Abstract: Electrical Muscle Stimulation (EMS) has been
introduced and globally gained increasing attention on its usefulness.
Continuous application of EMS may lead to the increment of muscle
mass and indirectly will increase the strength. This study can be used
as an alternative to help people especially those living a sedentary
lifestyle to improve their muscle activity without having to go
through a heavy workout session. Therefore, this study intended to
investigate the effectiveness of EMS training program in 5 weeks
interventions towards male body composition. It was a quasiexperimental
design, held at the Impulse Studio Bangsar, which
examined the effects of EMS training towards skeletal muscle mass
among the subjects. Fifteen subjects (n = 15) were selected to assist
in this study. The demographic data showed that, the average age of
the subjects was 43.07 years old ± 9.90, height (173.4 cm ± 9.09) and
weight was (85.79 kg ± 18.07). Results showed that there was a
significant difference on the skeletal muscle mass (p = 0.01 < 0.05),
upper body (p = 0.01 < 0.05) and lower body (p = 0.00 < 0.05).
Therefore, the null hypothesis has been rejected in this study. As a
conclusion, the application of EMS towards body composition can
increase the muscle size and strength. This method has been proven
to be able to improve athlete strength and thus, may be implemented
in the sports science area of knowledge.
Abstract: At a global level, water stewardship, water stress and
water security are crucial factors in tourism planning and
development considerations. Challenges associated with water is of
particular concern to the Maldives as there is limited availability of
freshwater, high dependency on desalinated water, and high unit cost
associated with desalinating water. While the Maldives is promoted
as an example of sustainable tourism, a key sustainability challenge
facing tourism dependent communities is the efficient use and
management of available water resources. A water crisis event in the
capital island of Maldives highlighted how precarious water related
issues are in this tourism dependent destination. Applying
netnography, the focus of this working paper is to present community
perceptions of how government policies addressed Malé Water and
Sewerage Company (MWSC) water crisis event.
Abstract: Globally, many women are still disadvantaged when it
comes to business opportunities. Entrepreneurship development
programs, specifically designed to assist women entrepreneurs, are
assisting in solving this problem to a certain extent. The purpose of
this study is to identify the factors that motivate females to start their
own business. Females, from three different groups (2013, 2014 and
2015), who were all enrolled in a short learning program specifically
designed for women in early start-up stage or intending to start a
business, were asked what motivated them to start a business. The
results indicated that, from all three groups, the majority of the
women wanted to start a business to be independent and have
freedom and to add towards a social goal. The results further
indicated that in general, women would enter into entrepreneurship
activity due to pull factors rather than push factors.
Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: The measurement of organ radiation exposure dose is
one of the most important steps to be taken initially, for developing a
new radiopharmaceutical. In this study, the dosimetric studies of a
novel agent for SPECT-imaging of the bone metastasis, 111In-
1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic
acid (111In-DOTMP) complex, have been carried out to estimate the
dose in human organs based on the data derived from rats. The
radiolabeled complex was prepared with high radiochemical purity in
the optimal conditions. Biodistribution studies of the complex was
investigated in the male Syrian rats at selected times after injection
(2, 4, 24 and 48 h). The human absorbed dose estimation of the
complex was made based on data derived from the rats by the
radiation absorbed dose assessment resource (RADAR) method.
111In-DOTMP complex was prepared with high radiochemical purity
of >99% (ITLC). Total body effective absorbed dose for 111In-
DOTMP was 0.061 mSv/MBq. This value is comparable to the other
111In clinically used complexes. The results show that the dose with
respect to the critical organs is satisfactory within the acceptable
range for diagnostic nuclear medicine procedures. Generally, 111In-
DOTMP has interesting characteristics and can be considered as a
viable agent for SPECT-imaging of the bone metastasis in the near
future.
Abstract: The UK is leading in online retail and mobile
adoption. However, there is a dearth of information relating to mobile
apparel retail, and developing an understanding about consumer
browsing and purchase behaviour in m-retail channel would provide
apparel marketers, mobile website and app developers with the
necessary understanding of consumers’ needs. Despite the rapid
growth of mobile retail businesses, no published study has examined
shopping behaviour on fashion mobile apps and websites. A mixed method approach helped to understand why fashion
consumers prefer websites on smartphones, when diverse mobile
apps are also available. The following research methods were
employed: survey, eye-tracking experiments, observation, and
interview with retrospective think aloud. The mobile gaze tracking
device by SensoMotoric Instruments was used to understand
frustrations in navigation and other issues facing consumers in
mobile channel. This method helped to validate and compliment
other traditional user-testing approaches in order to optimize user
experience and enhance the development of mobile retail channel.
The study involved eight participants - females aged 18 to 35 years
old, who are existing mobile shoppers. The participants used the
Topshop mobile app and website on a smart phone to complete a task
according to a specified scenario leading to a purchase. The
comparative study was based on: duration and time spent at different
stages of the shopping journey, number of steps involved and product
pages visited, search approaches used, layout and visual clues, as
well as consumer perceptions and expectations. The results from the data analysis show significant differences in
consumer behaviour when using a mobile app or website on a smart
phone. Moreover, two types of problems were identified, namely
technical issues and human errors. Having a mobile app does not
guarantee success in satisfying mobile fashion consumers. The
differences in the layout and visual clues seem to influence the
overall shopping experience on a smart phone. The layout of search
results on the website was different from the mobile app. Therefore,
participants, in most cases, behaved differently on different
platforms. The number of product pages visited on the mobile app
was triple the number visited on the website due to a limited visibility
of products in the search results. Although, the data on traffic trends
held by retailers to date, including retail sector breakdowns for visits
and views, data on device splits and duration, might seem a valuable
source of information, it cannot explain why consumers visit many
product pages, stay longer on the website or mobile app, or abandon
the basket. A comprehensive list of pros and cons was developed by
highlighting issues for website and mobile app, and recommendations
provided. The findings suggest that fashion retailers need to be aware of
actual consumers’ behaviour on the mobile channel and their expectations in order to offer a seamless shopping experience. Added
to which is the challenge of retaining existing and acquiring new
customers. There seem to be differences in the way fashion
consumers search and shop on mobile, which need to be explored in
further studies.
Abstract: The present study examined how translation teachers
develop final tests as measures for checking on the quality of
students’ academic translation in Iranian context. To achieve this
goal, thirty experienced male and female translation teachers from the
four types of the universities offering the program were invited to an
in-depth 30-minute one-session semi-structured interview. The
responses provided showed how much discrepancy exists among the
Iranian translation teachers (as developers of final translation tests),
who are least informed with the current translation evaluation
methods. It was also revealed that the criteria they use for developing
such tests and scoring student translations are not theory-driven but
are highly subjective, mainly based on their personal experience and
intuition. Hence, the quality and accountability of such tests are under
serious question. The results also confirmed that the dominant
method commonly and currently practiced is the purely essay-type
format. To remedy the situation, some suggestions are in order. As
part of the solution, to improve the reliability and validity of such
tests, the present summative, product-oriented evaluation should be
accompanied with some formative, process-oriented methods of
evaluation. Training the teachers and helping them get acquainted
with modern principles of translation evaluation as well as the
existing models, and rating scales does improve the quality of
academic translation evaluation.
Abstract: The aim of this study was to determine the factor
structure and psychometric properties (i.e., reliability and convergent
validity) of the Employee Trust Scale, a newly created instrument by
the researchers. The Employee Trust Scale initially contained 82
items to measure employees’ trust toward their supervisors. A sample
of 818 (343 females, 449 males) employees were selected randomly
from public and private organization sectors in Kota Kinabalu,
Sabah, Malaysia. Their ages ranged from 19 to 67 years old with a
mean of 34.55 years old. Their average tenure with their current
employer was 11.2 years (s.d. = 7.5 years). The respondents were
asked to complete the Employee Trust Scale, as well as a managerial
trust questionnaire from Mishra. The exploratory factor analysis on
employees’ trust toward their supervisor’s extracted three factors,
labeled ‘trustworthiness’ (32 items), ‘position status’ (11 items) and
‘relationship’ (6 items) which accounted for 62.49% of the total
variance. Trustworthiness factors were re-categorized into three sub
factors: competency (11 items), benevolence (8 items) and integrity
(13 items). All factors and sub factors of the scales demonstrated
clear reliability with internal consistency of Cronbach’s Alpha above
.85. The convergent validity of the Scale was supported by an
expected pattern of correlations (positive and significant correlation)
between the score of all factors and sub factors of the scale and the
score on the managerial trust questionnaire, which measured the same
construct. The convergent validity of Employee Trust Scale was
further supported by the significant and positive inter-correlation
between the factors and sub factors of the scale. The results suggest
that the Employee Trust Scale is a reliable and valid measure.
However, further studies need to be carried out in other groups of
sample as to further validate the Scale.
Abstract: Urinary Tract Infections are considered as one of the
most common bacterial infections with an estimated annual global
incidence of 150 million. Antimicrobial drug resistance is one of the
major threats due to wide spread usage of uncontrolled antibiotics. In
this study, a total number of 9149 urine samples were collected from
R.H Patiala and processed in the Department of Microbiology G. M.
C Patiala (January 2013 to December 2013). Urine samples were
inoculated on MacConkey’s and blood agar plates and incubated at
370C for 24 hrs. The organisms were identified by colony characters,
Gram’s staining, and biochemical reactions. Antimicrobial
susceptibility of the isolates was determined against various
antimicrobial agents (Hi – Media Mumbai India) by Kirby Bauer
DISK diffusion method on Muller Hinton agar plates. Maximum patients were in the age group of 21-30 yrs followed by
31-40 yrs. Males (34%) are less prone to urinary tract infections than
females (66%). Culture was positive in 25% of the samples.
Escherichia coli was the most common isolate 60.3% followed by
Klebsiella pneumoniae 13.5%, Proteus spp. 9% and Staphylococcus
aureus 7.6%. Most of the urinary isolates were sensitive to,
carbepenems, Aztreonam, Amikacin, and Piperacillin + Tazobactum.
All the isolates showed a good sensitivity towards Nitrofurantoin
(82%). ESBL production was found to be 70.6% in Escherichia coli
and 29.4% in Klebsiella pneumonia. Susceptibility of ESBL
producers to Imipenem, Nitrofurantoin and Amikacin were found to
be 100%, 76%, and 75% respectively. Uropathogens are increasingly
showing resistance to many antibiotics making empiric management
of outpatient UTIs challenging. Ampicillin, Cotrimoxazole and
Ciprofloxacin should not be used in empiric treatment. Nitrofurantoin
could be used in lower urinary tract infection. Knowledge of
uropathogens and their antimicrobial susceptibility pattern in a
geographical region will help in appropriate and judicious antibiotic
usage in a health care setup.
Abstract: New and more powerful communications technologies
continue to emerge at a rapid pace and their uses in education are
widespread and the impact remarkable in the developing societies.
This study investigates Mobile Collaboration Learning Technique
(MCLT) on learners’ outcome among students in tertiary institutions
of developing nations (a case of Nigeria students). It examines the
significance of retention achievement scores of students taught using
mobile collaboration and conventional method. The sample consisted
of 120 students using Stratified random sampling method. Five
research questions and hypotheses were formulated, and tested at
0.05 level of significance. A student achievement test (SAT) was
made of 40 items of multiple-choice objective type, developed and
validated for data collection by professionals. The SAT was
administered to students as pre-test and post-test. The data were
analyzed using t-test statistic to test the hypotheses. The result
indicated that students taught using MCLT performed significantly
better than their counterparts using the conventional method of
instruction. Also, there was no significant difference in the post-test
performance scores of male and female students taught using MCLT.
Based on the findings, the following submissions was made that:
Mobile collaboration system be encouraged in the institutions to
boost knowledge sharing among learners, workshop and training
should be organized to train teachers on the use of this technique,
schools and government should consistently align curriculum
standard to trends of technological dictates and formulate policies
and procedures towards responsible use of MCLT.
Abstract: The authors conducted a study for the sample size of
75 HR managers from an Indian IT company through systematic
sampling method. This study identifies that the female employees are
facing lesser conflict than the male employees against their managers
within the organization. There is a positive correlation between
gender and conflict management with the superior towards the work.
There is a significant variance between age and response towards
appraisal system, succession planning and employee engagement.
The education qualification plays a major role in determining the
compensation factor for the employees working in the organization.
The study determines the impact of demographic profile on strategic
HRM practices and its challenges faced by HR managers in IT firm,
India.
Abstract: In this paper, we present a quantum statistical
mechanical formulation from our recently analytical expressions for
partial-wave transition matrix of a three-particle system. We report
the quantum reactive cross sections for three-body scattering
processes 1+(2,3)→1+(2,3) as well as recombination
1+(2,3)→1+(3,1) between one atom and a weakly-bound dimer. The
analytical expressions of three-particle transition matrices and their
corresponding cross-sections were obtained from the threedimensional
Faddeev equations subjected to the rank-two non-local
separable potentials of the generalized Yamaguchi form. The
equilibrium quantum statistical mechanical properties such partition
function and equation of state as well as non-equilibrium quantum
statistical properties such as transport cross-sections and their
corresponding transport collision integrals were formulated
analytically. This leads to obtain the transport properties, such as
viscosity and diffusion coefficient of a moderate dense gas.
Abstract: Second generation military Filipino Amerasians
comprise a formidable contemporary segment of the estimated
250,000-plus biracial Amerasians in the Philippines today. Overall,
they are a stigmatized and socioeconomically marginalized diaspora;
historically, they were abandoned or estranged by U.S. military
personnel fathers assigned during the century-long Colonial, Post-
World War II and Cold War Era of permanent military basing (1898-
1992). Indeed, U.S. military personnel are assigned in smaller
numbers in the Philippines today. This inquiry is an outgrowth of two
recent small sample studies. The first surfaced the impact of the U.S.
military prostitution system on formation of the ‘Derivative
Amerasian Family Construct’ on first generation Amerasians; a
second, qualitative case study suggested the continued effect of the
prostitution systems' destructive impetuous on second generation
Amerasians. The intent of this current qualitative, multiple-case study
was to actively seek out second generation sex industry toilers. The
purpose was to focus further on this human phenomenon in the postbasing
and post-military prostitution system eras. As background, the
former military prostitution apparatus has transformed into a modern
dynamic of rampant sex tourism and prostitution nationwide. This is
characterized by hotel and resorts offering unrestricted carnal access,
urban and provincial brothels (casas), discos, bars and pickup clubs,
massage parlors, local barrio karaoke bars and street prostitution. A
small case study sample (N = 4) of female and male second
generation Amerasians were selected. Sample formation employed a
non-probability ‘snowball’ technique drawing respondents from the
notorious Angeles, Metro Manila, Olongapo City ‘AMO Amerasian
Triangle’ where most former U.S. military installations were sited
and modern sex tourism thrives. A six-month study and analysis of
in-depth interviews of female and male sex laborers, their families
and peers revealed a litany of disturbing, and troublesome
experiences. Results showed profiles of debilitating human poverty,
history of family disorganization, stigmatization, social
marginalization and the ghost of the military prostitution system and
its harmful legacy on Amerasian family units. Emerging were testimonials of wayward young people ensnared in a maelstrom of
deep economic deprivation, familial dysfunction, psychological
desperation and societal indifference. The paper recommends that
more study is needed and implications of unstudied psychosocial and
socioeconomic experiences of distressed younger generations of
military Amerasians require specific research. Heretofore apathetic or
disengaged U.S. institutions need to confront the issue and formulate
activist and solution-oriented social welfare, human services and
immigration easement policies and alternatives. These institutions
specifically include academic and social science research agencies,
corporate foundations, the U.S. Congress, and Departments of State,
Defense and Health and Human Services, and Homeland Security
(i.e. Citizen and Immigration Services) It is them who continue to
endorse a laissez-faire policy of non-involvement over the entire
Filipino Amerasian question. Such apathy, the paper concludes,
relegates this consequential but neglected blood progeny to the status
of humiliating destitution and exploitation. Amerasians; thus, remain
entrapped in their former colonial, and neo-colonial habitat.
Ironically, they are unwitting victims of a U.S. American homeland
that fancies itself geo-politically as a strong and strategic military
treaty ally of the Philippines in the Western Pacific.
Abstract: This paper explores and provides substantiated
evidence on the usage patterns of Information and Communication
Technologies (ICTs) by female users at Vhembe District in Limpopo-
Province, South Africa. The study presents a comprehensive picture
on the usage of ICTs from female users’ perspective. The
significance of this study stems from the need to assess the role,
relevance and usage patterns of ICTs such as smartphones,
computers, laptops, and iPods, the internet and social networking
sites among females following the developments of new media
technologies in society. The objective of the study is to investigate
the usability and accessibility of ICTs to empower female users in
South Africa. The study used quantitative and qualitative research
methods to determine the major ideas, perceptions and usage patterns
of ICTs by users. Data collection involved the use of structured selfadministered
questionnaire from two groups of respondents who
participated in this study. Thus, (n=50) female students at the
University of Venda provided their ideas and perceptions about the
usefulness and usage patterns of ICTs such as smartphones, the
Internet and computers at the university level, whereas, the second
group were (n=50) learners from Makhado Comprehensive School
who provided their perceptions and ideas about the use of ICTs at the
high school level. The researcher also noted that the findings of the
study were useful as a guideline and model for ICT intervention that
could work as an empowerment to women in South Africa. It was
observed that the central purpose of ICTs among female users was to
search for information regarding assignment writing, conducting
research, dating, exchanging ideas and networking with friends and
relatives. This was demonstrated by a high number of females who
used ICTs for e-learning (62%) and social purposes (85%).
Therefore, the study revealed that most females used ICTs for social
purposes and accessing the internet rather than for entertainment, a
gesture that provides an opportune space to empower rural women in
South Africa.
Abstract: The present study aimed to determine the
effectiveness of Metaphor therapy on depression among female
students. The sample included 60 female students with depression
symptoms selected by simple sampling and randomly divided into
two equal groups (experimental and control groups). Beck
Depression Inventory was used to measure the variables. This was an
experimental study with a pre-test/post-test design with control
group. Eight metaphor therapy sessions were held for the
experimental group. A post-test was administered to both groups.
Data were analyzed using multivariate analysis of covariance
(MANCOVA). Results showed that the Metaphor therapy decreased
depression in the experimental group compared to the control group.
Abstract: The present research investigated whether gender
differences affect performance in a simple math quiz in statistics
course. Participants of this study comprised a sample of 567 statistics
students in two different universities in Lebanon. Data were collected
through a simple math quiz. Analysis of quantitative data indicated
that there wasn’t a significant difference in math performance
between males and females. The results suggest that improvements in
student performance may depend on improved mastery of basic
algebra especially for females. The implications of these findings and
further recommendations were discussed.
Abstract: The current paper presents the results of a conducted
case study. During the past few years the number of children
diagnosed with Learning Difficulties has drastically augmented and
especially the cases of ADHD (Attention Deficit Hyperactivity
Disorder). One of the core characteristics of ADHD is a deficit in
working memory functions. The review of the literature indicates a
plethora of educational software that aim at training and enhancing
the working memory. Nevertheless, in the current paper, the
possibility of using for the same purpose free, online games will be
explored. Another issue of interest is the potential effect of the
working memory training to the core symptoms of ADHD. In order
to explore the abovementioned research questions, three digital tests
are employed, all of which are developed on the E-slate platform by
the author, in order to check the levels of ADHD’s symptoms and to
be used as diagnostic tools, both in the beginning and in the end of
the case study. The tools used during the main intervention of the
research are free online games for the training of working memory.
The research and the data analysis focus on the following axes: a) the
presence and the possible change in two of the core symptoms of
ADHD, attention and impulsivity and b) a possible change in the
general cognitive abilities of the individual. The case study was
conducted with the participation of a thirteen year-old, female
student, diagnosed with ADHD, during after-school hours. The
results of the study indicate positive changes both in the levels of
attention and impulsivity. Therefore, we conclude that the training of
working memory through the use of free, online games has a positive
impact on the characteristics of ADHD. Finally, concerning the
second research question, the change in general cognitive abilities, no
significant changes were noted.
Abstract: The Multiple Intelligences theory characterizes human
intelligence as a multifaceted entity that exists in all human beings
with varying degrees. The most important contribution of this theory
to the field of English Language Teaching (ELT) is its role in
identifying individual differences and designing more learnercentered
programs. The present study aims at investigating the
relationship between different elements of multiple intelligence and
grammar scores. To this end, 63 female Iranian EFL learner selected
from among intermediate students participated in the study. The
instruments employed were a Nelson English language test, Michigan
Grammar Test, and Teele Inventory for Multiple Intelligences
(TIMI). The results of Pearson Product-Moment Correlation revealed
a significant positive correlation between grammatical accuracy and
linguistic as well as interpersonal intelligence. The results of
Stepwise Multiple Regression indicated that linguistic intelligence
contributed to the prediction of grammatical accuracy.
Abstract: The global demand for long-tailed macaques for
medical experimentation has continued to increase. Fulfillment of
Indonesian export demands has been mostly from natural habitats,
based on a harvesting quota. This quota has been determined
according to the total catch for a given year, and not based on
consideration of any demographic parameters or physical
environmental factors with regard to the animal; hence threatening
the sustainability of the various populations. It is therefore necessary
to formulate a method for calculating a sustainable harvesting quota,
based on population parameters in natural habitats. Considering the
possibility of variations in habitat characteristics and population
parameters, a time series observation of demographic and
physical/biotic parameters, in various habitats, was performed on 13
groups of long-tailed macaques, distributed throughout the West
Java, Lampung and Yogyakarta areas of Indonesia. These provinces
were selected for comparison of the influence of human/tourism
activities. Data on population parameters that was collected included
data on life expectancy according to age class, numbers of
individuals by sex and age class, and ‘ratio of infants to reproductive
females’. The estimation of population growth was based on a
population dynamic growth model: the Leslie matrix. The harvesting
quota was calculated as being the difference between the actual
population size and the MVP (minimum viable population) for each
sex and age class. Observation indicated that there were variations within group size
(24–106 individuals), gender (sex) ratio (1:1 to 1:1.3), life expectancy
value (0.30 to 0.93), and ‘ratio of infants to reproductive females’
(0.23 to 1.56). Results of subsequent calculations showed that
sustainable harvesting quotas for each studied group of long-tailed
macaques, ranged from 29 to 110 individuals. An estimation model
of the MVP for each age class was formulated as Log Y = 0.315 +
0.884 Log Ni (number of individual on ith age class). This study also
found that life expectancy for the juvenile age class was affected by
the humidity under tree stands, and dietary plants’ density at sapling,
pole and tree stages (equation: Y=2.296 – 1.535 RH + 0.002 Kpcg –
0.002 Ktg – 0.001 Kphn, R2 = 89.6% with a significance value of
0.001). By contrast, for the sub-adult-adult age class, life expectancy
was significantly affected by slope (equation: Y=0.377 = 0.012 Kml,
R2 = 50.4%, with significance level of 0.007). The infant-toreproductive-
female ratio was affected by humidity under tree stands,
and dietary plant density at sapling and pole stages (equation: Y = -
1.432 + 2.172 RH – 0.004 Kpcg + 0.003 Ktg, R2 = 82.0% with
significance level of 0.001). This research confirmed the importance
of population parameters in determining the minimum viable
population, and that MVP varied according to habitat characteristics
(especially food availability). It would be difficult therefore, to
formulate a general mathematical equation model for determining a
harvesting quota for the species as a whole.
Abstract: Effects of nicotine on pre-partum body weight and
preimplantation embryonic development has been reported
previously. Present study was conducted to determine the effects of
annatto (Bixa orellana)-derived delta-tocotrienol (TCT) (with
presence of 10% gamma-TCT isomer) on the nicotine-induced
reduction in body weight and 8-cell embryonic growth in mice.
Twenty-four 6-8 weeks old (23-25g) female balb/c mice were
randomly divided into four groups (G1-G4; n=6). Those groups were
subjected to the following treatments for 7 consecutive days: G1
(control) were gavaged with 0.1 ml tocopherol stripped corn oil. G2
was subcutaneously (s.c.) injected with 3 mg/kg/day of nicotine. G3
received concurrent treatment of nicotine (3 mg/kg/day) and 60
mg/kg/day of δ-TCT mixture (contains 90% delta & 10% gamma
isomers) and G4 was given 60 mg/kg/day of δ-TCT mixture alone.
Body weights were recorded daily during the treatment. On Day 8,
females were superovulated with 5 IU Pregnant Mare’s Serum
Gonadotropin (PMSG) for 48 hours followed with 5 IU human
Chorionic Gonadotropin (hCG) before mated with males at the ratio
of 1:1. Females were sacrificed by cervical dislocation for embryo
collection 48 hours post-coitum. Collected embryos were cultured in
vitro. Results showed that throughout Day 1 to Day 7, the body
weight of nicotine treated group (G2) was significantly lower
(p