Abstract: Leonotisleonurus a shrub indigenous to Southern
Africa is widely used in traditional medicine to treat a variety of
conditions ranging from skin diseases and cough to epileptic fits and
‘heart problems’. Studies on the aqueous extract of the leaves have
indicated cycloxegenase enzyme inhibitory activity and an
antihypertensive effect.
Five methanol leaf extract fractions (MLEa - MLEe) of L.
leonurus were tested on anaesthetized normotensive male Wistar rats
(AWR) and isolated perfused working rat hearts (IWH). Fraction
MLEc (0.01mg/kg – 0.05mg/kg) induced significant increases in BP
and HR in AWR and positive chronotropic and inotropic effects in
IWH (1.0mg/ml – 5.0mg/ml). Pre-administration of atenolol
(2.0mg/kg) and prazosin (60μg/kg) significantly inhibited MLEc
effect on HR and MAP respectively in vivo, while atenolol
(7.0mg/ml) pre-perfusion significantly inhibited MLEc effect in vitro.
The hypertensive effect of MLEc is probably via β1agonism.
Results also indicate the presence of multiple cardioactive
compounds in L. leonurus.
Abstract: Ultra-low-power (ULP) circuits have received
widespread attention due to the rapid growth of biomedical
applications and Battery-less Electronics. Subthreshold region of
transistor operation is used in ULP circuits. Major research challenge
in the subthreshold operating region is to extract the ULP benefits
with minimal degradation in speed and robustness. Process, Voltage
and Temperature (PVT) variations significantly affect the
performance of subthreshold circuits. Designed performance
parameters of ULP circuits may vary largely due to temperature
variations. Hence, this paper investigates the effect of temperature
variation on device and circuit performance parameters at different
biasing voltages in the subthreshold region. Simulation results clearly
demonstrate that in deep subthreshold and near threshold voltage
regions, performance parameters are significantly affected whereas in
moderate subthreshold region, subthreshold circuits are more
immune to temperature variations. This establishes that moderate
subthreshold region is ideal for temperature immune circuits.
Abstract: The dynamic or complex modulus test is considered
to be a mechanistically based laboratory test to reliably characterize
the strength and load-resistance of Hot-Mix Asphalt (HMA) mixes
used in the construction of roads. The most common observation is
that the data collected from these tests are often noisy and somewhat
non-sinusoidal. This hampers accurate analysis of the data to obtain
engineering insight. The goal of the work presented in this paper is to
develop and compare automated evolutionary computational
techniques to filter test noise in the collection of data for the HMA
complex modulus test. The results showed that the Covariance
Matrix Adaptation-Evolutionary Strategy (CMA-ES) approach is
computationally efficient for filtering data obtained from the HMA
complex modulus test.
Abstract: Educational institutions often implement policies with
the intention of influencing how learning and teaching occur.
Generally, such policies are not as effective as their makers would
like; changing the behavior of third-level teachers proves difficult.
Nevertheless, a policy instituted in 2006 at the Dublin Institute of
Technology has met with success: each newly hired faculty member
must have a post-graduate qualification in “Learning and Teaching"
or successfully complete one within the first two years of
employment. The intention is to build teachers- knowledge about
student-centered pedagogies and their capacity to implement them.
As a result of this policy (and associated programs that support it),
positive outcomes are readily apparent. Individual teachers who have
completed the programs have implemented significant change at the
course and program levels. This paper introduces the policy,
identifies outcomes in relation to existing theory, describes research
underway, and pinpoints areas where organizational learning has
occurred.
Abstract: This paper discusses two observers, which are used
for the estimation of parameters of PMSM. Former one, reduced
order observer, which is used to estimate the inaccessible parameters
of PMSM. Later one, full order observer, which is used to estimate
all the parameters of PMSM even though some of the parameters are
directly available for measurement, so as to meet with the
insensitivity to the parameter variation. However, the state space
model contains some nonlinear terms i.e. the product of different
state variables. The asymptotic state observer, which approximately
reconstructs the state vector for linear systems without uncertainties,
was presented by Luenberger. In this work, a modified form of such
an observer is used by including a non-linear term involving the
speed. So, both the observers are designed in the framework of
nonlinear control; their stability and rate of convergence is discussed.
Abstract: Explosive welding is a process which uses explosive
detonation to move the flyer plate material into the base material to
produce a solid state joint. Experimental tests have been carried out
by other researchers; have been considered to explosively welded
aluminium 7039 and steel 4340 tubes in one step. The tests have been
done using various stand-off distances and explosive ratios. Various
interface geometries have been obtained from these experiments. In
this paper, all the experiments carried out were simulated using the
finite element method. The flyer plate and collision velocities
obtained from the analysis were validated by the pin-measurement
experiments. The numerical results showed that very high localized
plastic deformation produced at the bond interface. The
Ls_dyna_971 FEM has been used for all simulation process.
Abstract: Urinary Tract Infections (UTI) account for an estimated 25-40% nosocomial infection, out of which 90% are associated with urinary catheter, called Catheter associated urinary tract infection (CAUTI). The microbial populations within CAUTI frequently develop as biofilms. In the present study, microbial contamination of indwelling urinary catheters was investigated. Biofilm forming ability of the isolates was determined by tissue culture plate method. Prevention of biofilm formation in the urinary catheter by Pseudomonas aeruginosa was also determined by coating the catheter with some enzymes, gentamycin and EDTA. It was found that 64% of the urinary catheters get contaminated during the course of catheterization. Of the total 6 isolates, biofilm formation was seen in 100% Pseudomonas aeruginosa and E. coli, 90% in Enterococci, 80% in Klebsiella and 66% in S. aureus. It was noted that the biofilm production by Pseudomonas was prolonged by 7 days in amylase, 8 days in protease, 6 days in lysozyme, 7days in gentamycin and 5 days in EDTA treated catheter.
Abstract: Grid computing is growing rapidly in the distributed
heterogeneous systems for utilizing and sharing large-scale resources
to solve complex scientific problems. Scheduling is the most recent
topic used to achieve high performance in grid environments. It aims
to find a suitable allocation of resources for each job. A typical
problem which arises during this task is the decision of scheduling. It
is about an effective utilization of processor to minimize tardiness
time of a job, when it is being scheduled. This paper, therefore,
addresses the problem by developing a general framework of grid
scheduling using dynamic information and an ant colony
optimization algorithm to improve the decision of scheduling. The
performance of various dispatching rules such as First Come First
Served (FCFS), Earliest Due Date (EDD), Earliest Release Date
(ERD), and an Ant Colony Optimization (ACO) are compared.
Moreover, the benefit of using an Ant Colony Optimization for
performance improvement of the grid Scheduling is also discussed. It
is found that the scheduling system using an Ant Colony
Optimization algorithm can efficiently and effectively allocate jobs
to proper resources.
Abstract: Extraction of edge-end-pixels is an important step for the edge linking process to achieve edge-based image segmentation. This paper presents an algorithm to extract edge-end pixels together with their directional sensitivities as an augmentation to the currently available mathematical models. The algorithm is implemented in the Java environment because of its inherent compatibility with web interfaces since its main use is envisaged to be for remote image analysis on a virtual instrumentation platform.
Abstract: This paper considers the autonomous navigation
problem of multiple n-link nonholonomic mobile manipulators within
an obstacle-ridden environment. We present a set of nonlinear
acceleration controllers, derived from the Lyapunov-based control
scheme, which generates collision-free trajectories of the mobile
manipulators from initial configurations to final configurations in a
constrained environment cluttered with stationary solid objects of
different shapes and sizes. We demonstrate the efficiency of the
control scheme and the resulting acceleration controllers of the
mobile manipulators with results through computer simulations of an
interesting scenario.
Abstract: Un-doped GaN film of thickness 1.90 mm, grown on
sapphire substrate were uniformly implanted with 325 keV Mn+ ions
for various fluences varying from 1.75 x 1015 - 2.0 x 1016 ions cm-2 at
3500 C substrate temperature. The structural, morphological and
magnetic properties of Mn ion implanted gallium nitride samples
were studied using XRD, AFM and SQUID techniques. XRD of the
sample implanted with various ion fluences showed the presence of
different magnetic phases of Ga3Mn, Ga0.6Mn0.4 and Mn4N.
However, the compositions of these phases were found to be
depended on the ion fluence. AFM images of non-implanted sample
showed micrograph with rms surface roughness 2.17 nm. Whereas
samples implanted with the various fluences showed the presence of
nano clusters on the surface of GaN. The shape, size and density of
the clusters were found to vary with respect to ion fluence. Magnetic
moment versus applied field curves of the samples implanted with
various fluences exhibit the hysteresis loops. The Curie temperature
estimated from zero field cooled and field cooled curves for the
samples implanted with the fluence of 1.75 x 1015, 1.5 x 1016 and 2.0
x 1016 ions cm-2 was found to be 309 K, 342 K and 350 K
respectively.
Abstract: A neurofuzzy approach for a given set of input-output training data is proposed in two phases. Firstly, the data set is partitioned automatically into a set of clusters. Then a fuzzy if-then rule is extracted from each cluster to form a fuzzy rule base. Secondly, a fuzzy neural network is constructed accordingly and parameters are tuned to increase the precision of the fuzzy rule base. This network is able to learn and optimize the rule base of a Sugeno like Fuzzy inference system using Hybrid learning algorithm, which combines gradient descent, and least mean square algorithm. This proposed neurofuzzy system has the advantage of determining the number of rules automatically and also reduce the number of rules, decrease computational time, learns faster and consumes less memory. The authors also investigate that how neurofuzzy techniques can be applied in the area of control theory to design a fuzzy controller for linear and nonlinear dynamic systems modelling from a set of input/output data. The simulation analysis on a wide range of processes, to identify nonlinear components on-linely in a control system and a benchmark problem involving the prediction of a chaotic time series is carried out. Furthermore, the well-known examples of linear and nonlinear systems are also simulated under the Matlab/Simulink environment. The above combination is also illustrated in modeling the relationship between automobile trips and demographic factors.
Abstract: There are many automotive accidents due to blind spots and driver inattentiveness. Blind spot is the area that is invisible to the driver's viewpoint without head rotation. Several methods are available for assisting the drivers. Simplest methods are — rear mirrors and wide-angle lenses. But, these methods have a disadvantage of the requirement for human assistance. So, the accuracy of these devices depends on driver. Another approach called an automated approach that makes use of sensors such as sonar or radar. These sensors are used to gather range information. The range information will be processed and used for detecting the collision. The disadvantage of this system is — low angular resolution and limited sensing volumes. This paper is a panoramic sensor based automotive vehicle monitoring..
Abstract: The mechanical properties of granular solids are
dependent on the flow of stresses from one particle to another
through inter-particle contact. Although some experimental methods
have been used to study the inter-particle contacts in the past,
preliminary work with these techniques indicated that they do not
have the necessary resolution to distinguish between those contacts
that transmit the load and those that do not, especially for systems
with a wide distribution of particle sizes. In this research, computer
simulations are used to study the nature and distribution of contacts
in a compact with wide particle size distribution, representative of
aggregate size distribution used in asphalt pavement construction.
The packing fraction, the mean number of contacts and the
distribution of contacts were studied for different scenarios. A
methodology to distinguish and compute the fraction of load-bearing
particles and the fraction of space-filling particles (particles that do
not transmit any force) is needed for further investigation.
Abstract: A numerical study is presented on buckling and post
buckling behaviour of laminated carbon fiber reinforced plastic
(CFRP) thin-walled cylindrical shells under axial compression using
asymmetric meshing technique (AMT). Asymmetric meshing
technique is a perturbation technique to introduce disturbance without
changing geometry, boundary conditions or loading conditions.
Asymmetric meshing affects predicted buckling load, buckling mode
shape and post-buckling behaviour. Linear (eigenvalue) and nonlinear
(Riks) analyses have been performed to study the effect of
asymmetric meshing in the form of a patch on buckling behaviour.
The reduction in the buckling load using Asymmetric meshing
technique was observed to be about 15%. An isolated dimple formed
near the bifurcation point and the size of which increased to reach a
stable state in the post-buckling region. The load-displacement curve
behaviour applying asymmetric meshing is quite similar to the curve
obtained using initial geometric imperfection in the shell model.
Abstract: Type 2 diabetes mellitus (T2DM) is a complex
metabolic disorder that characterized by the presence of high glucose
in blood that cause from insulin resistance and insufficiency due to
deterioration β-cell Langerhans functions. T2DM is commonly
caused by the combination of inherited genetic variations as well as
our own lifestyle. Metallothionein (MT) is a known cysteine-rich
protein responsible in helping zinc homeostasis which is important in
insulin signaling and secretion as well as protection our body from
reactive oxygen species (ROS). MT scavenged ROS and free
radicals in our body happen to be one of the reasons of T2DM and its
complications. The objective of this study was to investigate the
association of MT1A and MT2A polymorphisms between T2DM and
control subjects among Malay populations. This study involved 150
T2DM and 120 Healthy individuals of Malay ethnic with mixed
genders. The genomic DNA was extracted from buccal cells and
amplified for MT1A and MT2A loci; the 347bp and 238bp banding
patterns were respectively produced by mean of the Polymerase
Chain Reaction (PCR). The PCR products were digested with Mlucl
and Tsp451 restriction enzymes respectively and producing
fragments lengths of (158/189/347bp) and (103/135/238bp)
respectively. The ANOVA test was conducted and it shown that there
was a significant difference between diabetic and control subjects for
age, BMI, WHR, SBP, FPG, HBA1C, LDL, TG, TC and family
history with (P0.05). The genotype
frequency for AA, AG and GG of MT1A polymorphisms was 72.7%,
22.7% and 4.7% in cases and 15%, 55% and 30% in control
respectively. As for MT2A, genotype frequency of GG, GC and CC
was 42.7%, 27.3% and 30% in case and 5%, 40% and 55% for
control respectively. Both polymorphisms show significant difference
between two investigated groups with (P=0.000). The Post hoc test
was conducted and shows a significant difference between the
genotypes within each polymorphism (P=0. 000). The MT1A and
MT2A polymorphisms were believed to be the reliable molecular
markers to distinguish the T2DM subjects from healthy individuals in
Malay populations.
Abstract: Cameras are often mounted on platforms that canmove like rovers, booms, gantries and aircraft. People operate suchplatforms to capture desired views of scene or target. To avoidcollisions with the environment and occlusions, such platforms oftenpossess redundant degrees-of-freedom. As a result, manipulatingsuch platforms demands much skill. Visual-servoing some degrees-of-freedom may reduce operator burden and improve tracking per-formance. This concept, which we call human-in-the-loop visual-servoing, is demonstrated in this paper and applies a Α-β-γ filter and feedforward controller to a broadcast camera boom.
Abstract: Proximate (moisture, protein, total fat, total ash) and mineral (K, P, Na, Mg, Ca, Zn, Fe, Cu and Mn) composition of chicken giblets (heart, liver and gizzard) were investigated. Phosphorous content, as well as proximate composition, were determined according to recommended ISO methods. The content of all elements, except phosphorus, of the giblets tissues were determined using inductively coupled plasma-optical emission spectrometry (ICP-OES), after dry ashing mineralization. Regarding proximate composition heart was the highest in total fat content, and the lowest in protein content. Liver was the highest in protein and total ash content, while gizzard was the highest in moisture and the lowest in total fat content. Regarding mineral composition liver was the highest for K, P, Ca, Mg, Fe, Zn, Cu, and Mn, while heart was the highest for Na content. The contents of almost all investigated minerals in analysed giblets tissues of chickens from Vojvodina were similar to values reported in the literature, i.e. in national food composition databases of other countries.
Abstract: The study of the variability of the postural strategies
in low back pain patients, as a criterion in evaluation of the
adaptability of this system to the environmental demands is the
purpose of this study. A cross-sectional case-control study was
performed on 21 recurrent non-specific low back pain patients and 21
healthy volunteers. The electromyography activity of Deltoid,
External Oblique (EO), Transverse Abdominis/Internal Oblique
(TrA/IO) and Erector Spine (ES) muscles of each person was
recorded in 75 rapid arm flexion with maximum acceleration.
Standard deviation of trunk muscles onset relative to deltoid muscle
onset were statistically analyzed by MANOVA . The results show
that chronic low back pain patients exhibit less variability in their
anticipatory postural adjustments (APAs) in comparison with the
control group. There is a decrease in variability of postural control
system of recurrent non-specific low back pain patients that can
result in the persistence of pain and chronicity by decreasing the
adaptability to environmental demands.
Abstract: The paper proposes a novel technique for iris
recognition using texture and phase features. Texture features are
extracted on the normalized iris strip using Haar Wavelet while phase
features are obtained using LOG Gabor Wavelet. The matching
scores generated from individual modules are combined using sum of
score technique. The system is tested on database obtained from Bath
University and Indian Institute of Technology Kanpur and is giving
an accuracy of 95.62% and 97.66% respectively. The FAR and FRR
of the combined system is also reduced comparatively.