Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: The study examines the determinants of corporate cash holding of non-financial quoted firms in Nigeria using a sample of fifty four non-financial quoted firms listed on the Nigeria Stock Exchange for the period 1995-2009. Data were sourced from the Annual reports of the sampled firms and analyzed using Generalized Method of Moments(GMM). The study finds evidence supportive of a target adjustment model and that firms can not instantaneously adjust towards the target cash level owing to the fact that adjustment cost being costly,. Also, the result shows significant negative relationship between cash holdings and firm size, net working capital, return on asset and bank relationship and positive relationship with growth opportunities, leverage, inventories, account receivables and financial distress. Furthermore, there is no significant relationship between cash holdings and cash flow. In Nigerian setting, most of the variables that are relevant for explaining cash holdings in the Developed countries are found by this study to be relevant also in Nigeria.
Abstract: This study was set to determine the antimicrobial
activities of brine salting, chlorinated solution, and oil frying
treatments on enteric bacteria and fungi in Rastrineobola argentea
fish from fish landing beaches within L. Victoria basin of western
Kenya. Statistical differences in effectiveness of the different
treatment methods was determined by single factor ANOVA, and
paired two-tail t-Test was performed to compare the differences in
moisture contents before and after storage. Oil fried fish recorded the
lowest microbial loads, sodium chloride at 10% concentration was
the second most effective and chlorinated solution even at 150ppm
was the least effective against the bacteria and fungi in fish. Moisture
contents of the control and treated fish were significantly lower after
storage. These results show that oil frying of fish should be adopted
for processing and preserving Rastrineobola argentea which is the
most abundant and affordable fish species from Lake Victoria.
Abstract: The limit load carrying capacity of functionally
graded materials (FGM) circular plates subjected to an arbitrary
rotationally symmetric loading has been computed. It is provided that
the plate material behaves rigid perfectly plastic and obeys either the
Square or the Tresca yield criterion. To this end the upper and lower
bound principles of limit analysis are employed to determine the
exact value for the limiting load. The correctness of the result are
verified and finally limiting loads for two examples namely; through
radius and through thickness FGM circular plates with simply
supported edges are calculated, respectively and moreover, the values
of critical loading factor are determined.
Abstract: Hydrodesulfurization (HDS) of dibenzothiophene
(DBT) in a high pressure batch reactor was done at 320 °C on
CoMoS/Al2O3-B2O3 (4, 10, and 16 wt. % of Boria) using nhexadecane
as solvent, dimethyldisulfide (DMDS) in tetradecane as
sulfur agent, and stirring at 1000 rpm. The effects of boria were
investigated by using X-ray diffraction (XRD), Temperature
programmed desorption (TPD) of ammonia, and Brunauer-Emmet-
Teller (BET) experiments. The results showed that the catalyst
prepared with low boria content (4 wt. %) had HDS activity (in
pseudo first order kinetic constant basis) value ~1.45 times higher to
that of CoMoS/Al2O3 catalyst.
Abstract: Remarkable changes, like the progress in the ability to understand others' minds, can be identified in several socio-cognitive dimensions between age four and seven. Recently, the parenting attitudes have been considerate as one of the potential extrinsic modifiers of these important developmental aspects. The aim of present study is to explore the relationship among authoritarian parenting attitudes and individual differences in Theory of Mind performance. The study included ninety-two Costarrican preschoolers. Six False-belief tasks, an Advanced Theory of Mind test and the Parenting Attitudes Inventory were used. The results demonstrate that participants with high and low Authoritarian Parenting Received differ in their performance on First and Second Order False-belief tasks, but not in Advanced Theory of Mind tasks. Theoretical considerations about possible explanations regarding these results are discussed and methodological limitations are considered to shed light over future directions.
Abstract: Vernacular building is considered as sustainable in
energy consumption and environment and its thermal performance is
more and more concerned by researchers. This paper investigates the
thermal property of the vernacular building in Lhasa by theoretical
analysis on the aspects of building form, envelope and materials etc.
The values of thermal resistance and thermal capacity of the envelope
are calculated and compared with the current China building code and
modern building case. And it is concluded that Lhasa vernacular
building meets the current China building code of thermal standards
and have better performance in some aspects, which is achieved by
various passive means with close response to local climate conditions.
Abstract: The scientific achievements coming from molecular
biology depend greatly on the capability of computational
applications to analyze the laboratorial results. A comprehensive
analysis of an experiment requires typically the simultaneous study
of the obtained dataset with data that is available in several distinct
public databases. Nevertheless, developing a centralized access to
these distributed databases rises up a set of challenges such as: what
is the best integration strategy, how to solve nomenclature clashes,
how to solve database overlapping data and how to deal with huge
datasets. In this paper we present GeNS, a system that uses a simple and yet innovative approach to address several biological data integration issues. Compared with existing systems, the main
advantages of GeNS are related to its maintenance simplicity and to its coverage and scalability, in terms of number of supported
databases and data types. To support our claims we present the current use of GeNS in two concrete applications. GeNS currently contains more than 140 million of biological relations and it can be
publicly downloaded or remotely access through SOAP web services.
Abstract: Permanent magnet synchronous machines are known
as a good candidate for hybrid electric vehicles due to their unique
merits. However they have two major drawbacks i.e. high cost and
small speed range. In this paper an optimal design of a permanent
magnet machine is presented. A reduction of permanent magnet
material for a constant torque and an extension in speed and torque
ranges are chosen as the optimization aims. For this purpose the
analytical model of the permanent magnet synchronous machine is
derived and the appropriate design algorithm is devised. The genetic
algorithm is then employed to optimize some machine specifications.
Finally the finite element method is used to validate the designed
machine.
Abstract: The objective of present work is to stimulate the
machining of material by electrical discharge machining (EDM) to
give effect of input parameters like discharge current (Ip), pulse on
time (Ton), pulse off time (Toff) which can bring about changes in the
output parameter, i.e. material removal rate. Experimental data was
gathered from die sinking EDM process using copper electrode and
Medium Carbon Steel (AISI 1040) as work-piece. The rules of
membership function (MF) and the degree of closeness to the
optimum value of the MMR are within the upper and lower range of
the process parameters. It was found that proposed fuzzy model is in
close agreement with the experimental results. By Intelligent, model
based design and control of EDM process parameters in this study
will help to enable dramatically decreased product and process
development cycle times.
Abstract: The forest fires in Thailand are annual occurrence which is the cause of air pollutions. This study intended to estimate the emission from forest fire during 2005-2009 using MODerateresolution Imaging Spectro-radiometer (MODIS) sensor aboard the Terra and Aqua satellites, experimental data, and statistical data. The forest fire emission is estimated using equation established by Seiler and Crutzen in 1982. The spatial and temporal variation of forest fire emission is analyzed and displayed in the form of grid density map. From the satellite data analysis suggested between 2005 and 2009, the number of fire hotspots occurred 86,877 fire hotspots with a significant highest (more than 80% of fire hotspots) in the deciduous forest. The peak period of the forest fire is in January to May. The estimation on the emissions from forest fires during 2005 to 2009 indicated that the amount of CO, CO2, CH4, and N2O was about 3,133,845 tons, 47,610.337 tons, 204,905 tons, and 6,027 tons, respectively, or about 6,171,264 tons of CO2eq. They also emitted 256,132 tons of PM10. The year 2007 was found to be the year when the emissions were the largest. Annually, March is the period that has the maximum amount of forest fire emissions. The areas with high density of forest fire emission were the forests situated in the northern, the western, and the upper northeastern parts of the country.
Abstract: Thermo-chemical treatment (TCT) such as pyrolysis
is getting recognized as a valid route for (i) materials and valuable
products and petrochemicals recovery; (ii) waste recycling; and (iii)
elemental characterization. Pyrolysis is also receiving renewed
attention for its operational, economical and environmental
advantages. In this study, samples of polyethylene terephthalate
(PET) and polystyrene (PS) were pyrolysed in a microthermobalance
reactor (using a thermogravimetric-TGA setup). Both
polymers were prepared and conditioned prior to experimentation.
The main objective was to determine the kinetic parameters of the
depolymerization reactions that occur within the thermal degradation
process. Overall kinetic rate constants (ko) and activation energies
(Eo) were determined using the general kinetics theory (GKT)
method previously used by a number of authors. Fitted correlations
were found and validated using the GKT, errors were within ± 5%.
This study represents a fundamental step to pave the way towards the
development of scaling relationship for the investigation of larger
scale reactors relevant to industry.
Abstract: In this work, grinding or microcutting tools in the form of pellets were manufactured using a bounded alumina abrasive grains. The bound used is a vitreous material containing quartz feldspars, kaolinite and a quantity of hematite. The pellets were used in glass grinding process to replace the free abrasive grains lapping process. The study of the elaborated pellets were done to define their effectiveness in the grinding process and to optimize the influence of the pellets elaboration parameters. The obtained results show the existence of an optimal combination of the pellets elaboration parameters for each glass grinding phase (coarse to fine grinding). The final roughness (rms) reached by the elaborated pellets on a BK7 glass surface was about 0.392 μm.
Abstract: The project describes the modeling of various
architectures mechatronics specifically morphologies of robots in an educational environment. Each structure developed by students of
pre-school, primary and secondary was created using the concept of
reverse engineering in a constructivist environment, to later be integrated in educational software that promotes the teaching of
educational Robotics in a virtual and economic environment.
Abstract: In this paper, we present a new method for
incorporating global shift invariance in support vector machines.
Unlike other approaches which incorporate a feature extraction stage,
we first scale the image and then classify it by using the modified
support vector machines classifier. Shift invariance is achieved by
replacing dot products between patterns used by the SVM classifier
with the maximum cross-correlation value between them. Unlike the
normal approach, in which the patterns are treated as vectors, in our
approach the patterns are treated as matrices (or images). Crosscorrelation
is computed by using computationally efficient
techniques such as the fast Fourier transform. The method has been
tested on the ORL face database. The tests indicate that this method
can improve the recognition rate of an SVM classifier.
Abstract: The steady incompressible flow has been solved in cylindrical coordinates in both vapour region and wick structure. The governing equations in vapour region are continuity, Navier-Stokes and energy equations. These equations have been solved using SIMPLE algorithm. For study of parameters variation on heat pipe operation, a benchmark has been chosen and the effect of changing one parameter has been analyzed when the others have been fixed.
Abstract: This paper is concerned with the numerical minimization
of energy functionals in BV (
) (the space of bounded variation
functions) involving total variation for gray-scale 1-dimensional inpainting
problem. Applications are shown by finite element method
and discontinuous Galerkin method for total variation minimization.
We include the numerical examples which show the different recovery
image by these two methods.
Abstract: To realize the vision of ubiquitous computing, it is
important to develop a context-aware infrastructure which can help
ubiquitous agents, services, and devices become aware of their
contexts because such computational entities need to adapt themselves
to changing situations. A context-aware infrastructure manages the
context model representing contextual information and provides
appropriate information. In this paper, we introduce Context-Aware
Middleware for URC System (hereafter CAMUS) as a context-aware
infrastructure for a network-based intelligent robot system and discuss
the ontology-based context modeling and reasoning approach which is
used in that infrastructure.
Abstract: A fuzzy classifier using multiple ellipsoids approximating decision regions for classification is to be designed in this paper. An algorithm called Gustafson-Kessel algorithm (GKA) with an adaptive distance norm based on covariance matrices of prototype data points is adopted to learn the ellipsoids. GKA is able toadapt the distance norm to the underlying distribution of the prototypedata points except that the sizes of ellipsoids need to be determined a priori. To overcome GKA's inability to determine appropriate size ofellipsoid, the genetic algorithm (GA) is applied to learn the size ofellipsoid. With GA combined with GKA, it will be shown in this paper that the proposed method outperforms the benchmark algorithms as well as algorithms in the field.
Abstract: The elimination of ranitidine (a pharmaceutical
compound) has been carried out in the presence of UV-C radiation.
After some preliminary experiments, it has been experienced the no
influence of the gas nature (air or oxygen) bubbled in photolytic
experiments. From simple photolysis experiments the quantum yield
of this compound has been determined. Two photolytic
approximation has been used, the linear source emission in parallel
planes and the point source emission in spherical planes. The
quantum yield obtained was in the proximity of 0.05 mol Einstein-1
regardless of the method used. Addition of free radical promoters
(hydrogen peroxide) increases the ranitidine removal rate while the
use of photocatalysts (TiO2) negatively affects the process.