Abstract: Tire noise has a significant impact on ride quality
and vehicle interior comfort, even at low frequency. Reduction of
tire noise is especially important due to strict state and federal
environmental regulations. The primary sources of tire noise are the
low frequency structure-borne noise and the noise that originates from
the release of trapped air between the tire tread and road surface
during each revolution of the tire. The frequency response of the tire
changes at low and high frequency. At low frequency, the tension
and bending moment become dominant, while the internal structure
and local deformation become dominant at higher frequencies. Here,
we analyze tire response in terms of deformation and rolling velocity
at low revolution frequency. An Abaqus FEA finite element model
is used to calculate the static and dynamic response of a rolling tire
under different rolling conditions. The natural frequencies and mode
shapes of a deformed tire are calculated with the FEA package where
the subspace-based steady state dynamic analysis calculates dynamic
response of tire subjected to harmonic excitation. The analysis was
conducted on the dynamic response at the road (contact point of tire
and road surface) and side nodes of a static and rolling tire when
the tire was excited with 200 N vertical load for a frequency ranging
from 20 to 200 Hz. The results show that frequency has little effect on
tire deformation up to 80 Hz. But between 80 and 200 Hz, the radial
and lateral components of displacement of the road and side nodes
exhibited significant oscillation. For the static analysis, the fluctuation
was sharp and frequent and decreased with frequency. In contrast, the
fluctuation was periodic in nature for the dynamic response of the
rolling tire. In addition to the dynamic analysis, a steady state rolling
analysis was also performed on the tire traveling at ground velocity
with a constant angular motion. The purpose of the computation
was to demonstrate the effect of rotating motion on deformation and
rolling velocity with respect to a fixed Newtonian reference point.
The analysis showed a significant variation in deformation and rolling
velocity due to centrifugal and Coriolis acceleration with respect to
a fixed Newtonian point on ground.
Abstract: Jesus and Socrates shared a remarkable gift; a channel of inner spiritual communication, to afford them truthful guidance in their respective religious discourse. Jesus is part of the Trinity; he is the Son, the Son of God. In mortal life he is the son of a carpenter. He called on all peoples to repent of their sins but fell foul of the authorities and was crucified. Socrates was an ancient Greek philosopher and the son of an artisan. His mission is to drive the Athenians to investigate truth, but he too incurs the displeasure of fellow citizens, to the extent of execution. The accusations made against them centre around, in Jesus’ case, proclaiming himself the Son of God, with the means to pardon, and in Socrates’, that a daimonion, an inner voice, speaks to him in his heart. Jesus talks with God directly through prayer, as the pneuma of God, i.e. to pneuma to hagion, or Holy Spirit, is with him. Socrates seems to enter what we would now think of as a trance-like condition, wherein he communicates with his inner daimonion, who directs him to take courage on the righteous path.
Abstract: Bullet penetration in steel plate is investigated with
the help of three-dimensional, non-linear, transient, dynamic, finite
elements analysis using explicit time integration code LSDYNA. The
effect of large strain, strain-rate and temperature at very high velocity
regime was studied from number of simulations of semi-spherical
nose shape bullet penetration through single layered circular plate
with 2 mm thickness at impact velocities of 500, 1000, and 1500 m/s
with the help of Johnson Cook material model. Mie-Gruneisen
equation of state is used in conjunction with Johnson Cook material
model to determine pressure-volume relationship at various points of
interests. Two material models viz. Plastic-Kinematic and Johnson-
Cook resulted in different deformation patterns in steel plate. It is
observed from the simulation results that the velocity drop and loss of
kinetic energy occurred very quickly up to perforation of plate, after
that the change in velocity and changes in kinetic energy are
negligibly small. The physics behind this kind of behaviour is
presented in the paper.
Abstract: Deteriorating quality of the pedestrian environment
and the increasing risk of pedestrian crashes are major concerns for
most of the cities in India. The recent shift in the priority to
motorized transport and the abating condition of existing pedestrian
facilities can be considered as prime reasons for the increasing
pedestrian related crashes in India. Bengaluru City – the IT capital
hub of the nation is not much different from this. The increase in
number of pedestrian crashes in Bengaluru reflects the same. To
resolve this issue and to ensure safe, sustainable and pedestrian
friendly sidewalks, Govt. of Karnataka, India has implemented
newfangled pedestrian sidewalks popularized programme named
Tender S.U.R.E. (Specifications for Urban Road Execution) projects.
Tender SURE adopts unique urban street design guidelines where the
pedestrians are given prime preference. The present study presents an
assessment of the quality and performance of the pedestrian side walk
and the walkability index of the newly built pedestrian friendly
sidewalks. Various physical and environmental factors affecting
pedestrian safety are identified and studied in detail. The pedestrian
mobility is quantified through Pedestrian Level of Service (PLoS)
and the pedestrian walking comfort is measured by calculating the
Walkability Index (WI). It is observed that the new initiatives taken
in reference to improving pedestrian safety have succeeded in
Bengaluru by attaining a level of Service of ‘A’ and with a good WI
score.
Abstract: Background: Islands in the Mediterranean region offer
opportunities for various industries to take advantage of the
facilitation and use of versatile floating structures in coastal areas. In
the context of dense land use, marine structures can contribute to
ensure both terrestrial and marine resource sustainability. Objective:
The aim of this paper is to present and critically discuss an array of
issues that characterize the design process of a floating structure for
coastal areas and to present the challenges and opportunities of
providing such multifunctional and versatile structures around the
Maltese coastline. Research Design: A three-tier research design
commenced with a systematic literature review. Semi-structured
interviews with stakeholders including a naval architect, a marine
engineer and civil designers were conducted. A second stage
preceded a focus group with stakeholders in design and construction
of marine lightweight structures. The three tier research design
ensured triangulation of issues. All phases of the study were
governed by research ethics. Findings: Findings were grouped into
three main themes: excellence, impact and implementation. These
included design considerations, applications and potential impacts on
local industry. Literature for the design and construction of marine
structures in the Maltese Islands presented multiple gaps in the
application of marine structures for local industries. Weather
conditions, depth of sea bed and wave actions presented limitations
on the design capabilities of the structure. Conclusion: Water
structures offer great potential and conclusions demonstrate the
applicability of such designs for Maltese waters. There is still no such
provision within Maltese coastal areas for multi-purpose use. The
introduction of such facilities presents a range of benefits for visiting
tourists and locals thereby offering wide range of services to tourism
and marine industry. Costs for construction and adverse weather
conditions were amongst the main limitations that shaped design
capacities of the water structures.
Abstract: In terms of ITS, information on link characteristic is an essential factor for plan or operation. But in practical cases, not every link has installed sensors on it. The link that does not have data on it is called “Missing Link”. The purpose of this study is to impute data of these missing links. To get these data, this study applies the machine learning method. With the machine learning process, especially for the deep learning process, missing link data can be estimated from present link data. For deep learning process, this study uses “Recurrent Neural Network” to take time-series data of road. As input data, Dedicated Short-range Communications (DSRC) data of Dalgubul-daero of Daegu Metropolitan Area had been fed into the learning process. Neural Network structure has 17 links with present data as input, 2 hidden layers, for 1 missing link data. As a result, forecasted data of target link show about 94% of accuracy compared with actual data.
Abstract: The Extended Enterprise Resource Planning (ERPII)
system usually requires massive amounts of storage space, powerful
servers, and large upfront and ongoing investments to purchase and
manage the software and the related hardware which are not
affordable for organizations. In recent decades, organizations prefer
to adapt their business structures with new technologies for
remaining competitive in the world economy. Therefore, cloud
computing (which is one of the tools of information technology (IT))
is a modern system that reveals the next-generation application
architecture. Also, cloud computing has had some advantages that
reduce costs in many ways such as: lower upfront costs for all
computing infrastructure and lower cost of maintaining and
supporting. On the other hand, traditional ERPII is not responding for
huge amounts of data and relations between the organizations. In this
study, based on a literature study, ERPII is investigated in the context
of cloud computing where the organizations operate more efficiently.
Also, ERPII conditions have a response to needs of organizations in
large amounts of data and relations between the organizations.
Abstract: The IEEE 802.15.4 standard is designed for low-rate wireless personal area networks (LR-WPAN) with focus on enabling wireless sensor networks. It aims to give a low data rate, low power consumption, and low cost wireless networking on the device-level communication. The objective of this study is to investigate the performance of IEEE 802.15.4 based networks using simulation tool. In this project the network simulator 2 NS2 was used to several performance measures of wireless sensor networks. Three scenarios were considered, multi hop network with a single coordinator, star topology, and an ad hoc on demand distance vector AODV. Results such as packet delivery ratio, hop delay, and number of collisions are obtained from these scenarios.
Abstract: Minimizing the weight in flexible structures means
reducing material and costs as well. However, these structures could
become prone to vibrations. Attenuating these vibrations has become
a pivotal engineering problem that shifted the focus of many research
endeavors. One technique to do that is to design and implement
an active control system. This system is mainly composed of a
vibrating structure, a sensor to perceive the vibrations, an actuator
to counteract the influence of disturbances, and finally a controller to
generate the appropriate control signals. In this work, two different
techniques are explored to create two different mathematical models
of an active control system. The first model is a finite element model
with a reduced number of nodes and it is called a super-element.
The second model is in the form of state-space representation, i.e.
a set of partial differential equations. The damping coefficients are
calculated and incorporated into both models. The effectiveness of
these models is demonstrated when the system is excited by its first
natural frequency and an active control strategy is developed and
implemented to attenuate the resulting vibrations. Results from both
modeling techniques are presented and compared.
Abstract: An increasing degree of automation in air traffic will also change the role of the air traffic controller (ATCO). ATCOs will fulfill significantly more monitoring tasks compared to today. However, this rather passive role may lead to Out-Of-The-Loop (OOTL) effects comprising vigilance decrement and less situation awareness. The project MINIMA (Mitigating Negative Impacts of Monitoring high levels of Automation) has conceived a system to control and mitigate such OOTL phenomena. In order to demonstrate the MINIMA concept, an experimental simulation set-up has been designed. This set-up consists of two parts: 1) a Task Environment (TE) comprising a Terminal Maneuvering Area (TMA) simulator as well as 2) a Vigilance and Attention Controller (VAC) based on neurophysiological data recording such as electroencephalography (EEG) and eye-tracking devices. The current vigilance level and the attention focus of the controller are measured during the ATCO’s active work in front of the human machine interface (HMI). The derived vigilance level and attention trigger adaptive automation functionalities in the TE to avoid OOTL effects. This paper describes the full-scale experimental set-up and the component development work towards it. Hence, it encompasses a pre-test whose results influenced the development of the VAC as well as the functionalities of the final TE and the two VAC’s sub-components.
Abstract: A crucial component to the success of any financial advising relationship is for the financial professional to understand the perceptions, preferences and thought-processes carried by the financial clients they serve. Armed with this information, financial professionals are more quickly able to understand how they can tailor their approach to best match the individual preferences and needs of each personal investor. Our research explores the use of a quantitative assessment tool in the financial services industry to assist in the identification of the personal investor’s consumer behaviors, especially in terms of financial risk tolerance, as it relates to their financial decision making. Through this process, the Unitifi Consumer Insight Tool (UCIT) was created and refined to capture and categorize personal investor financial behavioral categories and the financial personality tendencies of individuals prior to the initiation of a financial advisement relationship. This paper discusses the use of this tool to place individuals in one of four behavior-based financial risk tolerance categories. Our discoveries and research were aided through administration of a web-based survey to a group of over 1,000 individuals. Our findings indicate that it is possible to use a quantitative assessment tool to assist in predicting the behavioral tendencies of personal consumers when faced with consumer financial risk and decisions.
Abstract: With recent trends in Big Data and advancements
in Information and Communication Technologies, the healthcare
industry is at the stage of its transition from clinician oriented to
technology oriented. Many people around the world die of cancer
because the diagnosis of disease was not done at an early stage.
Nowadays, the computational methods in the form of Machine
Learning (ML) are used to develop automated decision support
systems that can diagnose cancer with high confidence in a timely
manner. This paper aims to carry out the comparative evaluation
of a selected set of ML classifiers on two existing datasets: breast
cancer and cervical cancer. The ML classifiers compared in this study
are Decision Tree (DT), Support Vector Machine (SVM), k-Nearest
Neighbor (k-NN), Logistic Regression, Ensemble (Bagged Tree) and
Artificial Neural Networks (ANN). The evaluation is carried out based
on standard evaluation metrics Precision (P), Recall (R), F1-score and
Accuracy. The experimental results based on the evaluation metrics
show that ANN showed the highest-level accuracy (99.4%) when
tested with breast cancer dataset. On the other hand, when these
ML classifiers are tested with the cervical cancer dataset, Ensemble
(Bagged Tree) technique gave better accuracy (93.1%) in comparison
to other classifiers.
Abstract: The rapid progress of technology in today's competitive conditions has also accelerated companies' technology development activities. As a result, companies are paying more attention to R&D studies and are beginning to allocate a larger share to R&D projects. A more systematic, comprehensive, target-oriented implementation of R&D studies is crucial for the company to achieve successful results. As a consequence, Technology Roadmap (TRM) is gaining importance as a management tool. It has critical prospects for achieving medium and long term success as it contains decisions about past business, future plans, technological infrastructure. When studies on TRM are examined, projects to be placed on the roadmap are selected by many different methods. Generally preferred methods are based on multi-criteria decision making methods. Management of selected projects becomes an important point after the selection phase of the projects. At this stage, TRM are used. TRM can be created in many different ways so that each institution can prepare its own Technology Roadmap according to their strategic plan. Depending on the intended use, there can be TRM with different layers at different sizes. In the evaluation phase of the R&D projects and in the creation of the TRM, HAVELSAN, Turkey's largest defense company in the software field, carries out this process with great care and diligence. At the beginning, suggested R&D projects are evaluated by the Technology Management Board (TMB) of HAVELSAN in accordance with the company's resources, objectives, and targets. These projects are presented to the TMB periodically for evaluation within the framework of certain criteria by board members. After the necessary steps have been passed, the approved projects are added to the time-based TRM, which is composed of four layers as market, product, project and technology. The use of a four-layered roadmap provides a clearer understanding and visualization of company strategy and objectives. This study demonstrates the benefits of using TRM, four-layered Technology Roadmapping and the possibilities for the institutions in the defense industry.
Abstract: The current paper presents a structural assessment and proposals for retrofit of the National Youth Foundation Building, an existing reinforced concrete (RC) building in the city of Igoumenitsa, Greece. The building is scheduled to be renovated in order to create a Municipal Cultural Center. The bearing capacity and structural integrity have been investigated in relation to the provisions and requirements of the Greek Retrofitting Code (KAN.EPE.) and European Standards (Eurocodes). The capacity of the existing concrete structure that makes up the two central buildings in the complex (buildings II and IV) has been evaluated both in its present form and after including several proposed architectural interventions. The structural system consists of spatial frames of columns and beams that have been simulated using beam elements. Some RC elements of the buildings have been strengthened in the past by means of concrete jacketing and have had cracks sealed with epoxy injections. Static-nonlinear analysis (Pushover) has been used to assess the seismic performance of the two structures with regard to performance level B1 from KAN.EPE. Retrofitting scenarios are proposed for the two buildings, including type Λ steel bracings and placement of concrete shear walls in the transverse direction in order to achieve the design-specification deformation in each applicable situation, improve the seismic performance, and reduce the number of interventions required.
Abstract: 5-FU is a chemotherapeutic agent that has been used in colorectal cancer (CRC) treatment. However, it is usually associated with the acquired resistance, which decreases the therapeutic effects of 5-FU. miR-200c is involved in chemotherapeutic drug resistance, but its mechanism is not fully understood. In this study, the effect of inhibition of miR-200c in sensitivity of HCT-116 CRC cells to 5-FU was evaluated. HCT-116 cells were transfected with LNA-anti- miR-200c for 48 h. mRNA expression of miR-200c was evaluated using quantitative real- time PCR. The protein expression of phosphatase and tensin homolog (PTEN) and E-cadherin were analyzed by western blotting. Annexin V and propidium iodide staining assay were applied for apoptosis detection. The caspase-3 activation was evaluated by an enzymatic assay. The results showed LNA-anti-miR-200c inhibited the expression of PTEN and E-cadherin protein, apoptosis and activation of caspase 3 compared with control cells. In conclusion, these results suggest that miR-200c as a prognostic marker can overcome to 5-FU chemoresistance in CRC.
Abstract: Traffic congestion is a worldwide issue, especially in developing countries. This is also the case of Afghanistan, especially in Kabul-the capital city, whose rapid population growth makes it the fifth fastest growing city in the world. Traffic congestion affects not only the mobility of people and goods but also the air quality that leads to numerous deaths (3000 people) every year. There are many factors that contribute to traffic congestion. The insufficiency and inefficiency of public transportation system along with the increase of private vehicles can be considered among the most important contributing factors. This paper addresses the traffic congestion and attempts to suggest possible solutions that can help improve the current public transportation system in Kabul. To this end, the methodology used in this paper includes field work conducted in Kabul city and literature review. The outcome suggests that improving the public transportation system is likely to contribute to the reduction of traffic congestion and the improvement of air quality, thereby reducing the number of death related to air quality.
Abstract: This paper studies a case where the targeted surface roughness of fused deposition modeling (FDM) additive manufacturing process is improved. The process is designing to reduce or eliminate the defects and improve the process capability index Cp and Cpk for an FDM additive manufacturing process. The baseline Cp is 0.274 and Cpk is 0.654. This research utilizes the Taguchi methodology, to eliminate defects and improve the process. The Taguchi method is used to optimize the additive manufacturing process and printing parameters that affect the targeted surface roughness of FDM additive manufacturing. The Taguchi L9 orthogonal array is used to organize the parameters' (four controllable parameters and one non-controllable parameter) effectiveness on the FDM additive manufacturing process. The four controllable parameters are nozzle temperature [°C], layer thickness [mm], nozzle speed [mm/s], and extruder speed [%]. The non-controllable parameter is the environmental temperature [°C]. After the optimization of the parameters, a confirmation print was printed to prove that the results can reduce the amount of defects and improve the process capability index Cp from 0.274 to 1.605 and the Cpk from 0.654 to 1.233 for the FDM additive manufacturing process. The final results confirmed that the Taguchi methodology is sufficient to improve the surface roughness of FDM additive manufacturing process.
Abstract: The objective of this research is to optimize the process of cutting cylindrical workpieces utilizing live tooling on a HAAS ST-20 lathe. Surface roughness (Ra) has been investigated as the indicator of quality characteristics for machining process. Aluminum alloy was used to conduct experiments due to its wide range usages in engineering structures and components where light weight or corrosion resistance is required. In this study, Taguchi methodology is utilized to determine the effects that each of the parameters has on surface roughness (Ra). A total of 18 experiments of each process were designed according to Taguchi’s L9 orthogonal array (OA) with four control factors at three levels of each and signal-to-noise ratios (S/N) were computed with Smaller the better equation for minimizing the system. The optimal parameters identified for the surface roughness of the turning operation utilizing live tooling were a feed rate of 3 inches/min(A3); a spindle speed of 1300 rpm(B3); a 2-flute titanium nitrite coated 3/8” endmill (C1); and a depth of cut of 0.025 inches (D2). The mean surface roughness of the confirmation runs in turning operation was 8.22 micro inches. The final results demonstrate that Taguchi methodology is a sufficient way of process improvement in turning process on surface roughness.
Abstract: Low-temperature waste heat is abundant in the process industries, and large amounts of Liquefied Natural Gas (LNG) cold energy are discarded without being recovered properly in LNG terminals. Power generation is an effective way to utilize low-temperature waste heat and LNG cold energy simultaneously. Organic Rankine Cycles (ORCs) and CO2 power cycles are promising technologies to convert low-temperature waste heat and LNG cold energy into electricity. If waste heat and LNG cold energy are utilized simultaneously in one system, the performance may outperform separate systems utilizing low-temperature waste heat and LNG cold energy, respectively. Low-temperature waste heat acts as the heat source and LNG regasification acts as the heat sink in the combined system. Due to the large temperature difference between the heat source and the heat sink, cascaded power cycle configurations are proposed in this paper. Cascaded power cycles can improve the energy efficiency of the system considerably. The cycle operating at a higher temperature to recover waste heat is called top cycle and the cycle operating at a lower temperature to utilize LNG cold energy is called bottom cycle in this study. The top cycle condensation heat is used as the heat source in the bottom cycle. The top cycle can be an ORC, transcritical CO2 (tCO2) cycle or supercritical CO2 (sCO2) cycle, while the bottom cycle only can be an ORC due to the low-temperature range of the bottom cycle. However, the thermodynamic path of the tCO2 cycle and sCO2 cycle are different from that of an ORC. The tCO2 cycle and the sCO2 cycle perform better than an ORC for sensible waste heat recovery due to a better temperature match with the waste heat source. Different combinations of the tCO2 cycle, sCO2 cycle and ORC are compared to screen the best configurations of the cascaded power cycles. The influence of the working fluid and the operating conditions are also investigated in this study. Each configuration is modeled and optimized in Aspen HYSYS. The results show that cascaded tCO2/ORC performs better compared with cascaded ORC/ORC and cascaded sCO2/ORC for the case study.
Abstract: The comparisons of mycobacterial genomes have identified several Mycobacterium tuberculosis-specific genomic regions that are absent in other mycobacteria and are known as regions of differences. Due to M. tuberculosis-specificity, the peptides encoded by these regions could be useful in the specific diagnosis of tuberculosis. To explore this possibility, overlapping synthetic peptides corresponding to 39 proteins predicted to be encoded by genes present in regions of differences were tested for antibody-reactivity with sera from tuberculosis patients and healthy subjects. The results identified four immunodominant peptides corresponding to four different proteins, with three of the peptides showing significantly stronger antibody reactivity and rate of positivity with sera from tuberculosis patients than healthy subjects. The fourth peptide was recognized equally well by the sera of tuberculosis patients as well as healthy subjects. Predication of antibody epitopes by bioinformatics analyses using ABCpred server predicted multiple linear epitopes in each peptide. Furthermore, peptide sequence analysis for sequence identity using BLAST suggested M. tuberculosis-specificity for the three peptides that had preferential reactivity with sera from tuberculosis patients, but the peptide with equal reactivity with sera of TB patients and healthy subjects showed significant identity with sequences present in nob-tuberculous mycobacteria. The three identified M. tuberculosis-specific immunodominant peptides may be useful in the serological diagnosis of tuberculosis.