Abstract: Fibre cement plates, often used in construction,
generally are made using quartz as an inert material, cement as a
binder and cellulose as a fibre. This paper, first of all, investigates the
mechanical properties and durability of fibre cement plates when
quartz is both partly and fully replaced with diatomite. Diatomite
does not only have lower density compared to quartz but also has
high pozzolanic activity. The main objective of this paper is the
investigation of the effects of supplementary cementing materials
(SCMs) on the short and long term mechanical properties and
durability characteristics of fibre cement plates prepared using
diatomite. Supplementary cementing materials such as ground
granulated blast furnace slug (GGBS) and fly ash (FA) are used in
this study. Volume proportions of 10, 20, 30 and 40% of GGBS and
FA are used as partial replacement materials to cement. Short and
long term mechanical properties such as compressive and flexural
strengths as well as sorptivity characteristics and mass were
investigated. Consistency and setting time at each replacement levels
of SCMs were also recorded. The effects of using supplementary
cementing materials on the carbonation and sulphate resistance of
fibre cement plates were then experimented. The results, first of all,
show that the use of diatomite as a full or partial replacement to
quartz resulted in a systematic decrease in total mass of the fibre
cement plates. The reduction of mass was largely due to the lower
density and finer particle size of diatomite compared to quartz. The
use of diatomite did not only reduce the mass of these plates but also
increased the compressive strength significantly as a result of its high
pozzolanic activity. The replacement levels of both GGBS and FA
resulted in a systematic decrease in short term compressive strength
with increasing replacement levels. This was essentially expected as
the total rate of hydration is much lower in GGBS and FA than that
of cement. Long term results however, indicated that the compressive
strength of fibre cement plates prepared using both GGBS and FA
increases with time and hence the compressive strength of plates
prepared using SCMs is either equivalent or more than the
compressive strength of plates prepared using cement alone.
Durability characteristics of fibre cement plates prepared using SCMs
were enhanced significantly. Measurements of sopritivty
characteristics were also indicated that the plates prepared using
SCMs has much lower water absorption capacities compared to
plates prepared cement alone. Much higher resistance to carbonation
and sulphate attach were observed with plates prepared using SCMs.
The results presented in this paper show that the use of SCMs does
not only support the production of more sustainable construction
materials but also enhances the mechanical properties and durability
characteristics of fibre cement plates.
Abstract: Background in music analysis: Traditionally, when we
think about a composer’s sketches, the chances are that we are
thinking in terms of the working out of detail, rather than the
evolution of an overall concept. Since music is a “time art,” it follows
that questions of a form cannot be entirely detached from
considerations of time. One could say that composers tend to regard
time either as a place gradually and partially intuitively filled, or they
can look for a specific strategy to occupy it. It seems that the one
thing that sheds light on Stockhausen’s compositional thinking is his
frequent use of “form schemas,” that is often a single-page
representation of the entire structure of a piece.
Background in music technology: Sonic Visualiser is a program
used to study a musical recording. It is an open source application for
viewing, analyzing, and annotating music audio files. It contains a
number of visualisation tools, which are designed with useful default
parameters for musical analysis. Additionally, the Vamp plugin
format of SV supports to provide analysis such as for example
structural segmentation.
Aims: The aim of paper is to show how SV may be used to obtain
a better understanding of the specific musical work, and how the
compositional strategy does impact on musical structures and musical
surfaces. It is known that “traditional” music analytic methods don’t
allow indicating interrelationships between musical surface (which is
perceived) and underlying musical/acoustical structure.
Main Contribution: Stockhausen had dealt with the most diverse
musical problems by the most varied methods. A characteristic which
he had never ceased to be placed at the center of his thought and
works, it was the quest for a new balance founded upon an acute
connection between speculation and intuition. In the case with
Mikrophonie I (1964) for tam-tam and 6 players Stockhausen makes
a distinction between the “connection scheme,” which indicates the
ground rules underlying all versions, and the form scheme, which is
associated with a particular version. The preface to the published
score includes both the connection scheme, and a single instance of a
“form scheme,” which is what one can hear on the CD recording. In
the current study, the insight into the compositional strategy chosen
by Stockhausen was been compared with auditory image, that is, with
the perceived musical surface. Stockhausen’s musical work is
analyzed both in terms of melodic/voice and timbre evolution.
Implications: The current study shows how musical structures
have determined of musical surface. The general assumption is this,
that while listening to music we can extract basic kinds of musical
information from musical surfaces. It is shown that interactive
strategies of musical structure analysis can offer a very fruitful way
of looking directly into certain structural features of music.
Abstract: This paper represents the results of experimental work to investigate the suitability of a waste material (WM) for soft soil stabilisation. In addition, the effect of particle size distribution (PSD) of the waste material on its performance as a soil stabiliser was investigated. The WM used in this study is produced from the incineration processes in domestic energy power plant and it is available in two different grades of fineness (coarse waste material (CWM) and fine waste material (FWM)). An intermediate plasticity silty clayey soil with medium organic matter content has been used in this study. The suitability of the CWM and FWM to improve the physical and engineering properties of the selected soil was evaluated dependant on the results obtained from the consistency limits, compaction characteristics (optimum moisture content (OMC) and maximum dry density (MDD)); along with the unconfined compressive strength test (UCS). Different percentages of CWM were added to the soft soil (3, 6, 9, 12 and 15%) to produce various admixtures. Then the UCS test was carried out on specimens under different curing periods (zero, 7, 14, and 28 days) to find the optimum percentage of CWM. The optimum and other two percentages (either side of the optimum content) were used for FWM to evaluate the effect of the fineness of the WM on UCS of the stabilised soil. Results indicated that both types of the WM used in this study improved the physical properties of the soft soil where the index of plasticity (IP) was decreased significantly. IP was decreased from 21 to 13.64 and 13.10 with 12% of CWM and 15% of FWM respectively. The results of the unconfined compressive strength test indicated that 12% of CWM was the optimum and this percentage developed the UCS value from 202kPa to 500kPa for 28 days cured samples, which is equal, approximately 2.5 times the UCS value for untreated soil. Moreover, this percentage provided 1.4 times the value of UCS for stabilized soil-CWA by using FWM which recorded just under 700kPa after 28 days curing.
Abstract: By the evolvement in technology, the way of
expressing opinions switched direction to the digital world. The
domain of politics, as one of the hottest topics of opinion mining
research, merged together with the behavior analysis for affiliation
determination in texts, which constitutes the subject of this paper.
This study aims to classify the text in news/blogs either as
Republican or Democrat with the minimum number of features. As
an initial set, 68 features which 64 were constituted by Linguistic
Inquiry and Word Count (LIWC) features were tested against 14
benchmark classification algorithms. In the later experiments, the
dimensions of the feature vector reduced based on the 7 feature
selection algorithms. The results show that the “Decision Tree”,
“Rule Induction” and “M5 Rule” classifiers when used with “SVM”
and “IGR” feature selection algorithms performed the best up to
82.5% accuracy on a given dataset. Further tests on a single feature
and the linguistic based feature sets showed the similar results. The
feature “Function”, as an aggregate feature of the linguistic category,
was found as the most differentiating feature among the 68 features
with the accuracy of 81% in classifying articles either as Republican
or Democrat.
Abstract: Presently a significant portion of the Earth's
population does not have access to healthy food. Either because they
cannot afford it or because they do not know which one are they. The
aim of the VII th Framework Chance project (Nr. 266331) supported
by the European Union has been to develop relatively cheap food
with favourable nutritional value and it should have acceptable
quality for consumers. As one task of the project we manufactured
bread products as a basic food. We examined the enrichment of bread
products with four kinds of bran, with a special milling product of
grain industry (aleurone-rich flour) and with a soy-based sprouted
additive. The applied concentration of the six mentioned additives
has been optimized and the physical properties of the bread products
were monitored. The weight/density of the enriched breads increased
a bit, however the volume and height decreased slightly compared to
the corresponding data of the control bread. The optimized
composition of the final product is favourably affected by these
additives having highly preferred composition from nutritional point
of view.
Abstract: More than 3000 plants of notable phyto-therapeutic
value grow in South Africa; these include Cissampelos capensis,
commonly known in Afrikaans as dawidjie or dawidjiewortel. C.
capensis is the most significant and popular medicinal plant used by
the Khoisan as well as other rural groups in the Western region of
South Africa. Its rhizomes are traditionally used to treat male fertility
problems. Yet, no studies have investigated the effects of this plant or
its extracts on human spermatozoa. Therefore, this study aimed at
investigating the effects of C. capensis rhizome extract (CRE)
fractions on ejaculated human spermatozoa in vitro. Spermatozoa
from a total of 77 semen samples were washed with human tubular
fluid medium supplemented with bovine serum albumin (HTF-BSA)
and incubated for 2 hours with 20 μg/ml progesterone (P4) followed
by incubation with different concentrations (0, 0.05, 0.5, 5, 50, 200
μg/ml) of fractionated CRE (F1=0% MeOH, F2=30% MeOH,
F3=60% MeOH and F4=100% MeOH) for 1.5 hours at 37°C. A
sample without addition of CRE fractions served as control. Samples
were analyzed for sperm motility, reactive oxygen species (ROS),
DNA-fragmentation, acrosome reaction and capacitation. Results
showed that F1 resulted in significantly higher values for ROS,
capacitation and hyper-activation compared to F2, F3, and F4 with
P4-stimulated samples generally having higher values. No significant
effect was found for the other parameters. In conclusion, alkaloids
present in F1 of CRE appear to have triggered sperm intrinsic ROS
production leading to sperm capacitation and acrosome reaction
induced by P4.
Abstract: Methicillin/multiple-resistant Staphylococcus aureus
(MRSA) are infectious bacteria that are resistant to common
antibiotics. A previous in silico study in our group has identified a
hypothetical protein SAV1226 as one of the potential drug targets. In
this study, we reported the bioinformatics characterization, as well as
cloning, expression, purification and kinetic assays of hypothetical
protein SAV1226 from methicillin/vancomycin-resistant
Staphylococcus aureus Mu50 strain. MALDI-TOF/MS analysis
revealed a low degree of structural similarity with known proteins.
Kinetic assays demonstrated that hypothetical protein SAV1226 is
neither a domain of an ATP dependent dihydroxyacetone kinase nor
of a phosphotransferase system (PTS) dihydroxyacetone kinase,
suggesting that the function of hypothetical protein SAV1226 might
be misannotated on public databases such as UniProt and
InterProScan 5.
Abstract: To ensure targeting of apoferritin nanocarrier with
encapsulated doxorubicin drug, we used a peptide linker based on a
protein G with N-terminus affinity towards Fc region of antibodies.
To connect the peptide to the surface of apoferritin, the C-terminus of
peptide was made of cysteine with affinity to gold. The surface of
apoferritin with encapsulated doxorubicin (APODOX) was coated
either with gold nanoparticles (APODOX-Nano) or gold(III) chloride
hydrate reduced with sodium borohydride (APODOX-HAu). The
reduction with sodium borohydride caused a loss of doxorubicin
fluorescent properties and probably accompanied with the loss of its
biological activity. Fluorescent properties of APODOX-Nano were
similar to the unmodified APODOX; therefore it was more suited for
the intended use. To evaluate the specificity of apoferritin modified
with antibodies, ELISA-like method was used with the surface of
microtitration plate wells coated by the antigen (goat anti-human IgG
antibodies). To these wells, the nanocarrier was applied. APODOX
without the modification showed 5× lower affinity to the antigen than
APODOX-Nano modified gold and targeting antibodies (human IgG
antibodies).
Abstract: For the music composer Myriam Marbe the musical
time and memory represent 2 (complementary) phenomena with
conclusive impact on the settlement of new musical ontologies.
Summarizing the most important achievements of the contemporary
techniques of composition, her vision on the microform presented in
The Concert for Daniel Kientzy, saxophone and orchestra transcends
the linear and unidirectional time in favour of a flexible, multivectorial
speech with spiral developments, where the sound substance
is auto(re)generated by analogy with the fundamental processes of
the memory. The conceptual model is of an archetypal essence, the
music composer being concerned with identifying the mechanisms of
the creation process, especially of those specific to the collective
creation (of oral tradition). Hence the spontaneity of expression,
improvisation tint, free rhythm, micro-interval intonation, coloristictimbral
universe dominated by multiphonics and unique sound
effects, hence the atmosphere of ritual, however purged by the
primary connotations and reprojected into a wonderful spectacular
space. The Concert is a work of artistic maturity and enforces respect,
among others, by the timbral diversity of the three species of
saxophone required by the music composer (baritone, sopranino and
alt), in Part III Daniel Kientzy shows the performance of playing two
saxophones concomitantly. The score of the music composer Myriam
Marbe contains a deeply spiritualized music, full or archetypal
symbols, a music whose drama suggests a real cinematographic
movement.
Abstract: This paper examines the system protection for cyber-physical
systems (CPS). CPS are particularly characterized by their
networking system components. This means they are able to adapt to
the needs of their users and its environment. With this ability, CPS
have new, specific requirements on the protection against anti-counterfeiting,
know-how loss and manipulation. They increase the
requirements on system protection because piracy attacks can be
more diverse, for example because of an increasing number of
interfaces or through the networking abilities. The new requirements
were identified and in a next step matched with existing protective
measures. Due to the found gap the development of new protection
measures has to be forced to close this gap. Moreover a comparison
of the effectiveness between selected measures was realized and the
first results are presented in this paper.
Abstract: Thousands of organisations store important and
confidential information related to them, their customers, and their
business partners in databases all across the world. The stored data
ranges from less sensitive (e.g. first name, last name, date of birth) to
more sensitive data (e.g. password, pin code, and credit card
information). Losing data, disclosing confidential information or
even changing the value of data are the severe damages that
Structured Query Language injection (SQLi) attack can cause on a
given database. It is a code injection technique where malicious SQL
statements are inserted into a given SQL database by simply using a
web browser. In this paper, we propose an effective pattern
recognition neural network model for detection and classification of
SQLi attacks. The proposed model is built from three main elements
of: a Uniform Resource Locator (URL) generator in order to generate
thousands of malicious and benign URLs, a URL classifier in order
to: 1) classify each generated URL to either a benign URL or a
malicious URL and 2) classify the malicious URLs into different
SQLi attack categories, and a NN model in order to: 1) detect either a
given URL is a malicious URL or a benign URL and 2) identify the
type of SQLi attack for each malicious URL. The model is first
trained and then evaluated by employing thousands of benign and
malicious URLs. The results of the experiments are presented in
order to demonstrate the effectiveness of the proposed approach.
Abstract: In this study, firstly democratic thoughts which
directly or indirectly affect economic development and/or the
interaction between authoritarian regimes and the economic
development and the direction and channels of this interaction were
studied and then the study tried to determine how democracy affects
economic development. It was concluded that the positive
contributions of democracy to economic development were more
determinant than the effects that were either negative or restrictive in
terms of development. When compared to autocracy, since
democracy is more successful in managing social conflicts, ensuring
political stability and preventing social disasters such as famine, it
contributes more to economic development. Democracy also
facilitates delegation of authority, provides a stable investment
environment and accelerates mobilization of resources in accordance
with economic growth/development. Democracy leads to an increase
in human capital accumulation and increases the growth rate through
reducing income inequality. It can be said that democratic regimes
are the most appropriate ones in terms of increasing economic
performance and supporting economic development through their
strong institutional structures and the assurance they will ensure in
property rights.
Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: Quantitative radiobiological models can be used to
assess the optimum clinical outcome from sophisticated therapeutic
modalities by calculating tumor control probability (TCP) and normal
tissue complication probability (NTCP). In this study two 3D-CRT
and an IMRT treatment plans were developed with an initial
prescription dose of 60 Gy in 2 Gy/fraction to prostate. Sensitivity of
TCP and Complication free tumor control probability (P+) to the
different values of α/β ratio was investigated for various prescription
doses planned to be delivered in either a fixed number of fractions (I)
or in a fixed dose per fraction (II) in each of the three different
treatment plans. High dose/fraction and high α/β value result in
comparatively smaller P+ and IMRT plans resulted in the highest P+,
mainly due to the decrease in NTCP. If α/β is lower than expected,
better tumor control can be achieved by increasing dose/fraction but
decreasing the number of fractions.
Abstract: Microscopic simulation tool kits allow for
consideration of the two processes of railway operations and the
previous timetable production. Block occupation conflicts on both
process levels are often solved by using defined train priorities. These
conflict resolutions (dispatching decisions) generate reactionary
delays to the involved trains. The sum of reactionary delays is
commonly used to evaluate the quality of railway operations, which
describes the timetable robustness. It is either compared to an
acceptable train performance or the delays are appraised
economically by linear monetary functions. It is impossible to
adequately evaluate dispatching decisions without a well-founded
objective function. This paper presents a new approach for the
evaluation of dispatching decisions. The approach uses mode choice
models and considers the behaviour of the end-customers. These
models evaluate the reactionary delays in more detail and consider
other competing modes of transport. The new approach pursues the
coupling of a microscopic model of railway operations with the
macroscopic choice mode model. At first, it will be implemented for
railway operations process but it can also be used for timetable
production. The evaluation considers the possibility for the customer
to interchange to other transport modes. The new approach starts to
look at rail and road, but it can also be extended to air travel. The
result of mode choice models is the modal split. The reactions by the
end-customers have an impact on the revenue of the train operating
companies. Different purposes of travel have different payment
reserves and tolerances towards late running. Aside from changes to
revenues, longer journey times can also generate additional costs.
The costs are either time- or track-specific and arise from required
changes to rolling stock or train crew cycles. Only the variable values
are summarised in the contribution margin, which is the base for the
monetary evaluation of delays. The contribution margin is calculated
for different possible solutions to the same conflict. The conflict
resolution is optimised until the monetary loss becomes minimal. The
iterative process therefore determines an optimum conflict resolution
by monitoring the change to the contribution margin. Furthermore, a
monetary value of each dispatching decision can also be derived.
Abstract: This paper investigates the benefits of deliberately
unbalancing both operation time means (MTs) and unreliability
(failure and repair rates) for non-automated production lines. The
lines were simulated with various line lengths, buffer capacities,
degrees of imbalance and patterns of MT and unreliability imbalance.
Data on two performance measures, namely throughput (TR) and
average buffer level (ABL) were gathered, analyzed and compared to
a balanced line counterpart. A number of conclusions were made
with respect to the ranking of configurations, as well as to the
relationships among the independent design parameters and the
dependent variables. It was found that the best configurations are a
balanced line arrangement and a monotone decreasing MT order,
coupled with either a decreasing or a bowl unreliability configuration,
with the first generally resulting in a reduced TR and the second
leading to a lower ABL than those of a balanced line.
Abstract: Non contact evaluation of the thickness of paint
coatings can be attempted by different destructive and nondestructive
methods such as cross-section microscopy, gravimetric mass
measurement, magnetic gauges, Eddy current, ultrasound or
terahertz. Infrared thermography is a nondestructive and non-invasive
method that can be envisaged as a useful tool to measure the surface
thickness variations by analyzing the temperature response. In this
paper, the thermal quadrupole method for two layered samples heated
up with a pulsed excitation is firstly used. By analyzing the thermal
responses as a function of thermal properties and thicknesses of both
layers, optimal parameters for the excitation source can be identified.
Simulations show that a pulsed excitation with duration of ten
milliseconds allows obtaining a substrate-independent thermal
response. Based on this result, an experimental setup consisting of a
near-infrared laser diode and an Infrared camera was next used to
evaluate the variation of paint coating thickness between 60 μm and
130 μm on two samples. Results show that the parameters extracted
for thermal images are correlated with the estimated thicknesses by
the Eddy current methods. The laser pulsed thermography is thus an
interesting alternative nondestructive method that can be moreover
used for nonconductive substrates.
Abstract: Availability of different genetic tests after completion
of Human Genome Project increases the physicians’ responsibility to
keep themselves update on the potential implementation of these
genetic tests in their daily practice. However, due to numbers of
barriers, still many of physicians are not either aware of these tests or
are not willing to offer or refer their patients for genetic tests. This
study was conducted an anonymous, cross-sectional, mailed-based
survey to develop a primary data of Malaysian physicians’ level of
knowledge and perception of gene profiling. Questionnaire had 29
questions. Total scores on selected questions were used to assess the
level of knowledge. The highest possible score was 11. Descriptive
statistics, one way ANOVA and chi-squared test was used for
statistical analysis. Sixty three completed questionnaires were
returned by 27 general practitioners (GPs) and 36 medical specialists.
Responders’ age ranges from 24 to 55 years old (mean 30.2 ± 6.4).
About 40% of the participants rated themselves as having poor level
of knowledge in genetics in general whilst 60% believed that they
have fair level of knowledge; however, almost half (46%) of the
respondents felt that they were not knowledgeable about available
genetic tests. A majority (94%) of the responders were not aware of
any lab or company which is offering gene profiling services in
Malaysia. Only 4% of participants were aware of using gene profiling
for detection of dosage of some drugs. Respondents perceived greater
utility of gene profiling for breast cancer (38%) compared to the
colorectal familial cancer (3%). The score of knowledge ranged from
2 to 8 (mean 4.38 ± 1.67). Non- significant differences between score
of knowledge of GPs and specialists were observed, with score of
4.19 and 4.58 respectively. There was no significant association
between any demographic factors and level of knowledge. However,
those who graduated between years 2001 to 2005 had higher level of
knowledge. Overall, 83% of participants showed relatively high level
of perception on value of gene profiling to detect patient’s risk of
disease. However, low perception was observed for both statements
of using gene profiling for general population in order to alter their
lifestyle (25%) as well as having the full sequence of a patient
genome for the purpose of determining a patient’s best match for
treatment (18%). The lack of clinical guidelines, limited provider
knowledge and awareness, lack of time and resources to educate
patients, lack of evidence-based clinical information and cost of tests
were the most barriers of ordering gene profiling mentioned by
physicians. In conclusion Malaysian physicians who participate in
this study had mediocre level of knowledge and awareness in gene
profiling. The low exposure to the genetic questions and problems
might be a key predictor of lack of awareness and knowledge on
available genetic tests. Educational and training workshop might be useful in helping Malaysian physicians incorporate genetic profiling
into practice for eligible patients.
Abstract: This paper is concerned with knowledge representation
and extraction of fuzzy if-then rules using Interval Type-2
Context-based Fuzzy C-Means clustering (IT2-CFCM) with the aid of
fuzzy granulation. This proposed clustering algorithm is based on
information granulation in the form of IT2 based Fuzzy C-Means
(IT2-FCM) clustering and estimates the cluster centers by preserving
the homogeneity between the clustered patterns from the IT2 contexts
produced in the output space. Furthermore, we can obtain the
automatic knowledge representation in the design of Radial Basis
Function Networks (RBFN), Linguistic Model (LM), and Adaptive
Neuro-Fuzzy Networks (ANFN) from the numerical input-output data
pairs. We shall focus on a design of ANFN in this paper. The
experimental results on an estimation problem of energy performance
reveal that the proposed method showed a good knowledge
representation and performance in comparison with the previous
works.
Abstract: Microalgae Meyerella planktonica is a potential
biofuel source because it can grow in bulk in either autotrophic or
heterotrophic condition. However, the quantitative growth of this
algal type is still low as it tends to precipitates on the bottom.
Besides, the lipid concentration is still low when grown in
autotrophic condition. In contrast, heterotrophic condition can
enhance the lipid concentration. The combination of autotrophic
condition and agitation treatment was conducted to increase the
density of the culture. On the other hand, a heterotrophic condition
was set up to raise the lipid production. A two-stage experiment
was applied to increase the density at the first step and to increase
the lipid concentration in the next step. The autotrophic condition
resulted higher density but lower lipid concentration compared to
heterotrophic one. The agitation treatment produced higher density
in both autotrophic and heterotrophic conditions. The two-stage
experiment managed to enhance the density during the autotrophic
stage and the lipid concentration during the heterotrophic stage.
The highest yield was performed by using 0.4% v/v glycerol as a
carbon source (2.9±0.016 x 10^6 cells w/w) attained 7 days after the
heterotrophic stage began. The lipid concentration was stable
starting from day 7.