Abstract: The interaction of tunneling or mining with
groundwater has become a very relevant problem not only due to the
need to guarantee the safety of workers and to assure the efficiency of
the tunnel drainage systems, but also to safeguard water resources
from impoverishment and pollution risk. Therefore it is very
important to forecast the drainage processes (i.e., the evaluation of
drained discharge and drawdown caused by the excavation). The aim
of this study was to know better the system and to quantify the flow
drained from the Fontane mines, located in Val Germanasca (Turin,
Italy). This allowed to understand the hydrogeological local changes
in time. The work has therefore been structured as follows: the
reconstruction of the conceptual model with the geological,
hydrogeological and geological-structural study; the calculation of
the tunnel inflows (through the use of structural methods) and the
comparison with the measured flow rates; the water balance at the
basin scale. In this way it was possible to understand what are the
relationships between rainfall, groundwater level variations and the
effect of the presence of tunnels as a means of draining water.
Subsequently, it the effects produced by the excavation of the mining
tunnels was quantified, through numerical modeling. In particular,
the modeling made it possible to observe the drawdown variation as a
function of number, excavation depth and different mines linings.
Abstract: This paper presents an experimental investigation on
the machinability of laser-sintered material using small ball end mill focusing on wear mechanisms. Laser-sintered material was produced
by irradiating a laser beam on a layer of loose fine SCM-Ni-Cu powder. Bulk carbon steel JIS S55C was selected as a reference steel.
The effects of powder consolidation mechanisms and unsintered
powder on the tool life and wear mechanisms were carried out. Results indicated that tool life in cutting laser-sintered material is
lower than that in cutting JIS S55C. Adhesion of the work material and chipping were the main wear mechanisms of the ball end mill in
cutting laser-sintered material. Cutting with the unsintered powder
surrounding the tool and laser-sintered material had caused major fracture on the cutting edge.
Abstract: Human genome is not only the evolutionary
summation of all advantageous events, but also houses lesions of
deleterious foot prints. A single gene mutation sometimes may
express multiple consequences in numerous tissues and a linear
relationship of the genotype and the phenotype may often be obscure.
ß Thalassemia minor, a transfusion independent mild anaemia,
coupled with environment among other factors may articulate into
phenotypic pleotropy with Hypocholesterolemia, Vitamin D
deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological
alterations. Occurrence of Pancreatic insufficiency, resultant
steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with
Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor
patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2
4.60% and Hb Adult 84.80% and altered Hemogram) with increased
Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2
(9.5mg/ml) indicate towards a cascade of phenotypic pleotropy
where the ß Thalassemia mutation ,be it in the 5’ cap site of the
mRNA , differential splicing etc in heterozygous state is effecting
several metabolic pathways. Compensatory extramedulary
hematopoiesis may not coped up well with the stressful life style of
the young individual and increased erythropoietic stress with high
demand for cholesterol for RBC membrane synthesis may have
resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia
may have caused the pancreatic insufficiency, leading to Vitamin D
deficiency. This may in turn have caused the secondary
hyperparathyroidism to sustain serum Calcium level. Irritability and
stress intolerance of the patient was a cumulative effect of the vicious
cycle of metabolic compromises. From these findings we propose
that the metabolic deficiencies in the ß Thalassemia mutations may
be considered as the phenotypic display of the pleotropy to explain
the genetic epidemiology.
According to the recommendations from the NIH Workshop on
Gene-Environment Interplay in Common Complex Diseases: Forging
an Integrative Model, study design of observations should be
informed by gene-environment hypotheses and results of a study
(genetic diseases) should be published to inform future hypotheses.
Variety of approaches is needed to capture data on all possible
aspects, each of which is likely to contribute to the etiology of
disease. Speakers also agreed that there is a need for development of
new statistical methods and measurement tools to appraise
information that may be missed out by conventional method where
large sample size is needed to segregate considerable effect.
A meta analytic cohort study in future may bring about significant
insight on to the title comment.
Abstract: This paper aims to study decomposition behavior in
pyrolytic environment of four lignocellulosic biomass (oil palm shell,
oil palm frond, rice husk and paddy straw), and two commercial
components of biomass (pure cellulose and lignin), performed in a
thermogravimetry analyzer (TGA). The unit which consists of a
microbalance and a furnace flowed with 100 cc (STP) min-1 Nitrogen,
N2 as inert. Heating rate was set at 20⁰C min-1 and temperature
started from 50 to 900⁰C. Hydrogen gas production during the
pyrolysis was observed using Agilent Gas Chromatography Analyzer
7890A. Oil palm shell, oil palm frond, paddy straw and rice husk
were found to be reactive enough in a pyrolytic environment of up to
900°C since pyrolysis of these biomass starts at temperature as low as
200°C and maximum value of weight loss is achieved at about
500°C. Since there was not much different in the cellulose,
hemicelluloses and lignin fractions between oil palm shell, oil palm
frond, paddy straw and rice husk, the T-50 and R-50 values obtained
are almost similar. H2 productions started rapidly at this temperature
as well due to the decompositions of biomass inside the TGA.
Biomass with more lignin content such as oil palm shell was found to
have longer duration of H2 production compared to materials of high
cellulose and hemicelluloses contents.
Abstract: In the upstream we place a piece of ring and rotate
it with 83Hz, 166Hz, 333Hz,and 666H to find the effect of the
periodic distortion.In the experiment this type of the perturbation
will not allow since the mechanical failure of any parts of the
equipment in the upstream will destroy the blade system. This type of
study will be only possible by CFD. We use two pumps NS32
(ENSAM) and three blades pump (Tamagawa Univ). The benchmark
computations were performed without perturbation parts, and confirm
the computational results well agreement in head-flow rate. We
obtained the pressure fluctuation growth rate that is representing the
global instability of the turbo-system. The fluctuating torque
components were 0.01Nm(5000rpm), 0.1Nm(10000rmp),
0.04Nm(20000rmp), 0.15Nm( 40000rmp) respectively. Only for
10000rpm(166Hz) the output toque was random, and it implies that it
creates unsteady flow by separations on the blades, and will reduce the
pressure loss significantly
Abstract: Since the beginning of human history, human
activities have caused many changes in the environment. Today, a
particular attention should be paid to gaining knowledge about water
quality of wetlands which are pristine natural environments rich in
genetic reserves. If qualitative conditions of industrial areas (in terms
of both physicochemical and biological conditions) are not addressed
properly, they could cause disruption in natural ecosystems,
especially in rivers. With regards to the quality of water resources,
determination of pollutant sources plays a pivotal role in engineering
projects as well as designing water quality control systems. Thus,
using different methods such as flow duration curves, dischargepollution
load model and frequency analysis by HYFA software
package, risk of various industrial pollutants in international and
ecologically important Gavkhoni wetland is analyzed. In this study, a
station located at Varzaneh City is used as the last station on
Zayanderud River, from where the river water is discharged into the
wetland. Results showed that elements- concentrations often
exceeded the allowed level and river water can endanger regional
ecosystem. In addition, if the river discharge is managed on Q25
basis, this basis can lower concentrations of elements, keeping them
within the normal level.
Abstract: This paper presents the prediction of kidney
dysfunction using different neural network (NN) approaches. Self
organization Maps (SOM), Probabilistic Neural Network (PNN) and
Multi Layer Perceptron Neural Network (MLPNN) trained with Back
Propagation Algorithm (BPA) are used in this study. Six hundred and
sixty three sets of analytical laboratory tests have been collected from
one of the private clinical laboratories in Baghdad. For each subject,
Serum urea and Serum creatinin levels have been analyzed and tested
by using clinical laboratory measurements. The collected urea and
cretinine levels are then used as inputs to the three NN models in
which the training process is done by different neural approaches.
SOM which is a class of unsupervised network whereas PNN and
BPNN are considered as class of supervised networks. These
networks are used as a classifier to predict whether kidney is normal
or it will have a dysfunction. The accuracy of prediction, sensitivity
and specificity were found for each type of the proposed networks
.We conclude that PNN gives faster and more accurate prediction of
kidney dysfunction and it works as promising tool for predicting of
routine kidney dysfunction from the clinical laboratory data.
Abstract: A company CSR commitment, as stated in its Social
Report is, actually, perceived by its stakeholders?And in what
measure? Moreover, are stakeholders satisfied with the company
CSR efforts? Indeed, business returns from Corporate Social
Responsibility (CSR) practices, such as company reputation and
customer loyalty, depend heavily on how stakeholders perceive the
company social conduct. In this paper, we propose a methodology to
assess a company CSR commitment based on Global Reporting
Initiative (GRI) indicators, Content Analysis and a CSR positioning
matrix. We evaluate three aspects of CSR: the company commitment
disclosed through its Social Report; the company commitment
perceived by its stakeholders; the CSR commitment that stakeholders
require to the company. The positioning of the company under study
in the CSR matrix is based on the comparison among the three
commitment aspects (disclosed, perceived, required) and it allows
assessment and development of CSR strategies.
Abstract: The objective of this paper is twofold: (1) discuss and
analyze the successful case studies worldwide, and (2) identify the
similarities and differences of case studies worldwide. Design
methodology/approach: The nature of this research is mainly method
qualitative (multi-case studies, literature review). This investigation
uses ten case studies, and the data was mainly collected and
organizational documents from the international countries. Finding:
The finding of this research can help incubator manager, policy
maker and government parties for successful implementation.
Originality/value: This paper contributes to the current literate review
on the best practices worldwide. Additionally, it presents future
perspective for academicians and practitioners.
Abstract: The Maximum Weighted Independent Set (MWIS)
problem is a classic graph optimization NP-hard problem. Given an
undirected graph G = (V, E) and weighting function defined on the
vertex set, the MWIS problem is to find a vertex set S V whose total
weight is maximum subject to no two vertices in S are adjacent. This
paper presents a novel approach to approximate the MWIS of a graph
using minimum weighted vertex cover of the graph. Computational
experiments are designed and conducted to study the performance
of our proposed algorithm. Extensive simulation results show that
the proposed algorithm can yield better solutions than other existing
algorithms found in the literature for solving the MWIS.
Abstract: In this paper, we study the application of Extreme
Learning Machine (ELM) algorithm for single layered feedforward
neural networks to non-linear chaotic time series problems. In this
algorithm the input weights and the hidden layer bias are randomly
chosen. The ELM formulation leads to solving a system of linear
equations in terms of the unknown weights connecting the hidden
layer to the output layer. The solution of this general system of
linear equations will be obtained using Moore-Penrose generalized
pseudo inverse. For the study of the application of the method we
consider the time series generated by the Mackey Glass delay
differential equation with different time delays, Santa Fe A and
UCR heart beat rate ECG time series. For the choice of sigmoid,
sin and hardlim activation functions the optimal values for the
memory order and the number of hidden neurons which give the
best prediction performance in terms of root mean square error are
determined. It is observed that the results obtained are in close
agreement with the exact solution of the problems considered
which clearly shows that ELM is a very promising alternative
method for time series prediction.
Abstract: Bioinformatics and Cheminformatics use computer as disciplines providing tools for acquisition, storage, processing, analysis, integrate data and for the development of potential applications of biological and chemical data. A chemical database is one of the databases that exclusively designed to store chemical information. NMRShiftDB is one of the main databases that used to represent the chemical structures in 2D or 3D structures. SMILES format is one of many ways to write a chemical structure in a linear format. In this study we extracted Antimicrobial Structures in SMILES format from NMRShiftDB and stored it in our Local Data Warehouse with its corresponding information. Additionally, we developed a searching tool that would response to user-s query using the JME Editor tool that allows user to draw or edit molecules and converts the drawn structure into SMILES format. We applied Quick Search algorithm to search for Antimicrobial Structures in our Local Data Ware House.
Abstract: The present study attempted to improve the Mercury
(Hg) sorption capacity of kanuma volcanic ash soil (KVAS) by
impregnating the cupper (Cu). Impregnation was executed by 1 and
5% Cu powder and sorption characterization of optimum Hg
removing Cu impregnated KVAS was performed under different
operational conditions, contact time, solution pH, sorbent dosage and
Hg concentration using the batch operation studies. The 1% Cu
impregnated KVAS pronounced optimum improvement (79%) in
removing Hg from water compare to control. The present
investigation determined the equilibrium state of maximum Hg
adsorption at 6 h contact period. The adsorption revealed a pH
dependent response and pH 3.5 showed maximum sorption capacity
of Hg. Freundlich isotherm model is well fitted with the experimental
data than that of Langmuir isotherm. It can be concluded that the Cu
impregnation improves the Hg sorption capacity of KVAS and 1%
Cu impregnated KVAS could be employed as cost-effective
adsorbent media for treating Hg contaminated water.
Abstract: This research aimed to study on the potential of
recycling organic waste in Suan Sunandha Rajabhat University as
compost. In doing so, the composition of solid waste generated in the
campus was investigated while physical and chemical properties of
organic waste were analyzed in order to evaluate the portion of waste
suitable for recycling as compost. As a result of the study, it was
found that (1) the amount of organic waste was averaged at 299.8
kg/day in which mixed food wastes had the highest amount of 191.9
kg/day followed by mixed leave & yard wastes and mixed fruit &
vegetable wastes at the amount of 66.3 and 41.6 kg/day respectively;
(2) physical and chemical properties of organic waste in terms of
moisture content was between 69.54 to 78.15%, major elements for
plant as N, P and K were 0.14 to 0.17%, 0.46 to 0.52% and 0.16 to
0.18% respectively, and carbon/nitrogen ratio (C/N) was about 15:1
to 17.5:1; (3) recycling organic waste as compost was designed by
aerobic decomposition using mixed food wastes : mixed leave & yard
wastes : mixed fruit & vegetable wastes at the portion of 3:2:1 by
weight in accordance with the potential of their amounts and their
physical and chemical properties.
Abstract: Yogurt is a coagulated milk product obtained from
the lactic acid fermentation by the action of Lactobacillus
bulgaricus and Streptococcus thermophilus. The additions of fruits
into milk may enhance the taste and the therapeutical values of milk
products. However fruits also may change the fermentation
behaviour. In this present study, the changes in physicochemical, the
peptide concentration, total phenolics content and the antioxidant
potential of yogurt upon the addition of Hylocereus polyrhizus and
Hylocereus undatus (white and red dragon fruit) were investigated.
Fruits enriched yogurt (10%, 20%, 30% w/w) were prepared and the
pH, TTA, syneresis measurement, peptide concentration, total
phenolics content and DPPH antioxidant inhibition percentage were
determined. Milk fermentation rate was enhanced in red dragon fruit
yogurt for all doses (-0.3606 - -0.4126 pH/h) while only white
dragon fruit yogurt with 20% and 30% (w/w) composition showed
increment in fermentation rate (-0.3471 - -0.3609 pH/h) compared to
plain yogurt (-0.3369pH/h). All dragon fruit enriched yogurts
generally showed lower pH readings (pH 3.95 - 4.03) compared to
plain yogurt (pH 4.05). Both fruit yogurts showed a higher lactic
acid percentage (1.14-1.23%) compared to plain yogurt (1.08%).
Significantly higher syneresis percentage (57.19 - 70.32%)
compared to plain yogurt (52.93%) were seen in all fruit enriched
yogurts. The antioxidant activity of plain yogurt (19.16%) was
enhanced by the presence of white and red dragon fruit (24.97-
45.74%). All fruit enriched yogurt showed an increment in total
phenolic content (36.44 - 64.43mg/ml) compared to plain yogurt
(20.25mg/ml). However, the addition of white and red dragon fruit
did not enhance the proteolysis of milk during fermentation.
Therefore, it could be concluded that the addition of white and red
dragon fruit into yogurt enhanced the milk fermentation rate, lactic
acid content, syneresis percentage, antioxidant activity, and total
phenolics content in yogurt.
Abstract: This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p
Abstract: The study of piezoelectric material in the past was in
T-Domain form; however, no one has studied piezoelectric material in the S-Domain form. This paper will present the piezoelectric material in the transfer function or S-Domain model. S-Domain is a
well known mathematical model, used for analyzing the stability of the material and determining the stability limits. By using S-Domain
in testing stability of piezoelectric material, it will provide a new tool for the scientific world to study this material in various forms.
Abstract: Organochlorine pesticides (OCPs) are known to be
persistent and bioaccumulative toxicants that may cause reproductive
impairments in wildlife as well as human. The current study uses the
snail-eating turtle Malayemys macrocephala, a long-lived animal
commonly distribute in rice field habitat in central part of Thailand,
as a sentinel to monitor OCP contamination in environment. The
nest soil, complete clutch of eggs, and blood of the turtle were
collected from agricultural areas in the Chao Phraya River Basin,
Thailand during the nesting season of 2007-2008. The novel
methods for tissue extraction by an accelerated solvent extractor
(ASE, for egg) and liquid-liquid extraction (for blood) have been
developed. The nineteen OCP residues were analyzed by gas
chromatography with micro-electron captured detector (GC-μECD).
The validated methods have met requirements of the AOAC
standard. The results indicated that significant amounts of OCPs are
still contaminated in nest soil and eggs of the turtle even though the
OCPs had been banned in this area for many years. This suggested
the potential risk to health of wildlife as well as human in the area.
Abstract: In this paper we discuss a set of guidelines which
could be adapted when designing an audio user interface for the
visually impaired. It is based on an audio environment that is
focused on audio positioning. Unlike current applications which only
interpret Graphical User Interface (GUI) for the visually impaired,
this particular audio environment bypasses GUI to provide a direct
auditory output. It presents the capability of two dimensional (2D)
navigation on audio interfaces. This paper highlights the significance
of a 2D audio environment with spatial information in the context
of the visually impaired. A thorough usability study has been conducted
to prove the applicability of proposed design guidelines for
these auditory interfaces. While proving these guidelines, previously
unearthed design aspects have been revealed in this study.
Abstract: A pilot project was carried out in 2007 by the senior
students of Cyprus International University, aiming to minimize the
total cost of waste collection in Northern Cyprus. Many developed
and developing countries have cut their transportation costs – which
lies between 30-40% – down at a rate of 40% percent, by
implementing network models for their route assignments.
Accordingly, a network model was implemented at Göçmenköy
district, to optimize and standardize waste collection works. The
work environment of the employees were also redesigned to provide
maximum ergonomy and to increase productivity, efficiency and
safety. Following the collection of the required data including waste
densities, lengths of roads and population, a model was constructed
to allocate the optimal route assignment for the waste collection
trucks at Göçmenköy district.