Abstract: This paper presents a novel method for prediction of
the mechanical behavior of proximal femur using the general
framework of the quantitative computed tomography (QCT)-based
finite element Analysis (FEA). A systematic imaging and modeling
procedure was developed for reliable correspondence between the
QCT-based FEA and the in-vitro mechanical testing. A speciallydesigned
holding frame was used to define and maintain a unique
geometrical reference system during the analysis and testing. The
QCT images were directly converted into voxel-based 3D finite
element models for linear and nonlinear analyses. The equivalent
plastic strain and the strain energy density measures were used to
identify the critical elements and predict the failure patterns. The
samples were destructively tested using a specially-designed gripping
fixture (with five degrees of freedom) mounted within a universal
mechanical testing machine. Very good agreements were found
between the experimental and the predicted failure patterns and the
associated load levels.