Abstract: It is known that the heart interacts with and adapts to its venous and arterial loading conditions. Various experimental studies and modeling approaches have been developed to investigate the underlying mechanisms. This paper presents a model of the left ventricle derived based on nonlinear stress-length myocardial characteristics integrated over truncated ellipsoidal geometry, and second-order dynamic mechanism for the excitation-contraction coupling system. The results of the model presented here describe the effects of the viscoelastic damping element of the electromechanical coupling system on the hemodynamic response. Different heart rates are considered to study the pacing effects on the performance of the left-ventricle against constant preload and afterload conditions under various damping conditions. The results indicate that the pacing process of the left ventricle has to take into account, among other things, the viscoelastic damping conditions of the myofilament excitation-contraction process. The effects of left ventricular dimensions on the hemdynamic response have been examined. These effects are found to be different at different viscoelastic and pacing conditions.
Abstract: Deployment of pneumatic muscles in various
industrial applications is still in its early days, considering the relative
newness of these components. The field of robotics holds particular
future potential for pneumatic muscles, especially in view of their
specific behaviour known as compliance. The paper presents and
discusses an innovative constructive solution for a gripper system
mountable on an industrial robot, based on actuation by a linear
pneumatic muscle and transmission of motion by gear and rack
mechanism. The structural, operational and constructive models of
the new gripper are presented, along with some of the experimental
results obtained subsequently to the testing of a prototype. Further
presented are two control variants of the gripper system, one by
means of a 3/2-way fast-switching solenoid valve, the other by means
of a proportional pressure regulator. Advantages and disadvantages
are discussed for both variants.
Abstract: Soil microbial activity is adversely affected by pollutants such as heavy metals, antibiotics and pesticides. Organic amendments including sewage sludge, municipal compost and vermicompost are recently used to improve soil structure and fertility. But, these materials contain heavy metals including Pb, Cd, Zn, Ni and Cu that are toxic to soil microorganisms and may lead to occurrence of more tolerant microbes. Among these, Pb is the most abundant and has more negative effect on soil microbial ecology. In this study, Pb levels of 0, 100, 200, 300, 400 and 500 mg Pb [as Pb(NO3)2] per kg soil were added to the pots containing 2 kg of a loamy soil and incubated for 6 months at 25°C with soil moisture of - 0.3 MPa. Dehydrogenase activity of soil as a measure of microbial activity was determined on 15, 30, 90 and 180 days after incubation. Triphenyl tetrazolium chloride (TTC) was used as an electron acceptor in this assay. PICTs (IC50 values) were calculated for each Pb level and incubation time. Soil microbial activity was decreased by increasing Pb level during 30 days of incubation but the induced tolerance appeared on day 90 and thereafter. During 90 to 180 days of incubation, the PICT was gradually developed by increasing Pb level up to 200 mg kg-1, but the rate of enhancement was steeper at higher concentrations.
Abstract: In this paper we present high performance
dynamically allocated multi-queue (DAMQ) buffer schemes for fault
tolerance systems on chip applications that require an interconnection
network. Two virtual channels shared the same buffer space. Fault
tolerant mechanisms for interconnection networks are becoming a
critical design issue for large massively parallel computers. It is also
important to high performance SoCs as the system complexity keeps
increasing rapidly. On the message switching layer, we make
improvement to boost system performance when there are faults
involved in the components communication. The proposed scheme is
when a node or a physical channel is deemed as faulty, the previous
hop node will terminate the buffer occupancy of messages destined
to the failed link. The buffer usage decisions are made at switching
layer without interactions with higher abstract layer, thus buffer
space will be released to messages destined to other healthy nodes
quickly. Therefore, the buffer space will be efficiently used in case
fault occurs at some nodes.
Abstract: The paper attempts to elucidate the columnar structure
of the cortex by answering the following questions. (1) Why the
cortical neurons with similar interests tend to be vertically arrayed
forming what is known as cortical columns? (2) How to describe the
cortex as a whole in concise mathematical terms? (3) How to design
efficient digital models of the cortex?
Abstract: Collective action can be an effective means for local development as well as important strategy to enhance livelihoods especially among rural people. This article explores the level of collective action among members of Fishermen-s Wives Group (KUNITA) in Malaysia. KUNITA was established by the Malaysian Fishery Development Authority (LKIM) with an objective to increase the socio-economic status of fishermen-s families. The members who are mostly the wives and daughters of fishermen are strongly encouraged by LKIM to venture into entrepreneurship activities. The objective of this research was to see the level of collective action among members in KUNITA groups in the state of Selangor. The finding shows that high level of collective action among KUNITA members is strongly based on volunteerism. However, the level of cooperation among members in the group is relatively low. The findings present significant challenges for the group in maintaining the sustainability of KUNITA organization.
Abstract: In molecular biology, microarray technology is widely and successfully utilized to efficiently measure gene activity. If working with less studied organisms, methods to design custom-made microarray probes are available. One design criterion is to select probes with minimal melting temperature variances thus ensuring similar hybridization properties. If the microarray application focuses on the investigation of metabolic pathways, it is not necessary to cover the whole genome. It is more efficient to cover each metabolic pathway with a limited number of genes. Firstly, an approach is presented which minimizes the overall melting temperature variance of selected probes for all genes of interest. Secondly, the approach is extended to include the additional constraints of covering all pathways with a limited number of genes while minimizing the overall variance. The new optimization problem is solved by a bottom-up programming approach which reduces the complexity to make it computationally feasible. The new method is exemplary applied for the selection of microarray probes in order to cover all fungal secondary metabolite gene clusters for Aspergillus terreus.
Abstract: The project describes the modeling of various
architectures mechatronics specifically morphologies of robots in an educational environment. Each structure developed by students of
pre-school, primary and secondary was created using the concept of
reverse engineering in a constructivist environment, to later be integrated in educational software that promotes the teaching of
educational Robotics in a virtual and economic environment.
Abstract: The automatic discrimination of seismic signals is an important practical goal for the earth-science observatories due to the large amount of information that they receive continuously. An essential discrimination task is to allocate the incoming signal to a group associated with the kind of physical phenomena producing it. In this paper, we present new techniques for seismic signals classification: local, regional and global discrimination. These techniques were tested on seismic signals from the data base of the National Geophysical Institute of the Centre National pour la Recherche Scientifique et Technique (Morocco) by using the Moroccan software for seismic signals analysis.
Abstract: The purpose of Grid computing is to utilize
computational power of idle resources which are distributed in
different areas. Given the grid dynamism and its decentralize
resources, there is a need for an efficient scheduler for scheduling
applications. Since task scheduling includes in the NP-hard problems
various researches have focused on invented algorithms especially
the genetic ones. But since genetic is an inherent algorithm which
searches the problem space globally and does not have the efficiency
required for local searching, therefore, its combination with local
searching algorithms can compensate for this shortcomings. The aim
of this paper is to combine the genetic algorithm and GELS (GAGELS)
as a method to solve scheduling problem by which
simultaneously pay attention to two factors of time and number of
missed tasks. Results show that the proposed algorithm can decrease
makespan while minimizing the number of missed tasks compared
with the traditional methods.
Abstract: Tumour suppressors are key participants in the
prevention of cancer. Regulation of their expression through
miRNAs is important for comprehensive translation inhibition of
tumour suppressors and elucidation of carcinogenesis mechanisms.
We studies the possibility of 1521 miRNAs to bind with 873 mRNAs
of human tumour suppressors using RNAHybrid 2.1 and ERNAhybrid
programmes. Only 978 miRNAs were found to be
translational regulators of 812 mRNAs, and 61 mRNAs did not have
any miRNA binding sites. Additionally, 45.9% of all miRNA binding
sites were located in coding sequences (CDSs), 33.8% were located
in 3' untranslated region (UTR), and 20.3% were located in the
5'UTR. MiRNAs binding with more than 50 target mRNAs and
mRNAs binding with several miRNAs were selected. Hsa-miR-5096
had 15 perfectly complementary binding sites with mRNAs of 14
tumour suppressors. These newly indentified miRNA binding sites
can be used in the development of medicines (anti-sense therapies)
for cancer treatment.
Abstract: Heavy rainfall greatly affects the aerodynamic performance of the aircraft. There are many accidents of aircraft caused by aerodynamic efficiency degradation by heavy rain.
In this Paper we have studied the heavy rain effects on the aerodynamic efficiency of cambered NACA 64-210 and symmetric
NACA 0012 airfoils. Our results show significant increase in drag and decrease in lift. We used preprocessing software gridgen for creation of geometry and mesh, used fluent as solver and techplot as postprocessor. Discrete phase modeling called DPM is used to model the rain particles using two phase flow approach. The rain particles are assumed to be inert.
Both airfoils showed significant decrease in lift and increase in drag in simulated rain environment. The most significant difference between these two airfoils was the NACA 64-210 more sensitivity than NACA 0012 to liquid water content (LWC). We believe that the results showed in this paper will be useful for the designer of the commercial aircrafts and UAVs, and will be helpful for training of the pilots to control the airplanes in heavy rain.
Abstract: In the present Jordan hotels scenario, service quality is
a vital competitive policy to keep customer support and build great
base. Hotels are trying to win customer loyalty by providing enhanced
quality services. This paper attempts to examine the impact of tourism
service quality dimension in the Jordanian five star hotels. A total of
322 surveys were administrated to tourists who were staying at three
branches Marriott hotel in Jordan. The results show that dimensions of
service quality such as empathy, reliability, responsiveness and
tangibility significantly predict customer loyalty. Specifically, among
the dimension of tourism service quality, the most significant predictor
of customer loyalty is tangibility. This paper implies that five star
hotels in Jordan should also come forward and try their best to present
better tourism service quality to win back their customers- loyalty.
Abstract: In this paper, the bond strength of thermal spray
coatings in high speed shafts has been studied. The metallurgical and
mechanical studies has been made on the coated samples and shaft
using optical microscopy, scanning electron microscopy (SEM).
Abstract: The present paper develops and validates a numerical procedure for the calculation of turbulent combustive flow in converging and diverging ducts and throuh simulation of the heat transfer processes, the amount of production and spread of Nox pollutant has been measured. A marching integration solution procedure employing the TDMA is used to solve the discretized equations. The turbulence model is the Prandtl Mixing Length method. Modeling the combustion process is done by the use of Arrhenius and Eddy Dissipation method. Thermal mechanism has been utilized for modeling the process of forming the nitrogen oxides. Finite difference method and Genmix numerical code are used for numerical solution of equations. Our results indicate the important influence of the limiting diverging angle of diffuser on the coefficient of recovering of pressure. Moreover, due to the intense dependence of Nox pollutant to the maximum temperature in the domain with this feature, the Nox pollutant amount is also in maximum level.
Abstract: From past many decades human beings are suffering
from plethora of natural disasters. Occurrence of disasters is a
frequent process; it changes conceptual myths as more and more
advancement are made. Although we are living in technological era
but in developing countries like Pakistan disasters are shaped by
socially constructed roles. The need is to understand the most
vulnerable group of society i.e. females; their issues are complex in
nature because of undermined gender status in the society. There is a
need to identify maximum issues regarding females and to enhance
the achievement of millennium development goals (MDGs). Gender
issues are of great concern all around the globe including Pakistan.
Here female visibility in society is low, and also during disasters, the
failure to understand the reality that concentrates on double burden
including productive and reproductive care. Women have to
contribute a lot in society so we need to make them more disaster
resilient. For this non-structural measures like awareness, trainings
and education must be carried out. In rural and in urban settings in
any disaster like earthquake or flood, elements like gender
perspective, their age, physical health, demographic issues contribute
towards vulnerability. In Pakistan the gender issues in disasters were
of less concern before 2005 earthquake and 2010 floods. Significant
achievements are made after 2010 floods when gender and child cell
was created to provide all facilities to women and girls. The aim of
the study is to highlight all necessary facilities in a disaster to build
coping mechanism in females from basic rights till advance level
including education.
Abstract: We report the results of an lattice Boltzmann
simulation of magnetohydrodynamic damping of sidewall convection
in a rectangular enclosure filled with a porous medium. In particular
we investigate the suppression of convection when a steady magnetic
field is applied in the vertical direction. The left and right vertical
walls of the cavity are kept at constant but different temperatures
while both the top and bottom horizontal walls are insulated. The
effects of the controlling parameters involved in the heat transfer and
hydrodynamic characteristics are studied in detail. The heat and mass
transfer mechanisms and the flow characteristics inside the enclosure
depended strongly on the strength of the magnetic field and Darcy
number. The average Nusselt number decreases with rising values of
the Hartmann number while this increases with increasing values of
the Darcy number.
Abstract: A CFD study on heat flux reduction in hypersonic flow with opposing jet has been conducted. Flowfield parameters, reattachment point position, surface pressure distributions and heat flux distributions are obtained and validated with experiments. The physical mechanism of heat reduction has been analyzed. When the opposing jet blows, the freestream is blocked off, flows to the edges and not interacts with the surface to form aerodynamic heating. At the same time, the jet flows back to form cool recirculation region, which reduces the difference in temperature between the surface and the nearby gas, and then reduces the heat flux. As the pressure ratio increases, the interface between jet and freestream is gradually pushed away from the surface. Larger the total pressure ratio is, lower the heat flux is. To study the effect of the intensity of opposing jet more reasonably, a new parameter RPA has been introduced by combining the flux and the total pressure ratio. The study shows that the same shock wave position and total heat load can be obtained with the same RPA with different fluxes and the total pressures, which means the new parameter could stand for the intensity of opposing jet and could be used to analyze the influence of opposing jet on flow field and aerodynamic heating.
Abstract: Development, calibration and validation of a threedimensional
model of the Legform impactor for pedestrian crash with
bumper are presented. Lower limb injury is becoming an increasingly
important concern in vehicle safety for both occupants and
pedestrians. In order to prevent lower extremity injuries to a
pedestrian when struck by a car, it is important to elucidate the
loadings from car front structures on the lower extremities and the
injury mechanism caused by these loadings. An impact test
procedure with a legform addressing lower limb injuries in car
pedestrian accidents has been proposed by EEVC/WG17. In this
study a modified legform impactor is introduced and validated
against EEVC/WG17 criteria. The finite element model of this
legform is developed using LS-DYNA software. Total mass of
legform impactor is 13.4 kg.Technical specifications including the
mass and location of the center of gravity and moment of inertia
about a horizontal axis through the respective centre of gravity in
femur and tibia are determined. The obtained results of legform
impactor static and dynamic tests are as specified in the
EEVC/WG17.
Abstract: Several different cements have been tested to evaluate
their potential to leach calcium, chromium and aluminum ions in soft
water environment. The research allows comparing some different
cements in order to the potential risk of water contamination. This
can be done only in the same environment. To reach the results in
reasonable short time intervals and to make heavy metals
measurements with high accuracy, demineralized water was used. In
this case the conditions of experiments are far away from the water
supply practice, but short time experiments and measurably high
concentrations of elements in the water solution are an important
advantage. Moreover leaching mechanisms can be recognized, our
experiments reported here refer to this kind of cements evaluation.