Abstract: Recurrent event data is a special type of multivariate
survival data. Dynamic and frailty models are one of the approaches
that dealt with this kind of data. A comparison between these two
models is studied using the empirical standard deviation of the
standardized martingale residual processes as a way of assessing the
fit of the two models based on the Aalen additive regression model.
Here we found both approaches took heterogeneity into account and
produce residual standard deviations close to each other both in the
simulation study and in the real data set.
Abstract: Heart failure is the most common reason of death
nowadays, but if the medical help is given directly, the patient-s life
may be saved in many cases. Numerous heart diseases can be
detected by means of analyzing electrocardiograms (ECG). Artificial
Neural Networks (ANN) are computer-based expert systems that
have proved to be useful in pattern recognition tasks. ANN can be
used in different phases of the decision-making process, from
classification to diagnostic procedures. This work concentrates on a
review followed by a novel method.
The purpose of the review is to assess the evidence of healthcare
benefits involving the application of artificial neural networks to the
clinical functions of diagnosis, prognosis and survival analysis, in
ECG signals. The developed method is based on a compound neural
network (CNN), to classify ECGs as normal or carrying an
AtrioVentricular heart Block (AVB). This method uses three
different feed forward multilayer neural networks. A single output
unit encodes the probability of AVB occurrences. A value between 0
and 0.1 is the desired output for a normal ECG; a value between 0.1
and 1 would infer an occurrence of an AVB. The results show that
this compound network has a good performance in detecting AVBs,
with a sensitivity of 90.7% and a specificity of 86.05%. The accuracy
value is 87.9%.
Abstract: This paper presents a new heuristic algorithm useful
for long-term planning of survivable WDM networks. A multi-period
model is formulated that combines network topology design and
capacity expansion. The ability to determine network expansion
schedules of this type becomes increasingly important to the
telecommunications industry and to its customers. The solution
technique consists of a Genetic Algorithm that allows generating
several network alternatives for each time period simultaneously and
shortest-path techniques to deduce from these alternatives a least-cost
network expansion plan over all time periods. The multi-period
planning approach is illustrated on a realistic network example.
Extensive simulations on a wide range of problem instances are
carried out to assess the cost savings that can be expected by
choosing a multi-period planning approach instead of an iterative
network expansion design method.
Abstract: Interest in Human Consciousness has been revived in the late 20th century from different scientific disciplines. Consciousness studies involve both its understanding and its application. In this paper, a computational model of the minimum consciousness functions necessary in my point of view for Artificial Intelligence applications is presented with the aim of improving the way computations will be made in the future. In section I, human consciousness is briefly described according to the scope of this paper. In section II, a minimum set of consciousness functions is defined - based on the literature reviewed - to be modelled, and then a computational model of these functions is presented in section III. In section IV, an analysis of the model is carried out to describe its functioning in detail.
Abstract: In this study, the powders of Ni and Ti with 50.5 at.%
Ni for 12 h were blended and cold pressed at the different pressures
(50, 75 and100 MPa).The porous product obtained after Ni-Ti
compacts were synthesized by SHS (self-propagating hightemperature
synthesis) in the different preheating temperatures (200,
250 and 300oC) and heating rates (30, 60 and 90oC/min). The effects
of the pressure, preheating temperature and heating rate were
investigated on biocompatibility in vivo. The porosity in the
synthesized products was in the range of 50.7–59.7 vol. %. The
pressure, preheating temperature and heating rate were found to have
an important effect on the biocompatibility in-vivo of the synthesized
products. Max. fibrotic tissue within the porous implant was found in
vivo periods (6 months), in which compacting pressure 100MPa.
Abstract: Over 90% of the world trade is carried by the
international shipping industry. As most of the countries are
developing, seaborne trade continues to expand to bring benefits for
consumers across the world. Studies show that world trade will
increase 70-80% through shipping in the next 15-20 years. Present
global fleet of 70000 commercial ships consumes approximately 200
million tonnes of diesel fuel a year and it is expected that it will be
around 350 million tonnes a year by 2020. It will increase the
demand for fuel and also increase the concentration of CO2 in the
atmosphere. So, it-s essential to control this massive fuel
consumption and CO2 emission. The idea is to utilize a diesel-wind
hybrid system for ship propulsion. Use of wind energy by installing
modern wing-sails in ships can drastically reduce the consumption of
diesel fuel. A huge amount of wind energy is available in oceans.
Whenever wind is available the wing-sails would be deployed and
the diesel engine would be throttled down and still the same forward
speed would be maintained. Wind direction in a particular shipping
route is not same throughout; it changes depending upon the global
wind pattern which depends on the latitude. So, the wing-sail
orientation should be such that it optimizes the use of wind energy.
We have made a computer programme in which by feeding the data
regarding wind velocity, wind direction, ship-motion direction; we
can find out the best wing-sail position and fuel saving for
commercial ships. We have calculated net fuel saving in certain
international shipping routes, for instance, from Mumbai in India to
Durban in South Africa. Our estimates show that about 8.3% diesel
fuel can be saved by utilizing the wind. We are also developing an
experimental model of the ship employing airfoils (small scale wingsail)
and going to test it in National Wind Tunnel Facility in IIT
Kanpur in order to develop a control mechanism for a system of
airfoils.
Abstract: A research program is conducted to evaluate the
mechanical properties of Ultra High Performance Concrete, target
compressive strength at the age of 28 days being more than 150 MPa.
The methodology to develop such mix has been explained. The
material properties, mix design and curing regime are determined.
The material attributes are understood by studying the stress strain
behaviour of UHPC cylinders under uniaxial compressive loading.
The load –crack mouth opening displacement (cmod) of UHPC
beams, flexural strength and fracture energy was evaluated using
third point loading test. Compressive strength and Split tensile
strength results are determined to find out the compressive and tensile
behaviour. Residual strength parameters are presented vividly
explaining the flexural performance, toughness of concrete.Durability
studies were also done to compare the effect of fibre to that of a
control mix For all the studies the Mechanical properties were
evaluated by varying the percentage and aspect ratio of steel fibres
The results reflected that higher aspect ratio and fibre volume
produced drastic changes in the cube strength, cylinder strength, post
peak response, load-cmod, fracture energy flexural strength, split
tensile strength, residual strength and durability. In regards to null
application of UHPC in India, an initiative is undertaken to
comprehend the mechanical behaviour of UHPC, which will be vital
for longer run in commercialization for structural applications.
Abstract: In the present work flow past circular cylinder and
cylinder with rectangular and triangular wake splitter is studied to
improve aerodynamic parameters. The Comparison of drag
coefficient is tabulated for bare cylinder, cylinder with rectangular
and triangular wake splitters. Flow past circular cylinder and cylinder
with triangular and rectangular wake splitter is performed at
Reynoldsnumber 5, 20, 40, 50,80, 100.An incompressible PISO finite
volume code employing a non-staggered grid arrangement is used, a
second order upwind scheme is used for convective terms. The time
discretization is implicit and a Second order Crank-Nicholson scheme
is employed. Length of wake splitter in both configurations is taken
to be equal to diameter of cylinder. Wake length is found to be less
with rectangular wake splitter when compared to bare cylinder and
cylinder with triangular wake splitter. Coefficient of drag is found to
be less for triangular wake splitter when compared to bare cylinder &
cylinder with rectangular wake splitter.
Abstract: Background: This investigated the mental health of the elderly survivors six months, ten months and two years after the “5.12 Wenchuan" earthquake. Methods: Two hundred and thirty-two physically healthy older survivors from earthquake-affected Mianyang County were interviewed. The measures included the Revised Impact of Event Scale (IES-R, Chinese version, for PTSD) and a Chinese Mental Health Inventory for the Elderly (MHIE). A repeated measures ANOVA test was used for statistical analysis. Results: The follow-up group had a statistically significant lower IES-R score and lower MHIE score than the initial group ten months after the earthquake. Two years later, the score of IES-R in follow-up group were still lower than that of non-follow-up group, but no differences were significant on the score of MHIE between groups. Furthermore, a negative relationship was found between scores of IES-R and MHIE. Conclusion: The earthquake has had a persistent negative impact on older survivors- mental health within the two-year period and that although the PTSD level declined significantly with time, it did not disappear completely.
Abstract: This research is a comparative study of complexity, as a multidimensional concept, in the context of streetscape composition in Algeria and Japan. 80 streetscapes visual arrays have been collected and then presented to 20 participants, with different cultural backgrounds, in order to be categorized and classified according to their degrees of complexity. Three analysis methods have been used in this research: cluster analysis, ranking method and Hayashi Quantification method (Method III). The results showed that complexity, disorder, irregularity and disorganization are often conflicting concepts in the urban context. Algerian daytime streetscapes seem to be balanced, ordered and regular, and Japanese daytime streetscapes seem to be unbalanced, regular and vivid. Variety, richness and irregularity with some aspects of order and organization seem to characterize Algerian night streetscapes. Japanese night streetscapes seem to be more related to balance, regularity, order and organization with some aspects of confusion and ambiguity. Complexity characterized mainly Algerian avenues with green infrastructure. Therefore, for Japanese participants, Japanese traditional night streetscapes were complex. And for foreigners, Algerian and Japanese avenues nightscapes were the most complex visual arrays.
Abstract: Intravitreal injection (IVI) is the most common treatment for eye posterior segment diseases such as endopthalmitis, retinitis, age-related macular degeneration, diabetic retinopathy, uveitis, and retinal detachment. Most of the drugs used to treat vitreoretinal diseases, have a narrow concentration range in which they are effective, and may be toxic at higher concentrations. Therefore, it is critical to know the drug distribution within the eye following intravitreal injection. Having knowledge of drug distribution, ophthalmologists can decide on drug injection frequency while minimizing damage to tissues. The goal of this study was to develop a computer model to predict intraocular concentrations and pharmacokinetics of intravitreally injected drugs. A finite volume model was created to predict distribution of two drugs with different physiochemical properties in the rabbit eye. The model parameters were obtained from literature review. To validate this numeric model, the in vivo data of spatial concentration profile from the lens to the retina were compared with the numeric data. The difference was less than 5% between the numerical and experimental data. This validation provides strong support for the numerical methodology and associated assumptions of the current study.
Abstract: Plasmodium vivax malaria differs from P. falciparum malaria in that a person suffering from P. vivax infection can suffer relapses of the disease. This is due the parasite being able to remain dormant in the liver of the patients where it is able to re-infect the patient after a passage of time. During this stage, the patient is classified as being in the dormant class. The model to describe the transmission of P. vivax malaria consists of a human population divided into four classes, the susceptible, the infected, the dormant and the recovered. The effect of a time delay on the transmission of this disease is studied. The time delay is the period in which the P. vivax parasite develops inside the mosquito (vector) before the vector becomes infectious (i.e., pass on the infection). We analyze our model by using standard dynamic modeling method. Two stable equilibrium states, a disease free state E0 and an endemic state E1, are found to be possible. It is found that the E0 state is stable when a newly defined basic reproduction number G is less than one. If G is greater than one the endemic state E1 is stable. The conditions for the endemic equilibrium state E1 to be a stable spiral node are established. For realistic values of the parameters in the model, it is found that solutions in phase space are trajectories spiraling into the endemic state. It is shown that the limit cycle and chaotic behaviors can only be achieved with unrealistic parameter values.
Abstract: The most Malaria cases are occur along Thai-Mynmar border. Mathematical model for the transmission of Plasmodium falciparum and Plasmodium vivax malaria in a mixed population of Thais and migrant Burmese living along the Thai-Myanmar Border is studied. The population is separated into two groups, Thai and Burmese. Each population is divided into susceptible, infected, dormant and recovered subclasses. The loss of immunity by individuals in the infected class causes them to move back into the susceptible class. The person who is infected with Plasmodium vivax and is a member of the dormant class can relapse back into the infected class. A standard dynamical method is used to analyze the behaviors of the model. Two stable equilibrium states, a disease-free state and an epidemic state, are found to be possible in each population. A disease-free equilibrium state in the Thai population occurs when there are no infected Burmese entering the community. When infected Burmese enter the Thai community, an epidemic state can occur. It is found that the disease-free state is stable when the threshold number is less than one. The epidemic state is stable when a second threshold number is greater than one. Numerical simulations are used to confirm the results of our model.