple tokens in parallel. However, this approach is unlike the full processing that requires full hardware replication. It exploits the presence of common operations between successive tokens. The performance of the proposed approach is better than sequential processing and approaches that of full parallel processing as the hardware resources are increased.

Effects of Dual Inoculation of Azotobacter and Mycorrhiza with Nitrogen and Phosphorus Fertilizer Rates on Grain Yield and Some of Characteristics of Spring Safflower

In order to evaluate the Effects of dual inoculation of Azotobacter and Mycorrhiza with Nitrogen and Phosphorus levels on yield and yield components of spring safflower, this study was carried out in field of Farahan university in Markazi province in 2007. A factorial in a randomized complete block design with three replications was used inoculation of Azotobacter (with inoculation and without inoculation) and Mycorrhiza (with inoculation and without inoculation ) with Nitrogen and Phosphorus levels [F0= N0+ P0 (kg.ha-1), F1= N50+ P25(kg.ha-1), F2= N100+ P50(kg.ha-1) and F3= N150+ P75 (kg.ha-1)] on spring safflower (cultivar IL-111). In this study characteristics such as: Harvest index, Hectolitre weight, Root dry weight, Seed yield, Mycorrhizal Colonization Root, Number of days to maturity were assessed. Results indicated that treatment (A0M1F3) with grain yield (1556 kg.ha-1) and treatment (A0M1F0) with grain yield (918 kg.ha-1) were significantly superior to the other treatments and according to calculated, inoculation seeds in plantig date with Azotobacter and Mycorrhiza to cause increase grain yield about 5/38 percentage. we can by inoculation safflower seeds with Azotobacter and Mycorrhiza too easily at the time sowing date. The purpose of this research, study and evaluation the role of biological fixation N and P, to provide for feeds plants.

Economy-Based Computing with WebCom

Grid environments consist of the volatile integration of discrete heterogeneous resources. The notion of the Grid is to unite different users and organisations and pool their resources into one large computing platform where they can harness, inter-operate, collaborate and interact. If the Grid Community is to achieve this objective, then participants (Users and Organisations) need to be willing to donate or share their resources and permit other participants to use their resources. Resources do not have to be shared at all times, since it may result in users not having access to their own resource. The idea of reward-based computing was developed to address the sharing problem in a pragmatic manner. Participants are offered a reward to donate their resources to the Grid. A reward may include monetary recompense or a pro rata share of available resources when constrained. This latter point may imply a quality of service, which in turn may require some globally agreed reservation mechanism. This paper presents a platform for economybased computing using the WebCom Grid middleware. Using this middleware, participants can configure their resources at times and priority levels to suit their local usage policy. The WebCom system accounts for processing done on individual participants- resources and rewards them accordingly.