Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: The aim of this paper is to create a proposal for determining the costs of logistics processes by using process-oriented calculation methods. The traditional approach is that logistics costs are part of manufacturing overhead which is usually calculated as a percentage surcharge. Therefore in the traditional approach it is not obvious where and in which activities costs were incurred. So it is impossible to trace logistics costs to products. Our point of view is trying to fix or at least improve this issue. Another benefit of applying the process approach is identification of logistics processes which are otherwise part of manufacturing overhead. In the first part this paper describes the development of process-oriented methods over time. The next part shows the possibility of implementing the process-oriented method called Prozesskostenrechnung to logistics processes. The conclusion summarizes advantages and disadvantages of using this method in logistics.
Abstract: The expanded Invasive Weed Optimization algorithm (exIWO) is an optimization metaheuristic modelled on the original IWO version created by the researchers from the University of Tehran. The authors of the present paper have extended the exIWO algorithm introducing a set of both deterministic and non-deterministic strategies of individuals’ selection. The goal of the project was to evaluate the exIWO by testing its usefulness for solving some test instances of the traveling salesman problem (TSP) taken from the TSPLIB collection which allows comparing the experimental results with optimal values.
Abstract: This paper deals with a proposal of a new
methodology for durability assessment of solidification product for
its safe further use. The new methodology is based on a review of the
current state of assessment of treated waste in Czech Republic and
abroad. The aim of the paper is to propose an optimal evaluation
methodology for verifying properties of solidification product to
ensure its safe further use in building industry.
Abstract: Both knowledge economy and sustainable development are considered key dimensions in the policy action lines of many developed and developing countries. In this context, universities and other higher education institutes have a vital role in developing and sustaining wellbeing communities.
In this paper, the authors’ aim is to address the links between the concepts of innovation and entrepreneurial capacity and knowledge economy, and to utilize the approach of intellectual capital development in building a sustainable knowledge economy.
The paper will contribute to two discourses:
Developing a common understanding of the intersection aspects between the three concepts: Knowledge economy, Innovation and entrepreneurial system, and sustainable development.
Paving the road towards developing an integrated multidimensional framework for sustainable knowledge economy.
Abstract: Lately, with the increasing number of location-based applications, demand for highly accurate and reliable indoor localization became urgent. This is a challenging problem, due to the measurement variance which is the consequence of various factors like obstacles, equipment properties and environmental changes in complex nature of indoor environments. In this paper we propose low-cost custom-setup infrastructure solution and localization algorithm based on the Weighted Centroid Localization (WCL) method. Localization accuracy is increased by several enhancements: calibration of RSSI values gained from wireless nodes, repetitive measurements of RSSI to exclude deviating values from the position estimation, and by considering orientation of the device according to the wireless nodes. We conducted several experiments to evaluate the proposed algorithm. High accuracy of ~1m was achieved.
Abstract: Nowadays spinal deformities are very frequent
problems among teenagers. Scheuermann disease is a one
dimensional deformity of the spine, but it has prevalence over 11% of
the children. A traditional technology, the moiré method was used by
us for screening and diagnosing this type of spinal deformity. A
LabVIEW program has been developed to evaluate the moiré pictures
of patients with Scheuermann disease. Two different solutions were
tested in this computer program, the extreme and the inflexion point
calculation methods. Effects using these methods were compared and
according to the results both solutions seemed to be appropriate.
Statistical results showed better efficiency in case of the extreme
search method where the average difference was only 6,09⁰.
Abstract: Many problems are occurred in watershed due to human activity and economic development. The purpose is to determine the effects of the land use change on surface runoff using land use map on 1980, 2001 and 2008 and daily weather data during January 1, 1979 to September 30, 2010 applied to SWAT. The results can be presented that the polynomial equation is suitable to display that relationship. These equations for land use in 1980, 2001 and 2008 are consisted of y = -0.0076x5 + 0.1914x4–1.6386x3 + 6.6324x2–8.736x + 7.8023(R2 = 0.9255), y = -0.0298x5 + 0.8794x4 - 9.8056x3 + 51.99x2 - 117.04x + 96.797; (R2 = 0.9186) and y = -0.0277x5 + 0.8132x4 - 8.9598x3 + 46.498x2–101.83x +81.108 (R2 = 0.9006), respectively. Moreover, if the agricultural area is the largest area, it is a sensitive parameter to concern surface runoff.
Abstract: The climate change is a main parameter which affects the element of hydrological cycle especially runoff. Then, the purpose of this study is to determine the impact of the climate change on surface runoff using land use map on 2008 and daily weather data during January 1, 1979 to September 30, 2010 for SWAT model. SWAT continuously simulate time model and operates on a daily time step at basin scale. The results present that the effect of temperature change cannot be clearly presented on the change of runoff while the rainfall, relative humidity and evaporation are the parameters for the considering of runoff change. If there are the increasing of rainfall and relative humidity, there is also the increasing of runoff. On the other hand, if there is the increasing of evaporation, there is the decreasing of runoff.
Abstract: The paper reports on the subject of recycling and
further use of secondary raw materials obtained from solar panels,
which is becoming a very up to date topic in recent years. Recycling
these panels is very difficult and complex, and the use of resulting
secondary raw materials is still not fully resolved. Within the
research carried out at the Brno University of Technology, new
polymer materials used for industrial floors are being developed.
Secondary raw materials are incorporated into these polymers as
fillers. One of the tested filler materials was glass obtained from solar
panels. The following text describes procedures and results of the
tests that were performed on these materials, confirming the
possibility of the use of solar panel glass in industrial polymer
flooring systems.
Abstract: The lignite-fired power plants in the Western Macedonia Lignite Center produce more than 8106 t of fly ash per year. Approximately 90% of this quantity is used for restoration-reclamation of exhausted open-cast lignite mines and slope stabilization of the overburden. The purpose of this work is to evaluate the environmental behavior of the mixture of waste rock and fly ash that is being used in the external deposition site of the South Field lignite mine. For this reason, a borehole was made within the site and 86 samples were taken and subjected to chemical analyses and leaching tests. The results showed very limited leaching of trace elements and heavy metals from this mixture. Moreover, when compared to the limit values set for waste acceptable in inert waste landfills, only few excesses were observed, indicating only minor risk for groundwater pollution. However, due to the complexity of both the leaching process and the contaminant pathway, more boreholes and analyses should be made in nearby locations and a systematic groundwater monitoring program should be implemented both downstream and within the external deposition site.
Abstract: This study analyzed and developed a model for
monk’s food bowl production on occupational health safety and
environment at work for the encouragement of Rattanakosin local
wisdom at Banbart Community. The process of blowpipe welding
was necessary to produce the bowl which was very dangerous or
93.59% risk. After the employment of new sitting posture, the work
risk was lower 48.41% or moderate risk. When considering in details,
it was found that: 1) the traditional sitting posture could create work
risk at 88.89% while the new sitting posture could create the work
risk at 58.86%. 2) About the environmental pollution, with the
traditional sitting posture, workers exposed to the polluted fume from
welding at 61.11% while with the new sitting posture workers
exposed to the polluted fume from welding at 40.47%. 3) On
accidental risk, with the traditional sitting posture, workers exposed
to the accident from welding at 94.44% while with the new sitting
posture workers exposed to the accident from welding at 62.54%.
Abstract: In this study was performed in situ consolidation of polypropylene matrix/glass reinforced roving by combining heating systems and roll pressing. The commingled roving during hoop winding was winded on a cylindrical mandrel. The work also presents the advances made in the processing of these materials into composites by conventional technique filament winding. Experimental studies were performed with changing parameters – temperature, pressure and speed. Finally, it describes the investigation of the optimal processing conditions that maximize the mechanical properties of the composites. These properties are good enough for composites to be used as engineering materials in many structural applications.
Abstract: In this paper, five ontologies are described, which include the event concepts. The paper provides an overview and comparison of existing event models. The main criteria for comparison are that there should be possibilities to model events with stretch in the time and location and participation of objects; however, there are other factors that should be taken into account as well. The paper also shows an example of using ontologies in complex event processing.
Abstract: The unit root tests based on the robust estimator for the first-order autoregressive process are proposed and compared with the unit root tests based on the ordinary least squares (OLS) estimator. The percentiles of the null distributions of the unit root test are also reported. The empirical probabilities of Type I error and powers of the unit root tests are estimated via Monte Carlo simulation. Simulation results show that all unit root tests can control the probability of Type I error for all situations. The empirical power of the unit root tests based on the robust estimator are higher than the unit root tests based on the OLS estimator.
Abstract: The main purpose of this paper was to find a simple solution for load balancing and fault tolerance in OSGi. The challenge was to implement a highly available web application such as a shopping cart system with load balancing and fault tolerance, without having to change the core of OSGi.
Abstract: The aims of this research were to study the relationship between the Palaces (the Kings and the Royalty of the Chakri Dynasty) and the Buddhist temples including Wat Rajadhivas Vihara in Rattanakosin Period of Thailand with the purpose of creating knowledge for Thai lifelong learning, especially for Thai youth and children, and to create positive attitude on Nationalism, Buddhism and Monarchy of Thai people. The findings disclosed that the Palaces have had relationships with 33,902 temples, close relationship with 290 royal temples, and closer relationship with the 8 royal temples regarded as the “Temple of King Rama”. Moreover, there are only 16 Royal temples including Wat Rajadhivas Vihara where the Chakri Kings present the annual royal Kathin robes to the monks by themselves. Wat Rajadhivas Vihara has always been restored under royal patronage and served as royal shrine like the 8 Temples of King Rama.
Abstract: Evaluating the efficiency of decision making units has been frequently elaborated on in numerous publications. In this paper, the theoretical framework for a novel method of Distance Based Analysis (DBA) is presented. In addition, the method is performed on a sample of the ARWU’s top 54 Universities of the United States; the findings of which clearly demonstrate that the best ranked Universities are far from also being the most efficient.
Abstract: Currently, the sources of cultures and tourist attractions are presented in online documentary form only. In order to make them more virtual, the researcher then collected and presented them in the form of Virtual Temple. The prototype, which is a replica of the actual location, was developed to the website and allows people who are interested in Rattanakosin Island can see in form of Panorama Pan View. By this way, anyone can access the data and appreciate the beauty of Rattanakosin Island in the virtual model like the real place.
The result from the experiment showed that the levels of the knowledge on Thai temples in Rattanakosin Island increased; moreover, the users were highly satisfied with the systems. It can be concluded that virtual temples can support to publicize Thai arts, cultures and travels, as well as it can be utilized effectively.
Abstract: This study was conducted to determination of yield and yield components of some fodder beet types (Amarilla Barres, Feldherr, Kyros, Magnum ve Rota) under the Konya region conditions. Fodder beet was obtained from the Selcuk University, Faculty of Agriculture, at 2006-2007 season and the experiment was established in a randomized complete block design with three replicates. Differences among the averages of the fodder beet cultivars are statistically important in terms of all the characteristics investigated. Leaf attitude value was 1.2 – 2.2 (1=erect; 5= prostrate), root shape scale value was (1=spheroidal – 9=cylindrical), root diameter 11.0 – 12.2cm, remaining part of root on the ground was 6.3 – 13.7cm, root length was 21.4 – 29.6cm, leaf yield 1592 – 1917 kg/da, root yield was 10083 – 12258 kg/da, root dry matter content was %8.2 – 18.6 and root dry matter yield was 889 – 1887 kg/da. As a result of the study, it was determined that fodder beet cultivars are different conditions in terms of yield and yield components. Therefore, determination of appropriate cultivars for each region affect crop yield importantly.