Abstract: Biclustering is a very useful data mining technique for
identifying patterns where different genes are co-related based on a
subset of conditions in gene expression analysis. Association rules
mining is an efficient approach to achieve biclustering as in
BIMODULE algorithm but it is sensitive to the value given to its
input parameters and the discretization procedure used in the
preprocessing step, also when noise is present, classical association
rules miners discover multiple small fragments of the true bicluster,
but miss the true bicluster itself. This paper formally presents a
generalized noise tolerant bicluster model, termed as μBicluster. An
iterative algorithm termed as BIDENS based on the proposed model
is introduced that can discover a set of k possibly overlapping
biclusters simultaneously. Our model uses a more flexible method to
partition the dimensions to preserve meaningful and significant
biclusters. The proposed algorithm allows discovering biclusters that
hard to be discovered by BIMODULE. Experimental study on yeast,
human gene expression data and several artificial datasets shows that
our algorithm offers substantial improvements over several
previously proposed biclustering algorithms.