Abstract: To identify an endothelial cell-specific promoter suitable for vascular-specific targeting, we tested five promoters in vitro--Tie2SE, Tie2LE, ICAM2, Flt-1 and vWF--for promoter activity and specificity in endothelial cells, smooth muscle cells and non-vascular resident cells as well as tissues. These promoters, except for vWF, exhibited good endothelial activity and specificity in vitro. In a syngenic heart transplantation model, the ICAM2 promoter was variably functional in coronary endothelial cells of donor hearts. Thus, the ICAM2, Flt-1, Tie2SE and Tie2LE promoters hold promise for endothelial-specific targeting, but in vitro expression may not predict in vivo expression.
Abstract: This paper describes a new supervised fusion (hybrid)
electrocardiogram (ECG) classification solution consisting of a new
QRS complex geometrical feature extraction as well as a new version
of the learning vector quantization (LVQ) classification algorithm
aimed for overcoming the stability-plasticity dilemma. Toward this
objective, after detection and delineation of the major events of ECG
signal via an appropriate algorithm, each QRS region and also its
corresponding discrete wavelet transform (DWT) are supposed as
virtual images and each of them is divided into eight polar sectors.
Then, the curve length of each excerpted segment is calculated
and is used as the element of the feature space. To increase the
robustness of the proposed classification algorithm versus noise,
artifacts and arrhythmic outliers, a fusion structure consisting of
five different classifiers namely as Support Vector Machine (SVM),
Modified Learning Vector Quantization (MLVQ) and three Multi
Layer Perceptron-Back Propagation (MLP–BP) neural networks with
different topologies were designed and implemented. The new proposed
algorithm was applied to all 48 MIT–BIH Arrhythmia Database
records (within–record analysis) and the discrimination power of the
classifier in isolation of different beat types of each record was
assessed and as the result, the average accuracy value Acc=98.51%
was obtained. Also, the proposed method was applied to 6 number
of arrhythmias (Normal, LBBB, RBBB, PVC, APB, PB) belonging
to 20 different records of the aforementioned database (between–
record analysis) and the average value of Acc=95.6% was achieved.
To evaluate performance quality of the new proposed hybrid learning
machine, the obtained results were compared with similar peer–
reviewed studies in this area.
Abstract: As networking has become popular, Web-learning
tends to be a trend while designing a tool. Moreover, five-axis
machining has been widely used in industry recently; however, it has
potential axial table colliding problems. Thus this paper aims at
proposing an efficient web-learning collision detection tool on
five-axis machining. However, collision detection consumes heavy
resource that few devices can support, thus this research uses a
systematic approach based on web knowledge to detect collision. The
methodologies include the kinematics analyses for five-axis motions,
separating axis method for collision detection, and computer
simulation for verification. The machine structure is modeled as STL
format in CAD software. The input to the detection system is the
g-code part program, which describes the tool motions to produce the
part surface. This research produced a simulation program with C
programming language and demonstrated a five-axis machining
example with collision detection on web site. The system simulates the
five-axis CNC motion for tool trajectory and detects for any collisions
according to the input g-codes and also supports high-performance
web service benefiting from C. The result shows that our method
improves 4.5 time of computational efficiency, comparing to the
conventional detection method.
Abstract: Segmentation techniques based on Active Contour
Models have been strongly benefited from the use of prior information
during their evolution. Shape prior information is captured from
a training set and is introduced in the optimization procedure to
restrict the evolution into allowable shapes. In this way, the evolution
converges onto regions even with weak boundaries. Although
significant effort has been devoted on different ways of capturing
and analyzing prior information, very little thought has been devoted
on the way of combining image information with prior information.
This paper focuses on a more natural way of incorporating the
prior information in the level set framework. For proof of concept
the method is applied on hippocampus segmentation in T1-MR
images. Hippocampus segmentation is a very challenging task, due
to the multivariate surrounding region and the missing boundary
with the neighboring amygdala, whose intensities are identical. The
proposed method, mimics the human segmentation way and thus
shows enhancements in the segmentation accuracy.
Abstract: The main goal of the present work is to decrease the
computational burden for optimum design of steel frames with
frequency constraints using a new type of neural networks called
Wavelet Neural Network. It is contested to train a suitable neural
network for frequency approximation work as the analysis program.
The combination of wavelet theory and Neural Networks (NN)
has lead to the development of wavelet neural networks.
Wavelet neural networks are feed-forward networks using
wavelet as activation function. Wavelets are mathematical
functions within suitable inner parameters, which help them to
approximate arbitrary functions. WNN was used to predict the
frequency of the structures. In WNN a RAtional function with
Second order Poles (RASP) wavelet was used as a transfer
function. It is shown that the convergence speed was faster
than other neural networks. Also comparisons of WNN with
the embedded Artificial Neural Network (ANN) and with
approximate techniques and also with analytical solutions are
available in the literature.
Abstract: In this paper the reference current for Voltage Source
Converter (VSC) of the Shunt Active Power Filter (SAPF) is
generated using Synchronous Reference Frame method,
incorporating the PI controller with anti-windup scheme. The
proposed method improves the harmonic filtering by compensating
the winding up phenomenon caused by the integral term of the PI
controller.
Using Reference Frame Transformation, the current is transformed
from om a - b - c stationery frame to rotating 0 - d - q frame. Using
the PI controller, the current in the 0 - d - q frame is controlled to
get the desired reference signal. A controller with integral action
combined with an actuator that becomes saturated can give some
undesirable effects. If the control error is so large that the integrator
saturates the actuator, the feedback path becomes ineffective because
the actuator will remain saturated even if the process output changes.
The integrator being an unstable system may then integrate to a very
large value, the phenomenon known as integrator windup.
Implementing the integrator anti-windup circuit turns off the
integrator action when the actuator saturates, hence improving the
performance of the SAPF and dynamically compensating harmonics
in the power network. In this paper the system performance is
examined with Shunt Active Power Filter simulation model.
Abstract: In this study we present our developed formative
assessment tool for students' assignments. The tool enables lecturers
to define assignments for the course and assign each problem in each
assignment a list of criteria and weights by which the students' work
is evaluated. During assessment, the lecturers feed the scores for each
criterion with justifications. When the scores of the current
assignment are completely fed in, the tool automatically generates
reports for both students and lecturers. The students receive a report
by email including detailed description of their assessed work, their
relative score and their progress across the criteria along the course
timeline. This information is presented via charts generated
automatically by the tool based on the scores fed in. The lecturers
receive a report that includes summative (e.g., averages, standard
deviations) and detailed (e.g., histogram) data of the current
assignment. This information enables the lecturers to follow the class
achievements and adjust the learning process accordingly. The tool
was examined on two pilot groups of college students that study a
course in (1) Object-Oriented Programming (2) Plane Geometry.
Results reveal that most of the students were satisfied with the
assessment process and the reports produced by the tool. The
lecturers who used the tool were also satisfied with the reports and
their contribution to the learning process.
Abstract: Phishing, or stealing of sensitive information on the
web, has dealt a major blow to Internet Security in recent times. Most
of the existing anti-phishing solutions fail to handle the fuzziness
involved in phish detection, thus leading to a large number of false
positives. This fuzziness is attributed to the use of highly flexible and
at the same time, highly ambiguous HTML language. We introduce a
new perspective against phishing, that tries to systematically prove,
whether a given page is phished or not, using the corresponding
original page as the basis of the comparison. It analyzes the layout of
the pages under consideration to determine the percentage distortion
between them, indicative of any form of malicious alteration. The
system design represents an intelligent system, employing dynamic
assessment which accurately identifies brand new phishing attacks
and will prove effective in reducing the number of false positives.
This framework could potentially be used as a knowledge base, in
educating the internet users against phishing.
Abstract: A new multi inner stage (MIS) cyclone was designed to
remove the acidic gas and fine particles produced from electronic
industry. To characterize gas flow in MIS cyclone, pressure and
velocity distribution were calculated by means of CFD program. Also,
the flow locus of fine particles and particle removal efficiency were
analyzed by Lagrangian method. When outlet pressure condition was
–100mmAq, the efficiency was the best in this study.
Abstract: In cellular networks, limited availability of resources
has to be tapped to its fullest potential. In view of this aspect, a
sophisticated averaging and voting technique has been discussed in
this paper, wherein the radio resources available are utilized to the
fullest value by taking into consideration, several network and radio
parameters which decide on when the handover has to be made and
thereby reducing the load on Base station .The increase in the load
on the Base station might be due to several unnecessary handover
taking place which can be eliminated by making judicious use of the
radio and network parameters.
Abstract: Zero inflated strict arcsine model is a newly developed
model which is found to be appropriate in modeling overdispersed
count data. In this study, we extend zero inflated strict arcsine model
to zero inflated strict arcsine regression model by taking into
consideration the extra variability caused by extra zeros and
covariates in count data. Maximum likelihood estimation method is
used in estimating the parameters for this zero inflated strict arcsine
regression model.
Abstract: In this paper, we present a simple circuit for
Manchester decoding and without using any complicated or
programmable devices. This circuit can decode 90kbps of transmitted
encoded data; however, greater than this transmission rate can be
decoded if high speed devices were used. We also present a new
method for extracting the embedded clock from Manchester data in
order to use it for serial-to-parallel conversion. All of our
experimental measurements have been done using simulation.
Abstract: Recent trends in building constructions in Libya are
more toward tall (high-rise) building projects. As a consequence, a
better estimation of the lateral loading in the design process is
becoming the focal of a safe and cost effective building industry. Byin-
large, Libya is not considered a potential earthquake prone zone,
making wind is the dominant design lateral loads. Current design
practice in the country estimates wind speeds on a mere random
bases by considering certain factor of safety to the chosen wind
speed. Therefore, a need for a more accurate estimation of wind
speeds in Libya was the motivation behind this study. Records of
wind speed data were collected from 22 metrological stations in
Libya, and were statistically analysed. The analysis of more than four
decades of wind speed records suggests that the country can be
divided into four zones of distinct wind speeds. A computer “survey"
program was manipulated to draw design wind speeds contour map
for the state of Libya.
The paper presents the statistical analysis of Libya-s recorded
wind speed data and proposes design wind speed values for a 50-year
return period that covers the entire country.
Abstract: The so-called all-pass filter circuits are commonly
used in the field of signal processing, control and measurement.
Being connected to capacitive loads, these circuits tend to loose their
stability; therefore the elaborate analysis of their dynamic behavior is
necessary. The compensation methods intending to increase the
stability of such circuits are discussed in this paper, including the socalled
lead-lag compensation technique being treated in detail. For
the dynamic modeling, a two-port network model of the all-pass filter
is being derived. The results of the model analysis show, that
effective lead-lag compensation can be achieved, alone by the
optimization of the circuit parameters; therefore the application of
additional electric components are not needed to fulfill the stability
requirement.
Abstract: Paper presents simple sixport principle and its frequency bandwidth. The novel multisixport approach is presented with its possibilities, typical parameters and frequency bandwidth. Practical implementation is shown with its measurement parameters and calibration. The bandwidth circa 1:100 is obtained.
Abstract: Complex engineering design problems consist of
numerous factors of varying criticalities. Considering fundamental features of design and inferior details alike will result in an extensive
waste of time and effort. Design parameters should be introduced gradually as appropriate based on their significance relevant to the
problem context. This motivates the representation of design parameters at multiple levels of an abstraction hierarchy. However, developing abstraction hierarchies is an area that is not well
understood. Our research proposes a novel hierarchical abstraction methodology to plan effective engineering designs and processes. It
provides a theoretically sound foundation to represent, abstract and stratify engineering design parameters and tasks according to causality and criticality. The methodology creates abstraction
hierarchies in a recursive and bottom-up approach that guarantees no
backtracking across any of the abstraction levels. The methodology consists of three main phases, representation, abstraction, and layering to multiple hierarchical levels. The effectiveness of the
developed methodology is demonstrated by a design problem.
Abstract: The purpose of this study is to present a non invasive
method for the marginal adaptation evaluation in class V composite
restorations. Standardized class V cavities, prepared in human
extracted teeth, were filled with Premise (Kerr) composite. The
specimens were thermo cycled. The interfaces were examined by
Optical Coherence Tomography method (OCT) combined with the
confocal microscopy and fluorescence. The optical configuration
uses two single mode directional couplers with a superluminiscent
diode as the source at 1300 nm. The scanning procedure is similar to
that used in any confocal microscope, where the fast scanning is enface
(line rate) and the depth scanning is much slower (at the frame
rate). Gaps at the interfaces as well as inside the composite resin
materials were identified. OCT has numerous advantages which
justify its use in vivo as well as in vitro in comparison with
conventional techniques.
Abstract: The output beam quality of multi transverse modes of
laser, are relatively poor. In order to obtain better beam quality, one
may use an aperture inside the laser resonator. In this case, various
transverse modes can be selected. We have selected various
transverse modes both by simulation and doing experiment. By
inserting a circular aperture inside the diode end-pumped Nd:YAG
pulsed laser resonator, we have obtained 00 TEM , 01 TEM
, 20 TEM and have studied which parameters, can change the mode
shape. Then, we have determined the beam quality factor of TEM00
gaussian mode.
Abstract: In this paper is presented a Geographic Information System (GIS) approach in order to qualify and monitor the broadband lines in efficient way. The methodology used for interpolation is the Delaunay Triangular Irregular Network (TIN). This method is applied for a case study in ISP Greece monitoring 120,000 broadband lines.
Abstract: This paper presents an effective framework for Chinesesyntactic parsing, which includes two parts. The first one is a parsing framework, which is based on an improved bottom-up chart parsingalgorithm, and integrates the idea of the beam search strategy of N bestalgorithm and heuristic function of A* algorithm for pruning, then get multiple parsing trees. The second is a novel evaluation model, which integrates contextual and partial lexical information into traditional PCFG model and defines a new score function. Using this model, the tree with the highest score is found out as the best parsing tree. Finally,the contrasting experiment results are given. Keywords?syntactic parsing, PCFG, pruning, evaluation model.