Abstract: Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more exhaustive approach to test and screen out biomaterials. This paper develops the model of scaffolds and Computational Fluid Dynamics that show the value of computer simulations in determining the influence of the geometrical scaffold parameter porosity, pore size and shape on the permeability of scaffolds, magnitude of velocity, drop pressure, shear stress distribution and level and the proper design of the geometry of the scaffold. This creates a need for more advanced studies that include aspects of dynamic conditions of a micro fluid passing through the scaffold were characterized for tissue engineering applications and differentiation of tissues within scaffolds.
Abstract: Zero inflated Strict Arcsine model is a newly developed model which is found to be appropriate in modeling overdispersed count data. In this study, maximum likelihood estimation method is used in estimating the parameters for zero inflated strict arcsine model. Bootstrapping is then employed to compute the confidence intervals for the estimated parameters.
Abstract: Quantitative researching on the degree of incidence between the logistics industry and relevant macroscopic system elements is the basis of reasonable and scientific policy on industrial development. In the light of the macro-level, the logistics industry system is consisted of multiple macroscopic agents such as macro-economic, infrastructure, social environment, market demanding, the traditional industry, industry life cycle, policy , system and so on. This paper studies the grey incidence among the macroscopic agents in the logistics industry system. It is demonstrated that the releasing of the logistics services from the logistics outsourcing enterprises determines the growth of the logistics size. Although the information and communication technology is able to promote the formation of the modern logistics industry to some extent, the development of the modern logistics industry depends more on the development of national economy and the investment in the capital assets of the logistics industry.
Abstract: Vinegar is a precious food additive and complement as well as effective preservative against food spoilage. Recently traditional vinegar production has been improved using various natural substrates and fruits such as grape, palm, cherry, coconut, date, sugarcane, rice and balsam. These neoclassical fermentations resulted in several vinegar types with different tastes, fragrances and nutritional values because of applying various acetic acid bacteria as starters. Acetic acid bacteria include genera Acetobacter, Gluconacetobacter and Gluconobacter according to latest edition of Bergy-s Manual of Systematic Bacteriology that classifies genera on the basis of their 16s RNA differences. Acetobacter spp as the main vinegar starters belong to family Acetobacteraceae that are gram negative obligate aerobes, chemoorganotrophic bacilli that are oxidase negative and oxidize ethanol to acetic acid. In this research we isolated and identified a native Acetobacter strain with high acetic acid productivity and tolerance against high ethanol concentrations from Iranian peach as a summer delicious fruit that is very susceptible to food spoilage and decay. We used selective and specific laboratorial culture media such as Standard GYC, Frateur and Carr medium. Also we used a new industrial culture medium and a miniature fermentor with a new aeration system innovated by Pars Yeema Biotechnologists Co., Isfahan Science and Technology Town (ISTT), Isfahan, Iran. The isolated strain was successfully cultivated in modified Carr media with 2.5% and 5% ethanol simultaneously in high temperatures, 34 - 40º C after 96 hours of incubation period. We showed that the increase of ethanol concentration resulted in rising of strain sensitivity to high temperature. In conclusion we isolated and characterized a new Acetobacter strain from Iranian peach that could be considered as a potential strain for production of a new vinegar type, peach vinegar, with a delicious taste and advantageous nutritional value in food biotechnology and industrial microbiology.
Abstract: In order to develop any strategy, it is essential to first
identify opportunities, threats, weak and strong points. Assessment of
technology level provides the possibility of concentrating on weak
and strong points. The results of technology assessment have a direct
effect on decision making process in the field of technology transfer
or expansion of internal research capabilities so it has a critical role
in technology management. This paper presents a conceptual model
to analyze the technology capability of a company as a whole and in
four main aspects of technology. This model was tested on 10
automotive parts manufacturers in IRAN. Using this model,
capability level of manufacturers was investigated in four fields of
managing aspects, hard aspects, human aspects, and information and
knowledge aspects. Results show that these firms concentrate on hard
aspect of technology while others aspects are poor and need to be
supported more. So this industry should develop other aspects of
technology as well as hard aspect to have effective and efficient use
of its technology. These paper findings are useful for the technology
planning and management in automotive part manufactures in IRAN
and other Industries which are technology followers and transport
their needed technologies.
Abstract: High redundancy and strong uncertainty are two main characteristics for underwater robotic manipulators with unlimited workspace and mobility, but they also make the motion planning and control difficult and complex. In order to setup the groundwork for the research on control schemes, the mathematical representation is built by using the Denavit-Hartenberg (D-H) method [9]&[12]; in addition to the geometry of the manipulator which was studied for establishing the direct and inverse kinematics. Then, the dynamic model is developed and used by employing the Lagrange theorem. Furthermore, derivation and computer simulation is accomplished using the MATLAB environment. The result obtained is compared with mechanical system dynamics analysis software, ADAMS. In addition, the creation of intelligent artificial skin using Interlink Force Sensing ResistorTM technology is presented as groundwork for future work
Abstract: In this note, a theoretical model for analyzing of
normal penetration of the ogive – nose projectile into metallic targets
is presented .The failure is assumed to be asymmetry petalling and
the analysis is performed by using the energy balance and work done
.The work done consist of the work required for plastic deformation
Wp, the work for transferring the matter to new position Wd and the
work for bending of the petals Wb. In several studies, it has been
shown that we can neglect the loss of energy by temperature.
In this present study, in first, by assuming the crater formation
after perforation, the value of work done is calculated during the
normal penetration of conical projectiles into thin metallic targets.
Then the value of residual velocity and ballistic limit of the projectile
is predicated by using the energy balance. In final, theoretical and
experimental results is compared.
Abstract: Thepurpose of the research is to characterize the levels
of satisfaction of the students in e-learning post-graduate courses,
taking into account specific dimensions of the course which were
considered as benchmarks for the quality of this type of online
learning initiative, as well as the levels of satisfaction towards each
specific indicator identified in each dimension. It was also an aim of
this study to understand how thesedimensions relate to one another.
Using a quantitative research approach in the collection and analysis
of the data, the study involves the participation of the students who
attended on e-learning course in 2010/2011. The conclusions of this
study suggest that online students present relatively high levels of
satisfaction, which points towards a positive experience during the
course. It is possible to note that there is a correlation between the
different dimensions studied, consequently leading to different
improvement strategies. Ultimately, this investigation aims to
contribute to the promotion of quality and the success of e-learning
initiatives in Higher Education.
Abstract: This paper describes WiPoD (Wireless Position
Detector) which is a pure software based location determination and
tracking (positioning) system. It uses empirical signal strength measurements from different wireless access points for mobile user
positioning. It is designed to determine the location of users having
802.11 enabled mobile devices in an 802.11 WLAN infrastructure
and track them in real time. WiPoD is the first main module in our
LBS (Location Based Services) framework. We tested K-Nearest
Neighbor and Triangulation algorithms to estimate the position of a
mobile user. We also give the analysis results of these algorithms for
real time operations. In this paper, we propose a supportable, i.e.
understandable, maintainable, scalable and portable wireless
positioning system architecture for an LBS framework. The WiPoD
software has a multithreaded structure and was designed and implemented with paying attention to supportability features and real-time constraints and using object oriented design principles. We also describe the real-time software design issues of a wireless positioning system which will be part of an LBS framework.
Abstract: In this paper, a comparative study of application of
supervised and unsupervised learning algorithms on illumination
invariant face recognition has been carried out. The supervised
learning has been carried out with the help of using a bi-layered
artificial neural network having one input, two hidden and one output
layer. The gradient descent with momentum and adaptive learning
rate back propagation learning algorithm has been used to implement
the supervised learning in a way that both the inputs and
corresponding outputs are provided at the time of training the
network, thus here is an inherent clustering and optimized learning of
weights which provide us with efficient results.. The unsupervised
learning has been implemented with the help of a modified
Counterpropagation network. The Counterpropagation network
involves the process of clustering followed by application of Outstar
rule to obtain the recognized face. The face recognition system has
been developed for recognizing faces which have varying
illumination intensities, where the database images vary in lighting
with respect to angle of illumination with horizontal and vertical
planes. The supervised and unsupervised learning algorithms have
been implemented and have been tested exhaustively, with and
without application of histogram equalization to get efficient results.
Abstract: Complex assemblies of interacting proteins carry out
most of the interesting jobs in a cell, such as metabolism, DNA
synthesis, mitosis and cell division. These physiological properties
play out as a subtle molecular dance, choreographed by underlying
regulatory networks that control the activities of cyclin-dependent
kinases (CDK). The network can be modeled by a set of nonlinear
differential equations and its behavior predicted by numerical
simulation. In this paper, an innovative approach has been proposed
that uses genetic algorithms to mine a set of behavior data output by
a biological system in order to determine the kinetic parameters of
the system. In our approach, the machine learning method is
integrated with the framework of existent biological information in a
wiring diagram so that its findings are expressed in a form of system
dynamic behavior. By numerical simulations it has been illustrated
that the model is consistent with experiments and successfully shown
that such application of genetic algorithms will highly improve the
performance of mathematical model of the cell division cycle to
simulate such a complicated bio-system.
Abstract: The issue of real-time and reliable report delivery is extremely important for taking effective decision in a real world mission critical Wireless Sensor Network (WSN) based application. The sensor data behaves differently in many ways from the data in traditional databases. WSNs need a mechanism to register, process queries, and disseminate data. In this paper we propose an architectural framework for data placement and management. We propose a reliable and real time approach for data placement and achieving data integrity using self organized sensor clusters. Instead of storing information in individual cluster heads as suggested in some protocols, in our architecture we suggest storing of information of all clusters within a cell in the corresponding base station. For data dissemination and action in the wireless sensor network we propose to use Action and Relay Stations (ARS). To reduce average energy dissipation of sensor nodes, the data is sent to the nearest ARS rather than base station. We have designed our architecture in such a way so as to achieve greater energy savings, enhanced availability and reliability.
Abstract: The mechanical deformation and the electrical conductivity of lanthanum strontium cobalt ferrite oxide under uniaxial compression were investigated at various temperatures up to 1073 K. The material reveals a rather complex mechanical behaviour related to its ferroelasticity and completely different stress-strain curves are obtained during the 1st and 2nd loading cycles. A distinctive ferroelastic creep was observed at 293 K whilst typical ferroelastic stress-strain curve were obtained in the temperature range from 473 K to 873 K. At 1073 K, on the other hand, high-temperature creep deformation was observed instead of ferroelastic deformation. The conductivity increases with increasing compressive stress at all the temperatures. The increase in conductivity is related to both geometrical and piezoelectric effects. From 293 K to 873 K, where the material exhibits ferroelastic behaviour, the variation in the total conductivity decreases with increasing temperature. The contribution of the piezoelectric effect to the total conductivity variation also decreases with increasing temperature and the maximum in piezoconductivity has a value of about 0.75 % at 293 K for a compressive stress of 100 MPa. There is no effect of domain switching on conductivity except for the geometric effect. At 1073 K, the conductivity is simply proportional to the compressive strain.
Abstract: A new numerical method for simultaneously updating mass and stiffness matrices based on incomplete modal measured data is presented. By using the Kronecker product, all the variables that are to be modified can be found out and then can be updated directly. The optimal approximation mass matrix and stiffness matrix which satisfy the required eigenvalue equation and orthogonality condition are found under the Frobenius norm sense. The physical configuration of the analytical model is preserved and the updated model will exactly reproduce the modal measured data. The numerical example seems to indicate that the method is quite accurate and efficient.
Abstract: Protective effect of ethanolic extract of polyherbal formulation (PHF) was studied on carbon tetrachloride induced liver damage on carbon tetrachloride induced liver damage. Treatment of rats with 250mg /kg body weight of ethanolic extract of PHF protected rats against carbon tetrachloride liver injury by significant lowerering 5’ nucleotidase (5’NT), Gamma Glutamyl transferase (GGT), Glutamate dehdyrogenasse (GDH) and Succinate Dehydrogenase (SDH) levels compared to control. Normalization in these enzyme levels indicates strong hepatoprotective property of PHF extract.
Abstract: In this study rack systems that are structural storage
units of warehouses have been analyzed as structural with Finite
Element Method (FEA). Each cell of discussed rack system storages
pallets which have from 800 kg to 1000 kg weights and
0.80x1.15x1.50 m dimensions. Under this load, total deformations
and equivalent stresses of structural elements and principal stresses,
tensile stresses and shear stresses of connection elements have been
analyzed. The results of analyses have been evaluated according to
resistance limits of structural and connection elements. Obtained
results have been presented as visual and magnitude.
Abstract: In vitro gastro-duodenal digestion model was used to investigate the changes of emulsions under digestion conditions. Oil in water emulsions stabilized by whey proteins (2%) and stabilized by whey proteins (2%) with addition of carboxymethyl cellulose (0.75%) as gelling agent of continuous phase were prepared at pH7. Both emulsions were destabilized under gastric conditions; however the protective role of carboxymethyl cellulose was indicated by recording delay of fat digestibility of this emulsion. In the presence of carboxymethyl cellulose whey proteins on the interfacial surface of droplets were more resistant to gastric degradation causing limited hydrolysis of fat due to the poor acceptability of lipids for the enzymes. Studies of emulsions using in vivo model supported results from in vitro studies. Lower content of triglycerides in blood serum and higher amount of fecal fat of rats were determined when rats were fed by diet containing emulsion made with whey proteins and carboxymethyl cellulose.
Abstract: Real world Speaker Identification (SI) application
differs from ideal or laboratory conditions causing perturbations that
leads to a mismatch between the training and testing environment
and degrade the performance drastically. Many strategies have been
adopted to cope with acoustical degradation; wavelet based Bayesian
marginal model is one of them. But Bayesian marginal models
cannot model the inter-scale statistical dependencies of different
wavelet scales. Simple nonlinear estimators for wavelet based
denoising assume that the wavelet coefficients in different scales are
independent in nature. However wavelet coefficients have significant
inter-scale dependency. This paper enhances this inter-scale
dependency property by a Circularly Symmetric Probability Density
Function (CS-PDF) related to the family of Spherically Invariant
Random Processes (SIRPs) in Log Gabor Wavelet (LGW) domain
and corresponding joint shrinkage estimator is derived by Maximum
a Posteriori (MAP) estimator. A framework is proposed based on
these to denoise speech signal for automatic speaker identification
problems. The robustness of the proposed framework is tested for
Text Independent Speaker Identification application on 100 speakers
of POLYCOST and 100 speakers of YOHO speech database in three
different noise environments. Experimental results show that the
proposed estimator yields a higher improvement in identification
accuracy compared to other estimators on popular Gaussian Mixture
Model (GMM) based speaker model and Mel-Frequency Cepstral
Coefficient (MFCC) features.
Abstract: Mutations of the telomeric copy of the survival motor neuron 1 (SMN1) gene cause spinal muscular atrophy. A deletion of the Eef1a2 gene leads to lower motor neuron degeneration in wasted mice. Indirect evidences have been shown that the eEF1A protein family may interact with SMN, and our previous study showed that abnormalities of neuromuscular junctions in wasted mice were similar to those of Smn mutant mice. To determine potential colocalization between SMN and tissue-specific translation elongation factor 1A2 (eEF1A2), an immunochemical analysis of HeLa cells transfected with the plasmid pcDNA3.1(+)C-hEEF1A2- myc and a new quantitative test of colocalization by intensity correlation analysis (ICA) was used to explore the association of SMN and eEF1A2. Here the results showed that eEF1A2 redistributed from the cytoplasm to the nucleus in response to serum and epidermal growth factor. In the cytoplasm, compelling evidence showed that staining for myc-tagged eEF1A2 varied in synchrony with that for SMN, consistent with the formation of a SMN-eEF1A2 complex in the cytoplasm of HeLa cells. These findings suggest that eEF1A2 may colocalize with SMN in the cytoplasm and may be a component of the SMN complex. However, the limitation of the ICA method is an inability to resolve colocalization in components of small organelles such as the nucleus.
Abstract: This paper presents a new and efficient approach for capacitor placement in radial distribution systems that determine the optimal locations and size of capacitor with an objective of improving the voltage profile and reduction of power loss. The solution methodology has two parts: in part one the loss sensitivity factors are used to select the candidate locations for the capacitor placement and in part two a new algorithm that employs Plant growth Simulation Algorithm (PGSA) is used to estimate the optimal size of capacitors at the optimal buses determined in part one. The main advantage of the proposed method is that it does not require any external control parameters. The other advantage is that it handles the objective function and the constraints separately, avoiding the trouble to determine the barrier factors. The proposed method is applied to 9, 34, and 85-bus radial distribution systems. The solutions obtained by the proposed method are compared with other methods. The proposed method has outperformed the other methods in terms of the quality of solution.