Abstract: Early detection of breast cancer is considered as a
major public health issue. Breast cancer screening is not generalized
to the entire population due to a lack of resources, staff and
appropriate tools. Systematic screening can result in a volume of data
which can not be managed by present computer architecture, either in
terms of storage capabilities or in terms of exploitation tools. We
propose in this paper to design and develop a data warehouse system
in radiology-senology (DWRS). The aim of such a system is on one
hand, to support this important volume of information providing from
multiple sources of data and images and for the other hand, to help
assist breast cancer screening in diagnosis, education and research.
Abstract: The increasing divorce and fertility rates outside of marriage, the changing values in the last decades have led to a high prevalence of single parent families. Currently, worldwide, singleparent families represent about a quarter of all families. Recent changes occurring in the structure of single-parent families and also the multitude of factors that influence the quality of life of these families require the development of new research tools in order to provide foundations for social policies addressed to this type of family. The purpose of this paper is to present an analysis concerning the quality of life for single parent families in Romania, based on data collected through a research methodology developed by the authors within a scientific research project funded by a national grant called Partnerships in priority areas.
Abstract: This paper presents an architecture to assist in the
development of tools to perform experimental analysis. Existing
implementations of tools based on this architecture are also described
in this paper. These tools are applied to the real world problem of
fault attack emulation and detection in cryptographic algorithms.
Abstract: For a variety of safety and economic reasons, engineering undergraduates in Australia have experienced diminishing access to the real hardware that is typically the embodiment of their theoretical studies. This trend will delay the development of practical competence, decrease the ability to model and design, and suppress motivation. The author has attempted to address this concern by creating a software tool that contains both photographic images of real machinery, and sets of graphical modeling 'tools'. Academics from a range of disciplines can use the software to set tutorial tasks, and incorporate feedback comments for a range of student responses. An evaluation of the software demonstrated that students who had solved modeling problems with the aid of the electronic tutor performed significantly better in formal examinations with similar problems. The 2-D graphical diagnostic routines in the Tutor have the potential to be used in a wider range of problem-solving tasks.
Abstract: The actual grow of the infrastructure in develop country require sophisticate ways manage the operation and control the quality served. This research wants to concentrate in the operation of this infrastructure beyond the construction. The infrastructure-s operation involves an uncertain environment, where unexpected variables are present every day and everywhere. Decision makers need to make right decisions with right information/data analyzed most in real time. To adequately support their decisions and decrease any negative impact and collateral effect, they need to use computational tools called decision support systems (DSS), but now the main source of information came from common users thought an extensive crowdsourcing
Abstract: Identifying protein coding regions in DNA sequences is a basic step in the location of genes. Several approaches based on signal processing tools have been applied to solve this problem, trying to achieve more accurate predictions. This paper presents a new predictor that improves the efficacy of three techniques that use the Fourier Transform to predict coding regions, and that could be computed using an algorithm that reduces the computation load. Some ideas about the combination of the predictor with other methods are discussed. ROC curves are used to demonstrate the efficacy of the proposed predictor, based on the computation of 25 DNA sequences from three different organisms.
Abstract: This paper seeks to give a general idea of the universe of project portfolio management, from its multidisciplinary nature, to the many challenges it raises, passing through the different techniques, models and tools used to solve the multiple problems known. It is intended to contribute to the clarification, with great depth, of the impacts and relationships involved in managing the projects- portfolio. It aims at proposing a technique for the project alignment with the organisational strategy, in order to select projects that later on will be considered in the analysis and selection of the portfolio. We consider the development of a methodology for assessing the project alignment index very relevant in the global market scenario. It can help organisations to gain a greater awareness of market dynamics, speed up the decision process and increase its consistency, thus enabling the strategic alignment and the improvement of the organisational performance.
Abstract: Cosmic showers, from their places of origin in space,
after entering earth generate secondary particles called Extensive Air
Shower (EAS). Detection and analysis of EAS and similar High
Energy Particle Showers involve a plethora of experimental setups
with certain constraints for which soft-computational tools like
Artificial Neural Network (ANN)s can be adopted. The optimality
of ANN classifiers can be enhanced further by the use of Multiple
Classifier System (MCS) and certain data - dimension reduction
techniques. This work describes the performance of certain data
dimension reduction techniques like Principal Component Analysis
(PCA), Independent Component Analysis (ICA) and Self Organizing
Map (SOM) approximators for application with an MCS formed
using Multi Layer Perceptron (MLP), Recurrent Neural Network
(RNN) and Probabilistic Neural Network (PNN). The data inputs are
obtained from an array of detectors placed in a circular arrangement
resembling a practical detector grid which have a higher dimension
and greater correlation among themselves. The PCA, ICA and SOM
blocks reduce the correlation and generate a form suitable for real
time practical applications for prediction of primary energy and
location of EAS from density values captured using detectors in a
circular grid.
Abstract: To understand working features of a micro combustor,
a computer code has been developed to study combustion of
hydrogen–air mixture in a series of chambers with same shape aspect
ratio but various dimensions from millimeter to micrometer level.
The prepared algorithm and the computer code are capable of
modeling mixture effects in different fluid flows including chemical
reactions, viscous and mass diffusion effects. The effect of various
heat transfer conditions at chamber wall, e.g. adiabatic wall, with
heat loss and heat conduction within the wall, on the combustion is
analyzed. These thermal conditions have strong effects on the
combustion especially when the chamber dimension goes smaller and
the ratio of surface area to volume becomes larger.
Both factors, such as larger heat loss through the chamber wall
and smaller chamber dimension size, may lead to the thermal
quenching of micro-scale combustion. Through such systematic
numerical analysis, a proper operation space for the micro-combustor
is suggested, which may be used as the guideline for microcombustor
design. In addition, the results reported in this paper
illustrate that the numerical simulation can be one of the most
powerful and beneficial tools for the micro-combustor design,
optimization and performance analysis.
Abstract: Human genome is not only the evolutionary
summation of all advantageous events, but also houses lesions of
deleterious foot prints. A single gene mutation sometimes may
express multiple consequences in numerous tissues and a linear
relationship of the genotype and the phenotype may often be obscure.
ß Thalassemia minor, a transfusion independent mild anaemia,
coupled with environment among other factors may articulate into
phenotypic pleotropy with Hypocholesterolemia, Vitamin D
deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological
alterations. Occurrence of Pancreatic insufficiency, resultant
steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with
Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor
patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2
4.60% and Hb Adult 84.80% and altered Hemogram) with increased
Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2
(9.5mg/ml) indicate towards a cascade of phenotypic pleotropy
where the ß Thalassemia mutation ,be it in the 5’ cap site of the
mRNA , differential splicing etc in heterozygous state is effecting
several metabolic pathways. Compensatory extramedulary
hematopoiesis may not coped up well with the stressful life style of
the young individual and increased erythropoietic stress with high
demand for cholesterol for RBC membrane synthesis may have
resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia
may have caused the pancreatic insufficiency, leading to Vitamin D
deficiency. This may in turn have caused the secondary
hyperparathyroidism to sustain serum Calcium level. Irritability and
stress intolerance of the patient was a cumulative effect of the vicious
cycle of metabolic compromises. From these findings we propose
that the metabolic deficiencies in the ß Thalassemia mutations may
be considered as the phenotypic display of the pleotropy to explain
the genetic epidemiology.
According to the recommendations from the NIH Workshop on
Gene-Environment Interplay in Common Complex Diseases: Forging
an Integrative Model, study design of observations should be
informed by gene-environment hypotheses and results of a study
(genetic diseases) should be published to inform future hypotheses.
Variety of approaches is needed to capture data on all possible
aspects, each of which is likely to contribute to the etiology of
disease. Speakers also agreed that there is a need for development of
new statistical methods and measurement tools to appraise
information that may be missed out by conventional method where
large sample size is needed to segregate considerable effect.
A meta analytic cohort study in future may bring about significant
insight on to the title comment.
Abstract: Color image segmentation can be considered as a
cluster procedure in feature space. k-means and its adaptive
version, i.e. competitive learning approach are powerful tools
for data clustering. But k-means and competitive learning suffer
from several drawbacks such as dead-unit problem and need to
pre-specify number of cluster. In this paper, we will explore to
use competitive and cooperative learning approach to perform
color image segmentation. In competitive and cooperative
learning approach, seed points not only compete each other, but
also the winner will dynamically select several nearest
competitors to form a cooperative team to adapt to the input
together, finally it can automatically select the correct number
of cluster and avoid the dead-units problem. Experimental
results show that CCL can obtain better segmentation result.
Abstract: Bioinformatics and Cheminformatics use computer as disciplines providing tools for acquisition, storage, processing, analysis, integrate data and for the development of potential applications of biological and chemical data. A chemical database is one of the databases that exclusively designed to store chemical information. NMRShiftDB is one of the main databases that used to represent the chemical structures in 2D or 3D structures. SMILES format is one of many ways to write a chemical structure in a linear format. In this study we extracted Antimicrobial Structures in SMILES format from NMRShiftDB and stored it in our Local Data Warehouse with its corresponding information. Additionally, we developed a searching tool that would response to user-s query using the JME Editor tool that allows user to draw or edit molecules and converts the drawn structure into SMILES format. We applied Quick Search algorithm to search for Antimicrobial Structures in our Local Data Ware House.
Abstract: Domain-specific languages describe specific solutions to problems in the application domain. Traditionally they form a solution composing black-box abstractions together. This, usually, involves non-deep transformations over the target model. In this paper we argue that it is potentially powerful to operate with grey-box abstractions to build a domain-specific software system. We present parametric code templates as grey-box abstractions and conceptual tools to encapsulate and manipulate these templates. Manipulations introduce template-s merging routines and can be defined in a generic way. This involves reasoning mechanisms at the code templates level. We introduce the concept of Neurath Modelling Language (NML) that operates with parametric code templates and specifies a visualisation mapping mechanism for target models. Finally we provide an example of calculating a domain-specific software system with predefined NML elements.
Abstract: This paper introduces a framework that aims to
support the design and development of mobile services. The
traditional innovation process and its supporting instruments in form
of creativity tools, acceptance research and user-generated content
analysis are screened for potentials for improvement. The result is a
reshaped innovation process where acceptance research and usergenerated
content analysis are fully integrated within a creativity
tool. Advantages of this method are the enhancement of design
relevant information for developers and designers and the possibility
to forecast market success.
Abstract: Over recent years, the number of building integrated photovoltaic (BIPV) installations for home systems have been increasing in Malaysia. The paper concerns an analysis - as part of current Research and Development (R&D) efforts - to integrate photovoltaics as an architectural feature of a detached house in the new satellite township of Putrajaya, Malaysia. The analysis was undertaken using calculation and simulation tools to optimize performance of BIPV home system. In this study, a the simulation analysis was undertaken for selected bungalow units based on a long term recorded weather data for city of Kuala Lumpur. The simulation and calculation was done with consideration of a PV panels' tilt and direction, shading effect and economical considerations. A simulation of the performance of a grid connected BIPV house in Kuala Lumpur was undertaken. This case study uses a 60 PV modules with power output of 2.7 kW giving an average of PV electricity output is 255 kWh/month..
Abstract: The significance of emissions from the road transport
sector (such as air pollution, noise, etc) has grown considerably in
recent years. In Australia, 14.3% of national greenhouse gas
emissions in 2000 were the transport sector-s share which 12.9% of
net national emissions were related to a road transport alone.
Considering the growing attention to the green house gas(GHG)
emissions, this paper attempts to provide air pollution modeling
aspects of environmental consequences of the road transport by using
one of the best computer based tools including the Geographic
Information System (GIS). In other word, in this study, GIS and its
applications is explained, models which are used to model air
pollution and GHG emissions from vehicles are described and GIS is
applied in real case study that attempts to forecast GHG emission
from people who travel to work by car in 2031 in Melbourne for
analysing results as thematic maps.
Abstract: Augmented Reality (AR) shows great promises for
its usage as a tool for simulation and verification of design proposal
of new technological systems. Main advantage of augmented reality
application usage is possibility of creation and simulation of new
technological unit before its realization. This may contribute to
increasing of safety and ergonomics and decreasing of economical
aspects of new proposed unit. Virtual model of proposed workcell
could reveal hidden errors which elimination in later stage of new
workcell creation should cause great difficulties. Paper describes
process of such virtual model creation and possibilities of its
simulation and verification by augmented reality tools.
Abstract: Soft topological spaces are considered as mathematical tools for dealing with uncertainties, and a fuzzy topological space
is a special case of the soft topological space. The purpose of this paper is to study soft topological spaces. We introduce some new concepts in soft topological spaces such as soft closed mapping, soft open mappings, soft connected spaces and soft paracompact spaces. We also redefine the concept of soft points such that it is reasonable in soft topological spaces. Moreover, some basic properties of these concepts are explored.
Abstract: Aspheric optical components are an alternative to the use of conventional lenses in the implementation of imaging systems for the visible range. Spherical lenses are capable of producing aberrations. Therefore, they are not able to focus all the light into a single point. Instead, aspherical lenses correct aberrations and provide better resolution even with compact lenses incorporating a small number of lenses.
Metrology of these components is very difficult especially when the resolution requirements increase and insufficient or complexity of conventional tools requires the development of specific approaches to characterization.
This work is part of the problem existed because the objectives are the study and comparison of different methods used to measure surface rays hybrid aspherical lenses.
Abstract: This article first summarizes reasons why current approaches supporting Open Learning and Distance Education need to be complemented by tools permitting lecturers, researchers and students to cooperatively organize the semantic content of Learning related materials (courses, discussions, etc.) into a fine-grained shared semantic network. This first part of the article also quickly describes the approach adopted to permit such a collaborative work. Then, examples of such semantic networks are presented. Finally, an evaluation of the approach by students is provided and analyzed.