Effect of Twelve Weeks Brisk Walking on Blood Pressure, Body Mass Index, and Anthropometric Circumference of Obese Males

Introduction: Obesity is a major health risk issue in the present day of life for one and all globally. Obesity is one of the major concerns for public health according to recent increasing trends in obesity-related diseases such as Type 2 diabetes. ( Kazuya, 1994).and hyperlipidemia, (Sakata,1990) .which are more prevalent in Japanese adults with body mass index (BMI) values Z25 kg/m2.( Japanese Ministry of Health and Welfare,1997). The purpose of the study was to assess the effect of twelve weeks of brisk walking on blood pressure and body mass index, anthropometric measurements of obese males. Method: Thirty obese (BMI= above 30) males, aged 18 to 22 years, were selected from King Fahd University of Petroleum & Minerals, Saudi Arabia. The subject-s height (cm) was measured using a stadiometer and body mass (kg) was measured with a electronic weighing machine. BMI was subsequently calculated (kg/m2). The blood pressure was measured with standardized sphygmomanometer in mm of Hg. All the measurements were taken twice before and twice after the experimental period. The pre and post anthropometric measurements of waist and hip circumference were measured with the steel tape in cm. The subjects underwent walking schedule two times in a week for 12 weeks. The 45 minute sessions of brisk walking were undertaken at an average intensity of 65% to 85% of maximum HR (HRmax; calculated as 220-age). Results & Discussion: Statistical findings revealed significant changes from pre test to post test in case of both systolic blood pressure and diastolic blood pressure in the walking group. Results also showed significant decrease in their body mass index and anthropometric measurements i.e. (waist & hip circumference). Conclusion: It was concluded that twelve weeks brisk walking is beneficial for lowering of blood pressure, body mass index, and anthropometric circumference of obese males.

Obstacles as Switches between Different Cardiac Arrhythmias

Ventricular fibrillation is a very important health problem as is the cause of most of the sudden deaths in the world. Waves of electrical activity are sent by the SA node, propagate through the cardiac tissue and activate the mechanisms of cell contraction, and therefore are responsible to pump blood to the body harmonically. A spiral wave is an abnormal auto sustainable wave that is responsible of certain types of arrhythmias. When these waves break up, give rise to the fibrillation regime, in which there is a complete loss in the coordination of the contraction of the heart muscle. Interaction of spiral waves and obstacles is also of great importance as it is believed that the attachment of a spiral wave to an obstacle can provide with a transition of two different arrhythmias. An obstacle can be partially excitable or non excitable. In this talk, we present a numerical study of the interaction of meandering spiral waves with partially and non excitable obstacles and focus on the problem where the obstacle plays a fundamental role in the switch between different spiral regimes, which represent different arrhythmic regimes. Particularly, we study the phenomenon of destabilization of spiral waves due to the presence of obstacles, a phenomenon not completely understood (This work will appear as a Chapter in a Book named Cardiac Arrhytmias by INTECH under the name "Spiral Waves, Obstacles and Cardiac Arrhythmias", ISBN 979-953-307-050-5.).

A Review of Methods for 2D/3D Registration

2D/3D registration is a special case of medical image registration which is of particular interest to surgeons. Applications of 2D/3D registration are [1] radiotherapy planning and treatment verification, spinal surgery, hip replacement, neurointerventions and aortic stenting. The purpose of this paper is to provide a literature review of the main methods for image registration for the 2D/3D case. At the end of the paper an algorithm is proposed for 2D/3D registration based on the Chebyssev polynomials iteration loop.

A 3D Approach for Extraction of the Coronaryartery and Quantification of the Stenosis

Segmentation and quantification of stenosis is an important task in assessing coronary artery disease. One of the main challenges is measuring the real diameter of curved vessels. Moreover, uncertainty in segmentation of different tissues in the narrow vessel is an important issue that affects accuracy. This paper proposes an algorithm to extract coronary arteries and measure the degree of stenosis. Markovian fuzzy clustering method is applied to model uncertainty arises from partial volume effect problem. The algorithm employs: segmentation, centreline extraction, estimation of orthogonal plane to centreline, measurement of the degree of stenosis. To evaluate the accuracy and reproducibility, the approach has been applied to a vascular phantom and the results are compared with real diameter. The results of 10 patient datasets have been visually judged by a qualified radiologist. The results reveal the superiority of the proposed method compared to the Conventional thresholding Method (CTM) on both datasets.

Real-Time Image Analysis of Capsule Endoscopy for Bleeding Discrimination in Embedded System Platform

Image processing for capsule endoscopy requires large memory and it takes hours for diagnosis since operation time is normally more than 8 hours. A real-time analysis algorithm of capsule images can be clinically very useful. It can differentiate abnormal tissue from health structure and provide with correlation information among the images. Bleeding is our interest in this regard and we propose a method of detecting frames with potential bleeding in real-time. Our detection algorithm is based on statistical analysis and the shapes of bleeding spots. We tested our algorithm with 30 cases of capsule endoscopy in the digestive track. Results were excellent where a sensitivity of 99% and a specificity of 97% were achieved in detecting the image frames with bleeding spots.

On the Verification of Power Nap Associated with Stage 2 Sleep and Its Application

One of the most important causes of accidents is driver fatigue. To reduce the accidental rate, the driver needs a quick nap when feeling sleepy. Hence, searching for the minimum time period of nap is a very challenging problem. The purpose of this paper is twofold, i.e. to investigate the possible fastest time period for nap and its relationship with stage 2 sleep, and to develop an automatic stage 2 sleep detection and alarm device. The experiment for this investigation is designed with 21 subjects. It yields the result that waking up the subjects after getting into stage 2 sleep for 3-5 minutes can efficiently reduce the sleepiness. Furthermore, the automatic stage 2 sleep detection and alarm device yields the real-time detection accuracy of approximately 85% which is comparable with the commercial sleep lab system.

Virtual Environment Design Guidelines for Elderly People in Early Detection of Dementia

Early detection of dementia by testing the spatial memory can be applied using a virtual environment. This paper presents guidelines on how to design a virtual environment specifically for elderly in early detection of dementia. The specific design needs to be considered because the effectiveness of the technology relies on the ability of the end user to use it. The primary goal of these guidelines is to promote accessibility. Based on these guidelines, a virtual simulation was developed and evaluated. The results on usability of acceptance and satisfaction that are tested on young (control group) and elderly participants indicate that these guidelines are reliable and useful for use with elderly people.

An in Silico Approach for Prioritizing Drug Targets in Metabolic Pathway of Mycobacterium Tuberculosis

There is an urgent need to develop novel Mycobacterium tuberculosis (Mtb) drugs that are active against drug resistant bacteria but, more importantly, kill persistent bacteria. Our study structured based on integrated analysis of metabolic pathways, small molecule screening and similarity Search in PubChem Database. Metabolic analysis approaches based on Unified weighted used for potent target selection. Our results suggest that pantothenate synthetase (panC) and and 3-methyl-2-oxobutanoate hydroxymethyl transferase (panB) as a appropriate drug targets. In our study, we used pantothenate synthetase because of existence inhibitors. We have reported the discovery of new antitubercular compounds through ligand based approaches using computational tools.