Abstract: A new method for low complexity image coding is presented, that permits different settings and great scalability in the generation of the final bit stream. This coding presents a continuoustone still image compression system that groups loss and lossless compression making use of finite arithmetic reversible transforms. Both transformation in the space of color and wavelet transformation are reversible. The transformed coefficients are coded by means of a coding system in depending on a subdivision into smaller components (CFDS) similar to the bit importance codification. The subcomponents so obtained are reordered by means of a highly configure alignment system depending on the application that makes possible the re-configure of the elements of the image and obtaining different levels of importance from which the bit stream will be generated. The subcomponents of each level of importance are coded using a variable length entropy coding system (VBLm) that permits the generation of an embedded bit stream. This bit stream supposes itself a bit stream that codes a compressed still image. However, the use of a packing system on the bit stream after the VBLm allows the realization of a final highly scalable bit stream from a basic image level and one or several enhance levels.
Abstract: Background: Dialign is a DNA/Protein alignment tool
for performing pairwise and multiple pairwise alignments through the
comparison of gap-free segments (fragments) between sequence
pairs. An alignment of two sequences is a chain of fragments, i.e
local gap-free pairwise alignments, with the highest total score.
METHOD: A new approach is defined in this article which relies on
the concept of using three-dimensional fragments – i.e. local threeway
alignments -- in the alignment process instead of twodimensional
ones. These three-dimensional fragments are gap-free
alignments constituting of equal-length segments belonging to three
distinct sequences. RESULTS: The obtained results showed good
improvments over the performance of DIALIGN.
Abstract: The major objective of this paper is to introduce a new method to select genes from DNA microarray data. As criterion to select genes we suggest to measure the local changes in the correlation graph of each gene and to select those genes whose local changes are largest. More precisely, we calculate the correlation networks from DNA microarray data of cervical cancer whereas each network represents a tissue of a certain tumor stage and each node in the network represents a gene. From these networks we extract one tree for each gene by a local decomposition of the correlation network. The interpretation of a tree is that it represents the n-nearest neighbor genes on the n-th level of a tree, measured by the Dijkstra distance, and, hence, gives the local embedding of a gene within the correlation network. For the obtained trees we measure the pairwise similarity between trees rooted by the same gene from normal to cancerous tissues. This evaluates the modification of the tree topology due to tumor progression. Finally, we rank the obtained similarity values from all tissue comparisons and select the top ranked genes. For these genes the local neighborhood in the correlation networks changes most between normal and cancerous tissues. As a result we find that the top ranked genes are candidates suspected to be involved in tumor growth. This indicates that our method captures essential information from the underlying DNA microarray data of cervical cancer.
Abstract: Many IT projects come to failure because of having
technical approach, focusing on the final product and lack of proper
attention to strategic alignment. Project management models quite
often have technical management view [4], [8], [13], [14]. These
models focus greatly on the finalization of the project product and the
delivery of the product to the customer. However, many project
problems are due to lack of attention to the needs and capabilities of
the organizations or disregarding how to deploy and use the product
in the organization. In this regard, in the current research we are
trying to present a solution with the purpose of raising the value of
the project in an organization. This way, the project outputs will be
properly deployed in the organization. Therefore, a comprehensive
model is presented which takes into account the whole processes
from initial step of project definition to the deployment of the final
outputs in the organization and then the definition of all roles and
responsibilities to put the model into practice. Taking into account
the opinions of experts and project managers, to prove the
performance of the model, the project problems were recognized and
based on the model, categorized and analyzed. And at the end it is
made clear that ignoring the proper definition of the project and not
having a proper understanding of the expected value on the one hand
and not supervising the emerged value in the process of production
and installment are among the most important factors that bring a
project to failure.
Abstract: When the profile information of an existing road is
missing or not up-to-date and the parameters of the vertical
alignment are needed for engineering analysis, the engineer has to recreate
the geometric design features of the road alignment using
collected profile data. The profile data may be collected using
traditional surveying methods, global positioning systems, or digital
imagery. This paper develops a method that estimates the parameters
of the geometric features that best characterize the existing vertical
alignments in terms of tangents and the expressions of the curve, that
may be symmetrical, asymmetrical, reverse, and complex vertical
curves. The method is implemented using an Excel-based
optimization method that minimizes the differences between the
observed profile and the profiles estimated from the equations of the
vertical curve. The method uses a 'wireframe' representation of the
profile that makes the proposed method applicable to all types of
vertical curves. A secondary contribution of this paper is to introduce
the properties of the equal-arc asymmetrical curve that has been
recently developed in the highway geometric design field.
Abstract: Discharges in hydrogen, ignited by wire explosion, with current amplitude up to 1.5 MA were investigated. Channel diameter oscillations were observed on the photostreaks. Voltage and current curves correlated with the photostreaks. At initial gas pressure of 5-35 MPa the oscillation period was proportional to square root of atomic number of the initiating wire material. These oscillations were associated with aligned magnetic and gas-kinetic pressures. At initial pressure of 80-160 MPa acoustic pressure fluctuations on the discharge chamber wall were increased up to 150 MPa and there were the growth of voltage fluctuations on the discharge gap up to 3 kV simultaneously with it. In some experiments it was observed abrupt increase in the oscillation amplitude, which can be caused by the resonance of the acoustic oscillations in discharge chamber volume and the oscillations connected with alignment of the gaskinetic pressure and the magnetic pressure, as far as frequencies of these oscillations are close to each other in accordance with the estimates and the experimental data. Resonance of different type oscillations can produce energy density increasing in the discharge channel. Thus, the appropriate initial conditions in the experiment allow to increase the energy density in the discharge channel
Abstract: Spectrum is a scarce commodity, and considering the spectrum scarcity faced by the wireless-based service providers led to high congestion levels. Technical inefficiencies from pooled, since all networks share a common pool of channels, exhausting the available channels will force networks to block the services. Researchers found that cognitive radio (CR) technology may resolve the spectrum scarcity. A CR is a self-configuring entity in a wireless networking that senses its environment, tracks changes, and frequently exchanges information with their networks. However, CRN facing challenges and condition become worst while tracks changes i.e. reallocation of another under-utilized channels while primary network user arrives. In this paper, channels or resource reallocation technique based on DNA-inspired computing algorithm for CRN has been proposed.
Abstract: Design should be viewed concurrently by three ways
as transformation, flow and value generation. An innovative approach
to solve design – related problems is described as the integrated
product - process design. As a foundation for a formal framework
consisting of organizing principles and techniques, Work Structuring
has been developed to guide efforts in the integration that enhances
the development of operation and process design in alignment with
product design.
Vietnam construction projects are facing many delays, and cost
overruns caused mostly by design related problems. A better design
management that integrates product and process design could resolve
these problems. A questionnaire survey and in – depth interviews
were used to investigate the feasibility of applying Work Structuring
to construction projects in Vietnam.
The purpose of this paper is to present the research results and to
illustrate the possible problems and potential solutions when Work
Structuring is implemented to construction projects in Vietnam.
Abstract: Multiple sequence alignment is a fundamental part in
many bioinformatics applications such as phylogenetic analysis.
Many alignment methods have been proposed. Each method gives a
different result for the same data set, and consequently generates a
different phylogenetic tree. Hence, the chosen alignment method
affects the resulting tree. However in the literature, there is no
evaluation of multiple alignment methods based on the comparison of
their phylogenetic trees. This work evaluates the following eight
aligners: ClustalX, T-Coffee, SAGA, MUSCLE, MAFFT, DIALIGN,
ProbCons and Align-m, based on their phylogenetic trees (test trees)
produced on a given data set. The Neighbor-Joining method is used
to estimate trees. Three criteria, namely, the dNNI, the dRF and the
Id_Tree are established to test the ability of different alignment
methods to produce closer test tree compared to the reference one
(true tree). Results show that the method which produces the most
accurate alignment gives the nearest test tree to the reference tree.
MUSCLE outperforms all aligners with respect to the three criteria
and for all datasets, performing particularly better when sequence
identities are within 10-20%. It is followed by T-Coffee at lower
sequence identity (30%), trees scores of all methods
become similar.
Abstract: Flight management system (FMS) is a specialized
computer system that automates a wide variety of in-flight tasks,
reducing the workload on the flight crew to the point that modern
aircraft no longer carry flight engineers or navigators. The primary
function of FMS is to perform the in-flight management of the flight
plan using various sensors (such as GPS and INS often backed up by
radio navigation) to determine the aircraft's position. From the
cockpit FMS is normally controlled through a Control Display Unit
(CDU) which incorporates a small screen and keyboard or touch
screen. This paper investigates the performance of GPS/ INS
integration techniques in which the data fusion process is done using
Kalman filtering. This will include the importance of sensors
calibration as well as the alignment of the strap down inertial
navigation system. The limitations of the inertial navigation systems
are investigated in order to understand why INS sometimes is
integrated with other navigation aids and not just operating in standalone
mode. Finally, both the loosely coupled and tightly coupled
configurations are analyzed for several types of situations and
operational conditions.
Abstract: Protein 3D structure prediction has always been an
important research area in bioinformatics. In particular, the
prediction of secondary structure has been a well-studied research
topic. Despite the recent breakthrough of combining multiple
sequence alignment information and artificial intelligence algorithms
to predict protein secondary structure, the Q3 accuracy of various
computational prediction algorithms rarely has exceeded 75%. In a
previous paper [1], this research team presented a rule-based method
called RT-RICO (Relaxed Threshold Rule Induction from Coverings)
to predict protein secondary structure. The average Q3 accuracy on
the sample datasets using RT-RICO was 80.3%, an improvement
over comparable computational methods. Although this demonstrated
that RT-RICO might be a promising approach for predicting
secondary structure, the algorithm-s computational complexity and
program running time limited its use. Herein a parallelized
implementation of a slightly modified RT-RICO approach is
presented. This new version of the algorithm facilitated the testing of
a much larger dataset of 396 protein domains [2]. Parallelized RTRICO
achieved a Q3 score of 74.6%, which is higher than the
consensus prediction accuracy of 72.9% that was achieved for the
same test dataset by a combination of four secondary structure
prediction methods [2].
Abstract: The literature reports a large number of approaches for
measuring the similarity between protein sequences. Most of these
approaches estimate this similarity using alignment-based techniques
that do not necessarily yield biologically plausible results, for two
reasons.
First, for the case of non-alignable (i.e., not yet definitively aligned
and biologically approved) sequences such as multi-domain, circular
permutation and tandem repeat protein sequences, alignment-based
approaches do not succeed in producing biologically plausible results.
This is due to the nature of the alignment, which is based on the
matching of subsequences in equivalent positions, while non-alignable
proteins often have similar and conserved domains in non-equivalent
positions.
Second, the alignment-based approaches lead to similarity measures
that depend heavily on the parameters set by the user for the alignment
(e.g., gap penalties and substitution matrices). For easily alignable
protein sequences, it's possible to supply a suitable combination of
input parameters that allows such an approach to yield biologically
plausible results. However, for difficult-to-align protein sequences,
supplying different combinations of input parameters yields different
results. Such variable results create ambiguities and complicate the
similarity measurement task.
To overcome these drawbacks, this paper describes a novel and
effective approach for measuring the similarity between protein
sequences, called SAF for Substitution and Alignment Free. Without
resorting either to the alignment of protein sequences or to substitution
relations between amino acids, SAF is able to efficiently detect the
significant subsequences that best represent the intrinsic properties of
protein sequences, those underlying the chronological dependencies of
structural features and biochemical activities of protein sequences.
Moreover, by using a new efficient subsequence matching scheme,
SAF more efficiently handles protein sequences that contain similar
structural features with significant meaning in chronologically
non-equivalent positions. To show the effectiveness of SAF, extensive
experiments were performed on protein datasets from different
databases, and the results were compared with those obtained by
several mainstream algorithms.
Abstract: This study examines the possibility to apply the theory of multidimensional accounting (momentum accounting) in a Brazilian Navy-s Services Provider Military Organization (Organização Militar Prestadora de Serviços - OMPS). In general, the core of the said theory is the fact that Accounting does not recognize the inertia of transactions occurring in an entity, and that occur repeatedly in some cases, regardless of the implementation of new actions by its managers. The study evaluates the possibility of greater use of information recorded in the financial statements of the unit of analysis, within the strategic decisions of the organization. As a research strategy, we adopted the case study. The results infer that it is possible to use the theory in the context of a multidimensional OMPS, promoting useful information for decision-making and thereby contributing to the strengthening of the necessary alignment of its administration with the current desires of the Brazilian society.
Abstract: The purpose of this study is mainly to predict collision
frequency on the horizontal tangents combined with vertical curves
using artificial neural network methods. The proposed ANN models
are compared with existing regression models. First, the variables
that affect collision frequency were investigated. It was found that
only the annual average daily traffic, section length, access density,
the rate of vertical curvature, smaller curve radius before and after
the tangent were statistically significant according to related
combinations. Second, three statistical models (negative binomial,
zero inflated Poisson and zero inflated negative binomial) were
developed using the significant variables for three alignment
combinations. Third, ANN models are developed by applying the
same variables for each combination. The results clearly show that
the ANN models have the lowest mean square error value than those
of the statistical models. Similarly, the AIC values of the ANN
models are smaller to those of the regression models for all the
combinations. Consequently, the ANN models have better statistical
performances than statistical models for estimating collision
frequency. The ANN models presented in this paper are
recommended for evaluating the safety impacts 3D alignment
elements on horizontal tangents.
Abstract: Search for a tertiary substructure that geometrically
matches the 3D pattern of the binding site of a well-studied protein provides a solution to predict protein functions. In our previous work,
a web server has been built to predict protein-ligand binding sites
based on automatically extracted templates. However, a drawback of such templates is that the web server was prone to resulting in many
false positive matches. In this study, we present a sequence-order constraint to reduce the false positive matches of using automatically
extracted templates to predict protein-ligand binding sites. The binding site predictor comprises i) an automatically constructed template library and ii) a local structure alignment algorithm for
querying the library. The sequence-order constraint is employed to
identify the inconsistency between the local regions of the query protein and the templates. Experimental results reveal that the sequence-order constraint can largely reduce the false positive matches and is effective for template-based binding site prediction.
Abstract: F-actin fibrils are the cytoskeleton of osteocytes. They react in a dynamic manner to mechanical loading, and strength and
reposition their efforts to reinforce the cells structure. We hypothesize that f-actin is temporarly disrupted after loading and repolymerizes
in a new orientation to oppose the applied load. In vitro studies are conducted to determine f-actin disruption after varying mechanical stimulus parameters that are known to affect bone
formation. Results indicate that the f-actin cytoskeleton is disrupted in vitro as a function of applied mechanical stimulus parameters and
that the f-actin bundles reassemble after loading induced disruption
within 3 minutes after cessation of loading. The disruption of the factin
cytoskeleton depends on the magnitude of stretch, the numbers
of loading cycles, frequency, the insertion of rest between loading
cycles and extracellular calcium. In vivo studies also demonstrate
disruption of the f-actin cytoskeleton in cells embedded in the bone
matrix immediately after mechanical loading. These studies suggest
that adaptation of the f-actin fiber bundles of the cytoskeleton in
response to applied loads occurs by disruption and subsequent repolymerization.
Abstract: This study examines the structural and systematic processes of the Human Resources Division at The University of the West Indies, St. Augustine, Trinidad and Tobago for evidence of incorporation of the University's 2012- 2017 Strategic Plan. In conducting the study the structure of the Human Resources Management Division and its functions were carefully reviewed and measured against the strategic direction of the organisation. Findings indicate disconnect between these areas as there is apparent failure of the Human Resources Division to totally align its mandate with that of the organisation-s strategic direction. This action serves to threaten the viability of the organisation and its efficiency and effectiveness as an institution. The recommendations being put forward are for the realignment of the Human Resources Management Division and for its focus to mirror that of the organisation and the organisation-s goals and objectives. This may entail a restructuring of the Division.
Abstract: Color printing proceeds with multiple halftone
separations overlay. Because of separation overlay misalignment in
printing, the percentage of different primary color combination may
vary and it will result in color shift. In traditional printing procedure
with AM halftone, every separation has different screening angle to
make the superposition pattern in a random style, which will reduce
the color shift. To evaluate the color shift of printing with hybrid
halftoning, we simulate printing procedure with halftone images
overlay and calculate the color difference between expected color and
color in different overlay misalignment configurations. The color
difference for hybrid halftone and AM halftone is very close. So the
color shift for hybrid halftone is acceptable with current color printing
procedure.
Abstract: Bioinformatics and computational biology involve
the use of techniques including applied mathematics,
informatics, statistics, computer science, artificial intelligence,
chemistry, and biochemistry to solve biological problems
usually on the molecular level. Research in computational
biology often overlaps with systems biology. Major research
efforts in the field include sequence alignment, gene finding,
genome assembly, protein structure alignment, protein structure
prediction, prediction of gene expression and proteinprotein
interactions, and the modeling of evolution. Various
global rearrangements of permutations, such as reversals and
transpositions,have recently become of interest because of their
applications in computational molecular biology. A reversal is
an operation that reverses the order of a substring of a permutation.
A transposition is an operation that swaps two adjacent
substrings of a permutation. The problem of determining the
smallest number of reversals required to transform a given
permutation into the identity permutation is called sorting by
reversals. Similar problems can be defined for transpositions
and other global rearrangements. In this work we perform a
study about some genome rearrangement primitives. We show
how a genome is modelled by a permutation, introduce some
of the existing primitives and the lower and upper bounds
on them. We then provide a comparison of the introduced
primitives.
Abstract: Electro-optical devices are increasingly used for
military sea-, land- and air applications to detect, recognize and track
objects. Typically, these devices produce video information that is
presented to an operator. However, with increasing availability of
electro-optical devices the data volume is becoming very large,
creating a rising need for automated analysis. In a military setting,
this typically involves detecting and recognizing objects at a large
distance, i.e. when they are difficult to distinguish from background
and noise. One may consider combining multiple images from a
video stream into a single enhanced image that provides more
information for the operator. In this paper we investigate a simple
algorithm to enhance simulated images from a military context and
investigate how the enhancement is affected by various types of
disturbance.