Abstract: The purpose of this work is to develop a mathematical
model of Human Cardiovascular System using lumped parameter
method. The model is divided in three parts: Systemic Circulation,
Pulmonary Circulation and the Heart. The established mathematical
model has been simulated by MATLAB software. The innovation of
this study is in describing the system based on the vessel diameters
and simulating mathematical equations with active electrical
elements. Terminology of human physical body and required
physical data like vessel’s radius, thickness etc., which are required
to calculate circuit parameters like resistance, inductance and
capacitance, are proceeds from well-known medical books. The
developed model is useful to understand the anatomic of human
cardiovascular system and related syndromes. The model is deal with
vessel’s pressure and blood flow at certain time.