Abstract: In the paper, the relative performances on spectral
classification of short exon and intron sequences of the human and
eleven model organisms is studied. In the simulations, all
combinations of sixteen one-sequence numerical representations, four
threshold values, and four window lengths are considered. Sequences
of 150-base length are chosen and for each organism, a total of
16,000 sequences are used for training and testing. Results indicate
that an appropriate combination of one-sequence numerical
representation, threshold value, and window length is essential for
arriving at top spectral classification results. For fixed-length
sequences, the precisions on exon and intron classification obtained
for different organisms are not the same because of their genomic
differences. In general, precision increases as sequence length
increases.
Abstract: Attempts were made to identify anuran glial cells. They were found as nervous tissue resident. Having stage dependent morphotype changes, whereby, appeared as an ovoid to oval in resting state and amoeboid mrophotypes in activated state, stained fairly with methylene blue and take up Pelikane blue 10% aqueous solution, as well as having the ability to phagocytize heat killed Staphylococcus aureus. They were delineated from the migrating peripheral monocytes by morphotypic and morphometeric differences. Such criteria were consistence with glial cells. Thus, the anuran glial cells are being identified in the frog Rana ridibunda Pallas 1771 and this animal can be of use as a simple model for the immunobiology of glial cells.
Abstract: The changes in quality properties and nutritional
components in two fermented mugworts (Artemisia capillaries
Thumberg, Artemisiaeasiaticae Nakai) were characterized followed
by the rapid pattern analysis of volatile flavor compounds by Electric
Nose based on SAW(Surface Acoustic Wave) sensor in GC system.
There were remarkable decreases in the pH and small changes in the
total soluble solids after fermentation. The L (lightness) and b
(yellowness) values in Hunter's color system were shown to be
decreased, whilst the a (redness) value was increased by fermentation.
The HPLC analysis demonstrated that total amino acids were
increased in quantity and the essential amino acids were contained
higher in A. asiaticaeNakai than in A. capillaries Thumberg. While
the total polyphenol contents were not affected by fermentation, the
total sugar contents were dramatically decreased. Scopoletinwere
highly abundant in A. capillarisThumberg, however, it was not
detected in A. asiaticaeNakai. Volatile flavor compounds by Electric
Nose showed that the intensity of several peaks were increased much
and seven additional flavor peaks were newly produced after
fermentation. The flavor differences of two mugworts were clearly
distinguished from the image patterns of VaporPrintTM which indicate
that the fermentation enables the two mugworts to have subtle flavor
differences.
Abstract: Concerns about low levels of children-s physical activity and motor skill development, prompted the Ministry of Education to trial a physical activity pilot project (PAPP) in 16 New Zealand primary schools. The project comprised professional development and training in physical education for lead teachers and introduced four physical activity coordinators to liaise with and increase physical activity opportunities in the pilot schools. A survey of generalist teachers (128 baseline, 155 post-intervention) from these schools looked at timetabled physical activity sessions and issues related to teaching physical education. The authors calculated means and standard deviations of data relating to timetabled PE sessions and used a one-way analysis of variance to determine significant differences. Results indicated time devoted to physical activity related subjects significantly increased over the course of the intervention. Teacher-s reported improved confidence and competence, which resulted in an improvement in quality physical education delivered more often.
Abstract: Subjective loneliness describes people who feel a
disagreeable or unacceptable lack of meaningful social relationships,
both at the quantitative and qualitative level. The studies to be
presented tested an Italian 18-items self-report loneliness measure,
that included items adapted from scales previously developed,
namely a short version of the UCLA (Russell, Peplau and Cutrona,
1980), and the 11-items Loneliness scale by De Jong-Gierveld &
Kamphuis (JGLS; 1985). The studies aimed at testing the developed
scale and at verifying whether loneliness is better conceptualized as a
unidimensional (so-called 'general loneliness') or a bidimensional
construct, namely comprising the distinct facets of social and
emotional loneliness. The loneliness questionnaire included 2 singleitem
criterion measures of sad mood, and social contact, and asked
participants to supply information on a number of socio-demographic
variables. Factorial analyses of responses obtained in two
preliminary studies, with 59 and 143 Italian participants respectively,
showed good factor loadings and subscale reliability and confirmed
that perceived loneliness has clearly two components, a social and an
emotional one, the latter measured by two subscales, a 7-item
'general' loneliness subscale derived from UCLA, and a 6–item
'emotional' scale included in the JGLS. Results further showed that
type and amount of loneliness are related, negatively, to frequency of
social contacts, and, positively, to sad mood. In a third study data
were obtained from a nation-wide sample of 9.097 Italian subjects,
12 to about 70 year-olds, who filled the test on-line, on the Italian
web site of a large-audience magazine, Focus. The results again
confirmed the reliability of the component subscales, namely social,
emotional, and 'general' loneliness, and showed that they were
highly correlated with each other, especially the latter two.
Loneliness scores were significantly predicted by sex, age, education
level, sad mood and social contact, and, less so, by other variables –
e.g., geographical area and profession. The scale validity was
confirmed by the results of a fourth study, with elderly men and
women (N 105) living at home or in residential care units. The three
subscales were significantly related, among others, to depression, and
to various measures of the extension of, and satisfaction with, social
contacts with relatives and friends. Finally, a fifth study with 315
career-starters showed that social and emotional loneliness correlate
with life satisfaction, and with measures of emotional intelligence.
Altogether the results showed a good validity and reliability in the
tested samples of the entire scale, and of its components.
Abstract: the article analyzes the development prospects of
education system in Kazakhstan. Education is among key sources of
culture and social mobility. Modern education must become civic
which means availability of high quality education to all people
irrespective of their racial, ethnic, religious, social, gender and any
other differences. Socially focused nature of modernization of
Kazakhstan-s society is predicated upon formation of a civic
education model in the future. Kazakhstan-s education system
undergoes intensive reforms first of all intended to achieve
international education standards and integration into the global
educational and information space.
Abstract: Purpose of this work is to develop an automatic classification system that could be useful for radiologists in the breast cancer investigation. The software has been designed in the framework of the MAGIC-5 collaboration. In an automatic classification system the suspicious regions with high probability to include a lesion are extracted from the image as regions of interest (ROIs). Each ROI is characterized by some features based generally on morphological lesion differences. A study in the space features representation is made and some classifiers are tested to distinguish the pathological regions from the healthy ones. The results provided in terms of sensitivity and specificity will be presented through the ROC (Receiver Operating Characteristic) curves. In particular the best performances are obtained with the Neural Networks in comparison with the K-Nearest Neighbours and the Support Vector Machine: The Radial Basis Function supply the best results with 0.89 ± 0.01 of area under ROC curve but similar results are obtained with the Probabilistic Neural Network and a Multi Layer Perceptron.
Abstract: This paper dissertates about issues which may occur
after next year will be major part of civil aviation in EU included into
system of Emission trading. This system should help to fight against
global warming and to fulfill Kyoto Protocol commitments of
European countries. Main issues mentioned in this paper are
connected with problem of radiative forcing from emissions and lack
of their monitoring and charging in EU legislative. There are
mentioned main differences between industrial emissions and
emissions form aviation with notification about possible negative
impacts of neglecting these differences. Special attention is dedicated
to risk of possible reverse effect of inclusion aviation in EU ETS,
which may theoretically occur.
Abstract: The purpose of this study is to identify ideal urban
design elements of waterfronts and to analyze the differences in users-
cognition among these elements. This study follows three steps as
following: first is identifying the urban design elements of waterfronts
from literature review and second is evaluating intended users-
cognition of urban design elements in urban waterfronts. Lastly, third
is analyzing the users- cognition differences. As the result, evaluations
of waterfront areas by users show similar features that non-waterfront
urban design elements contain the highest degree of importance. This
indicates the difference of users- cognition has dimensions of
frequency and distance, and demonstrates differences in the aspect of
importance than of satisfaction. Multi-Dimensional Scaling Method
verifies differences among their cognition. This study provides
elements to increase satisfaction of users from differences of their
cognition on design elements for waterfronts. It also suggests
implications on elements when waterfronts are built.
Abstract: Bone remodeling occurs by the balanced action of
bone resorbing osteoclasts (OC) and bone-building osteoblasts.
Increased bone resorption by excessive OC activity contributes
to malignant and non-malignant diseases including osteoporosis.
To study OC differentiation and function, OC formed in
in vitro cultures are currently counted manually, a tedious
procedure which is prone to inter-observer differences. Aiming
for an automated OC-quantification system, classification of
OC and precursor cells was done on fluorescence microscope
images based on the distinct appearance of fluorescent nuclei.
Following ellipse fitting to nuclei, a combination of eight
features enabled clustering of OC and precursor cell nuclei.
After evaluating different machine-learning techniques, LOGREG
achieved 74% correctly classified OC and precursor cell
nuclei, outperforming human experts (best expert: 55%). In
combination with the automated detection of total cell areas,
this system allows to measure various cell parameters and most
importantly to quantify proteins involved in osteoclastogenesis.