Abstract: The objective of the present research manuscript is to
perform parametric, nonparametric, and decision tree analysis to
evaluate two treatments that are being used for breast cancer patients.
Our study is based on utilizing real data which was initially used in
“Tamoxifen with or without breast irradiation in women of 50 years
of age or older with early breast cancer" [1], and the data is supplied
to us by N.A. Ibrahim “Decision tree for competing risks survival
probability in breast cancer study" [2]. We agree upon certain aspects
of our findings with the published results. However, in this
manuscript, we focus on relapse time of breast cancer patients instead
of survival time and parametric analysis instead of semi-parametric
decision tree analysis is applied to provide more precise
recommendations of effectiveness of the two treatments with respect
to reoccurrence of breast cancer.
Abstract: This paper investigates the relationship between different dimensions of customer relationship management and innovation capabilities in Melli Bank of Iran. Five dimensions of CRM include information sharing, customer involvement, long-term partnership, joint problem solving and technology-based CRM are selected to measure their relationship with innovation capabilities including innovation in product, innovation in process, innovation in administrative affairs, innovation in marketing, and finally innovation in services. Research findings indicate that there is significant relationship between CRM dimensions and innovation capabilities in Melli bank of Iran.
Abstract: The flow and heat transfer characteristics for natural
convection along an inclined plate in a saturated porous medium with
an applied magnetic field have been studied. The fluid viscosity has
been assumed to be an inverse function of temperature. Assuming
temperature vary as a power function of distance. The transformed
ordinary differential equations have solved by numerical integration
using Runge-Kutta method. The velocity and temperature profile
components on the plate are computed and discussed in detail for
various values of the variable viscosity parameter, inclination angle,
magnetic field parameter, and real constant (λ). The results have also
been interpreted with the aid of tables and graphs. The numerical
values of Nusselt number have been calculated for the mentioned
parameters.
Abstract: An experiment of vented gas explosions involving two
different cylinder vessel volumes (0.2 and 0.0065 m3) was reported,
with equivalence ratio (Φ) ranged from 0.3 to 1.6. Both vessels were
closed at the rear end and fitted at the other side with a circular
orifice plate that gives a constant vent coefficient (K =Av/V2/3) of
16.4. It was shown that end ignition gives higher overpressures than
central ignition, even though most of the published work on venting
uses central ignition. For propane and ethylene, it is found that rich
mixtures gave the highest overpressures and these mixtures are not
considered in current vent design guidance; which the guideline is
based on mixtures giving the maximum flame temperature. A strong
influence of the vessel volume at constant K was found for methane,
propane, ethylene and hydrogen-air explosions. It can be concluded
that self- acceleration of the flame, which is dependent on the
distance of a flame from the ignition and the ‘suction’ at the vent
opening are significant factors affecting the vent flow during
explosion development in vented gas explosion. This additional
volume influence on vented explosions is not taken into account in
the current vent design guidance.
Abstract: This paper reports an experimental study on a sleeping
thermal manikin in a room equipped with a mixing ventilation
system. In the experimental work, heat loss from the sleeping thermal
manikin was measured under different conditions. The supply air
temperature was in a range of 17°C to 27°C. Apart from the heat loss
of the sleeping thermal manikin, the velocity distributions and
temperature distributions were also measured in the experiments for
subsequent analysis.
Abstract: The aim of the present investigation was to compare
sex differences in thyroid gland structure of rabbits. Five adult male
and five adult female (3.1-3.5 kg body weight) New Zealand white
rabbits were used in the experiment. Results showed that at light
microscopic level, there was no sex difference in microscopic
appearance of the thyroid glands. At electron microscopic level,
however, the mitochondria and the microvilli of the follicular cells
are more numerous and the Golgi complex is also more extensive in
male rabbits in comparison to females. Results obtained from
micrometric measurements showed that the volume density of the
follicles is higher in males than in females, but the differences are not
statistically significant .The volume density of epithelium and the
height of follicular cells are significantly greater in males than in
females and reverse is true about the volume density of interstitium
(p
Abstract: Circular tubes have been widely used as structural
members in engineering application. Therefore, its collapse behavior
has been studied for many decades, focusing on its energy absorption
characteristics. In order to predict the collapse behavior of members,
one could rely on the use of finite element codes or experiments.
These tools are helpful and high accuracy but costly and require
extensive running time. Therefore, an approximating model of tubes
collapse mechanism is an alternative for early step of design. This
paper is also aimed to develop a closed-form solution of thin-walled
circular tube subjected to bending. It has extended the Elchalakani et
al.-s model (Int. J. Mech. Sci.2002; 44:1117-1143) to include the
rate of energy dissipation of rolling hinge in the circumferential
direction. The 3-D geometrical collapse mechanism was analyzed by
adding the oblique hinge lines along the longitudinal tube within the
length of plastically deforming zone. The model was based on the
principal of energy rate conservation. Therefore, the rates of internal
energy dissipation were calculated for each hinge lines which are
defined in term of velocity field. Inextensional deformation and
perfect plastic material behavior was assumed in the derivation of
deformation energy rate. The analytical result was compared with
experimental result. The experiment was conducted with a number of
tubes having various D/t ratios. Good agreement between analytical
and experiment was achieved.
Abstract: The present work describes an experimental
investigation concerning the determination of viscosity behavior with
shear rate and temperature of edible oils: canola; sunflower; corn;
soybean and the no edible oil: Jatropha curcas. Besides these, it was
tested a blend of canola, corn and sunflower oils as well as sunflower
and soybean biodiesel. Based on experiments, it was obtained shear
stress and viscosity at different shear rates of each sample at 40ºC, as
well as viscosity of each sample at various temperatures in the range
of 24 to 85ºC. Furthermore, it was compared the curves obtained for
the viscosity versus temperature with the curves obtained by
modeling the viscosity dependency on temperature using the Vogel
equation. Also a test in a stationary engine was performed in order to
study the energy generation using blends of soybean oil and soybean
biodiesel with diesel.
Abstract: The product development process (PDP) in the
Technology group plays a very important role in the launch of any
product. While a manufacturing process encourages the use of certain
measures to reduce health, safety and environmental (HSE) risks on
the shop floor, the PDP concentrates on the use of Geometric
Dimensioning and Tolerancing (GD&T) to develop a flawless design.
Furthermore, PDP distributes and coordinates activities between
different departments such as marketing, purchasing, and
manufacturing. However, it is seldom realized that PDP makes a
significant contribution to developing a product that reduces HSE
risks by encouraging the Technology group to use effective GD&T.
The GD&T is a precise communication tool that uses a set of
symbols, rules, and definitions to mathematically define parts to be
manufactured. It is a quality assurance method widely used in the oil
and gas sector. Traditionally it is used to ensure the
interchangeability of a part without affecting its form, fit, and
function. Parts that do not meet these requirements are rejected
during quality audits.
This paper discusses how the Technology group integrates this
quality assurance tool into the PDP and how the tool plays a major
role in helping the HSE department in its goal towards eliminating
HSE incidents. The PDP involves a thorough risk assessment and
establishes a method to address those risks during the design stage.
An illustration shows how GD&T helped reduce safety risks by
ergonomically improving assembling operations. A brief discussion
explains how tolerances provided on a part help prevent finger injury.
This tool has equipped Technology to produce fixtures, which are
used daily in operations as well as manufacturing. By applying
GD&T to create good fits, HSE risks are mitigated for operating
personnel. Both customers and service providers benefit from
reduced safety risks.
Abstract: Providing Services at Home has become over the last
few years a very dynamic and promising technological domain. It is
likely to enable wide dissemination of secure and automated living
environments. We propose a methodology for identifying threats to
Services at Home Delivery systems, as well as a threat analysis
of a multi-provider Home Gateway architecture. This methodology
is based on a dichotomous positive/preventive study of the target
system: it aims at identifying both what the system must do, and
what it must not do. This approach completes existing methods with
a synthetic view of potential security flaws, thus enabling suitable
measures to be taken into account. Security implications of the
evolution of a given system become easier to deal with. A prototype
is built based on the conclusions of this analysis.
Abstract: Bionanotechnology deals with nanoscopic interactions between nanostructured materials and biological systems. Polymer nanocomposites with optimized biological activity have attracted great attention. Nanoclay is considered as reinforcing nanofiller in manufacturing of high performance nanocomposites. In current study, organomodified-nanoclay with negatively charged silicate layers was incorporated into biomedical grade silicone rubber. Nanoparticle loading has been tailored to enhance cell behavior. Addition of nanoparticles led to improved mechanical properties of substrate with enhanced strength and stiffness while no toxic effects was observed. Results indicated improved viability and proliferation of cells by addition of nanofillers. The improved mechanical properties of the matrix result in proper cell response through adjustment and arrangement of cytoskeletal fibers. Results can be applied in tissue engineering when enhanced substrates are required for improvement of cell behavior for in vivo applications.
Abstract: In this study, we present an advanced detection
technique for mass type breast cancer based on texture information
of organs. The proposed method detects the cancer areas in three
stages. In the first stage, the midpoints of mass area are determined
based on AHE (Adaptive Histogram Equalization). In the second
stage, we set the threshold coefficient of homogeneity by using
MLE (Maximum Likelihood Estimation) to compute the uniformity
of texture. Finally, mass type cancer tissues are extracted from the
original image. As a result, it was observed that the proposed
method shows an improved detection performance on dense breast
tissues of Korean women compared with the existing methods. It is
expected that the proposed method may provide additional
diagnostic information for detection of mass-type breast cancer.
Abstract: The hydrodynamic processes in bubbly liquid flowing
in tubes and nozzles are studied theoretically and numerically. The
principal regularities of non-stationary processes of boiling liquid
outflow are established under conditions of experiments when the
depressurization of a tube with high pressure inside occurs. The
steady-state solution of bubbly liquid flow in the nozzle of round
cross section with high pressure and temperature conditions inside
bubbles is studied accounting for phase transition and chemical
reactions.
Abstract: Nigella sativa L. is an aromatic plant belonging to the
family Ranunculaceae. It has been used traditionally, especially in the
middle East and India, for the treatment of asthma, cough, bronchitis,
headache, rheumatism, fever, influenza and eczema. Several
biological activities have been reported in Nigella sativa seeds,
including antioxidant. In this context we tried to estimate the
antioxidant activity of various extracts prepared from Nigella sativa
seeds, methanolic extract (ME), chloroformic extract (CE), hexanic
extract (HE : fixed oil), ethyl acetate extract (EAE) water extract
(WE). The Folin-Ciocalteu assay showed that CE and EAE contained
high level of phenolic compounds 81.31 and 72.43μg GAE/mg of
extract respectively. Similarly, the CE and EAE exhibited the highest
DPPH radical scavenging activity, with IC50 values of 106.56μg/ml
and 121.62μg/ml respectively. In addition, CE and HE showed the
most scavenging activity against superoxide radical generated in the
PMS-NADH-NBT system with respective IC50 values of 361.86
μg/ml and 371.80 μg/ml, which is comparable to the activity of the
standard antioxidant BHT (344.59 μg/ml). Ferrous ion chelating
capacity assay showed that WE, EAE and ME are the most active
with 40.57, 39.70 and 22.02 mg EDTA-E/g of extract. The inhibition
of linoleic acid/ß-carotene coupled oxidation was estimated by ßcarotene
bleaching assay, this showed a highest relative antioxidant
activity with CE and EAE (69.82% of inhibition). The antioxidant
activities of the methanolic extract and the fixed oil are confirmed by
an in vivo assay in mice, the daily oral administration of methanolic
extract (500 and 800 mg/kg/day) and fixed oil (2 and 4 ml/kg/day)
during 21 days, resulted in a significant enhancement of the blood
total antioxidant capacity (measured by KRL test) and the plasmatic
antioxidant capacity towards DPPH radical.
Abstract: Databases have become ubiquitous. Almost all IT applications are storing into and retrieving information from databases. Retrieving information from the database requires knowledge of technical languages such as Structured Query Language (SQL). However majority of the users who interact with the databases do not have a technical background and are intimidated by the idea of using languages such as SQL. This has led to the development of a few Natural Language Database Interfaces (NLDBIs). A NLDBI allows the user to query the database in a natural language. This paper highlights on architecture of new NLDBI system, its implementation and discusses on results obtained. In most of the typical NLDBI systems the natural language statement is converted into an internal representation based on the syntactic and semantic knowledge of the natural language. This representation is then converted into queries using a representation converter. A natural language query is translated to an equivalent SQL query after processing through various stages. The work has been experimented on primitive database queries with certain constraints.
Abstract: The interdependences among stock market indices
were studied for a long while by academics in the entire world. The
current financial crisis opened the door to a wide range of opinions
concerning the understanding and measurement of the connections
considered to provide the controversial phenomenon of market
integration. Using data on the log-returns of 17 stock market indices
that include most of the CEE markets, from 2005 until 2009, our
paper studies the problem of these dependences using a new
methodological tool that takes into account both the volatility
clustering effect and the stochastic properties of these linkages
through a Dynamic Conditional System of Simultaneous Equations.
We find that the crisis is well captured by our model as it provides
evidence for the high volatility – high dependence effect.
Abstract: The density estimates considered in this paper comprise
a base density and an adjustment component consisting of a linear
combination of orthogonal polynomials. It is shown that, in the
context of density approximation, the coefficients of the linear combination
can be determined either from a moment-matching technique
or a weighted least-squares approach. A kernel representation of
the corresponding density estimates is obtained. Additionally, two
refinements of the Kronmal-Tarter stopping criterion are proposed
for determining the degree of the polynomial adjustment. By way of
illustration, the density estimation methodology advocated herein is
applied to two data sets.
Abstract: Nuts are part of a healthy diet such as Mediterranean diet. Benefits of nuts in reducing the risk of heart disease has been reasonably attributed to their composition of vitamins, minerals, unsaturated fatty acids, fiber and phytochemicals such as polyphenols, tocopherols, squalene and phytosterols. More than 75% of total fatty acids of nuts are unsaturated. α- tocopherol is the main tocopherol isomer present in most of the nuts. While walnuts, Brazil nut, cashew nut, peanut, pecan and pistachio nuts are rich in γ- tocopherol. β- sitosterol is dominant sterol in nuts. Pistachio and pine nut have the highest total phytosterol and Brazil nut and English walnut the lowest. Walnuts also contain large amount of phenolic compounds compared with other nuts. Nuts are rich in compounds with antioxidant properties and their consumption can offer preventing from incidence of many diseases including cardiovascular.
Abstract: Equilibrium and rate based models have been applied
in the simulation of methyl tertiary-butyl ether (MTBE) synthesis
through reactive distillation. Temperature and composition profiles
were compared for both the models and found that both the profiles
trends, though qualitatively similar are significantly different
quantitatively. In the rate based method (RBM), multicomponent
mass transfer coefficients have been incorporated to describe
interphase mass transfer. MTBE mole fraction in the bottom stream is
found to be 0.9914 in the Equilibrium Model (EQM) and only 0.9904
for RBM when the same column configuration was preserved. The
individual tray efficiencies were incorporated in the EQM and
simulations were carried out. Dynamic simulation have been also
carried out for the two column configurations and compared.
Abstract: MMR vaccine failure had been reported globally and
here we report that it occurs now in India. Samples were collected from clinically suspected mumps cases were subjected for anti
mumps antibodies, virus isolation, RT-PCR, sequencing and
phylogenetic tree analysis. 56 samples collected from men and women belonging to various age groups. 30 had been vaccinated and
the status of 26 patients was unknown. 28 out of 30 samples were
found to be symptomatic and positive for Mumps IgM, indicating
active mumps infection in 93.4% of the vaccinated population. A
phylogenetic tree comparison of the clinical isolate is shown to be genotype C which is distinct from vaccine strain. Our study clearly sending warning signs that MMR vaccine is a failure and it needs to be revamped for the human use by increasing its efficacy and efficiency.