Abstract: The healthcare environment is generally perceived as
being information rich yet knowledge poor. However, there is a lack
of effective analysis tools to discover hidden relationships and trends
in data. In fact, valuable knowledge can be discovered from
application of data mining techniques in healthcare system. In this
study, a proficient methodology for the extraction of significant
patterns from the Coronary Heart Disease warehouses for heart
attack prediction, which unfortunately continues to be a leading cause
of mortality in the whole world, has been presented. For this purpose,
we propose to enumerate dynamically the optimal subsets of the
reduced features of high interest by using rough sets technique
associated to dynamic programming. Therefore, we propose to
validate the classification using Random Forest (RF) decision tree to
identify the risky heart disease cases. This work is based on a large
amount of data collected from several clinical institutions based on
the medical profile of patient. Moreover, the experts- knowledge in
this field has been taken into consideration in order to define the
disease, its risk factors, and to establish significant knowledge
relationships among the medical factors. A computer-aided system is
developed for this purpose based on a population of 525 adults. The
performance of the proposed model is analyzed and evaluated based
on set of benchmark techniques applied in this classification problem.