Abstract: Introduction: Obesity is a major health risk issue in
the present day of life for one and all globally. Obesity is one of the
major concerns for public health according to recent increasing trends
in obesity-related diseases such as Type 2 diabetes. ( Kazuya,
1994).and hyperlipidemia, (Sakata,1990) .which are more prevalent
in Japanese adults with body mass index (BMI) values Z25 kg/m2.(
Japanese Ministry of Health and Welfare,1997). The purpose of the
study was to assess the effect of twelve weeks of brisk walking on
blood pressure and body mass index, anthropometric measurements
of obese males. Method: Thirty obese (BMI= above 30) males, aged
18 to 22 years, were selected from King Fahd University of
Petroleum & Minerals, Saudi Arabia. The subject-s height (cm) was
measured using a stadiometer and body mass (kg) was measured with
a electronic weighing machine. BMI was subsequently calculated
(kg/m2). The blood pressure was measured with standardized
sphygmomanometer in mm of Hg. All the measurements were taken
twice before and twice after the experimental period. The pre and
post anthropometric measurements of waist and hip circumference
were measured with the steel tape in cm. The subjects underwent
walking schedule two times in a week for 12 weeks. The 45 minute
sessions of brisk walking were undertaken at an average intensity of
65% to 85% of maximum HR (HRmax; calculated as 220-age).
Results & Discussion: Statistical findings revealed significant
changes from pre test to post test in case of both systolic blood
pressure and diastolic blood pressure in the walking group. Results
also showed significant decrease in their body mass index and
anthropometric measurements i.e. (waist & hip circumference).
Conclusion: It was concluded that twelve weeks brisk walking is
beneficial for lowering of blood pressure, body mass index, and
anthropometric circumference of obese males.
Abstract: Ventricular fibrillation is a very important health
problem as is the cause of most of the sudden deaths in the world.
Waves of electrical activity are sent by the SA node, propagate
through the cardiac tissue and activate the mechanisms of cell
contraction, and therefore are responsible to pump blood to the body
harmonically. A spiral wave is an abnormal auto sustainable wave
that is responsible of certain types of arrhythmias. When these waves
break up, give rise to the fibrillation regime, in which there is a
complete loss in the coordination of the contraction of the heart
muscle. Interaction of spiral waves and obstacles is also of great
importance as it is believed that the attachment of a spiral wave to an
obstacle can provide with a transition of two different arrhythmias.
An obstacle can be partially excitable or non excitable. In this talk,
we present a numerical study of the interaction of meandering spiral
waves with partially and non excitable obstacles and focus on the
problem where the obstacle plays a fundamental role in the switch
between different spiral regimes, which represent different
arrhythmic regimes. Particularly, we study the phenomenon of
destabilization of spiral waves due to the presence of obstacles, a
phenomenon not completely understood (This work will appear as a
Chapter in a Book named Cardiac Arrhytmias by INTECH under the
name "Spiral Waves, Obstacles and Cardiac Arrhythmias", ISBN
979-953-307-050-5.).
Abstract: 2D/3D registration is a special case of medical image
registration which is of particular interest to surgeons. Applications
of 2D/3D registration are [1] radiotherapy planning and treatment
verification, spinal surgery, hip replacement, neurointerventions and
aortic stenting. The purpose of this paper is to provide a literature
review of the main methods for image registration for the 2D/3D
case. At the end of the paper an algorithm is proposed for 2D/3D
registration based on the Chebyssev polynomials iteration loop.
Abstract: Segmentation and quantification of stenosis is an
important task in assessing coronary artery disease. One of the main
challenges is measuring the real diameter of curved vessels.
Moreover, uncertainty in segmentation of different tissues in the
narrow vessel is an important issue that affects accuracy. This paper
proposes an algorithm to extract coronary arteries and measure the
degree of stenosis. Markovian fuzzy clustering method is applied to
model uncertainty arises from partial volume effect problem. The
algorithm employs: segmentation, centreline extraction, estimation of
orthogonal plane to centreline, measurement of the degree of
stenosis. To evaluate the accuracy and reproducibility, the approach
has been applied to a vascular phantom and the results are compared
with real diameter. The results of 10 patient datasets have been
visually judged by a qualified radiologist. The results reveal the
superiority of the proposed method compared to the Conventional
thresholding Method (CTM) on both datasets.
Abstract: Image processing for capsule endoscopy requires large
memory and it takes hours for diagnosis since operation time is
normally more than 8 hours. A real-time analysis algorithm of capsule
images can be clinically very useful. It can differentiate abnormal
tissue from health structure and provide with correlation information
among the images. Bleeding is our interest in this regard and we
propose a method of detecting frames with potential bleeding in
real-time. Our detection algorithm is based on statistical analysis and
the shapes of bleeding spots. We tested our algorithm with 30 cases of
capsule endoscopy in the digestive track. Results were excellent where
a sensitivity of 99% and a specificity of 97% were achieved in
detecting the image frames with bleeding spots.
Abstract: One of the most important causes of accidents is
driver fatigue. To reduce the accidental rate, the driver needs a
quick nap when feeling sleepy. Hence, searching for the minimum
time period of nap is a very challenging problem. The purpose of
this paper is twofold, i.e. to investigate the possible fastest time
period for nap and its relationship with stage 2 sleep, and to
develop an automatic stage 2 sleep detection and alarm device. The
experiment for this investigation is designed with 21 subjects. It
yields the result that waking up the subjects after getting into stage
2 sleep for 3-5 minutes can efficiently reduce the sleepiness.
Furthermore, the automatic stage 2 sleep detection and alarm
device yields the real-time detection accuracy of approximately
85% which is comparable with the commercial sleep lab system.
Abstract: Early detection of dementia by testing the spatial
memory can be applied using a virtual environment. This paper
presents guidelines on how to design a virtual environment
specifically for elderly in early detection of dementia. The specific
design needs to be considered because the effectiveness of the
technology relies on the ability of the end user to use it. The primary
goal of these guidelines is to promote accessibility. Based on these
guidelines, a virtual simulation was developed and evaluated. The
results on usability of acceptance and satisfaction that are tested on
young (control group) and elderly participants indicate that these
guidelines are reliable and useful for use with elderly people.
Abstract: There is an urgent need to develop novel
Mycobacterium tuberculosis (Mtb) drugs that are active against drug
resistant bacteria but, more importantly, kill persistent bacteria. Our
study structured based on integrated analysis of metabolic pathways,
small molecule screening and similarity Search in PubChem
Database. Metabolic analysis approaches based on Unified weighted
used for potent target selection. Our results suggest that pantothenate
synthetase (panC) and and 3-methyl-2-oxobutanoate hydroxymethyl
transferase (panB) as a appropriate drug targets. In our study, we
used pantothenate synthetase because of existence inhibitors. We
have reported the discovery of new antitubercular compounds
through ligand based approaches using computational tools.