Abstract: The physical methods for RNA secondary structure prediction are time consuming and expensive, thus methods for computational prediction will be a proper alternative. Various algorithms have been used for RNA structure prediction including dynamic programming and metaheuristic algorithms. Musician's behaviorinspired harmony search is a recently developed metaheuristic algorithm which has been successful in a wide variety of complex optimization problems. This paper proposes a harmony search algorithm (HSRNAFold) to find RNA secondary structure with minimum free energy and similar to the native structure. HSRNAFold is compared with dynamic programming benchmark mfold and metaheuristic algorithms (RnaPredict, SetPSO and HelixPSO). The results showed that HSRNAFold is comparable to mfold and better than metaheuristics in finding the minimum free energies and the number of correct base pairs.
Abstract: Predictions of flow and heat transfer characteristics and shape optimization in internally finned circular tubes have been performed on three-dimensional periodically fully developed turbulent flow and thermal fields. For a trapezoidal fin profile, the effects of fin height h, upper fin widths d1, lower fin widths d2, and helix angle of fin ? on transport phenomena are investigated for the condition of fin number of N = 30. The CFD and mathematical optimization technique are coupled in order to optimize the shape of internally finned tube. The optimal solutions of the design variables (i.e., upper and lower fin widths, fin height and helix angle) are numerically obtained by minimizing the pressure loss and maximizing the heat transfer rate, simultaneously, for the limiting conditions of d1 = 0.5~1.5 mm, d2 = 0.5~1.5 mm, h= 0.5~1.5mm, ? = 10~30 degrees. The fully developed flow and thermal fields are predicted using the finite volume method and the optimization is carried out by means of the multi-objective genetic algorithm that is widely used in the constrained nonlinear optimization problem.
Abstract: Dispersions of casein micelles (CM) were studied at a
constant protein concentration of 5 wt % in high NaCl environment
ranging from 0% to 12% by Dynamic light scattering (DLS) and
Fourier Transform Infrared (FTIR). The rehydration profiles obtained
were interpreted in term of wetting, swelling and dispersion stages by
using a turbidity method. Two behaviours were observed depending
on the salt concentration. The first behaviour (low salt concentration)
presents a typical rehydration profile with a significant change
between 3 and 6% NaCl indicating quick wetting, swelling and long
dispersion stage. On the opposite, the dispersion stage of the second
behaviour (high salt concentration) was significantly shortened
indicating a strong modification of the protein backbone. A salt
increase result to a destabilization of the micelle and the formation of
mini-micelles more or less aggregated indicating an average micelles
size ranging from 100 to 200 nm. For the first time, the estimations
of secondary structural elements (irregular, ß-sheet, α-helix and turn)
by the Amide III assignments were correlated with results from
Amide I.
Abstract: In this study, we have defined slant helix according to
Bishop frame in Euclidean 3-Space. Furthermore, we have given
some necassary and sufficient conditons for the slant helix.
Abstract: High strength concrete (HSC) provides high strength
but lower ductility than normal strength concrete. This low ductility
limits the benefit of using HSC in building safe structures. On the
other hand, when designing reinforced concrete beams, designers
have to limit the amount of tensile reinforcement to prevent the
brittle failure of concrete. Therefore the full potential of the use of
steel reinforcement can not be achieved. This paper presents the idea
of confining concrete in the compression zone so that the HSC will
be in a state of triaxial compression, which leads to improvements in
strength and ductility. Five beams made of HSC were cast and tested.
The cross section of the beams was 200×300 mm, with a length of 4
m and a clear span of 3.6 m subjected to four-point loading, with
emphasis placed on the midspan deflection. The first beam served as
a reference beam. The remaining beams had different tensile
reinforcement and the confinement shapes were changed to gauge
their effectiveness in improving the strength and ductility of the
beams. The compressive strength of the concrete was 85 MPa and the
tensile strength of the steel was 500 MPa and for the stirrups and
helixes was 250 MPa. Results of testing the five beams proved that
placing helixes with different diameters as a variable parameter in the
compression zone of reinforced concrete beams improve their
strength and ductility.
Abstract: The curves, of which the square of the distance
between the two points equal to zero, are called minimal or isotropic
curves [4]. In this work, first, necessary and sufficient conditions to
be a Pseudo Helix, which is a special case of such curves, are
presented. Thereafter, it is proven that an isotropic curve-s position
vector and pseudo curvature satisfy a vector differential equation of
fourth order. Additionally, In view of solution of mentioned
equation, position vector of pseudo helices is obtained.
Abstract: This paper aims at presenting the biotechnology used
to obtain collagen-based gels from shark (Squalus acanthias) and brill
skin, marine fish growing in the Black Sea. Due to the structure of its
micro-fibres, collagen can be considered a nanomaterial; in order to
use collagen-based matrixes as biomaterial, rheological studies must
be performed first, to state whether they are stable or not. For the
triple-helix structure to remain stable within these gels at room or
human body temperature, they must be stabilized by reticulation.