Abstract: An exploration in the competency of the optical
multilevel Mapping Multiplexing Technique (MMT) system in
tolerating to the impact of nonlinearities as Self Phase Modulation
(SPM) during the presence of dispersion compensation methods. The
existence of high energy pulses stimulates deterioration in the chirp
compression process attained by SPM which introduces an upper
power boundary limit. An evaluation of the post and asymmetric prepost
fiber compensation methods have been deployed on the MMT
system compared with others of the same bit rate modulation formats.
The MMT 40 Gb/s post compensation system has 1.4 dB
enhancements to the 40 Gb/s 4-Arysystem and less than 3.9 dB
penalty compared to the 40 Gb/s OOK-RZsystem. However, the
optimized Pre-Post asymmetric compensation has an enhancement of
4.6 dB compared to the Post compensation MMT configuration for a
30% pre compensation dispersion.
Abstract: In this paper the authors present the framework of a
system for assisting users through counseling on personal health, the
Personal Health Assistance Service Expert System (PHASES).
Personal health assistance systems need Personal Health Records
(PHR), which support wellness activities, improve the understanding
of personal health issues, enable access to data from providers of
health services, strengthen health promotion, and in the end improve
the health of the population. This is especially important in societies
where the health costs increase at a higher rate than the overall
economy. The most important elements of a healthy lifestyle are
related to food (such as balanced nutrition and diets), activities for
body fitness (such as walking, sports, fitness programs), and other
medical treatments (such as massage, prescriptions of drugs). The
PHASES framework uses an ontology of food, which includes
nutritional facts, an expert system keeping track of personal health
data that are matched with medical treatments, and a comprehensive
data transfer between patients and the system.
Abstract: The persistent nature of perfluorochemicals (PFCs) has attracted global concern in recent years. Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) are the most commonly found PFC compounds, and thus their fate and transport play key roles in PFC distribution in the natural environment. The kinetic behavior of PFOS or PFOA on boehmite consists of a fast adsorption process followed by a slow adsorption process which may be attributed to the slow transport of PFOS or PFOA into the boehmite pore surface. The adsorption isotherms estimated the maximum adsorption capacities of PFOS and PFOA on boehmite as 0.877 μg/m2 and 0.633 μg/m2, with the difference primarily due to their different functional groups. The increase of solution pH led to a moderate decrease of PFOS and PFOA adsorption, owing to the increase of ligand exchange reactions and the decrease of electrostatic interactions. The presence of NaCl in solution demonstrated negative effects for PFOS and PFOA adsorption on boehmite surfaces, with potential mechanisms being electrical double layer compression, competitive adsorption of chloride.
Abstract: Computational techniques derived from digital image processing are playing a significant role in the security and digital copyrights of multimedia and visual arts. This technology has the effect within the domain of computers. This research presents discrete M-band wavelet transform (MWT) and cosine transform (DCT) based watermarking algorithm by incorporating the principal component analysis (PCA). The proposed algorithm is expected to achieve higher perceptual transparency. Specifically, the developed watermarking scheme can successfully resist common signal processing, such as geometric distortions, and Gaussian noise. In addition, the proposed algorithm can be parameterized, thus resulting in more security. To meet these requirements, the image is transformed by a combination of MWT & DCT. In order to improve the security further, we randomize the watermark image to create three code books. During the watermark embedding, PCA is applied to the coefficients in approximation sub-band. Finally, first few component bands represent an excellent domain for inserting the watermark.
Abstract: The purpose of this work was to inspect the potential
of vincristine-dextran complex loaded solid lipid nanoparticles for
drug delivery to the brain.
The nanoparticles were stained with a fluorescence dye and their
plasma pharmacokinetic and brain concentrations were investigated
following injection to rats.
The result revealed a significant improvement in the plasma
concentration profile of the SLN injected animals as well as a sharp
increased concentration in the brains.
Abstract: Metrics is the process by which numbers or symbols
are assigned to attributes of entities in the real world in such a way as
to describe them according to clearly defined rules. Software metrics
are instruments or ways to measuring all the aspect of software
product. These metrics are used throughout a software project to
assist in estimation, quality control, productivity assessment, and
project control. Object oriented software metrics focus on
measurements that are applied to the class and other characteristics.
These measurements convey the software engineer to the behavior of
the software and how changes can be made that will reduce
complexity and improve the continuing capability of the software.
Object oriented software metric can be classified in two types static
and dynamic. Static metrics are concerned with all the aspects of
measuring by static analysis of software and dynamic metrics are
concerned with all the measuring aspect of the software at run time.
Major work done before, was focusing on static metric. Also some
work has been done in the field of dynamic nature of the software
measurements. But research in this area is demanding for more work.
In this paper we give a set of dynamic metrics specifically for
polymorphism in object oriented system.
Abstract: Language Reforms and potential use of ICTs has been a focal area of Higher Education Commission of Pakistan. Efforts are being accelerated to incorporate fast expanding ICTs to bring qualitative improvement in language instruction in higher education. This paper explores how university teachers are benefitting from ICTs to make their English class effective and what type of problems they face in practicing ICTs during their lectures. An in-depth qualitative study was employed to understand why language teachers tend to use ICTs in their instruction and how they are practicing it. A sample of twenty teachers from five universities located in Islamabad, three from public sector and two from private sector, was selected on non-random (Snowball) sampling basis. An interview with 15 semi-structured items was used as research instruments to collect data. The findings reveal that business English teaching is facilitated and improved through the use of ICTs. The language teachers need special training regarding the practices and implementation of ICTs. It is recommended that initiatives might be taken to equip university language teachers with modern methodology incorporating ICTs as focal area and efforts might be made to remove barriers regarding the training of language teachers and proper usage of ICTs.
Abstract: In wireless and mobile communications, this progress
provides opportunities for introducing new standards and improving
existing services. Supporting multimedia traffic with wireless networks
quality of service (QoS). In this paper, a grey-fuzzy controller for radio
resource management (GF-RRM) is presented to maximize the number
of the served calls and QoS provision in wireless networks. In a
wireless network, the call arrival rate, the call duration and the
communication overhead between the base stations and the control
center are vague and uncertain. In this paper, we develop a method to
predict the cell load and to solve the RRM problem based on the
GF-RRM, and support the present facility has been built on the
application-level of the wireless networks. The GF-RRM exhibits the
better adaptability, fault-tolerant capability and performance than other
algorithms. Through simulations, we evaluate the blocking rate, update
overhead, and channel acquisition delay time of the proposed method.
The results demonstrate our algorithm has the lower blocking rate, less
updated overhead, and shorter channel acquisition delay.
Abstract: The fast growth in complexity coupled with requests for shorter development periods for embedded systems are bringing demands towards a more effective, i.e. higher-abstract, design process for hardaware/software integrated design. In Software Engineering area, Model Driven Architecture (MDA) and Executable UML (xUML) has been accepted to bring further improvement in software design. This paper constructs MDA and xUML stepwise transformations from an abstract specification model to a more concrete implementation model using the refactoring technique for hardaware/software integrated design. This approach provides clear and structured models which enables quick exploration and synthesis, and early stage verification.
Abstract: Severe heart failure is a common problem that has a significant effect on health expenditures in industrialized countries; moreover it reduces patient-s quality of life. However, current research usually focuses either on detailed modeling of the heart or on detailed modeling of the cardiovascular system. Thus, this paper aims to present a sophisticated model of the heart enhanced with an extensive model of the cardiovascular system. Special interest is on the pressure and flow values close to the heart since these values are critical to accurately diagnose causes of heart failure. The model is implemented in Dymola an object-oriented, physical modeling language. Results achieved with the novel model show overall feasibility of the approach. Moreover, results are illustrated and compared to other models. The novel model shows significant improvements.
Abstract: Hybrid photovoltaic thermal (PV/T) solar system comprises a solar collector which is disposed on photovoltaic solar cells. The disadvantage of a conventional photovoltaic cell is that its performance decreases as the temperature increases. Indeed, part of the solar radiation is converted into electricity and is dissipated as heat, increasing the temperature of the photovoltaic cell with respect to the ambient temperature. The objective of this work is to study experimentally and implement a hybrid prototype to evaluate electrical and thermal performance. In this paper, an experimental study of two new configurations of hybrid collectors is exposed. The results are given and interpreted. The two configurations of absorber studied are a new combination with tubes and galvanized tank, the other is a tubes and sheet.
Abstract: Increasing user comfort and reducing operation costs
have always been primary objectives of lighting control strategies in a
building. This paper proposes an architecture of the lighting control
system for a daylit office. The system consists of the lighting
controller, A/D & D/A converter, dimmable LED lights, and the
lighting management software. Verification tests are conducted using
the proposed system specialized for the interior lighting of a open-plan
office. The results showed the proposed architecture of the lighting
system would improve the overall system reliability, lower the system
cost, and provide ease of installation and maintenance.
Abstract: Objective: The objective of this paper is to assess the
hospitals preparedness for emergency using WHO standards.
Method: This is a cross-sectional study, consisted of site visit,
questionnaire survey, 16 health facilities were included. The WHO
standard for emergency preparedness of health facilities was used to
evaluate and assess the hospitals preparedness of health facilities.
Result: 13 hospitals were responded. They scored below average
in all measure >75%), while above average score was in 7 out 9 nine
measure with a range of 8%-25%. Un acceptable below average was
noted in two measures only.
Discussion: The biggest challenge facing the hospitals in their
emergency intervention is the lack of pre-emergency and emergency
preparedness plans as well as the coordination of the hospitals
response mechanisms.
Conclusion: The studied hospitals presently are far from
international disasters preparedness protocols. That necessitates
improvements in emergency preparedness, as well as in physician
skills for injury management.
Abstract: In this paper, the shape design process is briefly discussed emphasizing the use of topology optimization in the conceptual design stage. The basic idea is to view feasible domains for sensitivity region concepts. In this method, the main process consists of two steps: as the design moves further inside the feasible domain using Taguchi method, and thus becoming more successful topology optimization, the sensitivity region becomes larger. In designing a double-eccentric butterfly valve, related to hydrodynamic performance and disc structure, are discussed where the use of topology optimization has proven to dramatically improve an existing design and significantly decrease the development time of a shape design. Computational Fluid Dynamics (CFD) analysis results demonstrate the validity of this approach.
Abstract: Severe acute respiratory syndrome (SARS) is a respiratory disease in humans which is caused by the SARS coronavirus. The treatment of coronavirus-associated SARS has been evolving and so far there is no consensus on an optimal regimen. The mainstream therapeutic interventions for SARS involve broad-spectrum antibiotics and supportive care, as well as antiviral agents and immunomodulatory therapy. The Protein- Ligand interaction plays a significant role in structural based drug designing. In the present work we have taken the receptor Angiotensin converting enzyme 2 and identified the drugs that are commonly used against SARS. They are Lopinavir, Ritonavir, Ribavirin, and Oseltamivir. The receptor Angiotensin converting enzyme 2 (ACE-2) was docked with above said drugs and the energy value obtained are as follows, Lopinavir (-292.3), Ritonavir (-325.6), Oseltamivir (- 229.1), Ribavirin (-208.8). Depending on the least energy value we have chosen the best two drugs out of the four conventional drugs. We tried to improve the binding efficiency and steric compatibility of the two drugs namely Ritonavir and Lopinavir. Several modifications were made to the probable functional groups (phenylic, ketonic groups in case of Ritonavir and carboxylic groups in case of Lopinavir respectively) which were interacting with the receptor molecule. Analogs were prepared by Marvin Sketch software and were docked using HEX docking software. Lopinavir analog 8 and Ritonavir analog 11 were detected with significant energy values and are probable lead molecule. It infers that some of the modified drugs are better than the original drugs. Further work can be carried out to improve the steric compatibility of the drug based upon the work done above for a more energy efficient binding of the drugs to the receptor.
Abstract: The occurrence and removal of trace organic
contaminants in the aquatic environment has become a focus of
environmental concern. For the selective removal of carbamazepine
from loaded waters molecularly imprinted polymers (MIPs) were
synthesized with carbamazepine as template. Parameters varied were
the type of monomer, crosslinker, and porogen, the ratio of starting
materials, and the synthesis temperature. Best results were obtained
with a template to crosslinker ratio of 1:20, toluene as porogen, and
methacrylic acid (MAA) as monomer. MIPs were then capable to
recover carbamazepine by 93% from a 10-5 M landfill leachate
solution containing also caffeine and salicylic acid. By comparison,
carbamazepine recoveries of 75% were achieved using a nonimprinted
polymer (NIP) synthesized under the same conditions, but
without template. In landfill leachate containing solutions
carbamazepine was adsorbed by 93-96% compared with an uptake of
73% by activated carbon. The best solvent for desorption was
acetonitrile, with which the amount of solvent necessary and dilution
with water was tested. Selected MIPs were tested for their reusability
and showed good results for at least five cycles. Adsorption
isotherms were prepared with carbamazepine solutions in the
concentration range of 0.01 M to 5*10-6 M. The heterogeneity index
showed a more homogenous binding site distribution.
Abstract: This article demonstrated development of
controlled release system of an NSAID drug, Diclofenac
sodium employing different ratios of Ethyl cellulose.
Diclofenac sodium and ethyl cellulose in different proportions
were processed by microencapsulation based on phase
separation technique to formulate microcapsules. The
prepared microcapsules were then compressed into tablets to
obtain controlled release oral formulations. In-vitro evaluation
was performed by dissolution test of each preparation was
conducted in 900 ml of phosphate buffer solution of pH 7.2
maintained at 37 ± 0.5 °C and stirred at 50 rpm. At predetermined
time intervals (0, 0.5, 1.0, 1.5, 2, 3, 4, 6, 8, 10, 12,
16, 20 and 24 hrs). The drug concentration in the collected
samples was determined by UV spectrophotometer at 276 nm.
The physical characteristics of diclofenac sodium
microcapsules were according to accepted range. These were
off-white, free flowing and spherical in shape. The release
profile of diclofenac sodium from microcapsules was found to
be directly proportional to the proportion of ethylcellulose and
coat thickness. The in-vitro release pattern showed that with
ratio of 1:1 and 1:2 (drug: polymer), the percentage release of
drug at first hour was 16.91 and 11.52 %, respectively as
compared to 1:3 which is only 6.87 % with in this time. The
release mechanism followed higuchi model for its release
pattern. Tablet Formulation (F2) of present study was found
comparable in release profile the marketed brand Phlogin-SR,
microcapsules showed an extended release beyond 24 h.
Further, a good correlation was found between drug release
and proportion of ethylcellulose in the microcapsules.
Microencapsulation based on coacervation found as good
technique to control release of diclofenac sodium for making
the controlled release formulations.
Abstract: one of the significant factors for improving the
accuracy of Land Surface Temperature (LST) retrieval is the correct
understanding of the directional anisotropy for thermal radiance. In
this paper, the multiple scattering effect between heterogeneous
non-isothermal surfaces is described rigorously according to the
concept of configuration factor, based on which a directional thermal
radiance model is built, and the directional radiant character for urban
canopy is analyzed. The model is applied to a simple urban canopy
with row structure to simulate the change of Directional Brightness
Temperature (DBT). The results show that the DBT is aggrandized
because of the multiple scattering effects, whereas the change range of
DBT is smoothed. The temperature difference, spatial distribution,
emissivity of the components can all lead to the change of DBT. The
“hot spot" phenomenon occurs when the proportion of high
temperature component in the vision field came to a head. On the other
hand, the “cool spot" phenomena occur when low temperature
proportion came to the head. The “spot" effect disappears only when
the proportion of every component keeps invariability. The model
built in this paper can be used for the study of directional effect on
emissivity, the LST retrieval over urban areas and the adjacency effect
of thermal remote sensing pixels.
Abstract: This paper presents the comparative study of coded
data methods for finding the benefit of concealing the natural data
which is the mercantile secret. Influential parameters of the number
of replicates (rep), treatment effects (τ) and standard deviation (σ)
against the efficiency of each transformation method are investigated.
The experimental data are generated via computer simulations under
the specified condition of the process with the completely
randomized design (CRD). Three ways of data transformation consist
of Box-Cox, arcsine and logit methods. The difference values of F
statistic between coded data and natural data (Fc-Fn) and hypothesis
testing results were determined. The experimental results indicate
that the Box-Cox results are significantly different from natural data
in cases of smaller levels of replicates and seem to be improper when
the parameter of minus lambda has been assigned. On the other hand,
arcsine and logit transformations are more robust and obviously,
provide more precise numerical results. In addition, the alternate
ways to select the lambda in the power transformation are also
offered to achieve much more appropriate outcomes.
Abstract: In this study, we developed an algorithm for detecting
seam cracks in a steel plate. Seam cracks are generated in the edge
region of a steel plate. We used the Gabor filter and an adaptive double
threshold method to detect them. To reduce the number of pseudo
defects, features based on the shape of seam cracks were used. To
evaluate the performance of the proposed algorithm, we tested 989
images with seam cracks and 9470 defect-free images. Experimental
results show that the proposed algorithm is suitable for detecting seam
cracks. However, it should be improved to increase the true positive
rate.