Abstract: Annotation of a protein sequence is pivotal for the understanding of its function. Accuracy of manual annotation provided by curators is still questionable by having lesser evidence strength and yet a hard task and time consuming. A number of computational methods including tools have been developed to tackle this challenging task. However, they require high-cost hardware, are difficult to be setup by the bioscientists, or depend on time intensive and blind sequence similarity search like Basic Local Alignment Search Tool. This paper introduces a new method of assigning highly correlated Gene Ontology terms of annotated protein sequences to partially annotated or newly discovered protein sequences. This method is fully based on Gene Ontology data and annotations. Two problems had been identified to achieve this method. The first problem relates to splitting the single monolithic Gene Ontology RDF/XML file into a set of smaller files that can be easy to assess and process. Thus, these files can be enriched with protein sequences and Inferred from Electronic Annotation evidence associations. The second problem involves searching for a set of semantically similar Gene Ontology terms to a given query. The details of macro and micro problems involved and their solutions including objective of this study are described. This paper also describes the protein sequence annotation and the Gene Ontology. The methodology of this study and Gene Ontology based protein sequence annotation tool namely extended UTMGO is presented. Furthermore, its basic version which is a Gene Ontology browser that is based on semantic similarity search is also introduced.
Abstract: Walking as a type of non-motorized transportation has
various social, economical and environmental privileges. Also, today
different aspects of sustainable development have been emphasized
and promotion of sustainable transportation modes has been
considered according to this approach. Therefore, the objective of
this research is exploring the circumstance of relationship between
walking and sustainable urban transportation.For writing this article,
the most important resources related to the traits of walking have
been surveyed via a documentary method and after explaining the
concept of sustainable transportation and its indicators, benefiting
from the viewpoints of transportation experts of Tehran, as the capital
and greatest city of Iran, different modes of urban transportation have
been compared in proportion to each criterion and to each other and
have been analyzed according to AHP method. The results of this
study indicate that walking is the most sustainable mode of inner city
transportation.
Abstract: In this paper, a fractional-order FIR differentiator
design method using the differential evolution (DE) algorithm is
presented. In the proposed method, the FIR digital filter is designed to
meet the frequency response of a desired fractal-order differentiator,
which is evaluated in the frequency domain. To verify the design
performance, another design method considered in the time-domain is
also provided. Simulation results reveal the efficiency of the proposed
method.
Abstract: In order to compare the performance of the carbon dioxide and HFC-125 heat pumps for medium-and high-temperature heating, both heat pump cycles were optimized using a simulation method. To fairly compare the performance of the cycles by using different working fluids, each cycle was optimized from the viewpoint of heating COP by two design parameters. The first is the gas cooler exit temperature and the other is the ratio of the overall heat conductance of the gas cooler to the combined overall heat conductance of the gas cooler and the evaporator. The inlet and outlet temperatures of secondary fluid of the gas cooler were fixed at 40/90°C and 40/150°C.The results shows that the HFC-125 heat pump has 6% higher heating COP than carbon dioxide heat pump when the heat sink exit temperature is fixed at 90ºC, while the latter outperforms the former when the heat sink exit temperature is fixed at 150ºC under the simulation conditions considered in the present study.
Abstract: This paper presents an adaptive feedback linearization approach to derive helicopter. Ideal feedback linearization is defined for the cases when the system model is known. Adaptive feedback linearization is employed to get asymptotically exact cancellation for the inherent uncertainty in the knowledge of the given parameters of system. The control algorithm is implemented using the feedback linearization technique and adaptive method. The controller parameters are unknown where an adaptive control law aims to drive them towards their ideal values for providing perfect model matching between the reference model and the closed-loop plant model. The converged parameters of controller would then provide good estimates for the unknown plant parameters.
Abstract: Bond Graph as a unified multidisciplinary tool is widely
used not only for dynamic modelling but also for Fault Detection and
Isolation because of its structural and causal proprieties. A binary
Fault Signature Matrix is systematically generated but to make the
final binary decision is not always feasible because of the problems
revealed by such method. The purpose of this paper is introducing a
methodology for the improvement of the classical binary method of
decision-making, so that the unknown and identical failure signatures
can be treated to improve the robustness. This approach consists of
associating the evaluated residuals and the components reliability data
to build a Hybrid Bayesian Network. This network is used in two
distinct inference procedures: one for the continuous part and the
other for the discrete part. The continuous nodes of the network are
the prior probabilities of the components failures, which are used by
the inference procedure on the discrete part to compute the posterior
probabilities of the failures. The developed methodology is applied
to a real steam generator pilot process.
Abstract: The purpose of this study is to research on thoughts transmitted from virtual fitting-room and to deduce discussion in an auxiliary narrative way. The research structure is based on 3D virtual fitting-room as the research subject. Initially, we will discuss the principles of narrate study, User Demand and so on by using a narrative design pattern to transmit their objective indications of “people-situation-reason-object", etc, and then to analyze the virtual fitting-room examples that are able to provide a new thinking for designers who engaged in clothing related industry – which comes in “story telling" and “user-centered design" forms. Clothing designs are not just to cover up the body to keep warm but to draw closer to people-s demand physiologically and psychologically through interactive designs so as to achieve cognition between people and environment. In the “outside" goal of clothing-s functional designs, we use tribal group-s behavior characteristics to “transform" the existing personal cultural stories, and “reform" them to design appropriate interactive products. Synthesizing the above matters, apart from being able to regard “narrate" as a kind of functional thinking process, we are also able to regard it as a kind of choice, arrangement and an activity of story expression, allowing interactive design-s spirit, product characteristics and experience ideas be transmitted to target tribal group in a visual image performance method. It is a far more confident and innovative attempt, and meanwhile, able to achieve entertainment, joyful and so forth fundamental interactive transmissions. Therefore, this study takes “user-centered design" thinking as a basis to establish a set of clothing designs with interactive experience patterns and to assist designers to examine the five sensual feeling of interactive demands in order to initiate a new value in textile industry.
Abstract: The aim of this study was to extract sugar from
sugarcane using high electric field pulse (HELP) as a non-thermal cell permeabilization method. The result of this study showed that it
is possible to permeablize sugar cane cells using HELP at very short times (less than 10 sec.) and at room temperature. Increasing the field strength (from 0.5kV/cm to 2kV/cm) and pulse number (1 to 12) led to increasing the permeabilization of sugar cane cells. The energy
consumption during HELP treatment of sugar cane (2.4 kJ/kg) was about 100 times less compared to thermal cell disintegration at 85
Abstract: The electrokinetic flow resistance (electroviscous
effect) is predicted for steady state, pressure-driven liquid flow at
low Reynolds number in a microfluidic contraction of rectangular
cross-section. Calculations of the three dimensional flow are
performed in parallel using a finite volume numerical method. The
channel walls are assumed to carry a uniform charge density and the
liquid is taken to be a symmetric 1:1 electrolyte. Predictions are
presented for a single set of flow and electrokinetic parameters. It is
shown that the magnitude of the streaming potential gradient and the
charge density of counter-ions in the liquid is greater than that in
corresponding two-dimensional slit-like contraction geometry. The
apparent viscosity is found to be very close to the value for a
rectangular channel of uniform cross-section at the chosen Reynolds
number (Re = 0.1). It is speculated that the apparent viscosity for the
contraction geometry will increase as the Reynolds number is
reduced.
Abstract: A new hybrid coding method for compressing
animated polygonal meshes is presented. This paper assumes
the simplistic representation of the geometric data: a temporal
sequence of polygonal meshes for each discrete frame of the
animated sequence. The method utilizes a delta coding and an
octree-based method. In this hybrid method, both the octree
approach and the delta coding approach are applied to each
single frame in the animation sequence in parallel. The
approach that generates the smaller encoded file size is chosen
to encode the current frame. Given the same quality
requirement, the hybrid coding method can achieve much
higher compression ratio than the octree-only method or the
delta-only method. The hybrid approach can represent 3D
animated sequences with higher compression factors while
maintaining reasonable quality. It is easy to implement and have
a low cost encoding process and a fast decoding process, which
make it a better choice for real time application.
Abstract: Aim of this work was to compare the efficacy of two
loading methods of proteins onto polymeric nanocarriers: adsorption
and encapsulation methods. Preliminary studies of protein loading
were done using Bovine Serum Albumin (BSA) as model protein.
Nanocarriers were prepared starting from polylactic co-glycolic acid
(PLGA) polymer; production methods used are two different variants
of emulsion evaporation method. Nanoparticles obtained were
analyzed in terms of dimensions by Dynamic Light Scattering and
Loading Efficiency of BSA by Bradford Assay. Loaded
nanoparticles were then submitted to in-vitro protein dissolution test
in order to study the effect of the delivery system on the release rate
of the protein.
Abstract: In this study, the density dependent nonlinear reactiondiffusion
equation, which arises in the insect dispersal models, is
solved using the combined application of differential quadrature
method(DQM) and implicit Euler method. The polynomial based
DQM is used to discretize the spatial derivatives of the problem. The
resulting time-dependent nonlinear system of ordinary differential
equations(ODE-s) is solved by using implicit Euler method. The
computations are carried out for a Cauchy problem defined by a onedimensional
density dependent nonlinear reaction-diffusion equation
which has an exact solution. The DQM solution is found to be in a
very good agreement with the exact solution in terms of maximum
absolute error. The DQM solution exhibits superior accuracy at large
time levels tending to steady-state. Furthermore, using an implicit
method in the solution procedure leads to stable solutions and larger
time steps could be used.
Abstract: The effect of phosphorus supplementation of ammoniated rice straw was studied. The in vitro experiment was carried out following the first stage of Tilley and Terry method. The treatments consisting of four diets were A = 50% ammoniated rice straw + 50% concentrate (control), B = A + 0.2% Phosphor (P) supplement, C = A + 0.4% Phosphor (P) supplement, and D = A + 0.6% Phosphor (P) supplement of dry matter. Completely randomized design was used as the experimental design with differences among treatment means were examined using Duncan multiple range test. Variables measured were total bacterial and cellulolytic bacterial population, cellulolytic enzyme activity, ammonia (NH3) and volatile fatty acid (VFA) concentrations, as fermentability indicators and synthesized microbial protein, as well as degradability indicators including dry matter (DM), organic matter (OM), neutral detergent fibre (NDF), acid detergent fibre (ADF) and cellulose. The results indicated that fermentability and degradability of diets consisting ammoniated rice straw with P supplementation were significantly higher than the control diet (P< 0.05). It is concluded that P supplementation is important to improve fermentability and degradability of rations containing ammoniated RS and concentrate. In terms of the most effective level of P supplementation occurred at a supplementation rate of 0.4% of dry matter.
Abstract: Case-Based Reasoning (CBR) is one of machine
learning algorithms for problem solving and learning that caught a lot
of attention over the last few years. In general, CBR is composed of
four main phases: retrieve the most similar case or cases, reuse the
case to solve the problem, revise or adapt the proposed solution, and
retain the learned cases before returning them to the case base for
learning purpose. Unfortunately, in many cases, this retain process
causes the uncontrolled case base growth. The problem affects
competence and performance of CBR systems. This paper proposes
competence-based maintenance method based on deletion policy
strategy for CBR. There are three main steps in this method. Step 1,
formulate problems. Step 2, determine coverage and reachability set
based on coverage value. Step 3, reduce case base size. The results
obtained show that this proposed method performs better than the
existing methods currently discussed in literature.
Abstract: The RK1GL2X3 method is a numerical method for solving initial value problems in ordinary differential equations, and is based on the RK1GL2 method which, in turn, is a particular case of the general RKrGLm method. The RK1GL2X3 method is a fourth-order method, even though its underlying Runge-Kutta method RK1 is the first-order Euler method, and hence, RK1GL2X3 is considerably more efficient than RK1. This enhancement is achieved through an implementation involving triple-nested two-point Gauss- Legendre quadrature.
Abstract: In this paper two models using a functional network
were employed to solving classification problem. Functional networks
are generalized neural networks, which permit the specification of
their initial topology using knowledge about the problem at hand. In
this case, and after analyzing the available data and their relations, we
systematically discuss a numerical analysis method used for
functional network, and apply two functional network models to
solving XOR problem. The XOR problem that cannot be solved with
two-layered neural network can be solved by two-layered functional
network, which reveals a potent computational power of functional
networks, and the performance of the proposed model was validated
using classification problems.
Abstract: To increase precision and reliability of automatic control systems, we have to take into account of random factors affecting the control system. Thus, operational matrix technique is used for statistical analysis of first order plus time delay system with uniform random parameter. Examples with deterministic and stochastic disturbance are considered to demonstrate the validity of the method. Comparison with Monte Carlo method is made to show the computational effectiveness of the method.
Abstract: In this paper, a frequency-variation based method has
been proposed for transistor parameter estimation in a commonemitter
transistor amplifier circuit. We design an algorithm to estimate
the transistor parameters, based on noisy measurements of the output
voltage when the input voltage is a sine wave of variable frequency
and constant amplitude. The common emitter amplifier circuit has
been modelled using the transistor Ebers-Moll equations and the
perturbation technique has been used for separating the linear and
nonlinear parts of the Ebers-Moll equations. This model of the amplifier
has been used to determine the amplitude of the output sinusoid as
a function of the frequency and the parameter vector. Then, applying
the proposed method to the frequency components, the transistor
parameters have been estimated. As compared to the conventional
time-domain least squares method, the proposed method requires
much less data storage and it results in more accurate parameter
estimation, as it exploits the information in the time and frequency
domain, simultaneously. The proposed method can be utilized for
parameter estimation of an analog device in its operating range of
frequencies, as it uses data collected from different frequencies output
signals for parameter estimation.
Abstract: The overlay approach has been widely used by many service providers for Traffic Engineering (TE) in large Internet backbones. In the overlay approach, logical connections are set up between edge nodes to form a full mesh virtual network on top of the physical topology. IP routing is then run over the virtual network. Traffic engineering objectives are achieved through carefully routing logical connections over the physical links. Although the overlay approach has been implemented in many operational networks, it has a number of well-known scaling issues. This paper proposes a new approach to achieve traffic engineering without full-mesh overlaying with the help of integrated approach and equal subset split method. Traffic engineering needs to determine the optimal routing of traffic over the existing network infrastructure by efficiently allocating resource in order to optimize traffic performance on an IP network. Even though constraint-based routing [1] of Multi-Protocol Label Switching (MPLS) is developed to address this need, since it is not widely tested or debugged, Internet Service Providers (ISPs) resort to TE methods under Open Shortest Path First (OSPF), which is the most commonly used intra-domain routing protocol. Determining OSPF link weights for optimal network performance is an NP-hard problem. As it is not possible to solve this problem, we present a subset split method to improve the efficiency and performance by minimizing the maximum link utilization in the network via a small number of link weight modifications. The results of this method are compared against results of MPLS architecture [9] and other heuristic methods.
Abstract: In this paper, we proposed the direct method for converting
Finite-Impulse Response (FIR) filter with low nonzero tap
into Infinite-Impulse Response (IIR) filter using the pre-determined
table. The prony method is used by ghost cancellator which is IIR
approximation to FIR filter which is better performance than IIR and
have much larger calculation difference. The direct method for many
ghost combination with low nonzero tap of NTSC(National Television
System Committee) TV signal in Korea is described. The proposed
method is illustrated with an example.