Abstract: The paper attempts to elucidate the columnar structure
of the cortex by answering the following questions. (1) Why the
cortical neurons with similar interests tend to be vertically arrayed
forming what is known as cortical columns? (2) How to describe the
cortex as a whole in concise mathematical terms? (3) How to design
efficient digital models of the cortex?
Abstract: The present study is aim to prepare and evaluate the selfnanoemulsifying drug delivery (SNEDDS) system of a poorly water soluble drug valsartan in order to achieve a better dissolution rate which would further help in enhancing oral bioavailability. The present research work describes a SNEDDS of valsartan using labrafil M 1944 CS, Tween 80 and Transcutol HP. The pseudoternary phase diagrams with presence and absence of drug were plotted to check for the emulsification range and also to evaluate the effect of valsartan on the emulsification behavior of the phases. The mixtures consisting of oil (labrafil M 1944 CS) with surfactant (tween 80), co-surfactant (Transcutol HP) were found to be optimum formulations. Prepared formulations were evaluated for its particle size distribution, nanoemulsifying properties, robustness to dilution, self emulsication time, turbidity measurement, drug content and invitro dissolution. The optimized formulations are further evaluated for heating cooling cycle, centrifugation studies, freeze thaw cycling, particle size distribution and zeta potential were carried out to confirm the stability of the formed SNEDDS formulations. The prepared formulation revealed t a significant improvement in terms of the drug solubility as compared with marketed tablet and pure drug.
Abstract: In this work, grinding or microcutting tools in the form of pellets were manufactured using a bounded alumina abrasive grains. The bound used is a vitreous material containing quartz feldspars, kaolinite and a quantity of hematite. The pellets were used in glass grinding process to replace the free abrasive grains lapping process. The study of the elaborated pellets were done to define their effectiveness in the grinding process and to optimize the influence of the pellets elaboration parameters. The obtained results show the existence of an optimal combination of the pellets elaboration parameters for each glass grinding phase (coarse to fine grinding). The final roughness (rms) reached by the elaborated pellets on a BK7 glass surface was about 0.392 μm.
Abstract: An unsupervised classification algorithm is derived
by modeling observed data as a mixture of several mutually
exclusive classes that are each described by linear combinations of
independent non-Gaussian densities. The algorithm estimates the
data density in each class by using parametric nonlinear functions
that fit to the non-Gaussian structure of the data. This improves
classification accuracy compared with standard Gaussian mixture
models. When applied to textures, the algorithm can learn basis
functions for images that capture the statistically significant structure
intrinsic in the images. We apply this technique to the problem of
unsupervised texture classification and segmentation.
Abstract: The automatic discrimination of seismic signals is an important practical goal for the earth-science observatories due to the large amount of information that they receive continuously. An essential discrimination task is to allocate the incoming signal to a group associated with the kind of physical phenomena producing it. In this paper, we present new techniques for seismic signals classification: local, regional and global discrimination. These techniques were tested on seismic signals from the data base of the National Geophysical Institute of the Centre National pour la Recherche Scientifique et Technique (Morocco) by using the Moroccan software for seismic signals analysis.
Abstract: Intradiscal and intervertebral pressure transducers
were developed. They were used to map the pressures in the nucleus
and within the annulus of the human spinal segments. Their stressrelaxation
were recorded over a period of time for nucleus
pressure, applied load, and peripherial strain against time. The
results show that for normal discs, pressures in the nucleus are
viscoelastic in nature with the applied compressive load.
Mechanical strains which develop around the periphery of the
vertebral body are also viscoelastic with the applied compressive
load. Applied compressive load against time also shows viscoelastic
behavior. However, annulus does not respond viscoelastically with
the applied load. It showed a linear response to compressive loading.
Abstract: The Kowsar dam supply water for different usages
such as drinking, industrial, agricultural and aquaculture farms
usages and located next to the city of Dehdashat in Kohgiluye and
Boyerahmad province in southern Iran. There are some towns and
villages on the Kowsar dam watersheds, which Dehdasht and Choram
are the most important and populated cities in this area. The study
was undertaken to assess the status of water quality in the urban areas
of the Kowsar dam. A total of 28 water samples were collected from
6 stations on surface water and 1 station from groundwater on the
watershed of the Kowsar dam. All the samples were analyzed for Ni
concentration using standard procedures. The results were compared
with other national and international standards. Among the analyzed
samples, as the maximum value of Nickel (0.01 mg/L) was observed
on the station 2 at the autumn 2010, all the samples analyzed were
within the maximum admissible limits by the United States
Environmental Protection Agency, EU, WHO and the Iranian. In
general results of the present study have shown that a Ni mean value
of station No. 2 with 0.006 mg/L is higher than the other stations. Ni
level of all samples and stations have had normal values and this is an
indication of pollution potential and hazards because of human
activity and waste water of towns in the areas, which can effect on
human health implications in future. This research, therefore,
recommends the government and other responsible authorities to take
suitable improving measures in the Kowsar dam watersheds.
Abstract: Methanol-to-olefins (MTO) coupled with
transformation of coal or natural gas to methanol gives an interesting
and promising way to produce ethylene and propylene. To investigate
solid concentration in gas-solid fluidized bed for methanol-to-olefins
process catalyzed by SAPO-34, a cold model experiment system is
established in this paper. The system comprises a gas distributor in a
300mm internal diameter and 5000mm height acrylic column, the
fiber optic probe system and series of cyclones. The experiments are
carried out at ambient conditions and under different superficial gas
velocity ranging from 0.3930m/s to 0.7860m/s and different initial bed
height ranging from 600mm to 1200mm. The effects of radial
distance, axial distance, superficial gas velocity, initial bed height on
solid concentration in the bed are discussed. The effects of distributor
shape and porosity on solid concentration are also discussed. The
time-averaged solid concentration profiles under different conditions
are obtained.
Abstract: This research aimed to study correlation between
work satisfaction and organization core value of officers in
Waterworks Authority, Bangkean Branch. Sample group of the study
was 112 officers who worked in the Waterworks Authority,
Bangkean Branch. Questionnaires were employed as a research tools,
while, Percentage, Mean, Standard Deviation, T-test, One-way
ANOVA, and Pearson Product Moment Correlation were claimed as
statistics used in this study. Researcher found that overall and
individual aspects of work satisfaction namely, work characteristic,
work progress, and colleagues significantly correlated with
organization core value in aspect of perception in choice of work at
0.5, 0.01, and 0.01 respectively. Also, such aspects were compatible
with income at .05 which indicated the low level of correlation, mid
low correlation respectively at the same direction, same direction,
opposite direction, and same direction, correspondingly.
Abstract: Bicycle usage for exercise, recreation, and commuting
to work in Australia shows that pedal cycling is the fourth most
popular activity with 10.6% increase in participants between 2001
and 2007. As with other means of transport, accident and injury
becomes common although mandatory bicycle helmet wearing has
been introduced. The research aims to develop a face surrogate made
of sandwich of rigid foam and rubber sheets to represent human
facial bone under blunt impact. The facial surrogate will serve as an
important test device for further development of facial-impact
protection for cyclist. A test procedure was developed to simulate the
energy of impact and record data to evaluate the effect of impact on
facial bones. Drop tests were performed to establish a suitable
combination of materials. It was found that the sandwich structure of
rigid extruded-polystyrene foam (density of 40 kg/m3 with a pattern
of 6-mm-holes), Neoprene rubber sponge, and Abrasaflex rubber
backing, had impact characteristics comparable to that of human
facial bone. In particular, the foam thickness of 30 mm and 25 mm
was found suitable to represent human zygoma (cheekbone) and
maxilla (upper-jaw bone), respectively.
Abstract: In the present Jordan hotels scenario, service quality is
a vital competitive policy to keep customer support and build great
base. Hotels are trying to win customer loyalty by providing enhanced
quality services. This paper attempts to examine the impact of tourism
service quality dimension in the Jordanian five star hotels. A total of
322 surveys were administrated to tourists who were staying at three
branches Marriott hotel in Jordan. The results show that dimensions of
service quality such as empathy, reliability, responsiveness and
tangibility significantly predict customer loyalty. Specifically, among
the dimension of tourism service quality, the most significant predictor
of customer loyalty is tangibility. This paper implies that five star
hotels in Jordan should also come forward and try their best to present
better tourism service quality to win back their customers- loyalty.
Abstract: In this study is presented a general methodology to
predict the performance of a continuous near-critical fluid extraction
process to remove compounds from aqueous solutions using hollow
fiber membrane contactors. A comprehensive 2D mathematical
model was developed to study Porocritical extraction process. The
system studied in this work is a membrane based extractor of ethanol
and acetone from aqueous solutions using near-critical CO2.
Predictions of extraction percentages obtained by simulations have
been compared to the experimental values reported by Bothun et al.
[5]. Simulations of extraction percentage of ethanol and acetone
show an average difference of 9.3% and 6.5% with the experimental
data, respectively. More accurate predictions of the extraction of
acetone could be explained by a better estimation of the transport
properties in the aqueous phase that controls the extraction of this
solute.
Abstract: Recently, it is found that telegraph equation is more suitable than ordinary diffusion equation in modelling reaction diffusion for such branches of sciences. In this paper, a numerical solution for the one-dimensional hyperbolic telegraph equation by using the collocation method using the septic splines is proposed. The scheme works in a similar fashion as finite difference methods. Test problems are used to validate our scheme by calculate L2-norm and L∞-norm. The accuracy of the presented method is demonstrated by two test problems. The numerical results are found to be in good agreement with the exact solutions.
Abstract: This paper argues that a product development exercise
involves in addition to the conventional stages, several decisions
regarding other aspects. These aspects should be addressed
simultaneously in order to develop a product that responds to the
customer needs and that helps realize objectives of the stakeholders
in terms of profitability, market share and the like. We present a
framework that encompasses these different development
dimensions. The framework shows that a product development
methodology such as the Quality Function Deployment (QFD) is the
basic tool which allows definition of the target specifications of a
new product. Creativity is the first dimension that enables the
development exercise to live and end successfully. A number of
group processes need to be followed by the development team in
order to ensure enough creativity and innovation. Secondly,
packaging is considered to be an important extension of the product.
Branding strategies, quality and standardization requirements,
identification technologies, design technologies, production
technologies and costing and pricing are also integral parts to the
development exercise. These dimensions constitute the proposed
framework. The paper also presents a mathematical model used to
calculate the design targets based on the target costing principle. The
framework is used to study a case of a new product development in
the telecommunications services sector.
Abstract: This paper discusses a new, systematic approach to
the synthesis of a NP-hard class of non-regenerative Boolean
networks, described by FON[FOFF]={mi}[{Mi}], where for every
mj[Mj]∈{mi}[{Mi}], there exists another mk[Mk]∈{mi}[{Mi}], such
that their Hamming distance HD(mj, mk)=HD(Mj, Mk)=O(n), (where
'n' represents the number of distinct primary inputs). The method
automatically ensures exact minimization for certain important selfdual
functions with 2n-1 points in its one-set. The elements meant for
grouping are determined from a newly proposed weighted incidence
matrix. Then the binary value corresponding to the candidate pair is
correlated with the proposed binary value matrix to enable direct
synthesis. We recommend algebraic factorization operations as a post
processing step to enable reduction in literal count. The algorithm
can be implemented in any high level language and achieves best
cost optimization for the problem dealt with, irrespective of the
number of inputs. For other cases, the method is iterated to
subsequently reduce it to a problem of O(n-1), O(n-2),.... and then
solved. In addition, it leads to optimal results for problems exhibiting
higher degree of adjacency, with a different interpretation of the
heuristic, and the results are comparable with other methods.
In terms of literal cost, at the technology independent stage, the
circuits synthesized using our algorithm enabled net savings over
AOI (AND-OR-Invert) logic, AND-EXOR logic (EXOR Sum-of-
Products or ESOP forms) and AND-OR-EXOR logic by 45.57%,
41.78% and 41.78% respectively for the various problems.
Circuit level simulations were performed for a wide variety of
case studies at 3.3V and 2.5V supply to validate the performance of
the proposed method and the quality of the resulting synthesized
circuits at two different voltage corners. Power estimation was
carried out for a 0.35micron TSMC CMOS process technology. In
comparison with AOI logic, the proposed method enabled mean
savings in power by 42.46%. With respect to AND-EXOR logic, the
proposed method yielded power savings to the tune of 31.88%, while
in comparison with AND-OR-EXOR level networks; average power
savings of 33.23% was obtained.
Abstract: In the present research, a finite element model is
presented to study the geometrical and material nonlinear behavior of
reinforced concrete plane frames considering soil-structure
interaction. The nonlinear behaviors of concrete and reinforcing steel
are considered both in compression and tension up to failure. The
model takes account also for the number, diameter, and distribution
of rebar along every cross section. Soil behavior is taken into
consideration using four different models; namely: linear-, nonlinear
Winkler's model, and linear-, nonlinear continuum model. A
computer program (NARC) is specially developed in order to
perform the analysis. The results achieved by the present model show
good agreement with both theoretical and experimental published
literature. The nonlinear behavior of a rectangular frame resting on
soft soil up to failure using the proposed model is introduced for
demonstration.
Abstract: Trust is essential for further and wider acceptance of
contemporary e-services. It was first addressed almost thirty years
ago in Trusted Computer System Evaluation Criteria standard by
the US DoD. But this and other proposed approaches of that
period were actually solving security. Roughly some ten years ago,
methodologies followed that addressed trust phenomenon at its core,
and they were based on Bayesian statistics and its derivatives, while
some approaches were based on game theory. However, trust is a
manifestation of judgment and reasoning processes. It has to be dealt
with in accordance with this fact and adequately supported in cyber
environment. On the basis of the results in the field of psychology
and our own findings, a methodology called qualitative algebra has
been developed, which deals with so far overlooked elements of trust
phenomenon. It complements existing methodologies and provides a
basis for a practical technical solution that supports management of
trust in contemporary computing environments. Such solution is also
presented at the end of this paper.
Abstract: The dynamics of Min proteins plays a center role in
accurate cell division. Although the nucleoids may presumably play
an important role in prokaryotic cell division, there is a lack of
models to account for its participation. In this work, we apply the
lattice Boltzmann method to investigate protein oscillation based on a
mesoscopic model that takes into account the nucleoid-s role. We
found that our numerical results are in reasonably good agreement
with the previous experimental results On comparing with the other
computational models without the presence of nucleoids, the
highlight of our finding is that the local densities of MinD and MinE
on the cytoplasmic membrane increases, especially along the cell
width, when the size of the obstacle increases, leading to a more
distinct cap-like structure at the poles. This feature indicated the
realistic pattern and reflected the combination of Min protein
dynamics and nucleoid-s role.
Abstract: Development, calibration and validation of a threedimensional
model of the Legform impactor for pedestrian crash with
bumper are presented. Lower limb injury is becoming an increasingly
important concern in vehicle safety for both occupants and
pedestrians. In order to prevent lower extremity injuries to a
pedestrian when struck by a car, it is important to elucidate the
loadings from car front structures on the lower extremities and the
injury mechanism caused by these loadings. An impact test
procedure with a legform addressing lower limb injuries in car
pedestrian accidents has been proposed by EEVC/WG17. In this
study a modified legform impactor is introduced and validated
against EEVC/WG17 criteria. The finite element model of this
legform is developed using LS-DYNA software. Total mass of
legform impactor is 13.4 kg.Technical specifications including the
mass and location of the center of gravity and moment of inertia
about a horizontal axis through the respective centre of gravity in
femur and tibia are determined. The obtained results of legform
impactor static and dynamic tests are as specified in the
EEVC/WG17.
Abstract: The nexus between language and culture is so
intertwined and very significant that language is largely seen as a
vehicle for cultural transmission. Culture itself refers to the aggregate
belief system of a people, embellishing its corporate national image
or brand. If we conceive national rebranding as a campaign to
rekindle the patriotic flame in the consciousness of a people towards
its sociocultural imperatives and values, then, Nigerian indigenous
linguistic flame has not been ignited. Consequently, the paper
contends that the current national rebranding policy remains a myth
in the confines of the elitists' intellectual squabble. It however
recommends that the use of our indigenous languages should be
supported by adequate legislation and also propagated by Nollywood
in order to revamp and sustain the people’s interest in their local
languages. Finally, the use of the indigenous Nigerian languages
demonstrates patriotism, an important ingredient for actualizing a
genuine national rebranding.