Abstract: Titania slag is a high quality raw material containing titanium in the subsequent process of titanium pigment. The effects of cooling approaches of granulating, water cooling, and air cooling on chemical, phases, and acidolysis of Panzhihua titania slag were investigated. Compared to the original slag which was prepared by the conventional processing route, the results show that the titania slag undergoes oxidation of Ti3+during different cooling ways. The Ti2O3 content is 17.50% in the original slag, but it is 16.55% and 16.84% in water cooled and air-cooled slag, respectively. Especially, the Ti2O3 content in granulated slag is decreased about 27.6%. The content of Fe2O3 in granulated slag is approximately 2.86% also obviously higher than water (