Abstract: The excessive use of agricultural pesticides and the
resulting contamination of food and beds of rivers have been a
recurring problem nowadays. Some of these substances can cause
changes in endocrine balance and impair reproductive function of
human and animal population. In the present study, we evaluated the
possible effects of the fungicide cuprous copper oxide Sandoz® on
pregnant Wistar rats. They received a daily oral administration of 103
or 3.103 mg/kg of the fungicide from the 6th to the 15th day of
gestation. On day 21 of gestation, the maternal and fetal toxicity
parameters and indices were determined. The administration of
cuprous oxide (Copper Sandoz) in Wistar rats, the period of
organogenesis, revealed no evidence of maternal toxicity or embryo
at the studied doses.