Abstract: Morphogenesis is the process that underpins the selforganised development and regeneration of biological systems. The ability to mimick morphogenesis in artificial systems has great potential for many engineering applications, including production of biological tissue, design of robust electronic systems and the co-ordination of parallel computing. Previous attempts to mimick these complex dynamics within artificial systems have relied upon the use of evolutionary algorithms that have limited their size and complexity. This paper will present some insight into the underlying dynamics of morphogenesis, then show how to, without the assistance of evolutionary algorithms, design cellular architectures that converge to complex patterns.
Abstract: Emerging Bio-engineering fields such as Brain
Computer Interfaces, neuroprothesis devices and modeling and
simulation of neural networks have led to increased research activity
in algorithms for the detection, isolation and classification of Action
Potentials (AP) from noisy data trains. Current techniques in the field
of 'unsupervised no-prior knowledge' biosignal processing include
energy operators, wavelet detection and adaptive thresholding. These
tend to bias towards larger AP waveforms, AP may be missed due to
deviations in spike shape and frequency and correlated noise
spectrums can cause false detection. Also, such algorithms tend to
suffer from large computational expense.
A new signal detection technique based upon the ideas of phasespace
diagrams and trajectories is proposed based upon the use of a
delayed copy of the AP to highlight discontinuities relative to
background noise. This idea has been used to create algorithms that
are computationally inexpensive and address the above problems.
Distinct AP have been picked out and manually classified from
real physiological data recorded from a cockroach. To facilitate
testing of the new technique, an Auto Regressive Moving Average
(ARMA) noise model has been constructed bases upon background
noise of the recordings. Along with the AP classification means this
model enables generation of realistic neuronal data sets at arbitrary
signal to noise ratio (SNR).