Abstract: Diabetes is one of the high prevalence diseases
worldwide with increased number of complications, with retinopathy
as one of the most common one. This paper describes how data
mining and case-based reasoning were integrated to predict
retinopathy prevalence among diabetes patients in Malaysia. The
knowledge base required was built after literature reviews and
interviews with medical experts. A total of 140 diabetes patients- data
were used to train the prediction system. A voting mechanism selects
the best prediction results from the two techniques used. It has been
successfully proven that both data mining and case-based reasoning
can be used for retinopathy prediction with an improved accuracy of
85%.