Abstract: Medicinal plants are now gaining attractiveness in
treatment of bacterial infections and food preservation. The objective
of this study was to assess antibacterial activity of some medicinal
plants on pathogenic bacteria. Screening of antibacterial activity of
aqueous and methanol extracts of some plants: Jojoba, Ginger, Sage,
Thyme and Clove against Bacillus cereus, Salmonella typhimurium,
Staphylococcus aureus, Clostridium perfringens and Escherichia coli
were investigated. Antibacterial activity was performed by agar
diffusion and disc diffusion method. Jatropha, Jojoba, Clove and
Ginger extracts showed notable bacterial activity in the first
screening step then selected to be tested against Bacillus cereus
(Gram+), Staphylococcus aureus (Gram+) and Salmonella
typhimurium (Gram−) and their effect was compared using
antibiotics as control. Screening results showed potential antibacterial
activity of the tested plant extracts against the screened bacterial
strains. It was found that methanol extracts exhibited higher
antibacterial activity than aqueous extracts. Methanol extract of
Jatropha showed the highest inhibition zone against Staphylococcus
aureus (Gram+) with 24.00 mm diameter, compared to the other
plant extracts followed by clove. Meanwhile, the inhibition zones of
methanol extracts of Jojoba and Ginger were the same (12mm).The
Gram-positive bacteria were found to be more sensitive to aqueous
and methanol extracts than Gram-negative bacteria.
Abstract: In this investigation, the antibacterial effects of
ethanolic and 7:3 isopropyl –hexane mixture extracts of Zingiber
officinale were evaluated against three Gram positive bacteria, B.
cereus, S.epidermidis, S. aureus and three Gram negative bacteria, E.
coli, K.pneumonia and P.areuginosa. Utilizing paper disk diffusion
and well methods in-vitro, MIC and MBC were determined by
macrodilution. The results showed that ethanolic rhizome extract of
ginger had significantly active than Isopropyl –hexan extract. Further
work needs to be done in these extracts including fractionation to
isolate active constituents and subsequent pharmacological
evaluation.