Abstract: In this paper we introduce a novel method for
the characterization of synchronziation and coupling effects
in multivariate time series that can be used for the analysis
of EEG or ECoG signals recorded during epileptic seizures.
The method allows to visualize the spatio-temporal evolution
of synchronization and coupling effects that are characteristic
for epileptic seizures. Similar to other methods proposed for
this purpose our method is based on a regression analysis.
However, a more general definition of the regression together
with an effective channel selection procedure allows to use the
method even for time series that are highly correlated, which
is commonly the case in EEG/ECoG recordings with large
numbers of electrodes. The method was experimentally tested
on ECoG recordings of epileptic seizures from patients with
temporal lobe epilepsies. A comparision with the results from
a independent visual inspection by clinical experts showed
an excellent agreement with the patterns obtained with the
proposed method.