Abstract: This article briefly reviews the role of Indian
Pharmacopoeia Commission (IPC) for publications of Indian
Pharmacopoeia (IP) and National formulary of India (NFI) to some of
these anticipated changes, informs constituents about how they can
remain updated about progress and upcoming modifications to
official texts, and invites participation in the standards-setting
process, which are helpful to the practitioners, researchers, educators
and policy makers in the field of health care profession.
Abstract: This study will examine how the therapeutic factors
(therapeutic catharsis-seeking and game-efficacy of the game player)
and self-construal factors (independent and interdependent
self-construal of the game player) as well as social capital factors
(bonding and bridging social capital of the game player) affect
aggression in the game. Results show that both therapeutic
catharsis-seeking and game self-efficacy are particularly important to
the players since they cause the game players’ aggressive tendencies to
be greatly diminished. Independent self-construal reduces the level of
the players’ aggression. Interestingly enough, the bonding social
capital enhances the level of the players’ aggression, while individuals
with bridging social capital did not show any significant effects. The
results and implications will be discussed herein.
Abstract: Distributed applications deployed on LEO satellites
and ground stations require substantial communication between
different members in a constellation to overcome the earth
coverage barriers imposed by GEOs. Applications running on LEO
constellations suffer the earth line-of-sight blockage effect. They
need adequate lab testing before launching to space. We propose
a scalable cloud-based network simulation framework to simulate
problems created by the earth line-of-sight blockage. The framework
utilized cloud IaaS virtual machines to simulate LEO satellites
and ground stations distributed software. A factorial ANOVA
statistical analysis is conducted to measure simulator overhead on
overall communication performance. The results showed a very low
simulator communication overhead. Consequently, the simulation
framework is proposed as a candidate for testing LEO constellations
with distributed software in the lab before space launch.
Abstract: Complex lifting entry was selected for precise landing
performance during the Mars Science Laboratory entry. This study
aims to develop the three-dimensional numerical method for precise
computation and the surface panel method for rapid engineering
prediction. Detailed flow field analysis for Mars exploration mission
was performed by carrying on a series of fully three-dimensional
Navier-Stokes computations. The static aerodynamic performance was
then discussed, including the surface pressure, lift and drag coefficient,
lift-to-drag ratio with the numerical and engineering method.
Computation results shown that the shock layer is thin because of
lower effective specific heat ratio, and that calculated results from both
methods agree well with each other, and is consistent with the
reference data. Aerodynamic performance analysis shows that CG
location determines trim characteristics and pitch stability, and certain
radially and axially shift of the CG location can alter the capsule lifting
entry performance, which is of vital significance for the aerodynamic
configuration design and inner instrument layout of the Mars entry
capsule.
Abstract: In dynamic system theory a mathematical model is
often used to describe their properties. In order to find a transfer
matrix of a dynamic system we need to calculate an inverse matrix.
The paper contains the fusion of the classical theory and the
procedures used in the theory of automated control for calculating the
inverse matrix. The final part of the paper models the given problem
by the Matlab.
Abstract: The paper develops a Non-Linear Model Predictive
Control (NMPC) of water quality in Drinking Water Distribution
Systems (DWDS) based on the advanced non-linear quality dynamics
model including disinfections by-products (DBPs). A special attention
is paid to the analysis of an impact of the flow trajectories prescribed
by an upper control level of the recently developed two-time scale
architecture of an integrated quality and quantity control in DWDS.
The new quality controller is to operate within this architecture in the
fast time scale as the lower level quality controller. The controller
performance is validated by a comprehensive simulation study based
on an example case study DWDS.
Abstract: Knowledge of bone mechanical properties is important
for bone substitutes design and fabrication, and more efficient
prostheses development. The aim of this study is to characterize the
viscoelastic behavior of bone specimens, through stress relaxation
and fatigue tests performed to trabecular bone samples from bovine
femoral heads. Relaxation tests consisted on preloading the samples
at five different magnitudes and evaluate them for 1020 seconds,
adjusting the results to a KWW mathematical model. Fatigue tests
consisted of 700 load cycles and analyze their status at the end of the
tests. As a conclusion we have that between relaxation stress and
each preload there is linear relation and for samples with initial
Young´s modulus greater than 1.5 GPa showed no effects due fatigue
test loading cycles.
Abstract: In the immunologic sense, clinical infection is a state
of failure of the immune system to combat the pathogenic weapon of
the bacteria invading the host. A motile gram negative vibroid
organism associated with marked mono and poly nuclear cell
responses was traced during the examination of a clinical material
from an infected common carp Cyprinus carpio. On primary plate
culture, growth was shown to be pure, dense population of an
Aeromonas-like colony morphotype. The pure isolate was found to
be; Aerobic, facultatively anaerobic, non-halophilic, grew at 0C, and
37C, oxidase positive utilizes glucose through fermentative pathway,
resist 0/129 and novobiocin, produces alanine and lysine
decarboxylases but non-producing ornithine dehydrolases. Tests for
the in vitro determinants of pathogenicity has shown to be; Betahaemolytic
onto blood agar, gelatinase, casienase and amylase
producer. Three in vivo determinants of pathogenicity were tested as,
the lethal dose fifty, the pathogenesis and pathogenicity. It was
evident that 0.1 milliliter of the causal bacterial cell suspension of a
density 1 x 107 CFU/ml injected intramuscularly into an average of
100gms fish toke five days incubation period, then at the day six
morbidity and mortality were initiated. LD50 was recorded at the day
12 post-infection. Use of an LD50 doses to study the pathogenicity,
reveals mononuclear and polynuclear cell responses, on examining
the stained direct films of the clinical materials from the
experimentally infected fish. Re-isolation tests confirm that the reisolant
is same. The course of the infection in natural case was shown
manifestation of; skin ulceration, haemorrhage and descaling. On
evisceration, the internal organs were shown; congestion in the
intestines, spleen and, air sacs. The induced infection showed a
milder form of these manifestations. The grading of the virulence of
this organism was virulent causing chronic course of infections as
indicated from the pathogenesis and pathogenicity studies. Thus the
infectious bacteria were consistent with Aeromonas hydrophila, and
the infection was chronic.
Abstract: Biomass briquette gasification is regarded as a
promising route for efficient briquette use in energy generation, fuels
and other useful chemicals. However, previous research has been
focused on briquette gasification in fixed bed gasifiers such as
updraft and downdraft gasifiers. Fluidised bed gasifier has the
potential to be effectively sized to medium or large scale. This study
investigated the use of fuel briquettes produced from blends of rice
husks and corn cobs biomass, in a bubbling fluidised bed gasifier.
The study adopted a combination of numerical equations and Aspen
Plus simulation software, to predict the product gas (syngas)
composition base on briquette density and biomass composition
(blend ratio of rice husks to corn cobs). The Aspen Plus model was
based on an experimentally validated model from the literature. The
results based on a briquette size 32 mm diameter and relaxed density
range of 500 to 650kg/m3, indicated that fluidisation air required in
the gasifier increased with increase in briquette density, and the
fluidisation air showed to be the controlling factor compared with the
actual air required for gasification of the biomass briquettes. The
mass flowrate of CO2 in the predicted syngas composition increased
with an increase in air flow, in the gasifier, while CO decreased and
H2 was almost constant. The ratio of H2 to CO for various blends of
rice husks and corn cobs did not significantly change at the designed
process air, but a significant difference of 1.0 was observed between
10/90 and 90/10 % blend of rice husks and corn cobs.
Abstract: The research was conducted in order to determine the
organizational socialization levels of nurses working in hospitals in
the form of a descriptive study.
The research population was composed of nurses employed in
public and private sector hospitals in the province of Konya with 0-3
years of professional experience in the hospitals (N=1200); and the
sample was composed of 495 nurses that accepted to take part in the
study voluntarily. Statistical evaluation of data was conducted in
SPSS.16 software.
The results of the study revealed that the total score taken by
nurses at the organizational socialization scale was 262.95; and this
was close to the maximum score. Particularly the departmental
socialization sub-dimension proved to be higher in comparison to the
other two dimensions (organization socialization and task
socialization). Statistically meaningful differences were found in the
levels of organization socialization in relation to the status of
organizational orientation training, level of education and age group.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: Image segmentation and color identification is an
important process used in various emerging fields like intelligent
robotics. A method is proposed for the manipulator to grasp and place
the color object into correct location. The existing methods such as
PSO, has problems like accelerating the convergence speed and
converging to a local minimum leading to sub optimal performance.
To improve the performance, we are using watershed algorithm and
for color identification, we are using EPSO. EPSO method is used to
reduce the probability of being stuck in the local minimum. The
proposed method offers the particles a more powerful global
exploration capability. EPSO methods can determine the particles
stuck in the local minimum and can also enhance learning speed as
the particle movement will be faster.
Abstract: Whey is the lactose rich by-product of the dairy
industry, having good amount of nutrient reservoir. Most abundant
nutrients are lactose, soluble proteins, lipids and mineral salts.
Disposing of whey by most of milk plants which do not have proper
pre-treatment system is the major issue. As a result of which, there
can be significant loss of potential food and energy source. Thus,
whey has been explored as the substrate for the synthesis of different
value added products such as enzymes. β-galactosidase is one of the
important enzymes and has become the major focus of research due
to its ability to catalyze both hydrolytic as well as
transgalactosylation reaction simultaneously. The enzyme is widely
used in dairy industry as it catalyzes the transformation of lactose to
glucose and galactose, making it suitable for the lactose intolerant
people. The enzyme is intracellular in both bacteria and yeast,
whereas for molds, it has an extracellular location. The present work
was carried to utilize the whey for the production of β-galactosidase
enzyme using both yeast and fungal cultures. The yeast isolate
Kluyveromyces marxianus WIG2 and various fungal strains have
been used in the present study. Different disruption techniques have
also been investigated for the extraction of the enzyme produced
intracellularly from yeast cells. Among the different methods tested
for the disruption of yeast cells, SDS-chloroform showed the
maximum β-galactosidase activity. In case of the tested fungal
cultures, Aureobasidium pullulans NCIM 1050 was observed to be
the maximum extracellular enzyme producer.
Abstract: In this study, the pedestrian simulation VISWALK
integration and application platform ant algorithms written program
made to construct a renovation engineering schedule planning mode.
The use of simulation analysis platform construction site when the user
running the simulation, after calculating the user walks in the case of
construction delays, the ant algorithm to find out the minimum delay
time schedule plan, and add volume and unit area deactivated loss of
business computing, and finally to the owners and users of two
different positions cut considerations pick out the best schedule
planning. To assess and validate its effectiveness, this study
constructed the model imported floor of a shopping mall floor
renovation engineering cases. Verify that the case can be found from
the mode of the proposed project schedule planning program can
effectively reduce the delay time and the user's walking mall loss of
business, the impact of the operation on the renovation engineering
facilities in the building to a minimum.
Abstract: Nowadays, the rapid development of CAD systems’
programming environments results in the creation of multiple
downstream applications, which are developed and becoming
increasingly available. CAD based manufacturing simulations is
gradually following the same trend. Drilling is the most popular holemaking
process used in a variety of industries. A specially built piece
of software that deals with the drilling kinematics is presented. The
cutting forces are calculated based on the tool geometry, the cutting
conditions and the tool/work-piece materials. The results are verified
by experimental work. Finally, the response surface methodology
(RSM) is applied and mathematical models of the total thrust force
and the thrust force developed because of the main cutting edges are
proposed.
Abstract: This paper addresses a cutting edge method of
business demand forecasting, based on an empirical probability
function when the historical behavior of the data is random.
Additionally, it presents error determination based on the numerical
method technique ‘propagation of errors.’ The methodology was
conducted characterization and process diagnostics demand planning
as part of the production management, then new ways to predict its
value through techniques of probability and to calculate their mistake
investigated, it was tools used numerical methods. All this based on
the behavior of the data. This analysis was determined considering
the specific business circumstances of a company in the sector of
communications, located in the city of Bogota, Colombia. In
conclusion, using this application it was possible to obtain the
adequate stock of the products required by the company to provide its
services, helping the company reduce its service time, increase the
client satisfaction rate, reduce stock which has not been in rotation
for a long time, code its inventory, and plan reorder points for the
replenishment of stock.
Abstract: Methicillin/multiple-resistant Staphylococcus aureus
(MRSA) are infectious bacteria that are resistant to common
antibiotics. A previous in silico study in our group has identified a
hypothetical protein SAV1226 as one of the potential drug targets. In
this study, we reported the bioinformatics characterization, as well as
cloning, expression, purification and kinetic assays of hypothetical
protein SAV1226 from methicillin/vancomycin-resistant
Staphylococcus aureus Mu50 strain. MALDI-TOF/MS analysis
revealed a low degree of structural similarity with known proteins.
Kinetic assays demonstrated that hypothetical protein SAV1226 is
neither a domain of an ATP dependent dihydroxyacetone kinase nor
of a phosphotransferase system (PTS) dihydroxyacetone kinase,
suggesting that the function of hypothetical protein SAV1226 might
be misannotated on public databases such as UniProt and
InterProScan 5.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: A compound parabolic concentrator (CPC) is a wellknown
non-imaging concentrator that will concentrate the solar
radiation onto receiver (PV cell). One of disadvantage of CPC is has
tall and narrow height compared to its diameter entry aperture area.
Therefore, for economic reason, a truncation had been done by
removed from the top of the full height CPC. This also will lead to
the decreases of concentration ratio but it will be negligible. In this
paper, the flux distribution of untruncated and truncated 2-D hollow
compound parabolic trough concentrator (hCPTC) design is
presented. The untruncated design has initial height H=193.4mm
with concentration ratio C_(2-D)=4. This paper presents the optical
simulation of compound parabolic trough concentrator using raytracing
software TracePro. Results showed that, after the truncation,
the height of CPC reduced 45% from initial height with the
geometrical concentration ratio only decrease 10%. Thus, the cost of
reflector and material dielectric usage can be saved especially at
manufacturing site.