Abstract: Biopharmaceuticals manufacturing is one of the major economic activities worldwide. Ninety-three percent of the workforce in a biomanufacturing environment concentrates in production-related areas. As a result, strategic collaborations between industry and academia are crucial to ensure the availability of knowledgeable workforce needed in an economic region to become competitive in biomanufacturing. In the past decade, our institution has been a key strategic partner with multinational biotechnology companies in supplying science and engineering graduates in the field of industrial biotechnology. Initiatives addressing all levels of the educational pipeline, from K-12 to college to continued education for company employees have been established along a ten-year span. The Amgen BioTalents Program was designed to provide undergraduate science and engineering students with training in biomanufacturing. The areas targeted by this educational program enhance their academic development, since these topics are not part of their traditional science and engineering curricula. The educational curriculum involved the process of producing a biomolecule from the genetic engineering of cells to the production of an especially targeted polypeptide, protein expression and purification, to quality control, and validation. This paper will report and describe the implementation details and outcomes of the first sessions of the program.
Abstract: Rapid prototyping (RP) techniques are a group of
advanced manufacturing processes that can produce custom made
objects directly from computer data such as Computer Aided Design
(CAD), Computed Tomography (CT) and Magnetic Resonance
Imaging (MRI) data. Using RP fabrication techniques, constructs
with controllable and complex internal architecture with appropriate
mechanical properties can be achieved. One of the attractive and
promising utilization of RP techniques is related to tissue engineering
(TE) scaffold fabrication. Tissue engineering scaffold is a 3D
construction that acts as a template for tissue regeneration. Although
several conventional techniques such as solvent casting and gas
forming are utilized in scaffold fabrication; these processes show
poor interconnectivity and uncontrollable porosity of the produced
scaffolds. So, RP techniques become the best alternative fabrication
methods of TE scaffolds. This paper reviews the current state of the
art in the area of tissue engineering scaffolds fabrication using
advanced RP processes, as well as the current limitations and future
trends in scaffold fabrication RP techniques.