Abstract: Certain sciences such as physics, chemistry or biology,
have a strong computational aspect and use computing infrastructures
to advance their scientific goals. Often, high performance and/or high
throughput computing infrastructures such as clusters and computational
Grids are applied to satisfy computational needs. In addition,
these sciences are sometimes characterised by scientific collaborations
requiring resource sharing which is typically provided by Grid
approaches. In this article, I discuss Grid computing approaches in
High Energy Physics as well as in bioinformatics and highlight some
of my experience in both scientific domains.