Abstract: Lateral torsional buckling is a global buckling mode
which should be considered in design of slender structural members
under flexure about their strong axis. It is possible to compute the
load which causes lateral torsional buckling of a beam by finite
element analysis, however, closed form equations are needed in
engineering practice for calculation ease which can be obtained by
using energy method. In lateral torsional buckling applications of
energy method, a proper function for the critical lateral torsional
buckling mode should be chosen which can be thought as the
variation of twisting angle along the buckled beam. Accuracy of the
results depends on how close is the chosen function to the exact
mode. Since critical lateral torsional buckling mode of the cantilever
I-beams varies due to material properties, section properties and
loading case, the hardest step is to determine a proper mode function
in application of energy method. This paper presents an approximate function for critical lateral
torsional buckling mode of doubly symmetric cantilever I-beams.
Coefficient matrices are calculated for concentrated load at free end,
uniformly distributed load and constant moment along the beam
cases. Critical lateral torsional buckling modes obtained by presented
function and exact solutions are compared. It is found that the modes
obtained by presented function coincide with differential equation
solutions for considered loading cases.
Abstract: Cancer is still one of the serious diseases threatening
the lives of human beings. How to have an early diagnosis and
effective treatment for tumors is a very important issue. The animal
carcinoma model can provide a simulation tool for the studies of
pathogenesis, biological characteristics, and therapeutic effects.
Recently, drug delivery systems have been rapidly developed to
effectively improve the therapeutic effects. Liposome plays an
increasingly important role in clinical diagnosis and therapy for
delivering a pharmaceutic or contrast agent to the targeted sites.
Liposome can be absorbed and excreted by the human body, and is
well known that no harm to the human body. This study aimed to
compare the therapeutic effects between encapsulated (doxorubicin
liposomal, Lipodox) and un-encapsulated (doxorubicin, Dox)
anti-tumor drugs using magnetic resonance imaging (MRI).
Twenty-four New Zealand rabbits implanted with VX2 carcinoma at
left thighs were classified into three groups: control group (untreated),
Dox-treated group, and LipoDox-treated group, 8 rabbits for each
group. MRI scans were performed three days after tumor implantation.
A 1.5T GE Signa HDxt whole body MRI scanner with a high
resolution knee coil was used in this study. After a 3-plane localizer
scan was performed, three-dimensional (3D) fast spin echo (FSE)
T2-weighted Images (T2WI) was used for tumor volumetric
quantification. Afterwards, two-dimensional (2D) spoiled gradient
recalled echo (SPGR) dynamic contrast-enhanced (DCE) MRI was
used for tumor perfusion evaluation. DCE-MRI was designed to
acquire four baseline images, followed by contrast agent Gd-DOTA
injection through the ear vein of rabbit. A series of 32 images were
acquired to observe the signals change over time in the tumor and
muscle. The MRI scanning was scheduled on a weekly basis for a
period of four weeks to observe the tumor progression longitudinally.
The Dox and LipoDox treatments were prescribed 3 times in the first
week immediately after the first MRI scan; i.e. 3 days after VX2 tumor
implantation. ImageJ was used to quantitate tumor volume and time
course signal enhancement on DCE images. The changes of tumor size
showed that the growth of VX2 tumors was effectively inhibited for
both LipoDox-treated and Dox-treated groups. Furthermore, the tumor
volume of LipoDox-treated group was significantly lower than that of
Dox-treated group, which implies that LipoDox has better therapeutic effect than Dox. The signal intensity of LipoDox-treated group is
significantly lower than that of the other two groups, which implies
that targeted therapeutic drug remained in the tumor tissue. This study
provides a radiation-free and non-invasive MRI method for
therapeutic monitoring of targeted liposome on an animal tumor
model.
Abstract: In this paper a very simple and effective user
administration view of computing clusters systems is implemented in
order of friendly provide the configuration and monitoring of
distributed application executions. The user view, the administrator
view, and an internal control module create an illusionary
management environment for better system usability. The
architecture, properties, performance, and the comparison with others
software for cluster management are briefly commented.
Abstract: The aim of this study is to empirically investigate the
mediating impact of export performance (EP) between technological
advancement capabilities and business performance (BP) of
Malaysian manufacturing micro, small and medium sized enterprises
(MSME’s). Firm’s technological advancement resources are
hypothesized as a platform to enhance both exports and BP of
manufacturing MSMEs in Malaysia. This study is twofold, primary it
has investigated that technological advancement capabilities helps to
appreciates main performance measures noted in terms of EP and
Secondly, it investigates that how efficiently and effectively
technological advancement capabilities can contribute in overall
Malaysian MSME’s BP. Smart PLS-3 statistical software is used to
know the association between technological advancement
capabilities, MSME’s EP and BP. In this study, the data was
composed from Malaysian manufacturing MSME’s in east coast
industrial zones known as the manufacturing hub of MSMEs. Seven
hundred and fifty (750) questionnaires were distributed, but only 148
usable questionnaires are returned. The finding of this study indicated
that technological advancement capabilities helps to strengthen the
export in term of time and cost efficient and it plays a significant role
in appreciating their BP. This study is helpful for small and medium
enterprise owners who intend to expand their business overseas and
though smart technological advancement resources they can achieve
their business competitiveness and excellence both at local and
international markets.
Abstract: An early diagnosis of bone metastasis is very
important for making a right decision on a subsequent therapy. One
of the most important steps to be taken initially, for developing a new
radiopharmaceutical is the measurement of organ radiation exposure
dose. In this study, the dosimetric studies of a novel agent for
SPECT-imaging of the bone metastasis, 111In-(4-
{[(bis(phosphonomethyl))carbamoyl]methyl}7,10bis(carboxymethyl)
-1,4,7,10-tetraazacyclododec-1-yl) acetic acid (111In-BPAMD)
complex, have been carried out to estimate the dose in human organs
based on the data derived from mice. The radiolabeled complex was
prepared with high radiochemical purity in the optimal conditions.
Biodistribution studies of the complex was investigated in the male
Syrian mice at the selected times after injection (2, 4, 24 and 48 h).
The human absorbed dose estimation of the complex was made based
on data derived from the mice by the radiation absorbed dose
assessment resource (RADAR) method. 111In-BPAMD complex was prepared with high radiochemical
purity >95% (ITLC) and specific activities of 2.85 TBq/mmol. Total
body effective absorbed dose for 111In-BPAMD was 0.205
mSv/MBq. This value is comparable to the other 111In clinically used
complexes. The results show that the dose with respect to the critical
organs is satisfactory within the acceptable range for diagnostic
nuclear medicine procedures. Generally, 111In-BPAMD has
interesting characteristics and it can be considered as a viable agent
for SPECT-imaging of the bone metastasis in the near future.
Abstract: In this article, we used the residual correction method
to deal with transient thermoelastic problems with a hollow spherical
region when the continuum medium possesses spherically isotropic
thermoelastic properties. Based on linear thermoelastic theory, the
equations of hyperbolic heat conduction and thermoelastic motion
were combined to establish the thermoelastic dynamic model with
consideration of the deformation acceleration effect and non-Fourier
effect under the condition of transient thermal shock. The approximate
solutions of temperature and displacement distributions are obtained
using the residual correction method based on the maximum principle
in combination with the finite difference method, making it easier and
faster to obtain upper and lower approximations of exact solutions.
The proposed method is found to be an effective numerical method
with satisfactory accuracy. Moreover, the result shows that the effect
of transient thermal shock induced by deformation acceleration is
enhanced by non-Fourier heat conduction with increased peak stress.
The influence on the stress increases with the thermal relaxation time.
Abstract: A clay soil classified as A-7-6 and CH soil according
to AASHTO and unified soil classification system respectively, was
stabilized using A-3 soil (AASHTO soil classification system). The
clay soil was replaced with 0%, 10%, 20%, to 100% A-3 soil,
compacted at both British Standard Light (BSL) and British Standard
Heavy (BSH) compaction energy levels and using Unconfined
Compressive Strength (UCS) as evaluation criteria. The Maximum
Dry Density (MDD) of the treated soils at both the BSL and BSH
compaction energy levels showed increase from 0% to 40% A-3 soil
replacement after which the values reduced to 100% replacement.
The trend of the Optimum Moisture Content (OMC) with varied A-3
soil replacement was similar to that of MDD but in a reversed order.
The OMC reduced from 0% to 40% A-3 soil replacement after which
the values increased to 100% replacement. This trend was attributed
to the observed reduction in void ratio from 0% to 40% replacement
after which the void ratio increased to 100% replacement. The
maximum UCS for the soil at varied A-3 soil replacement increased
from 272 and 770 kN/m2 for BSL and BSH compaction energy level
at 0% replacement to 295 and 795 kN/m2 for BSL and BSH
compaction energy level respectively at 10% replacement after which
the values reduced to 22 and 60 kN/m2 for BSL and BSH compaction
energy level respectively at 70% replacement. Beyond 70%
replacement, the mixtures could not be moulded for UCS test.
Abstract: One of the challenges that higher education faces is to
find how to approach the sustainability in an inclusive way to the
student within all the different academic areas, how to move the
sustainable development from the abstract field to the operational
field. This research comes from the ecoliteracy and the pedagogical
praxis as tools for rebuilding the teaching processes inside of
universities. The purpose is to determine and describe which are the
factors involved in the process of learning particularly in the
Greenhouse-School Siembra UV. In the Greenhouse-School Siembra UV, of the University of
Veracruz, are cultivated vegetables, medicinal plants and small
cornfields under the usage of eco-technologies such as hydroponics,
Wickingbed and Hugelkultur, which main purpose is the saving of
space, labor and natural resources, as well as function as agricultural
production alternatives in the urban and periurban zones. The sample was formed with students from different academic
areas and who are actively involved in the greenhouse, as well as
institutes from the University of Veracruz and governmental and nongovernmental
departments. This project comes from a pedagogic praxis approach, from filling
the needs that the different professional profiles of the university
students have. All this with the purpose of generate a pragmatic
dialogue with the sustainability. It also comes from the necessity to
understand the factors that intervene in the students’ praxis. In this
manner is how the students are the fundamental unit in the sphere of
sustainability. As a result, it is observed that those University of Veracruz
students who are involved in the Greenhouse-school, Siembra UV,
have enriched in different levels the sense of urban and periurban
agriculture because of the diverse academic approaches they have
and the interaction between them. It is concluded that the ecotechnologies
act as fundamental tools for ecoliteracy in society,
where it is strengthen the nutritional and food security from a
sustainable development approach.
Abstract: An unrecorded experiment of use of the smartphone
as a tool for practical classes of histology is presented in this paper.
Behavior and learning of students of science courses at the University
were analyzed and compared as well as the mode of teaching of this
discipline and the appreciation of the students, using either digital
photographs taken by phone or drawings for record microscopic
observations, analyze and interpret histological sections of human or
animal tissues.
Abstract: In this paper, we describe an application for face
recognition. Many studies have used local descriptors to characterize
a face, the performance of these local descriptors remain low by
global descriptors (working on the entire image). The application of
local descriptors (cutting image into blocks) must be able to store
both the advantages of global and local methods in the Discrete
Cosine Transform (DCT) domain. This system uses neural network
techniques. The letter method provides a good compromise between
the two approaches in terms of simplifying of calculation and
classifying performance. Finally, we compare our results with those
obtained from other local and global conventional approaches.
Abstract: The traditional rhythms of the West African country
of Guinea have played a centuries-long role in defining the different
people groups that make up the country. Throughout their history,
before and since colonization by the French, the different ethnicities
have used their traditional music as a distinct part of their historical
identities. That is starting to change. Guinea is an impoverished
nation created in the early twentieth-century with little regard for the
history and cultures of the people who were included. The traditional
rhythms of the different people groups and their heritages have
remained. Fifteen individual traditional Guinean rhythms were
chosen to represent popular rhythms from the four geographical
regions of Guinea. Each rhythm was traced back to its native village
and video recorded on-site by as many different local performing
groups as could be located. The cyclical patterns rhythms were
transcribed via a circular, spatial design and then copied into a box
notation system where sounds happening at the same time could be
studied. These rhythms were analyzed for their consistency-overperformance
in a Fundamental Rhythm Pattern analysis so rhythms
could be compared for how they are changing through different
performances. The analysis showed that the traditional rhythm
performances of the Middle and Forest Guinea regions were the most
cohesive and showed the least evidence of change between
performances. The role of music in each of these regions is both
limited and focused. The Coastal and High Guinea regions have
much in common historically through their ethnic history and
modern-day trade connections, but the rhythm performances seem to
be less consistent and demonstrate more changes in how they are
performed today. In each of these regions the role and usage of music
is much freer and wide-spread. In spite of advances being made as a
country, different ethnic groups still frequently only respond and
participate (dance and sing) to the music of their native ethnicity.
There is some evidence that this self-imposed musical barrier is
beginning to change and evolve, partially through the development of
better roads, more access to electricity and technology, the nationwide
Ebola health crisis, and a growing self-identification as a
unified nation.
Abstract: In this paper, we present an application of Riemannian
geometry for processing non-Euclidean image data. We consider the
image as residing in a Riemannian manifold, for developing a new
method to brain edge detection and brain extraction. Automating this
process is a challenge due to the high diversity in appearance brain
tissue, among different patients and sequences. The main contribution, in this paper, is the use of an edge-based
anisotropic diffusion tensor for the segmentation task by integrating
both image edge geometry and Riemannian manifold (geodesic,
metric tensor) to regularize the convergence contour and extract
complex anatomical structures. We check the accuracy of the
segmentation results on simulated brain MRI scans of single
T1-weighted, T2-weighted and Proton Density sequences. We
validate our approach using two different databases: BrainWeb
database, and MRI Multiple sclerosis Database (MRI MS DB). We
have compared, qualitatively and quantitatively, our approach with
the well-known brain extraction algorithms. We show that using
a Riemannian manifolds to medical image analysis improves the
efficient results to brain extraction, in real time, outperforming the
results of the standard techniques.
Abstract: The article deals with the readiness of military
professionals for challenging situations. It discusses higher
requirements on the psychical endurance of military professionals
arising from the specific nature of the military occupation, which is
typical for being very difficult to maintain regularity, which is in
accordance with the hygiene of work alternated by relaxation. The
soldier must be able to serve in the long term and constantly intense
performance that goes beyond human tolerance to stress situations. A
challenging situation is always associated with overcoming
difficulties, obstacles and complicated circumstances or using
unusual methods, ways and means to achieve the desired (expected)
objectives, performing a given task or satisfying an important need.
This paper describes the categories of challenging situations, their
classification and characteristics. Attention is also paid to the
formation of personality in challenging situations, coping with stress
in challenging situations, Phases of solutions of stressful situations,
resistance to challenging life situations and its factors. Finally, the
article is focused on increasing the readiness of military professionals
for challenging situations.
Abstract: The use of wireless technology in industrial networks
has gained vast attraction in recent years. In this paper, we have
thoroughly analyzed the effect of contention window (CW) size on
the performance of IEEE 802.11-based industrial wireless networks
(IWN), from delay and reliability perspective. Results show that the
default values of CWmin, CWmax, and retry limit (RL) are far from
the optimum performance due to the industrial application
characteristics, including short packet and noisy environment. In this
paper, an adaptive CW algorithm (payload-dependent) has been
proposed to minimize the average delay. Finally a simple, but
effective CW and RL setting has been proposed for industrial
applications which outperforms the minimum-average-delay solution
from maximum delay and jitter perspective, at the cost of a little
higher average delay. Simulation results show an improvement of up
to 20%, 25%, and 30% in average delay, maximum delay and jitter
respectively.
Abstract: This contribution is focused on the methodology for
identifying levels of quality and improving quality through new
logistics model in railway transport. It is oriented on the application
of dynamic quality models, which represent an innovative method of
evaluation quality services. Through this conception, time factor,
expected, and perceived quality in each moment of the transportation
process within logistics chain can be taken into account. Various
models describe the improvement of the quality which emphases the
time factor throughout the whole transportation logistics chain.
Quality of services in railway transport can be determined by the
existing level of service quality, by detecting the causes of
dissatisfaction employees but also customers, to uncover strengths
and weaknesses. This new logistics model is able to recognize critical
processes in logistic chain. It includes service quality rating that must
respect its specific properties, which are unrepeatability,
impalpability, their use right at the time they are provided and
particularly changeability, which is significant factor in the
conditions of rail transport as well. These peculiarities influence the
quality of service regarding the constantly increasing requirements
and that result in new ways of finding progressive attitudes towards
the service quality rating.
Abstract: This article describes the results of research focused
on quality of railway freight transport services. Improvement of these
services has a crucial importance in customer considering on the
future use of railway transport. Processes filling the customer
demands and output quality assessment were defined as a part of the
research. In this contribution is introduced the map of quality
planning and the algorithm of applied methodology. It characterizes a
model which takes into account characters of transportation with
linking a perception services quality in ordinary and extraordinary
operation. Despite the fact that rail freight transport has its solid
position in the transport market, lots of carriers worldwide have been
experiencing a stagnation for a couple of years. Therefore, specific
results of the research have a significant importance and belong to
numerous initiatives aimed to develop and support railway transport
not only by creating a single railway area or reducing noise but also
by promoting railway services. This contribution is focused also on
the application of dynamic quality models which represent an
innovative method of evaluation quality services. Through this
conception, time factor, expected, and perceived quality in each
moment of the transportation process can be taken into account.
Abstract: Abstract—[Tris (1,10-phenanthroline) lanthanum(III)]
trithiocyanate is a new compound that has shown high ability for
stopping the synthesis of DNA and also acting as a photosensitizer.
Nowadays, the radiation dose assessment resource (RADAR) method
is known as the most common method for absorbed dose calculation.
177Lu was produced by (n, gamma) reaction in a research reactor.
177Lu-PL3 was prepared in the optimized condition. The
radiochemical yield was checked by ITLC method. The
biodistribution of the complex was investigated by intravenously
injection to wild-type rats via their tail veins. In this study, the
absorbed dose of 177Lu-PL3 to human organs was estimated by
RADAR method. 177Lu was prepared with a specific activity of 2.6-3
GBq.mg-1 and radionuclide purity of 99.98 %. Final preparation of
the radiolabelled complex showed high radiochemical purity of >
99%. The results show that liver and spleen have received the highest
absorbed dose of 1.051 and 0.441 mSv/MBq, respectively. The
absorbed dose values for these two dose-limiting tissues suggest
more biological studies special in tumor-bearing animals.
Abstract: The measurement of organ radiation exposure dose is
one of the most important steps to be taken initially, for developing a
new radiopharmaceutical. In this study, the dosimetric studies of a
novel agent for SPECT-imaging of the bone metastasis, 111In-
1,4,7,10-tetraazacyclododecane-1,4,7,10 tetraethylene phosphonic
acid (111In-DOTMP) complex, have been carried out to estimate the
dose in human organs based on the data derived from rats. The
radiolabeled complex was prepared with high radiochemical purity in
the optimal conditions. Biodistribution studies of the complex was
investigated in the male Syrian rats at selected times after injection
(2, 4, 24 and 48 h). The human absorbed dose estimation of the
complex was made based on data derived from the rats by the
radiation absorbed dose assessment resource (RADAR) method.
111In-DOTMP complex was prepared with high radiochemical purity
of >99% (ITLC). Total body effective absorbed dose for 111In-
DOTMP was 0.061 mSv/MBq. This value is comparable to the other
111In clinically used complexes. The results show that the dose with
respect to the critical organs is satisfactory within the acceptable
range for diagnostic nuclear medicine procedures. Generally, 111In-
DOTMP has interesting characteristics and can be considered as a
viable agent for SPECT-imaging of the bone metastasis in the near
future.
Abstract: The aim of the study is to compare behavioral and
EEG reactions in Turkic-speaking inhabitants of Siberia (Tuvinians
and Yakuts) and Russians during the recognition of syntax errors in
native and foreign languages. Sixty-three healthy aboriginals of the
Tyva Republic, 29 inhabitants of the Sakha (Yakutia) Republic, and
55 Russians from Novosibirsk participated in the study. EEG were
recorded during execution of error-recognition task in Russian and
English language (in all participants) and in native languages
(Tuvinian or Yakut Turkic-speaking inhabitants). Reaction time (RT)
and quality of task execution were chosen as behavioral measures.
Amplitude and cortical distribution of P300 and P600 peaks of ERP
were used as a measure of speech-related brain activity. In Tuvinians,
there were no differences in the P300 and P600 amplitudes as well as
in cortical topology for Russian and Tuvinian languages, but there
was a difference for English. In Yakuts, the P300 and P600
amplitudes and topology of ERP for Russian language were the same
as Russians had for native language. In Yakuts, brain reactions during
Yakut and English language comprehension had no difference, while
the Russian language comprehension was differed from both Yakut
and English. We found out that the Tuvinians recognized both Russian and
Tuvinian as native languages, and English as a foreign language. The
Yakuts recognized both English and Yakut as foreign languages, but
Russian as a native language. According to the inquirer, both
Tuvinians and Yakuts use the national language as a spoken
language, whereas they do not use it for writing. It can well be a
reason that Yakuts perceive the Yakut writing language as a foreign
language while writing Russian as their native.
Abstract: This paper expands on the role of the professor by detailing the origins of the profession, adding some of the unique contributions of North American universities as well as some of the best practice recommendations to the unique tripartite role of the professor. It describes current challenges to the profession including the ever-controversial student rating of professors. It continues with the significance of empowerment to the role of the professor. It concludes with a predictive prescription for the future of the professoriate and the role of the university-level educational administrator toward that end.