Design of a Carbon Silicon Electrode for Iontophoresis Treatment towards Alopecia

This study presents design of a carbon silicon electrode for iontophorsis treatment towards alopecia. The alopecia is a medical description means loss of hair from the body. For solving this problem, the drug need to be delivered into the scalp, therefore, the iontophoresis was chosen to use in this treatment. However, almost common electrodes of iontophoresis device are made with metal material, the electrodes could give patients hurt when they using it, and it is hard to avoid the hair for attaching the hair. For this reason, an electrode is made with silicon material to decrease the hurt from the electrodes, and the carbon material is mixed in it for increasing conductance. The several cones with stainless material on the electrode make the electrode is able to void hair to attach the affected part. According to the results of a vivo-experiment, the carbon silicon electrode showed a good performance and in treatment comfortably.

IVE: Virtual Humans AI Prototyping Toolkit

IVE toolkit has been created for facilitating research,education and development in the ?eld of virtual storytelling andcomputer games. Primarily, the toolkit is intended for modellingaction selection mechanisms of virtual humans, investigating level-of-detail AI techniques for large virtual environments, and for exploringjoint behaviour and role-passing technique (Sec. V). Additionally, thetoolkit can be used as an AI middleware without any changes. Themain facility of IVE is that it serves for prototyping both the AI andvirtual worlds themselves. The purpose of this paper is to describeIVE?s features in general and to present our current work - includingan educational game - on this platform.Keywords? AI middleware, simulation, virtual world.

Encryption Efficiency Analysis and Security Evaluation of RC6 Block Cipher for Digital Images

This paper investigates the encryption efficiency of RC6 block cipher application to digital images, providing a new mathematical measure for encryption efficiency, which we will call the encryption quality instead of visual inspection, The encryption quality of RC6 block cipher is investigated among its several design parameters such as word size, number of rounds, and secret key length and the optimal choices for the best values of such design parameters are given. Also, the security analysis of RC6 block cipher for digital images is investigated from strict cryptographic viewpoint. The security estimations of RC6 block cipher for digital images against brute-force, statistical, and differential attacks are explored. Experiments are made to test the security of RC6 block cipher for digital images against all aforementioned types of attacks. Experiments and results verify and prove that RC6 block cipher is highly secure for real-time image encryption from cryptographic viewpoint. Thorough experimental tests are carried out with detailed analysis, demonstrating the high security of RC6 block cipher algorithm. So, RC6 block cipher can be considered to be a real-time secure symmetric encryption for digital images.

Novel Direct Flux and Torque Control of Optimally Designed 6 Phase Reluctance Machine with Special Current Waveform

In this paper the principle, basic torque theory and design optimisation of a six-phase reluctance dc machine are considered. A trapezoidal phase current waveform for the machine drive is proposed and evaluated to minimise ripple torque. Low cost normal laminated salient-pole rotors with and without slits and chamfered poles are investigated. The six-phase machine is optimised in multi-dimensions by linking the finite-element analysis method directly with an optimisation algorithm; the objective function is to maximise the torque per copper losses of the machine. The armature reaction effect is investigated in detail and found to be severe. The measured and calculated torque performances of a 35 kW optimum designed six-phase reluctance dc machine drive are presented.

Accounting Research from the Globalization Perspective

This paper explores the idea of globalisation and considers accounting-s role in that process in order to develop new spaces for accounting research. That-s why in this paper we are looking for questions not necessary for answers. Adopting an 'alternative' view of accounting it-s related to the fact that we sees accounting as social and evolutionist process, that pays heed to those voices arguing for greater social and environmental justice, and that draws attention to the role of accounting researchers in the process of globalisation. The paper defines globalisation and expands the globalisation and accounting research agenda introducing in this context the harmonization process in accounting. There are the two main systems which are disputing the first stage of being the benchmark: GAAP and IFRS. Each of them has his pluses and minuses on being the selected one. Due to this fact a convergence of the two, joining the advantages and disadvantages of the two should be the solution for an unique international accounting solution. Is this idea realizable, what steps has been made until now, what should be done in the future. The paper is emphasising the role of the cultural differences in the process of imposing of an unique international accounting system by the global organizations..

Design of a Low Cost Motion Data Acquisition Setup for Mechatronic Systems

Motion sensors have been commonly used as a valuable component in mechatronic systems, however, many mechatronic designs and applications that need motion sensors cost enormous amount of money, especially high-tech systems. Design of a software for communication protocol between data acquisition card and motion sensor is another issue that has to be solved. This study presents how to design a low cost motion data acquisition setup consisting of MPU 6050 motion sensor (gyro and accelerometer in 3 axes) and Arduino Mega2560 microcontroller. Design parameters are calibration of the sensor, identification and communication between sensor and data acquisition card, interpretation of data collected by the sensor.

Time-Cost-Quality Trade-off Software by using Simplified Genetic Algorithm for Typical Repetitive Construction Projects

Time-Cost Optimization "TCO" is one of the greatest challenges in construction project planning and control, since the optimization of either time or cost, would usually be at the expense of the other. Since there is a hidden trade-off relationship between project and cost, it might be difficult to predict whether the total cost would increase or decrease as a result of the schedule compression. Recently third dimension in trade-off analysis is taken into consideration that is quality of the projects. Few of the existing algorithms are applied in a case of construction project with threedimensional trade-off analysis, Time-Cost-Quality relationships. The objective of this paper is to presents the development of a practical software system; that named Automatic Multi-objective Typical Construction Resource Optimization System "AMTCROS". This system incorporates the basic concepts of Line Of Balance "LOB" and Critical Path Method "CPM" in a multi-objective Genetic Algorithms "GAs" model. The main objective of this system is to provide a practical support for typical construction planners who need to optimize resource utilization in order to minimize project cost and duration while maximizing its quality simultaneously. The application of these research developments in planning the typical construction projects holds a strong promise to: 1) Increase the efficiency of resource use in typical construction projects; 2) Reduce construction duration period; 3) Minimize construction cost (direct cost plus indirect cost); and 4) Improve the quality of newly construction projects. A general description of the proposed software for the Time-Cost-Quality Trade-Off "TCQTO" is presented. The main inputs and outputs of the proposed software are outlined. The main subroutines and the inference engine of this software are detailed. The complexity analysis of the software is discussed. In addition, the verification, and complexity of the proposed software are proved and tested using a real case study.

Sorption of Nickel by Hypnea Valentiae: Application of Response Surface Methodology

In this work, sorption of nickel from aqueous solution on hypnea valentiae, red macro algae, was investigated. Batch experiments have been carried out to find the effect of various parameters such as pH, temperature, sorbent dosage, metal concentration and contact time on the sorption of nickel using hypnea valentiae. Response surface methodology (RSM) is employed to optimize the process parameters. Based on the central composite design, quadratic model was developed to correlate the process variables to the response. The most influential factor on each experimental design response was identified from the analysis of variance (ANOVA). The optimum conditions for the sorption of nickel were found to be: pH – 5.1, temperature – 36.8oC, sorbent dosage – 5.1 g/L, metal concentration – 100 mg/L and contact time – 30 min. At these optimized conditions the maximum removal of nickel was found to be 91.97%. A coefficient of determination R2 value 0.9548 shows the fitness of response surface methodology in this work.

Temperature Variation Effects on I-V Characteristics of Cu-Phthalocyanine based OFET

In this study we present the effect of elevated temperatures from 300K to 400K on the electrical properties of copper Phthalocyanine (CuPc) based organic field effect transistors (OFET). Thin films of organic semiconductor CuPc (40nm) and semitransparent Al (20nm) were deposited in sequence, by vacuum evaporation on a glass substrate with previously deposited Ag source and drain electrodes with a gap of 40 μm. Under resistive mode of operation, where gate was suspended it was observed that drain current of this organic field effect transistor (OFET) show an increase with temperature. While in grounded gate condition metal (aluminum) – semiconductor (Copper Phthalocyanine) Schottky junction dominated the output characteristics and device showed switching effect from low to high conduction states like Zener diode at higher bias voltages. This threshold voltage for switching effect has been found to be inversely proportional to temperature and shows an abrupt decrease after knee temperature of 360K. Change in dynamic resistance (Rd = dV/dI) with respect to temperature was observed to be -1%/K.

Enhanced Mycophenolic Acid Production by Penicillium brevicompactum with Enzymatically Hydrolyzed Casein

Mycophenolic acid (MPA) is a secondary metabolite produced by Penicillium brevicompactum, which has antibiotic and immunosuppressive properties. In this study, the first, mycophenolic acid was produced in a fermentation process by Penicillium brevicompactum MUCL 19011 in shake flask using a base medium. The maximum MPA production, product yield and productivity of process were 1.379 g/L, 18.6 mg/g glucose and 4.9 mg/L. h, respectively. Also the glucose consumption, biomass and MPA production profiles were investigated during batch cultivation. Obtained results showed that MPA production starts approximately after 180 hours and reaches to a maximum at 280 h. In the next step, the effects of some various concentrations of enzymatically hydrolyzed casein on MPA production were evaluated. Maximum MPA production, product yield and productivity as 3.63 g/L, 49 mg/g glucose and 12.96 mg/L.h, respectively were obtained with using 30 g/L enzymatically hydrolyzed casein in culture medium. These values show an enhanced MPA production, product yield and process productivity pr as 116.8%, 132.8% and 163.2%, respectively.

Changes in Behavior and Learning Ability of Rats Intoxicated with Lead

Measuring the effect of perinatal lead exposure on learning ability of offspring is considered as a sensitive and selective index for providing an early marker for central nervous system damage produced by this toxic metal. A total of 35 Sprague-Dawley adult rats were used to investigate the effect of lead acetate toxicity on behavioral patterns of adult female rats and learning ability of offspring. Rats were allotted into 4 groups, group one received 1g/l lead acetate (n=10), group two received 1.5g/l lead acetate (n=10), group three received 2g/l lead acetate in drinking water (n=10) and control group did not receive lead acetate (n=5) from 8th day of pregnancy till weaning of pups. The obtained results revealed a dose dependent increase in the feeding time, drinking frequency, licking frequency, scratching frequency, licking litters, nest building and retrieving frequencies, while standing time increased significantly in rats treated with 1.5g/l lead acetate than other treated groups and control, on contrary lying time decreased gradually in a dose dependent manner. Moreover, movement activities were higher in rats treated with 1g/l lead acetate than other treated groups and control. Furthermore, time spent in closed arms was significantly lower in rats given 2g/l lead acetate than other treated groups, while, they spent significantly much time spent in open arms than other treated groups which could be attributed to occurrence of adaptation. Furthermore, number of entries in open arms was dose dependent. However, the ratio between open/closed arms revealed a significant decrease in rats treated with 2g/l lead acetate than control group.

Paleoclimate Reconstruction during Pabdeh, Gurpi, Kazhdumi and Gadvan Formations (Cretaceous-Tertiary) Based on Clay Mineral Distribution

Paleoclimate was reconstructed by the clay mineral assemblages of shale units of Pabdeh (Paleocene- Oligocene), Gurpi (Upper Cretaceous), Kazhdumi (Albian-Cenomanian) and Gadvan (Aptian-Neocomian) formations in the Bangestan anticline. To compare with clay minerals assemblages in these formations, selected samples also taken from available formations in drilled wells in Ahvaz, Marun, Karanj, and Parsi oil fields. Collected samples prepared using standard clay mineral methodology. They were treated as normal, glycolated and heated oriented glass slides. Their identification was made on X-Ray diffractographs. Illite % varies from 8 to 36. Illite quantity increased from Pabdeh to Gurpi Formation. This may be due to dominant dry climate. Kaolinite is in range of 12-49%. Its variation style in different formations could be a marker of climate changes from wet to dry which is supported by the lithological changes. Chlorite (4-28%) can also be detected in those samples without any kaolinite. Mixed layer minerals as the mixture of illite-chlorite and illite-vermiculite-montmorillonite are varied from 6 to 36%, decreased during Kazhdumi deposition from the base to the top. This result may be according to decreasing of illite leaching process. Vermiculite was also determined in very less quantity and found in those units without kaolinite. Montmorillonite varies from 8 to 43%, and its presence is due to terrestrial depositional condition. Stratigraphical documents is also supported this idea that clay mineral distribution is a function of the climate changes. It seems, thus, the present results can be indicated a possible procedure for ancient climate changes evaluation.

Asset Management for Educational Buildings in Egypt

In Egypt, the concept of Asset Management (AM) is new; however, the need for applying it has become crucial because deteriorating or losing an asset is unaffordable in a developing country like Egypt. Therefore the current study focuses on educational buildings as one of the most important assets regarding planning, building, operating and maintenance expenditures. The main objective of this study is to develop a SAMF for educational buildings in Egypt. The General Authority for Educational Buildings (GAEB) was chosen as a case study of the current research as it represents the biggest governmental organization responsible for planning, operating and maintaining schools in Egypt. To achieve the research objective, structured interviews were conducted with senior managers of GAEB using a pre designed questionnaire to explore the current practice of AM. Gab analysis technique was applied against best practices compounded from a vast literature review to identify gaps between current practices and the desired one. The previous steps mainly revealed; limited knowledge about strategic asset management, no clear goals, no training, no real risk plan and lack of data, technical and financial resources. Based on the findings, a SAMF for GAEB was introduced and Framework implementation steps and assessment techniques were explained in detail.

Evolutionary Origin of the αC Helix in Integrins

Integrins are a large family of multidomain α/β cell signaling receptors. Some integrins contain an additional inserted I domain, whose earliest expression appears to be with the chordates, since they are observed in the urochordates Ciona intestinalis (vase tunicate) and Halocynthia roretzi (sea pineapple), but not in integrins of earlier diverging species. The domain-s presence is viewed as a hallmark of integrins of higher metazoans, however in vertebrates, there are clearly three structurally-different classes: integrins without I domains, and two groups of integrins with I domains but separable by the presence or absence of an additional αC helix. For example, the αI domains in collagen-binding integrins from Osteichthyes (bony fish) and all higher vertebrates contain the specific αC helix, whereas the αI domains in non-collagen binding integrins from vertebrates and the αI domains from earlier diverging urochordate integrins, i.e. tunicates, do not. Unfortunately, within the early chordates, there is an evolutionary gap due to extinctions between the tunicates and cartilaginous fish. This, coupled with a knowledge gap due to the lack of complete genomic data from surviving species, means that the origin of collagen-binding αC-containing αI domains remains unknown. Here, we analyzed two available genomes from Callorhinchus milii (ghost shark/elephant shark; Chondrichthyes – cartilaginous fish) and Petromyzon marinus (sea lamprey; Agnathostomata), and several available Expression Sequence Tags from two Chondrichthyes species: Raja erinacea (little skate) and Squalus acanthias (dogfish shark); and Eptatretus burgeri (inshore hagfish; Agnathostomata), which evolutionary reside between the urochordates and osteichthyes. In P. marinus, we observed several fragments coding for the αC-containing αI domain, allowing us to shed more light on the evolution of the collagen-binding integrins.

Automation of Fishhooks Objective Measures

Fishing has always been an essential component of the Polynesians- life. Fishhooks, mostly in pearl shell, found during archaeological excavations are the artifacts related to this activity the most numerous. Thanks to them, we try to reconstruct the ancient techniques of resources exploitation, inside the lagoons and offshore. They can also be used as chronological and cultural indicators. The shapes and dimensions of these artifacts allow comparisons and classifications used in both functional approach and chrono-cultural perspective. Hence it is very important for the ethno-archaeologists to dispose of reliable methods and standardized measurement of these artifacts. Such a reliable objective and standardized method have been previously proposed. But this method cannot be envisaged manually because of the very important time required to measure each fishhook manually and the quantity of fishhooks to measure (many hundreds). We propose in this paper a detailed acquisition protocol of fishhooks and an automation of every step of this method. We also provide some experimental results obtained on the fishhooks coming from three archaeological excavations sites.

A Ring Segmented Bus Architecture for Globally Asynchronous Locally Synchronous System

Recently, most digital systems are designed as GALS (Globally Asynchronous Locally Synchronous) systems. Several architectures have been proposed as bus architectures for a GALS system : shared bus, segmented bus, ring bus, and so on. In this study, we propose a ring segmented bus architecture which is a combination of segmented bus and ring bus architecture with the aim of throughput enhancement. In a segmented bus architecture, segments are connected in series. By connecting the segments at the end of the bus and constructing the ring bus, it becomes possible to allocate a channel of the bus bidirectionally. The bus channel is allocated to the shortest path between segments. We consider a metastable operation caused by asynchronous communication between segments and a burst transfer between segments. According to the result of simulation, it is shown that the GALS system designed by the proposed method has the desired operations.

Assessment of Maternal and Embryo-Fetal Toxicity of Copper Oxide Fungicide

The excessive use of agricultural pesticides and the resulting contamination of food and beds of rivers have been a recurring problem nowadays. Some of these substances can cause changes in endocrine balance and impair reproductive function of human and animal population. In the present study, we evaluated the possible effects of the fungicide cuprous copper oxide Sandoz® on pregnant Wistar rats. They received a daily oral administration of 103 or 3.103 mg/kg of the fungicide from the 6th to the 15th day of gestation. On day 21 of gestation, the maternal and fetal toxicity parameters and indices were determined. The administration of cuprous oxide (Copper Sandoz) in Wistar rats, the period of organogenesis, revealed no evidence of maternal toxicity or embryo at the studied doses.

Effect of Cooling Rate on base Metals Recovery from Copper Matte Smelting Slags

Slag sample from copper smelting operation in a water jacket furnace from DRC plant was used. The study intends to determine the effect of cooling in the extraction of base metals. The cooling methods investigated were water quenching, air cooling and furnace cooling. The latter cooling ways were compared to the original as received slag. It was observed that, the cooling rate of the slag affected the leaching of base metals as it changed the phase distribution in the slag and the base metals distribution within the phases. It was also found that fast cooling of slag prevented crystallization and produced an amorphous phase that encloses the base metals. The amorphous slags from the slag dumps were more leachable in acidic medium (HNO3) which leached 46%Cu, 95% Co, 85% Zn, 92% Pb and 79% Fe with no selectivity at pH0, than in basic medium (NH4OH). The leachability was vice versa for the modified slags by quenching in water which leached 89%Cu with a high selectivity as metal extractions are less than 1% for Co, Zn, Pb and Fe at ambient temperature and pH12. For the crystallized slags, leaching of base metals increased with the increase of temperature from ambient temperature to 60°C and decreased at the higher temperature of 80°C due to the evaporation of the ammonia solution used for basic leaching, the total amounts of base metals that were leached in slow cooled slags were very low compared to the quenched slag samples.

Heavy Metals Transport in the Soil Profiles under the Application of Sludge and Wastewater

Heavy metal transfer in soil profiles is a major environmental concern because even slow transport through the soil may eventually lead to deterioration of groundwater quality. The use of sewage sludge and effluents from wastewater treatment plants for irrigation of agricultural lands is on the rise particularly in peri-urban area of developing countries. In this study soil samples under sludge application and wastewater irrigation were studied and soil samples were collected in the soil profiles from the surface to 100 cm in depth. For this purpose, three plots were made in a treatment plant in south of Tehran-Iran. First plot was irrigated just with effluent from wastewater treatment plant, second plot with simulated heavy metals concentration equal 50 years irrigation and in third plot sewage sludge and effluent was used. Trace metals concentration (Cd, Cu) were determined for soil samples. The results indicate movement of metals was observed, but the most concentration of metals was found in topsoil samples. The most of Cadmium concentration was measured in the topsoil of plot 3, 4.5mg/kg and Maximum cadmium movement was observed in 0-20 cm. The most concentration of copper was 27.76mg/kg, and maximum percolation in 0-20 cm. Metals (Cd, Cu) were measured in leached water. Preferential flow and metal complexation with soluble organic apparently allow leaching of heavy metals.

Microscopic Analysis of Welded Dental Alloys

Microplasma welding is a less expensive alternative to laser welding in dental technology. The aim of the study was to highlight discontinuities present in the microplasma welded joints of dental base metal alloys by visual analysis. Five base metal alloys designated for fixed prostheses manufacture were selected for the experiments. Using these plates, preliminary tests were conducted by microplasma welding in butt joint configuration, without filler material, bilaterally and with filler material, proper for each base metal. Macroscopic visual inspection was performed to assess carefully the irregularities in the welds. Electron microscopy allowed detection of discontinuities that are not visible to the eye and revealing details regarding location, trajectory, morphology and size of discontinuities. Supplementing visual control with microscopic analysis allows to detect small discontinuities, which escapes the macroscopic control and to make a detailed study of the weld.