Abstract: Patients with diabetes are susceptible to chronic foot
wounds which may be difficult to manage and slow to heal.
Diagnosis and treatment currently rely on the subjective judgement of
experienced professionals. An objective method of tissue assessment
is required. In this paper, a data fusion approach was taken to wound
tissue classification. The supervised Maximum Likelihood and
unsupervised Multi-Modal Expectation Maximisation algorithms
were used to classify tissues within simulated wound models by
weighting the contributions of both colour and 3D depth information.
It was found that, at low weightings, depth information could show
significant improvements in classification accuracy when compared
to classification by colour alone, particularly when using the
maximum likelihood method. However, larger weightings were
found to have an entirely negative effect on accuracy.
Abstract: Speckled images arise when coherent microwave,
optical, and acoustic imaging techniques are used to image an object, surface or scene. Examples of coherent imaging systems include synthetic aperture radar, laser imaging systems, imaging sonar
systems, and medical ultrasound systems. Speckle noise is a form of object or target induced noise that results when the surface of the object is Rayleigh rough compared to the wavelength of the illuminating radiation. Detection and estimation in images corrupted
by speckle noise is complicated by the nature of the noise and is not
as straightforward as detection and estimation in additive noise. In
this work, we derive stochastic models for speckle noise, with an emphasis on speckle as it arises in medical ultrasound images. The
motivation for this work is the problem of segmentation and tissue classification using ultrasound imaging. Modeling of speckle in this
context involves partially developed speckle model where an underlying Poisson point process modulates a Gram-Charlier series
of Laguerre weighted exponential functions, resulting in a doubly
stochastic filtered Poisson point process. The statistical distribution of partially developed speckle is derived in a closed canonical form.
It is observed that as the mean number of scatterers in a resolution cell is increased, the probability density function approaches an
exponential distribution. This is consistent with fully developed speckle noise as demonstrated by the Central Limit theorem.
Abstract: The development of aid's systems for the medical
diagnosis is not easy thing because of presence of inhomogeneities in
the MRI, the variability of the data from a sequence to the other as
well as of other different source distortions that accentuate this
difficulty. A new automatic, contextual, adaptive and robust
segmentation procedure by MRI brain tissue classification is
described in this article. A first phase consists in estimating the
density of probability of the data by the Parzen-Rozenblatt method.
The classification procedure is completely automatic and doesn't
make any assumptions nor on the clusters number nor on the
prototypes of these clusters since these last are detected in an
automatic manner by an operator of mathematical morphology called
skeleton by influence zones detection (SKIZ). The problem of
initialization of the prototypes as well as their number is transformed
in an optimization problem; in more the procedure is adaptive since it
takes in consideration the contextual information presents in every
voxel by an adaptive and robust non parametric model by the
Markov fields (MF). The number of bad classifications is reduced by
the use of the criteria of MPM minimization (Maximum Posterior
Marginal).
Abstract: Fourier transform infrared (FT-IR) spectroscopic imaging
is an emerging technique that provides both chemically and
spatially resolved information. The rich chemical content of data
may be utilized for computer-aided determinations of structure and
pathologic state (cancer diagnosis) in histological tissue sections for
prostate cancer. FT-IR spectroscopic imaging of prostate tissue has
shown that tissue type (histological) classification can be performed to
a high degree of accuracy [1] and cancer diagnosis can be performed
with an accuracy of about 80% [2] on a microscopic (≈ 6μm)
length scale. In performing these analyses, it has been observed
that there is large variability (more than 60%) between spectra from
different points on tissue that is expected to consist of the same
essential chemical constituents. Spectra at the edges of tissues are
characteristically and consistently different from chemically similar
tissue in the middle of the same sample. Here, we explain these
differences using a rigorous electromagnetic model for light-sample
interaction. Spectra from FT-IR spectroscopic imaging of chemically
heterogeneous samples are different from bulk spectra of individual
chemical constituents of the sample. This is because spectra not
only depend on chemistry, but also on the shape of the sample.
Using coupled wave analysis, we characterize and quantify the nature
of spectral distortions at the edges of tissues. Furthermore, we
present a method of performing histological classification of tissue
samples. Since the mid-infrared spectrum is typically assumed to
be a quantitative measure of chemical composition, classification
results can vary widely due to spectral distortions. However, we
demonstrate that the selection of localized metrics based on chemical
information can make our data robust to the spectral distortions
caused by scattering at the tissue boundary.