Development of an Immunoassay Platform for Diagnosis of Acute Kidney Injury

Acute kidney injury (AKI) is a new worldwide public health problem. A diagnosis of this disease using creatinine is still a problem in clinical practice. Therefore, a measurement of biomarkers responsible for AKI has received much attention in the past couple years. Cytokine interleukin-18 (IL-18) was reported as one of the early biomarkers for AKI. The most commonly used method to detect this biomarker is an immunoassay. This study used a planar platform to perform an immunoassay using fluorescence for detection. In this study, anti-IL-18 antibody was immobilized onto a microscope slide using a covalent binding method. Make-up samples were diluted at the concentration between 10 to 1000 pg/ml to create a calibration curve. The precision of the system was determined using a coefficient of variability (CV), which was found to be less than 10%. The performance of this immunoassay system was compared with the measurement from ELISA.

A Modular On-line Profit Sharing Approach in Multiagent Domains

How to coordinate the behaviors of the agents through learning is a challenging problem within multi-agent domains. Because of its complexity, recent work has focused on how coordinated strategies can be learned. Here we are interested in using reinforcement learning techniques to learn the coordinated actions of a group of agents, without requiring explicit communication among them. However, traditional reinforcement learning methods are based on the assumption that the environment can be modeled as Markov Decision Process, which usually cannot be satisfied when multiple agents coexist in the same environment. Moreover, to effectively coordinate each agent-s behavior so as to achieve the goal, it-s necessary to augment the state of each agent with the information about other existing agents. Whereas, as the number of agents in a multiagent environment increases, the state space of each agent grows exponentially, which will cause the combinational explosion problem. Profit sharing is one of the reinforcement learning methods that allow agents to learn effective behaviors from their experiences even within non-Markovian environments. In this paper, to remedy the drawback of the original profit sharing approach that needs much memory to store each state-action pair during the learning process, we firstly address a kind of on-line rational profit sharing algorithm. Then, we integrate the advantages of modular learning architecture with on-line rational profit sharing algorithm, and propose a new modular reinforcement learning model. The effectiveness of the technique is demonstrated using the pursuit problem.

Modeling and Performance Evaluation of LTE Networks with Different TCP Variants

Long Term Evolution (LTE) is a 4G wireless broadband technology developed by the Third Generation Partnership Project (3GPP) release 8, and it's represent the competitiveness of Universal Mobile Telecommunications System (UMTS) for the next 10 years and beyond. The concepts for LTE systems have been introduced in 3GPP release 8, with objective of high-data-rate, low-latency and packet-optimized radio access technology. In this paper, performance of different TCP variants during LTE network investigated. The performance of TCP over LTE is affected mostly by the links of the wired network and total bandwidth available at the serving base station. This paper describes an NS-2 based simulation analysis of TCP-Vegas, TCP-Tahoe, TCPReno, TCP-Newreno, TCP-SACK, and TCP-FACK, with full modeling of all traffics of LTE system. The Evaluation of the network performance with all TCP variants is mainly based on throughput, average delay and lost packet. The analysis of TCP performance over LTE ensures that all TCP's have a similar throughput and the best performance return to TCP-Vegas than other variants.

Knowledge Relationship Model among User in Virtual Community

With the development of virtual communities, there is an increase in the number of members in Virtual Communities (VCs). Many join VCs with the objective of sharing their knowledge and seeking knowledge from others. Despite the eagerness of sharing knowledge and receiving knowledge through VCs, there is no standard of assessing ones knowledge sharing capabilities and prospects of knowledge sharing. This paper developed a vector space model to assess the knowledge sharing prospect of VC users.

Demand and Supply Chain Simulation in Telecommunication Industry by Multi-Rate Expert Systems

In modern telecommunications industry, demand & supply chain management (DSCM) needs reliable design and versatile tools to control the material flow. The objective for efficient DSCM is reducing inventory, lead times and related costs in order to assure reliable and on-time deliveries from manufacturing units towards customers. In this paper the multi-rate expert system based methodology for developing simulation tools that would enable optimal DSCM for multi region, high volume and high complexity manufacturing environment was proposed.

Phase Noise Impact on BER in Space Communication

This paper deals with the modeling and the evaluation of a multiplicative phase noise influence on the bit error ratio in a general space communication system. Our research is focused on systems with multi-state phase shift keying modulation techniques and it turns out, that the phase noise significantly affects the bit error rate, especially for higher signal to noise ratios. These results come from a system model created in Matlab environment and are shown in a form of constellation diagrams and bit error rate dependencies. The change of a user data bit rate is also considered and included into simulation results. Obtained outcomes confirm theoretical presumptions.

Remarks Regarding Queuing Model and Packet Loss Probability for the Traffic with Self-Similar Characteristics

Network management techniques have long been of interest to the networking research community. The queue size plays a critical role for the network performance. The adequate size of the queue maintains Quality of Service (QoS) requirements within limited network capacity for as many users as possible. The appropriate estimation of the queuing model parameters is crucial for both initial size estimation and during the process of resource allocation. The accurate resource allocation model for the management system increases the network utilization. The present paper demonstrates the results of empirical observation of memory allocation for packet-based services.

Web Based Real Time Laboratory Applications of Analog and Digital Communication Courses with Lab VIEW Access

Developments in scientific and technical area cause to use new methods and techniques in education, as is the case in all fields. Especially, the internet contributes a variety of new methods to design virtual and real time laboratory applications in education. In this study, a real time virtual laboratory is designed and implemented for analog and digital communications laboratory experiments by using Lab VIEW program for Marmara University Electronics-Communication Department. In this application, students can access the virtual laboratory web site and perform their experiments without any limitation of time and location so as the students can observe the signals by changing the parameters of the experiment and evaluate the results.

Social Relation between the Malays and Chinese Communities from a Civilizational Perspectives

Towards the end of 19th century, the discovery of tin and the growing importance of rubber, had led Malaya to once again become the centre of attraction to western colonization, which later on caused the region to be influxed by cheap labour from China and India. One of the factors which attracted the alien communities was the characteristics of social relation offered by the Malays. If one analyzes the history of social relation of the Malays either among themselves or their relation with alien communities, it is apparent that the community places high regards to values such as tolerant, cooperative, respectful and helpful with each other. In fact, all these values are deeply rooted in the value of 'budi'. With the arrival of Islam, the value of 'budi' had been well assimilated with Islamic values thus giving birth to the value of 'budi-Islam'. Through 'budi- Islam', the Malay conducted their dealings with British as well the other communities during the time of peace or conflict. This value is well nurtured due to the geographical circumstances like the fertile, naturally rich land and bountiful marine life. Besides, a set of Malay customs known as 'adat' custom contributed in enhancing the values of budi.

Prioritizing Influential Factors on the Promotion of Virtual Training System

In today's world where everything is rapidly changing and information technology is high in development, many features of culture, society, politic and economy has changed. The advent of information technology and electronic data transmission lead to easy communication and fields like e-learning and e-commerce, are accessible for everyone easily. One of these technologies is virtual training. The "quality" of such kind of education systems is critical. 131 questionnaires were prepared and distributed among university student in Toba University. So the research has followed factors that affect the quality of learning from the perspective of staff, students, professors and this type of university. It is concluded that the important factors in virtual training are the quality of professors, the quality of staff, and the quality of the university. These mentioned factors were the most prior factors in this education system and necessary for improving virtual training.

Roundabout Optimal Entry and Circulating Flow Induced by Road Hump

Roundabout work on the principle of circulation and entry flows, where the maximum entry flow rates depend largely on circulating flow bearing in mind that entry flows must give away to circulating flows. Where an existing roundabout has a road hump installed at the entry arm, it can be hypothesized that the kinematics of vehicles may prevent the entry arm from achieving optimum performance. Road humps are traffic calming devices placed across road width solely as speed reduction mechanism. They are the preferred traffic calming option in Malaysia and often used on single and dual carriageway local routes. The speed limit on local routes is 30mph (50 km/hr). Road humps in their various forms achieved the biggest mean speed reduction (based on a mean speed before traffic calming of 30mph) of up to 10mph or 16 km/hr according to the UK Department of Transport. The underlying aim of reduced speed should be to achieve a 'safe' distribution of speeds which reflects the function of the road and the impacts on the local community. Constraining safe distribution of speeds may lead to poor drivers timing and delayed reflex reaction that can probably cause accident. Previous studies on road hump impact have focused mainly on speed reduction, traffic volume, noise and vibrations, discomfort and delay from the use of road humps. The paper is aimed at optimal entry and circulating flow induced by road humps. Results show that roundabout entry and circulating flow perform better in circumstances where there is no road hump at entrance.

Real-Time Hand Tracking and Gesture Recognition System Using Neural Networks

This paper introduces a hand gesture recognition system to recognize real time gesture in unstrained environments. Efforts should be made to adapt computers to our natural means of communication: Speech and body language. A simple and fast algorithm using orientation histograms will be developed. It will recognize a subset of MAL static hand gestures. A pattern recognition system will be using a transforrn that converts an image into a feature vector, which will be compared with the feature vectors of a training set of gestures. The final system will be Perceptron implementation in MATLAB. This paper includes experiments of 33 hand postures and discusses the results. Experiments shows that the system can achieve a 90% recognition average rate and is suitable for real time applications.

The PARADIGMA Approach for Cooperative Work in the Medical Domain

PARADIGMA (PARticipative Approach to DIsease Global Management) is a pilot project which aims to develop and demonstrate an Internet based reference framework to share scientific resources and findings in the treatment of major diseases. PARADIGMA defines and disseminates a common methodology and optimised protocols (Clinical Pathways) to support service functions directed to patients and individuals on matters like prevention, posthospitalisation support and awareness. PARADIGMA will provide a platform of information services - user oriented and optimised against social, cultural and technological constraints - supporting the Health Care Global System of the Euro-Mediterranean Community in a continuous improvement process.

A Remote Sensing Approach for Vulnerability and Environmental Change in Apodi Valley Region, Northeast Brazil

The objective of this study was to improve our understanding of vulnerability and environmental change; it's causes basically show the intensity, its distribution and human-environment effect on the ecosystem in the Apodi Valley Region, This paper is identify, assess and classify vulnerability and environmental change in the Apodi valley region using a combined approach of landscape pattern and ecosystem sensitivity. Models were developed using the following five thematic layers: Geology, geomorphology, soil, vegetation and land use/cover, by means of a Geographical Information Systems (GIS)-based on hydro-geophysical parameters. In spite of the data problems and shortcomings, using ESRI-s ArcGIS 9.3 program, the vulnerability score, to classify, weight and combine a number of 15 separate land cover classes to create a single indicator provides a reliable measure of differences (6 classes) among regions and communities that are exposed to similar ranges of hazards. Indeed, the ongoing and active development of vulnerability concepts and methods have already produced some tools to help overcome common issues, such as acting in a context of high uncertainties, taking into account the dynamics and spatial scale of asocial-ecological system, or gathering viewpoints from different sciences to combine human and impact-based approaches. Based on this assessment, this paper proposes concrete perspectives and possibilities to benefit from existing commonalities in the construction and application of assessment tools.

Securing Message in Wireless Sensor Network by using New Method of Code Conversions

Recently, wireless sensor networks have been paid more interest, are widely used in a lot of commercial and military applications, and may be deployed in critical scenarios (e.g. when a malfunctioning network results in danger to human life or great financial loss). Such networks must be protected against human intrusion by using the secret keys to encrypt the exchange messages between communicating nodes. Both the symmetric and asymmetric methods have their own drawbacks for use in key management. Thus, we avoid the weakness of these two cryptosystems and make use of their advantages to establish a secure environment by developing the new method for encryption depending on the idea of code conversion. The code conversion-s equations are used as the key for designing the proposed system based on the basics of logic gate-s principals. Using our security architecture, we show how to reduce significant attacks on wireless sensor networks.

Efficient Sensors Selection Algorithm in Cyber Physical System

Cyber physical system (CPS) for target tracking, military surveillance, human health monitoring, and vehicle detection all require maximizing the utility and saving the energy. Sensor selection is one of the most important parts of CPS. Sensor selection problem (SSP) is concentrating to balance the tradeoff between the number of sensors which we used and the utility which we will get. In this paper, we propose a performance constrained slide windows (PCSW) based algorithm for SSP in CPS. we present results of extensive simulations that we have carried out to test and validate the PCSW algorithms when we track a target, Experiment shows that the PCSW based algorithm improved the performance including selecting time and communication times for selecting.

An Efficient Mobile Payment System Based On NFC Technology

The work we have accomplished in implementing a Mobile Payment mechanism that enables customers to pay bills for groceries and other purchased items in a store through the means of a mobile phone, specifically a Smartphone. The mode of transaction, as far as communication between the customer-s handset and the merchant-s POS is concerned, we have decided upon NFC (Near Field Communication). This is due to the fact that for the most part, Pakistani Smartphone users have handsets that have Android mobile OS, which supports the aforementioned platform, IOS, on the other hand does not.

Engagement Strategies for Stakeholder Management in New Technology Development in the Fertilizer Industry – A Conceptual Framework

Communication is becoming a significant tool to engage stakeholders since half of the century ago. In the recent years, there has been rapid growth of new technology developments. In tandem with such developments, there has been growing emphasis in communication strategies and management especially in determining the level of influence and management strategies among the said stakeholders on particular field. This paper presents a research conceptual framework focusing on stakeholder theories, communication and management strategies to be implied on the engagement of stakeholders of new technology developments of fertilizer industry in Malaysia. Framework espoused in this paper will provide insights into the various stakeholder theories and engagement strategies from different principal necessary for a successful introduction of new technology development in the above stated industry. The proposed framework has theoretical significance in filling the gap of the body of knowledge in the implementation of communication strategies in Malaysian fertilizer industry.

Dynamic Capitalization and Visualization Strategy in Collaborative Knowledge Management System for EI Process

Knowledge is attributed to human whose problemsolving behavior is subjective and complex. In today-s knowledge economy, the need to manage knowledge produced by a community of actors cannot be overemphasized. This is due to the fact that actors possess some level of tacit knowledge which is generally difficult to articulate. Problem-solving requires searching and sharing of knowledge among a group of actors in a particular context. Knowledge expressed within the context of a problem resolution must be capitalized for future reuse. In this paper, an approach that permits dynamic capitalization of relevant and reliable actors- knowledge in solving decision problem following Economic Intelligence process is proposed. Knowledge annotation method and temporal attributes are used for handling the complexity in the communication among actors and in contextualizing expressed knowledge. A prototype is built to demonstrate the functionalities of a collaborative Knowledge Management system based on this approach. It is tested with sample cases and the result showed that dynamic capitalization leads to knowledge validation hence increasing reliability of captured knowledge for reuse. The system can be adapted to various domains.

A Study of DSRC Radio Testbed under Heavy Channel Load

Dedicated Short Range Communication (DSRC) is a key enabling technology for the next generation of communication-based safety applications. One of the important problems for DSRC deployment is maintaining high performance under heavy channel load. Many studies focus on congestion control mechanisms for simulating hundreds of physical radios deployed on vehicles. The U.S. department of transportation-s (DOT) Intelligent Transportation Systems (ITS) division has a plan to chosen prototype on-board devices capable of transmitting basic “Here I am" safety messages to other vehicles. The devices will be used in an IntelliDrive safety pilot deployment of up to 3,000 vehicles. It is hard to log the information of 3,000 vehicles. In this paper we present the designs and issues related to the DSRC Radio Testbed under heavy channel load. The details not only include the architecture of DSRC Radio Testbed, but also describe how the Radio Interfere System is used to help for emulating the congestion radio environment.