Abstract: Ocimum americanum L (Lamiaceae) is an annual herb
that is native to tropical Africa. The in vitro and in vivo antioxidant
activity of its aqueous extract was carefully investigated by assessing
the DPPH radical scavenging activity, ABTS radical scavenging
activity and hydrogen peroxide radical scavenging activity. The
reducing power, total phenol, total flavonoids and flavonols content
of the extract were also evaluated. The data obtained revealed that the
extract is rich in polyphenolic compounds and scavenged the radicals
in a concentration dependent manner. This was done in comparison
with the standard antioxidants such as BHT and Vitamin C. Also, the
induction of oxidative damage with paracetamol (2000 mg/kg)
resulted in the elevation of lipid peroxides and significant (P < 0.05)
decrease in activities of superoxide dismutase, glutathione
peroxidase, glutathione reductase and catalase in the liver and kidney
of rats. However, the pretreatment of rats with aqueous extract of O.
americanum leaves (200 and 400 mg/kg) and silymarin (100 mg/kg)
caused a significant (P < 0.05) reduction in the values of lipid
peroxides and restored the levels of antioxidant parameters in these
organs. These findings suggest that the leaves of O. americanum have
potent antioxidant properties which may be responsible for its
acclaimed folkloric uses.
Abstract: Verification and Validation of Simulated Process
Model is the most important phase of the simulator life cycle.
Evaluation of simulated process models based on Verification and
Validation techniques checks the closeness of each component model
(in a simulated network) with the real system/process with respect to
dynamic behaviour under steady state and transient conditions. The
process of Verification and Validation helps in qualifying the process
simulator for the intended purpose whether it is for providing
comprehensive training or design verification. In general, model
verification is carried out by comparison of simulated component
characteristics with the original requirement to ensure that each step
in the model development process completely incorporates all the
design requirements. Validation testing is performed by comparing
the simulated process parameters to the actual plant process
parameters either in standalone mode or integrated mode.
A Full Scope Replica Operator Training Simulator for PFBR -
Prototype Fast Breeder Reactor has been developed at IGCAR,
Kalpakkam, INDIA named KALBR-SIM (Kalpakkam Breeder
Reactor Simulator) where in the main participants are
engineers/experts belonging to Modeling Team, Process Design and
Instrumentation & Control design team. This paper discusses about
the Verification and Validation process in general, the evaluation
procedure adopted for PFBR operator training Simulator, the
methodology followed for verifying the models, the reference
documents and standards used etc. It details out the importance of
internal validation by design experts, subsequent validation by
external agency consisting of experts from various fields, model
improvement by tuning based on expert’s comments, final
qualification of the simulator for the intended purpose and the
difficulties faced while co-coordinating various activities.
Abstract: Vegetation affects the mean and turbulent flow
structure. It may increase flood risks and sediment transport.
Therefore, it is important to develop analytical approaches for the bed
shear stress on vegetated bed, to predict resistance caused by
vegetation. In the recent years, experimental and numerical models
have both been developed to model the effects of submerged
vegetation on open-channel flow. In this paper, different analytic
models are compared and tested using the criteria of deviation, to
explore their capacity for predicting the mean velocity and select the
suitable one that will be applied in real case of rivers. The
comparison between the measured data in vegetated flume and
simulated mean velocities indicated, a good performance, in the case
of rigid vegetation, whereas, Huthoff model shows the best
agreement with a high coefficient of determination (R2=80%) and the
smallest error in the prediction of the average velocities.
Abstract: This study is used as a definition method to the value
and function in manufacturing sector. In concurrence of discussion
about present condition of modeling method, until now definition of
1D-CAE is ambiguity and not conceptual. Across all the physic fields,
those methods are defined with the formulation of differential
algebraic equation which only applied time derivation and simulation.
At the same time, we propose semi-acausal modeling concept and
differential algebraic equation method as a newly modeling method
which the efficiency has been verified through the comparison of
numerical analysis result between the semi-acausal modeling
calculation and FEM theory calculation.
Abstract: It has experimentally been proved that the
performance of compression ignition (C.I.) engine is spray
characteristics related. In modern diesel engine the spray formation
and the eventual combustion process are the vital processes that offer
more challenges towards enhancing the engine performance. In the
present work the numerical simulation has been carried out for
evaporating diesel sprays using Fluent software. For computational
fluid dynamics simulation “Meshing” is done using Gambit software
before transmitting it into Fluent. The simulation is carried out using
hot bomb conditions under varying chamber conditions such as gas
pressure, nozzle diameter and fuel injection pressure. For comparison
purpose, the numerical simulations the chamber conditions were kept
the same as that of the experimental data. At varying chamber
conditions the spray penetration rates are compared with the existing
experimental results.
Abstract: Fracture in hot precision forging of engine valves was
investigated in this paper. The entire valve forging procedure was
described and the possible cause of the fracture was proposed. Finite
Element simulation was conducted for the forging process, with
commercial Finite Element code DEFORMTM. The effects of
material properties, the effect of strain rate and temperature were
considered in the FE simulation. Two fracture criteria were discussed
and compared, based on the accuracy and reliability of the FE
simulation results. The selected criterion predicted the fracture
location and shows the trend of damage increasing with good
accuracy, which matches the experimental observation. Additional
modification of the punch shapes was proposed to further reduce the
tendency of fracture in forging. Finite Element comparison shows a
great potential of such application in the mass production.
Abstract: Leukaemia is a blood cancer disease that contributes
to the increment of mortality rate in Malaysia each year. There are
two main categories for leukaemia, which are acute and chronic
leukaemia. The production and development of acute leukaemia cells
occurs rapidly and uncontrollable. Therefore, if the identification of
acute leukaemia cells could be done fast and effectively, proper
treatment and medicine could be delivered. Due to the requirement of
prompt and accurate diagnosis of leukaemia, the current study has
proposed unsupervised pixel segmentation based on clustering
algorithm in order to obtain a fully segmented abnormal white blood
cell (blast) in acute leukaemia image. In order to obtain the
segmented blast, the current study proposed three clustering
algorithms which are k-means, fuzzy c-means and moving k-means
algorithms have been applied on the saturation component image.
Then, median filter and seeded region growing area extraction
algorithms have been applied, to smooth the region of segmented
blast and to remove the large unwanted regions from the image,
respectively. Comparisons among the three clustering algorithms are
made in order to measure the performance of each clustering
algorithm on segmenting the blast area. Based on the good sensitivity
value that has been obtained, the results indicate that moving kmeans
clustering algorithm has successfully produced the fully
segmented blast region in acute leukaemia image. Hence, indicating
that the resultant images could be helpful to haematologists for
further analysis of acute leukaemia.
Abstract: The aim of this work was to apply extractive
distillation for acetonitrile removal from water solutions, to validate
thermodynamic criterion based on excess Gibbs energy to entrainer
selection process for acetonitrile – water mixture separation and show
its potential efficiency at isothermal conditions as well as at isobaric
(conditions of real distillation process), to simulate and analyze an
extractive distillation process with chosen entrainers: optimize
amount of trays and feeds, entrainer/original mixture and reflux
ratios. Equimolar composition of the feed stream was chosen for the
process, comparison of the energy consumptions was carried out.
Glycerol was suggested as the most energetically and ecologically
suitable entrainer.
Abstract: Anthocyanins are natural pigments with effective UV
protection but their topical use could be limited due to their
physicochemical characteristics. An attempt to overcome such
limitations by complexation of 2 major anthocyanin-rich sources, C.
ternatea and Z. mays, has potentiated its use as topical antiinflammatory.
Cell studies indicate no cytotoxicity of the
anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and
human fore head fibroblasts by MTT. Croton oil-induced ear edema
in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a
topical anti-inflammatory in comparison to 0.5 mg/cm2 of
fluocinolone acetonide. Niosomal encapsulation of the AC
significantly prolonged the anti-inflammatory activity particularly at
8 h after topical application (p = 0.0001). The AC was not cytotoxic
and its anti-inflammatory and activity was dose-dependent and
prolonged by niosomal encapsulation. It has also shown to promote
collagen type 1 production in cell culture. Thus, AC could be a
potential candidate for topical anti-inflammatory agent from natural
resources.
Abstract: Rotary draw bending is a method which is being used
in tube forming. In the tube bending process, the neutral axis moves
towards the inner arc and the wall thickness distribution changes for
tube’s cross section. Thinning takes place in the outer arc of the tube
(extrados) due to the stretching of the material, whereas thickening
occurs in the inner arc of the tube (intrados) due to the comparison of
the material. The calculations of the wall thickness distribution,
neutral axis shifting, and strain distribution have not been accurate
enough, so far. The previous model (the geometrical model)
describes the neutral axis shifting and wall thickness distribution. The
geometrical of the tube, bending radius and bending angle are
considered in the geometrical model, while the influence of the
material properties of the tube forming are ignored. The advanced
model is a modification of the previous model using material
properties that depends on the correction factor. The correction factor
is a purely empirically determined factor. The advanced model was
compared with the Finite element simulation (FE simulation) using a
different bending factor (Bf =bending radius/ diameter of the tube),
wall thickness (Wf = diameter of the tube/ wall thickness), and
material properties (strain hardening exponent). Finite element model
of rotary draw bending has been performed in PAM-TUBE program
(version: 2012). Results from the advanced model resemble the FE
simulation and the experimental test.
Abstract: It is widely believed that mobile device is a promising technology for lending the opportunity for the third wave of electronic commerce. Mobile devices have changed the way companies do business. Many applications are under development or being incorporated into business processes. In this day, mobile applications are a vital component of any industry strategy.One of the greatest benefits of selling merchandise and providing services on a mobile application is that it widens a company’s customer base significantly.Mobile applications are accessible to interested customers across regional and international borders in different electronic business (e-business) area. But there is a dark side to this success story. The security risks associated with mobile devices and applications are very significant. This paper introduces a broad risk analysis for the various threats, vulnerabilities, and risks in mobile e-business applications and presents some important risk mitigation approaches. It reviews and compares two different frameworks for security assurance in mobile e-business applications. Based on the comparison, the paper suggests some recommendations for applications developers and business owners in mobile e-business application development process.
Abstract: In this study a ternary system containing sodium
chloride as solute, water as primary solvent and ethanol as the
antisolvent was considered to investigate the application of artificial
neural network (ANN) in prediction of sodium solubility in the
mixture of water as the solvent and ethanol as the antisolvent. The
system was previously studied using by Extended UNIQUAC model
by the authors of this study. The comparison between the results of
the two models shows an excellent agreement between them
(R2=0.99), and also approves the capability of ANN to predict the
thermodynamic behavior of ternary electrolyte systems which are
difficult to model.
Abstract: A thermosyphon system is a heat transfer loop which
operates on the basis of gravity and buoyancy forces. It guarantees a
good reliability and low maintenance cost as it does not involve any
mechanical pump. Therefore, it can be used in many industrial
applications such as refrigeration and air conditioning, electronic
cooling, nuclear reactors, geothermal heat extraction, etc. But flow
instabilities and loop configuration are the major problems in this
system. Several previous researchers studied that stabilities can be
suppressed by using nanofluids as loop fluid. In the present study a
rectangular thermosyphon loop with end heat exchangers are
considered for the study. This configuration is more appropriate for
many practical applications such as solar water heater, geothermal
heat extraction, etc. In the present work, steady-state analysis is
carried out on thermosyphon loop with parallel flow coaxial heat
exchangers at heat source and heat sink. In this loop nanofluid is
considered as the loop fluid and water is considered as the external
fluid in both hot and cold heat exchangers. For this analysis onedimensional
homogeneous model is developed. In this model,
conservation equations like conservation of mass, momentum, energy
are discretized using finite difference method. A computer code is
written in MATLAB to simulate the flow in thermosyphon loop. A
comparison in terms of heat transfer is made between water and
nanofluid as working fluids in the loop.
Abstract: In this paper a new algorithm to generate random
simple polygons from a given set of points in a two dimensional
plane is designed. The proposed algorithm uses a genetic algorithm to
generate polygons with few vertices. A new merge algorithm is
presented which converts any two polygons into a simple polygon.
This algorithm at first changes two polygons into a polygonal chain
and then the polygonal chain is converted into a simple polygon. The
process of converting a polygonal chain into a simple polygon is
based on the removal of intersecting edges. The experiments results
show that the proposed algorithm has the ability to generate a great
number of different simple polygons and has better performance in
comparison to celebrated algorithms such as space partitioning and
steady growth.
Abstract: The purpose of this paper is to examine gas transport
behavior of mixed matrix membranes (MMMs) combined with
porous particles. Main existing models are categorized in two main
groups; two-phase (ideal contact) and three-phase (non-ideal contact).
A new coefficient, J, was obtained to express equations for estimating
effect of the particle porosity in two-phase and three-phase models.
Modified models evaluates with existing models and experimental
data using Matlab software. Comparison of gas permeability of
proposed modified models with existing models in different MMMs
shows a better prediction of gas permeability in MMMs.
Abstract: Examining existing experimental results for shallow
rigid foundations subjected to vertical centric load (N), accompanied
or not with a bending moment (M), two main non-linear mechanisms
governing the cyclic response of the soil-foundation system can be
distinguished: foundation uplift and soil yielding. A soil-foundation
failure limit, is defined as a domain of resistance in the two
dimensional (2D) load space (N, M) inside of which lie all the
admissible combinations of loads; these latter correspond to a pure
elastic, non-linear elastic or plastic behavior of the soil-foundation
system, while the points lying on the failure limit correspond to a
combination of loads leading to a failure of the soil-foundation
system. In this study, the proposed resistance domain is constructed
analytically based on mechanics. Original elastic limit, uplift
initiation limit and iso-uplift limits are constructed inside this
domain. These limits give a prediction of the mechanisms activated
for each combination of loads applied to the foundation. A
comparison of the proposed failure limit with experimental tests
existing in the literature shows interesting results. Also, the
developed uplift initiation limit and iso-uplift curves are confronted
with others already proposed in the literature and widely used due to
the absence of other alternatives, and remarkable differences are
noted, showing evident errors in the past proposals and relevant
accuracy for those given in the present work.
Abstract: Proof of controlling crack width is a basic condition
for securing suitable performance in serviceability limit state. The
cracking in concrete can occur at any time from the casting of time to
the years after the concrete has been set in place. Most codes struggle
with offering procedure for crack width calculation. There is lack in
availability of design charts for designers to compute crack width
with ease. The focus of the study is to utilize design charts and
parametric equations in calculating crack width with minimum error.
The paper contains a simplified procedure to calculate crack width
for reinforced concrete (RC) sections subjected to bending with axial
tensile force following the guidelines of Euro code [DS EN-1992-1-1
& DS EN-1992-1-2]. Numerical examples demonstrate the
application of the suggested procedure. Comparison with parallel
analytical tools supports the validity of result and show the
percentage deviation of crack width in both the procedures. The
technique is simple, user friendly and ready to evolve for a greater
spectrum of section sizes and materials.
Abstract: Presently, engine cooling pump is driven by toothed
belt. Therefore, the pump speed is dependent on engine speed which
varies their output. At normal engine operating conditions (Higher
RPM and low load, Higher RPM and high load), mechanical water
pumps in existing engines are inevitably oversized and so the use of
an electric water pump together with state-of-the-art thermal
management of the combustion engine has measurable advantages.
Demand-driven cooling, particularly in the cold-start phase, saves
fuel (approx 3 percent) and leads to a corresponding reduction in
emissions. The lack of dependence on a mechanical drive also results
in considerable flexibility in component packaging within the engine
compartment. This paper describes the testing and comparison of
existing mechanical water pump with that of the electric water pump.
When the existing mechanical water pump is replaced with the new
electric water pump the percentage gain in system efficiency is also
discussed.
Abstract: It is difficult to study the effect of various variables on
cycle fitting through actual experiment. To overcome such difficulty,
the forward dynamics of a musculoskeletal model was applied to cycle
fitting in this study. The measured EMG data weres compared with the
muscle activities of the musculoskeletal model through forward
dynamics. EMG data were measured from five cyclists who do not
have musculoskeletal diseases during three minutes pedaling with a
constant load (150 W) and cadence (90 RPM). The muscles used for
the analysis were the Vastus Lateralis (VL), Tibialis Anterior (TA),
Bicep Femoris (BF), and Gastrocnemius Medial (GM). Person’s
correlation coefficients of the muscle activity patterns, the peak timing
of the maximum muscle activities, and the total muscle activities were
calculated and compared. BIKE3D model of AnyBody (Anybodytech,
Denmark) was used for the musculoskeletal model simulation. The
comparisons of the actual experiments with the simulation results
showed significant correlations in the muscle activity patterns (VL:
0.789, TA: 0.503, BF: 0.468, GM: 0.670). The peak timings of the
maximum muscle activities were distributed at particular phases. The
total muscle activities were compared with the normalized muscle
activities, and the comparison showed about 10% difference in the VL
(+10%), TA (+9.7%), and BF (+10%), excluding the GM (+29.4%).
Thus, it can be concluded that muscle activities of model &
experiment showed similar results. The results of this study indicated
that it was possible to apply the simulation of further improved
musculoskeletal model to cycle fitting.
Abstract: This paper identifies limitations of existing two e-
Governance services viz. railway ticket booking and passport service
in India. The comparison has been made as to how in the past these
two citizen services were operating manually and how these services
are taken online via e-Governance. Different e-Governance projects,
investment aspects, and role of corporate are discussed. For Indian
Railway online ticketing a comparison has been made between state
run booking website and popular private firm run booking websites.
For passport service, observations through personal visit to passport
center is described. Suggestions are made to improve these services
further to improve citizen service experiences.