Abstract: It is known that the heart interacts with and adapts to its venous and arterial loading conditions. Various experimental studies and modeling approaches have been developed to investigate the underlying mechanisms. This paper presents a model of the left ventricle derived based on nonlinear stress-length myocardial characteristics integrated over truncated ellipsoidal geometry, and second-order dynamic mechanism for the excitation-contraction coupling system. The results of the model presented here describe the effects of the viscoelastic damping element of the electromechanical coupling system on the hemodynamic response. Different heart rates are considered to study the pacing effects on the performance of the left-ventricle against constant preload and afterload conditions under various damping conditions. The results indicate that the pacing process of the left ventricle has to take into account, among other things, the viscoelastic damping conditions of the myofilament excitation-contraction process. The effects of left ventricular dimensions on the hemdynamic response have been examined. These effects are found to be different at different viscoelastic and pacing conditions.
Abstract: Sustainability in rural production system can only be achieved if it can suitably satisfy the local requirement as well as the outside demand with the changing time. With the increased pressure from the food sector in a globalised world, the agrarian economy
needs to re-organise its cultivable land system to be compatible with new management practices as well as the multiple needs of various stakeholders and the changing resource scenario. An attempt has been made to transform this problem into a multi-objective decisionmaking problem considering various objectives, resource constraints and conditional constraints. An interactive fuzzy multi-objective
programming approach has been used for such a purpose taking a
case study in Indian context to demonstrate the validity of the method.
Abstract: Deployment of pneumatic muscles in various
industrial applications is still in its early days, considering the relative
newness of these components. The field of robotics holds particular
future potential for pneumatic muscles, especially in view of their
specific behaviour known as compliance. The paper presents and
discusses an innovative constructive solution for a gripper system
mountable on an industrial robot, based on actuation by a linear
pneumatic muscle and transmission of motion by gear and rack
mechanism. The structural, operational and constructive models of
the new gripper are presented, along with some of the experimental
results obtained subsequently to the testing of a prototype. Further
presented are two control variants of the gripper system, one by
means of a 3/2-way fast-switching solenoid valve, the other by means
of a proportional pressure regulator. Advantages and disadvantages
are discussed for both variants.
Abstract: Soil microbial activity is adversely affected by pollutants such as heavy metals, antibiotics and pesticides. Organic amendments including sewage sludge, municipal compost and vermicompost are recently used to improve soil structure and fertility. But, these materials contain heavy metals including Pb, Cd, Zn, Ni and Cu that are toxic to soil microorganisms and may lead to occurrence of more tolerant microbes. Among these, Pb is the most abundant and has more negative effect on soil microbial ecology. In this study, Pb levels of 0, 100, 200, 300, 400 and 500 mg Pb [as Pb(NO3)2] per kg soil were added to the pots containing 2 kg of a loamy soil and incubated for 6 months at 25°C with soil moisture of - 0.3 MPa. Dehydrogenase activity of soil as a measure of microbial activity was determined on 15, 30, 90 and 180 days after incubation. Triphenyl tetrazolium chloride (TTC) was used as an electron acceptor in this assay. PICTs (IC50 values) were calculated for each Pb level and incubation time. Soil microbial activity was decreased by increasing Pb level during 30 days of incubation but the induced tolerance appeared on day 90 and thereafter. During 90 to 180 days of incubation, the PICT was gradually developed by increasing Pb level up to 200 mg kg-1, but the rate of enhancement was steeper at higher concentrations.
Abstract: In this paper we present high performance
dynamically allocated multi-queue (DAMQ) buffer schemes for fault
tolerance systems on chip applications that require an interconnection
network. Two virtual channels shared the same buffer space. Fault
tolerant mechanisms for interconnection networks are becoming a
critical design issue for large massively parallel computers. It is also
important to high performance SoCs as the system complexity keeps
increasing rapidly. On the message switching layer, we make
improvement to boost system performance when there are faults
involved in the components communication. The proposed scheme is
when a node or a physical channel is deemed as faulty, the previous
hop node will terminate the buffer occupancy of messages destined
to the failed link. The buffer usage decisions are made at switching
layer without interactions with higher abstract layer, thus buffer
space will be released to messages destined to other healthy nodes
quickly. Therefore, the buffer space will be efficiently used in case
fault occurs at some nodes.
Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: Tumour suppressors are key participants in the
prevention of cancer. Regulation of their expression through
miRNAs is important for comprehensive translation inhibition of
tumour suppressors and elucidation of carcinogenesis mechanisms.
We studies the possibility of 1521 miRNAs to bind with 873 mRNAs
of human tumour suppressors using RNAHybrid 2.1 and ERNAhybrid
programmes. Only 978 miRNAs were found to be
translational regulators of 812 mRNAs, and 61 mRNAs did not have
any miRNA binding sites. Additionally, 45.9% of all miRNA binding
sites were located in coding sequences (CDSs), 33.8% were located
in 3' untranslated region (UTR), and 20.3% were located in the
5'UTR. MiRNAs binding with more than 50 target mRNAs and
mRNAs binding with several miRNAs were selected. Hsa-miR-5096
had 15 perfectly complementary binding sites with mRNAs of 14
tumour suppressors. These newly indentified miRNA binding sites
can be used in the development of medicines (anti-sense therapies)
for cancer treatment.
Abstract: Location-based services (LBS) exploit the known
location of a user to provide services dependent on their geographic
context and personalized needs [1].
The development and arrival of broadband mobile data networks
supported with mobile terminals equipped with new location
technologies like GPS have finally created opportunities for
implementation of LBS applications. But, from the other side,
collecting location information data in general raises privacy
concerns.
This paper presents results from two surveys of LBS acceptance in
Croatia. The first survey was administered on 181 students, and the
second extended survey involved pattern of 180 Croatian citizens.
We developed questionnaire which consists of descriptions of 15
different applications with scale which measures perceptions and
attitudes of users towards these applications.
We report the results to identify potential commercial applications
for LBS in B2C segment. Our findings suggest that some types of
applications like emergency&safety services and navigation have
significantly higher rate of acceptance than other types.
Abstract: In the present Jordan hotels scenario, service quality is
a vital competitive policy to keep customer support and build great
base. Hotels are trying to win customer loyalty by providing enhanced
quality services. This paper attempts to examine the impact of tourism
service quality dimension in the Jordanian five star hotels. A total of
322 surveys were administrated to tourists who were staying at three
branches Marriott hotel in Jordan. The results show that dimensions of
service quality such as empathy, reliability, responsiveness and
tangibility significantly predict customer loyalty. Specifically, among
the dimension of tourism service quality, the most significant predictor
of customer loyalty is tangibility. This paper implies that five star
hotels in Jordan should also come forward and try their best to present
better tourism service quality to win back their customers- loyalty.
Abstract: In this paper, the bond strength of thermal spray
coatings in high speed shafts has been studied. The metallurgical and
mechanical studies has been made on the coated samples and shaft
using optical microscopy, scanning electron microscopy (SEM).
Abstract: The present paper develops and validates a numerical procedure for the calculation of turbulent combustive flow in converging and diverging ducts and throuh simulation of the heat transfer processes, the amount of production and spread of Nox pollutant has been measured. A marching integration solution procedure employing the TDMA is used to solve the discretized equations. The turbulence model is the Prandtl Mixing Length method. Modeling the combustion process is done by the use of Arrhenius and Eddy Dissipation method. Thermal mechanism has been utilized for modeling the process of forming the nitrogen oxides. Finite difference method and Genmix numerical code are used for numerical solution of equations. Our results indicate the important influence of the limiting diverging angle of diffuser on the coefficient of recovering of pressure. Moreover, due to the intense dependence of Nox pollutant to the maximum temperature in the domain with this feature, the Nox pollutant amount is also in maximum level.
Abstract: From past many decades human beings are suffering
from plethora of natural disasters. Occurrence of disasters is a
frequent process; it changes conceptual myths as more and more
advancement are made. Although we are living in technological era
but in developing countries like Pakistan disasters are shaped by
socially constructed roles. The need is to understand the most
vulnerable group of society i.e. females; their issues are complex in
nature because of undermined gender status in the society. There is a
need to identify maximum issues regarding females and to enhance
the achievement of millennium development goals (MDGs). Gender
issues are of great concern all around the globe including Pakistan.
Here female visibility in society is low, and also during disasters, the
failure to understand the reality that concentrates on double burden
including productive and reproductive care. Women have to
contribute a lot in society so we need to make them more disaster
resilient. For this non-structural measures like awareness, trainings
and education must be carried out. In rural and in urban settings in
any disaster like earthquake or flood, elements like gender
perspective, their age, physical health, demographic issues contribute
towards vulnerability. In Pakistan the gender issues in disasters were
of less concern before 2005 earthquake and 2010 floods. Significant
achievements are made after 2010 floods when gender and child cell
was created to provide all facilities to women and girls. The aim of
the study is to highlight all necessary facilities in a disaster to build
coping mechanism in females from basic rights till advance level
including education.
Abstract: We report the results of an lattice Boltzmann
simulation of magnetohydrodynamic damping of sidewall convection
in a rectangular enclosure filled with a porous medium. In particular
we investigate the suppression of convection when a steady magnetic
field is applied in the vertical direction. The left and right vertical
walls of the cavity are kept at constant but different temperatures
while both the top and bottom horizontal walls are insulated. The
effects of the controlling parameters involved in the heat transfer and
hydrodynamic characteristics are studied in detail. The heat and mass
transfer mechanisms and the flow characteristics inside the enclosure
depended strongly on the strength of the magnetic field and Darcy
number. The average Nusselt number decreases with rising values of
the Hartmann number while this increases with increasing values of
the Darcy number.
Abstract: Trust is essential for further and wider acceptance of
contemporary e-services. It was first addressed almost thirty years
ago in Trusted Computer System Evaluation Criteria standard by
the US DoD. But this and other proposed approaches of that
period were actually solving security. Roughly some ten years ago,
methodologies followed that addressed trust phenomenon at its core,
and they were based on Bayesian statistics and its derivatives, while
some approaches were based on game theory. However, trust is a
manifestation of judgment and reasoning processes. It has to be dealt
with in accordance with this fact and adequately supported in cyber
environment. On the basis of the results in the field of psychology
and our own findings, a methodology called qualitative algebra has
been developed, which deals with so far overlooked elements of trust
phenomenon. It complements existing methodologies and provides a
basis for a practical technical solution that supports management of
trust in contemporary computing environments. Such solution is also
presented at the end of this paper.
Abstract: In this paper a novel method for multiple one dimensional real valued sinusoidal signal frequency estimation in the presence of additive Gaussian noise is postulated. A computationally simple frequency estimation method with efficient statistical performance is attractive in many array signal processing applications. The prime focus of this paper is to combine the subspace-based technique and a simple peak search approach. This paper presents a variant of the Propagator Method (PM), where a collaborative approach of SUMWE and Propagator method is applied in order to estimate the multiple real valued sine wave frequencies. A new data model is proposed, which gives the dimension of the signal subspace is equal to the number of frequencies present in the observation. But, the signal subspace dimension is twice the number of frequencies in the conventional MUSIC method for estimating frequencies of real-valued sinusoidal signal. The statistical analysis of the proposed method is studied, and the explicit expression of asymptotic (large-sample) mean-squared-error (MSE) or variance of the estimation error is derived. The performance of the method is demonstrated, and the theoretical analysis is substantiated through numerical examples. The proposed method can achieve sustainable high estimation accuracy and frequency resolution at a lower SNR, which is verified by simulation by comparing with conventional MUSIC, ESPRIT and Propagator Method.
Abstract: A water surface slope limiting scheme is tested and
compared with the water depth slope limiter for the solution of one
dimensional shallow water equations with bottom slope source term.
Numerical schemes based on the total variation diminishing Runge-
Kutta discontinuous Galerkin finite element method with slope
limiter schemes based on water surface slope and water depth are
used to solve one-dimensional shallow water equations. For each
slope limiter, three different Riemann solvers based on HLL, LF, and
Roe flux functions are used. The proposed water surface based slope
limiter scheme is easy to implement and shows better conservation
property compared to the slope limiter based on water depth. Of the
three flux functions, the Roe approximation provides the best results
while the LF function proves to be least suitable when used with
either slope limiter scheme.
Abstract: Renewable water resources are crucial production
variables in arid and semi-arid regions where intensive agriculture is
practiced to meet ever-increasing demand for food and fiber. This is
crucial for the Dez and Moghan command areas where water delivery
problems and adverse environmental issues are widespread. This
paper aims to identify major problems areas using on-farm surveys of
200 farmers, agricultural extensionists and water suppliers which was
complemented by secondary data and field observations during 2010-
2011 cultivating season. The SPSS package was used to analyze and
synthesis data. Results indicated inappropriate canal operations in
both schemes, though there was no unanimity about the underlying
causes. Inequitable and inflexible distribution was found to be rooted
in deficient hydraulic structures particularly in the main and
secondary canals. The inadequacy and inflexibility of water
scheduling regime was the underlying causes of recurring pest and
disease spread which often led to the decline of crop yield and
quality, although these were not disputed, the water suppliers were
not prepared to link with the deficiencies in the operation of the main
and secondary canals. They rather attributed these to the prevailing
salinity; alkalinity, water table fluctuations and leaching of the
valuable agro-chemical inputs from the plants- route zone with farreaching
consequences. Examples of these include the pollution of
ground and surface resources due to over-irrigation at the farm level
which falls under the growers- own responsibility. Poor irrigation
efficiency and adverse environmental problems were attributed to
deficient and outdated farming practices that were in turn rooted in
poor extension programs and irrational water charges.
Abstract: A CFD study on heat flux reduction in hypersonic flow with opposing jet has been conducted. Flowfield parameters, reattachment point position, surface pressure distributions and heat flux distributions are obtained and validated with experiments. The physical mechanism of heat reduction has been analyzed. When the opposing jet blows, the freestream is blocked off, flows to the edges and not interacts with the surface to form aerodynamic heating. At the same time, the jet flows back to form cool recirculation region, which reduces the difference in temperature between the surface and the nearby gas, and then reduces the heat flux. As the pressure ratio increases, the interface between jet and freestream is gradually pushed away from the surface. Larger the total pressure ratio is, lower the heat flux is. To study the effect of the intensity of opposing jet more reasonably, a new parameter RPA has been introduced by combining the flux and the total pressure ratio. The study shows that the same shock wave position and total heat load can be obtained with the same RPA with different fluxes and the total pressures, which means the new parameter could stand for the intensity of opposing jet and could be used to analyze the influence of opposing jet on flow field and aerodynamic heating.
Abstract: Development, calibration and validation of a threedimensional
model of the Legform impactor for pedestrian crash with
bumper are presented. Lower limb injury is becoming an increasingly
important concern in vehicle safety for both occupants and
pedestrians. In order to prevent lower extremity injuries to a
pedestrian when struck by a car, it is important to elucidate the
loadings from car front structures on the lower extremities and the
injury mechanism caused by these loadings. An impact test
procedure with a legform addressing lower limb injuries in car
pedestrian accidents has been proposed by EEVC/WG17. In this
study a modified legform impactor is introduced and validated
against EEVC/WG17 criteria. The finite element model of this
legform is developed using LS-DYNA software. Total mass of
legform impactor is 13.4 kg.Technical specifications including the
mass and location of the center of gravity and moment of inertia
about a horizontal axis through the respective centre of gravity in
femur and tibia are determined. The obtained results of legform
impactor static and dynamic tests are as specified in the
EEVC/WG17.
Abstract: Several different cements have been tested to evaluate
their potential to leach calcium, chromium and aluminum ions in soft
water environment. The research allows comparing some different
cements in order to the potential risk of water contamination. This
can be done only in the same environment. To reach the results in
reasonable short time intervals and to make heavy metals
measurements with high accuracy, demineralized water was used. In
this case the conditions of experiments are far away from the water
supply practice, but short time experiments and measurably high
concentrations of elements in the water solution are an important
advantage. Moreover leaching mechanisms can be recognized, our
experiments reported here refer to this kind of cements evaluation.