Abstract: Cardiovascular disease mostly in the form of atherosclerosis is responsible for 30% of all world deaths amounting to 17 million people per year. Atherosclerosis is due to the formation of plaque. The fatty plaque may be at risk of rupture, leading typically to stroke and heart attack. The plaque is usually associated with a high degree of lumen reduction, called a stenosis. The initiation and progression of the disease is strongly linked to the hemodynamic environment near the vessel wall. The aim of this study is to validate the flow of blood mimic through an arterial stenosis model with computational fluid dynamics (CFD) package. In experiment, an axisymmetric model constructed consists of contraction and expansion region that follow a mathematical form of cosine function. A 30% diameter reduction was used in this study. Particle image velocimetry (PIV) was used to characterize the flow. The fluid consists of rigid spherical particles suspended in waterglycerol- NaCl mixture. The particles with 20 μm diameter were selected to follow the flow of fluid. The flow at Re=155, 270 and 390 were investigated. The experimental result is compared with FLUENT simulated flow that account for viscous laminar flow model. The results suggest that laminar flow model was sufficient to predict flow velocity at the inlet but the velocity at stenosis throat at Re =390 was overestimated. Hence, a transition to turbulent regime might have been developed at throat region as the flow rate increases.
Abstract: Many states are now committed to implementing
international human rights standards domestically. In terms of
practical governance, how might effectiveness be measured? A facevalue
answer can be found in domestic laws and institutions relating
to human rights. However, this article provides two further tools to
help states assess their status on the spectrum of robust to fragile
human rights governance. The first recognises that each state has its
own 'human rights history' and the ideal end stage is robust human
rights governance, and the second is developing criteria to assess
robustness. Although a New Zealand case study is used to illustrate
these tools, the widespread adoption of human rights standards by
many states inevitably means that the issues are relevant to other
countries. This is even though there will always be varying degrees of
similarity-difference in constitutional background and developed or
emerging human rights systems.
Abstract: The purpose of this study is two-fold. First, it attempts to explore potential opportunities for utilizing visual interactive simulations along with Business Intelligence (BI) as a decision support tool for strategic decision making. Second, it tries to figure out the essential top-level managerial requirements that would transform strategic decision simulation into an integral component of BI systems. The domain of particular interest was the application of visual interactive simulation capabilities in the field of supply chains. A qualitative exploratory method was applied, through the use of interviews with two leading companies. The collected data was then analysed to demonstrate the difference between the literature perspective and the practical managerial perspective on the issue. The results of the study suggest that although the use of simulation particularly in managing supply chains is very evident in literature, yet, in practice such utilization is still in its infancy, particularly regarding strategic decisions. Based on the insights a prototype of a simulation based BI-solution-extension was developed and evaluated.
Abstract: This paper proposes a new methodology for the
optimal allocation and sizing of Embedded Generation (EG)
employing Real Coded Genetic Algorithm (RCGA) to minimize the
total power losses and to improve voltage profiles in the radial
distribution networks. RCGA is a method that uses continuous
floating numbers as representation which is different from
conventional binary numbers. The RCGA is used as solution tool,
which can determine the optimal location and size of EG in radial
system simultaneously. This method is developed in MATLAB. The
effect of EG units- installation and their sizing to the distribution
networks are demonstrated using 24 bus system.
Abstract: Human activities are increasingly based on the use of remote resources and services, and on the interaction between
remotely located parties that may know little about each other. Mobile agents must be prepared to execute on different hosts with
various environmental security conditions. The aim of this paper is to
propose a trust based mechanism to improve the security of mobile
agents and allow their execution in various environments. Thus, an
adaptive trust mechanism is proposed. It is based on the dynamic interaction between the agent and the environment. Information
collected during the interaction enables generation of an environment
key. This key informs on the host-s trust degree and permits the mobile agent to adapt its execution. Trust estimation is based on
concrete parameters values. Thus, in case of distrust, the source of problem can be located and a mobile agent appropriate behavior can
be selected.
Abstract: Formaldehyde is the illegal chemical substance used
for food preservation in fish and vegetable. It can promote
carcinogenesis. Superoxide dismutases are the important
antioxidative enzymes that catalyze the dismutation of superoxide
anion into oxygen and hydrogen peroxide. The resultant level of
oxidative stress in formaldehyde-treated lymphocytes was
investigated. The formaldehyde concentrations of 0, 20, 40, 60, 80
and 120μmol/L were treated in human lymphocytes for 12 hours.
After 12 treated hours, the superoxide dismutase activity change was
measured in formaldehyde-treated lymphocytes. The results showed
that the formaldehyde concentrations of 60, 80 and 120μmol/L
significantly decreased superoxide dismutase activities in
lymphocytes (P < 0.05). The change of superoxide dismutase
activity in formaldehyde-treated lymphocytes may be the biomarker
for detect cellular injury, such as damage to DNA, due to
formaldehyde exposure.
Abstract: In Public Wireless LANs(PWLANs), user anonymity
is an essential issue. Recently, Juang et al. proposed an anonymous
authentication and key exchange protocol using smart cards in
PWLANs. They claimed that their proposed scheme provided identity
privacy, mutual authentication, and half-forward secrecy. In this paper,
we point out that Juang et al.'s protocol is vulnerable to the
stolen-verifier attack and does not satisfy user anonymity.
Abstract: It has formed an essential issue that Climate Change, composed of highly knowledge complexity, reveals its significant impact on human existence. Therefore, specific national policies, some of which present the educational aspects, have been published for overcoming the imperative problem. Accordingly, the study aims to analyze as well as integrate the relationship between Climate Change and environmental education and apply the perspective of concept map to represent the knowledge contents and structures of Climate Change; by doing so, knowledge contents of Climate Change could be represented in an even more comprehensive way and manipulated as the tool for environmental education. The method adapted for this study is knowledge conversion model compounded of the platform for experts and teachers, who were the participants for this study, to cooperate and combine each participant-s standpoints into a complete knowledge framework that is the foundation for structuring the concept map. The result of this research contains the important concepts, the precise propositions and the entire concept map for representing the robust concepts of Climate Change.
Abstract: This paper presents design trade-off and performance impacts of
the amount of pipeline phase of control path signals in a wormhole-switched
network-on-chip (NoC). The numbers of the pipeline phase of the control
path vary between two- and one-cycle pipeline phase. The control paths
consist of the routing request paths for output selection and the arbitration
paths for input selection. Data communications between on-chip routers are
implemented synchronously and for quality of service, the inter-router data
transports are controlled by using a link-level congestion control to avoid
lose of data because of an overflow. The trade-off between the area (logic
cell area) and the performance (bandwidth gain) of two proposed NoC router
microarchitectures are presented in this paper. The performance evaluation is
made by using a traffic scenario with different number of workloads under
2D mesh NoC topology using a static routing algorithm. By using a 130-nm
CMOS standard-cell technology, our NoC routers can be clocked at 1 GHz,
resulting in a high speed network link and high router bandwidth capacity
of about 320 Gbit/s. Based on our experiments, the amount of control path
pipeline stages gives more significant impact on the NoC performance than
the impact on the logic area of the NoC router.
Abstract: A state of the art Speaker Identification (SI) system
requires a robust feature extraction unit followed by a speaker
modeling scheme for generalized representation of these features.
Over the years, Mel-Frequency Cepstral Coefficients (MFCC)
modeled on the human auditory system has been used as a standard
acoustic feature set for speech related applications. On a recent
contribution by authors, it has been shown that the Inverted Mel-
Frequency Cepstral Coefficients (IMFCC) is useful feature set for
SI, which contains complementary information present in high
frequency region. This paper introduces the Gaussian shaped filter
(GF) while calculating MFCC and IMFCC in place of typical
triangular shaped bins. The objective is to introduce a higher
amount of correlation between subband outputs. The performances
of both MFCC & IMFCC improve with GF over conventional
triangular filter (TF) based implementation, individually as well as
in combination. With GMM as speaker modeling paradigm, the
performances of proposed GF based MFCC and IMFCC in
individual and fused mode have been verified in two standard
databases YOHO, (Microphone Speech) and POLYCOST
(Telephone Speech) each of which has more than 130 speakers.
Abstract: Recent developments in information and
communication technologies (ICT) have created excellent conditions
for profoundly enhancing the traditional learning and teaching
practices. New modes of teaching in higher education subjects can
profoundly enhance ones ability to proactively constructing his or her
personal learning universe. These developments have contributed to
digital learning environments becoming widely available and
accessible. In addition, there is a trend towards enlargement and
specialization in higher education in Europe. With as a result that
existing Master of Science (MSc) programmes are merged or new
programmes have been established that are offered as joint MSc
programmes to students. In these joint MSc programmes, the need for
(common) digital learning environments capable of surmounting the
barriers of time and location has become evident. This paper
discusses the past and ongoing efforts to establish such common
digital learning environments in two joint MSc programmes in
Europe and discusses the way technology-based learning
environments affect the traditional way of learning.
Abstract: This paper focuses on the Mega-Sub Controlled
Structure Systems (MSCSS) performances and characteristics
regarding the new control principle contained in MSCSS subjected to
strong earthquake excitations. The adopted control scheme consists of
modulated sub-structures where the control action is achieved by
viscous dampers and sub-structure own configuration. The
elastic-plastic time history analysis under severe earthquake excitation
is analyzed base on the Finite Element Analysis Method (FEAM), and
some comparison results are also given in this paper. The result shows
that the MSCSS systems can remarkably reduce vibrations effects
more than the mega-sub structure (MSS). The study illustrates that the
improved MSCSS presents good seismic resistance ability even at 1.2g
and can absorb seismic energy in the structure, thus imply that
structural members cross section can be reduce and achieve to good
economic characteristics. Furthermore, the elasto-plastic analysis
demonstrates that the MSCSS is accurate enough regarding
international building evaluation and design codes. This paper also
shows that the elasto-plastic dynamic analysis method is a reasonable
and reliable analysis method for structures subjected to strong
earthquake excitations and that the computed results are more precise.
Abstract: In diversity rich environments, such as in Ultra-
Wideband (UWB) applications, the a priori determination of the
number of strong diversity branches is difficult, because of the considerably large number of diversity paths, which are characterized
by a variety of power delay profiles (PDPs). Several
Rake implementations have been proposed in the past, in order to reduce the number of the estimated and combined paths. To this
aim, we introduce two adaptive Rake receivers, which combine
a subset of the resolvable paths considering simultaneously the
quality of both the total combining output signal-to-noise ratio (SNR) and the individual SNR of each path. These schemes achieve
better adaptation to channel conditions compared to other known receivers, without further increasing the complexity. Their performance
is evaluated in different practical UWB channels, whose models are based on extensive propagation measurements. The
proposed receivers compromise between the power consumption,
complexity and performance gain for the additional paths, resulting in important savings in power and computational resources.
Abstract: Traffic congestion has become a major problem in
many countries. One of the main causes of traffic congestion is due
to road merges. Vehicles tend to move slower when they reach the
merging point. In this paper, an enhanced algorithm for traffic
simulation based on the fluid-dynamic algorithm and kinematic wave
theory is proposed. The enhanced algorithm is used to study traffic
congestion at a road merge. This paper also describes the
development of a dynamic traffic simulation tool which is used as a
scenario planning and to forecast traffic congestion level in a certain
time based on defined parameter values. The tool incorporates the
enhanced algorithm as well as the two original algorithms. Output
from the three above mentioned algorithms are measured in terms of
traffic queue length, travel time and the total number of vehicles
passing through the merging point. This paper also suggests an
efficient way of reducing traffic congestion at a road merge by
analyzing the traffic queue length and travel time.
Abstract: This study presents the improvement of thermal
performance of heat pipe using copper nanofluid with aqueous
solution of n-Butanol. The nanofluids kept in the suspension of
conventional fluids have the potential of superior heat transfer
capability than the conventional fluids due to their improved thermal
conductivity. In this work, the copper nanofluid which has a 40 nm
size with a concentration of 100 mg/lit is kept in the suspension of
the de-ionized (DI) water and an aqueous solution of n-Butanol and
these fluids are used as a working medium in the heat pipe. The study
discusses about the effect of heat pipe inclination, type of working
fluid and heat input on the thermal efficiency and thermal resistance.
The experimental results are evaluated in terms of its performance
metrics and are compared with that of DI water.
Abstract: This study was designed to formulate,
pharmaceutically evaluate a topical skin-care cream (w/o emulsion)
of Aloe Vera versus its vehicle (Base) as control and determine their
effects on Stratum Corneum (SC) water content and Transepidermal
water loss (TEWL). Base containing no extract and a Formulation
containing 3% concentrated extract of Aloe Vera was developed by
entrapping in the inner aqueous phase of w/o emulsion (cream).
Lemon oil was incorporated to improve the odor. Both the Base and
Formulation were stored at 8°C ±0.1°C (in refrigerator), 25°C±0.1°C,
40°C±0.1°C and 40°C± 0.1°C with 75% RH (in incubator) for a
period of 4 weeks to predict their stability. The evaluation parameters
consisted of color, smell, type of emulsion, phase separation,
electrical conductivity, centrifugation, liquefaction and pH. Both the
Base and Formulation were applied to the cheeks of 21 healthy
human volunteers for a period of 8 weeks Stratum corneum (SC)
water content and Transepidermal water loss (TEWL) were
monitored every week to measure any effect produced by these
topical creams. The expected organoleptic stability of creams was
achieved from 4 weeks in-vitro study period. Odor was disappeared
with the passage of time due to volatilization of lemon oil. Both the
Base and Formulation produced significant (p≤0.05) changes in
TEWL with respect to time. SC water content was significantly
(p≤0.05) increased by the Formulation while the Base has
insignificant (p 0.05) effects on SC water content. The newly
formulated cream of Aloe Vera, applied is suitable for improvement
and quantitative monitoring of skin hydration level (SC water
content/ moisturizing effects) and reducing TEWL in people with dry
skin.
Abstract: Six parameters, the effective diffusivity (De),
activation energy of De, pre-exponential factor of De, amount
(ASOW) of self-organized water species, and amplitude (α) of the
forced oscillation of the molecular mobility (1/tC) derived from the
forced cyclic temperature change operation, were characterized by
using six typical foods, squid, sardines, scallops, salmon, beef, and
pork, as a function of the correlation time (tC) of the water molecule-s
proton retained in the foods. Each of the six parameters was clearly
divided into the water species A1 and A2 at a specified value of tC
=10-8s (=CtC), indicating an anomalous change in the physicochemical
nature of the water species at the CtC. The forced oscillation of 1/tC
clearly demonstrated a characteristic mode depending on the food
shown as a three dimensional map associated with 1/tC, the amount of
self-organized water, and tC.
Abstract: Size based filtration is one of the common methods
employed to isolate circulating tumor cells (CTCs) from whole
blood. It is well known that this method suffers from isolation
efficiency to purity tradeoff. However, this tradeoff is poorly
understood. In this paper, we present the design and manufacturing
of a special rectangular slit filter. The filter was designed to retain
maximal amounts of nucleated cells, while minimizing the pressure
on cells, thereby preserving their morphology. The key parameter,
namely, input pressure, was optimized to retain the maximal number
of tumor cells, whilst maximizing the depletion of normal blood cells
(red and white blood cells and platelets). Our results indicate that for
a slit geometry of 5 × 40 μm on a 13 mm circular membrane with a
fill factor of 21%, a pressure of 6.9 mBar yields the optimum for
maximizing isolation of MCF-7 and depletion of normal blood cells.
Abstract: The environment pollution with pesticides and heavy
metals is a recognized problem nowadays, with extension to the
global scale the tendency of amplification. Even with all the progress
in the environmental field, both in the emphasize of the effect of the
pollutants upon health, the linked studies environment-health are
insufficient, not only in Romania but all over the world also. We aim
to describe the particular situation in Romania regarding the
uncontrolled use of pesticides, to identify and evaluate the risk zones
for health and the environment in Romania, with the final goal of
designing adequate programs for reduction and control of the risk
sources. An exploratory study was conducted to determine the
magnitude of the pesticide use problem in a population living in
Saliste, a rural setting in Transylvania, Romania. The significant
stakeholders in Saliste region were interviewed and a sample from
the population living in Saliste area was selected to fill in a designed
questionnaire. All the selected participants declared that they used
pesticides in their activities for more than one purpose. They
declared they annually applied pesticides for a period of time
between 11 and 30 years, from 5 to 9 days per year on average,
mainly on crops situated at some distance from the houses but high
risk behavior was identified as the volunteers declared the use of
pesticides in the backyard gardens, near their homes, where children
were playing. The pesticide applicators did not have the necessary
knowledge about safety and exposure. The health data must be
correlated with exposure biomarkers in attempt to identify the
possible health effects of the pesticides exposure. Future plans
include educational campaigns to raise the awareness of the
population on the danger of uncontrolled use of pesticides.
Abstract: For Romania, the fulfilment of the obligations
undertaken as a member state of the European Union in accordance
with the Treaty of Accession requires the effective implementation of
sustainable development principles and practices, this being the only
reasonable development option, which adequately draws in on the
economic, social and environment resources. Achieving this
objective is based on a profound analysis of the realities in the
Romanian economy, which will reflect the existent situation and the
action directions for the future. The paper presents an analysis of the
Romanian economic performances compared to the EU economy,
based on the sustainable value (SV) model. The analysis highlighted
the considerable gap between Romania and the EU regarding the
sustainable capitalization of resources, the provided information
being useful to justify strategic development decisions at a micro and
macro levels.