Abstract: In today-s economy plant engineering faces many
challenges. For instance the intensifying competition in this business
is leading to cost competition and needs for a shorter time-to-market.
To remain competitive companies need to make their businesses
more profitable by implementing improvement programs such as
standardization projects. But they have difficulties to tap their full
economic potential for various reasons. One of them is non-holistic
planning and implementation of standardization projects. This paper
describes a new conceptual framework - the layer-model. The model
combines and expands existing proven approaches in order to
improve design, implementation and management of standardization
projects. Based on a holistic approach it helps to systematically
analyze the effects of standardization projects on different business
layers and enables companies to better seize the opportunities offered
by standardization.
Abstract: Literature review revealed the importance of the
adoption of marketing Relationship for loyalty and retaining
profitable customer (Customer Relationship Management). LPQ
satisfaction will reinforce the loyalty and customer brand
attachment. Customer will communicate the operator to others. The
focus of this study is to examine the relationship between the
LPPQ and the WOM recommendations through: customer
satisfaction, loyalty and attachment. The results show that LPQ
affect positively the satisfaction, negatively the loyalty. LPQ has an
indirectly effect on WOM recommendations but through the
satisfaction and attachment. The mediating effect of satisfaction in
the relationship between LPQ and Loyalty is rejected. This finding
can be explained by the nature of mobile sector in Tunisia.
Abstract: Unmanned aerial vehicles (UAVs) performing their
operations for a long time have been attracting much attention in
military and civil aviation industries for the past decade. The
applicable field of UAV is changing from the military purpose only to
the civil one. Because of their low operation cost, high reliability and
the necessity of various application areas, numerous development
programs have been initiated around the world. To obtain the optimal
solutions of the design variable (i.e., sectional airfoil profile, wing
taper ratio and sweep) for high performance of UAVs, both the lift and
lift-to-drag ratio are maximized whereas the pitching moment should
be minimized, simultaneously. It is found that the lift force and
lift-to-drag ratio are linearly dependent and a unique and dominant
solution are existed. However, a trade-off phenomenon is observed
between the lift-to-drag ratio and pitching moment. As the result of
optimization, sixty-five (65) non-dominated Pareto individuals at the
cutting edge of design spaces that are decided by airfoil shapes can be
obtained.
Abstract: We developed a multi-camera control system that a (one) cameraman can operate several cameras at a compact studio. we analyzed a workflow of a cameraman of some program shootings with two cameras and clarified their heavy tasks. The system based on a dynamic workflow which adapts a program progressing and recommends of cameraman. we perform the automation of multicamera controls by modeling of studio environment and perform automatic camera adjustment for suitable angle of view with face detection. Our experiment at a real program shooting showed that one cameraman can carry out the task of shooting sufficiently.
Abstract: Reachability graph (RG) generation suffers from the
problem of exponential space and time complexity. To alleviate the
more critical problem of time complexity, this paper presents the new
approach for RG generation for the Petri net (PN) models of parallel
processes. Independent RGs for each parallel process in the PN
structure are generated in parallel and cross-product of these RGs
turns into the exhaustive state space from which the RG of given
parallel system is determined. The complexity analysis of the
presented algorithm illuminates significant decrease in the time
complexity cost of RG generation. The proposed technique is
applicable to parallel programs having multiple threads with the
synchronization problem.
Abstract: When considering the development of constitutive
equations describing the behavior of materials under cyclic plastic
strains, different kinds of formulations can be adopted. The primary
intention of this study is to develop computer programming of
plasticity models to accurately predict the life of engineering
components. For this purpose, the energy or cyclic strain is computed
in multi-surface plasticity models in non-proportional loading and to
present their procedures and codes results.
Abstract: With the popularity of the multi-core and many-core architectures there is a great requirement for software frameworks which can support parallel programming methodologies. In this paper we introduce an Eclipse toolkit, JConqurr which is easy to use and provides robust support for flexible parallel progrmaming. JConqurr is a multi-core and many-core programming toolkit for Java which is capable of providing support for common parallel programming patterns which include task, data, divide and conquer and pipeline parallelism. The toolkit uses an annotation and a directive mechanism to convert the sequential code into parallel code. In addition to that we have proposed a novel mechanism to achieve the parallelism using graphical processing units (GPU). Experiments with common parallelizable algorithms have shown that our toolkit can be easily and efficiently used to convert sequential code to parallel code and significant performance gains can be achieved.
Abstract: The problem of lot sizing, sequencing and scheduling
multiple products in flow line production systems has been studied
by several authors. Almost all of the researches in this area assumed
that setup times and costs are sequence –independent even though
sequence dependent setups are common in practice. In this paper we
present a new mixed integer non linear program (MINLP) and a
heuristic method to solve the problem in sequence dependent case.
Furthermore, a genetic algorithm has been developed which applies
this constructive heuristic to generate initial population. These two
proposed solution methods are compared on randomly generated
problems. Computational results show a clear superiority of our
proposed GA for majority of the test problems.
Abstract: Chikungunya virus (CHICKV) is an arboviruses belonging to family Tagoviridae and is transmitted to human through by mosquito (Aedes aegypti and Aedes albopictus) bite. A large outbreak of chikungunya has been reported in India between 2006 and 2007, along with several other countries from South-East Asia and for the first time in Europe. It was for the first time that the CHICKV outbreak has been reported with mortality from Reunion Island and increased mortality from Asian countries. CHICKV affects all age groups, and currently there are no specific drugs or vaccine to cure the disease. The need of antiviral agents for the treatment of CHICKV infection and the success of virtual screening against many therapeutically valuable targets led us to carry out the structure based drug design against Chikungunya nSP2 protease (PDB: 3TRK). Highthroughput virtual screening of publicly available databases, ZINC12 and BindingDB, has been carried out using the Openeye tools and Schrodinger LLC software packages. Openeye Filter program has been used to filter the database and the filtered outputs were docked using HTVS protocol implemented in GLIDE package of Schrodinger LLC. The top HITS were further used for enriching the similar molecules from the database through vROCS; a shape based screening protocol implemented in Openeye. The approach adopted has provided different scaffolds as HITS against CHICKV protease. Three scaffolds: Indole, Pyrazole and Sulphone derivatives were selected based on the docking score and synthetic feasibility. Derivatives of Pyrazole were synthesized and submitted for antiviral screening against CHICKV.
Abstract: Application of neural networks in execution of
programmed pulse width modulation (PPWM) of a voltage source
inverter (VSI) is studied in this paper. Using the proposed method it is
possible to cancel out the desired harmonics in output of VSI in
addition to control the magnitude of fundamental harmonic,
contineously. By checking the non-trained values and a performance
index, the most appropriate neural network is proposed. It is shown
that neural networks may solve the custom difficulties of practical
utilization of PPWM such as large size of memory, complex digital
circuits and controlling the magnitude of output voltage in a discrete
manner.
Abstract: One of the most important problems in production planning of flexible manufacturing system (FMS) is machine tool selection and operation allocation problem that directly influences the production costs and times .In this paper minimizing machining cost, set-up cost and material handling cost as a multi-objective problem in flexible manufacturing systems environment are considered. We present a 0-1 integer linear programming model for the multiobjective machine tool selection and operation allocation problem and due to the large scale nature of the problem, solving the problem to obtain optimal solution in a reasonable time is infeasible, Paretoant colony optimization (P-ACO) approach for solving the multiobjective problem in reasonable time is developed. Experimental results indicate effectiveness of the proposed algorithm for solving the problem.
Abstract: Vitamin A deficiency is a public health problem in
Zimbabwe. Addressing vitamin A deficiency has the potential of
enhancing resistance to disease and reducing mortality especially in
children less than 5 years. We implemented and adapted vitamin A
outreach supplementation strategy within the National Immunization
Days and Extended Programme of Immunization in a rural district in
Zimbabwe. Despite usual operational challenges faced this approach
enabled the district to increase delivery of supplementation coverage.
This paper describes the outreach strategy that was implemented in
the remote rural district. The strategy covered 63 outreach sites with
2 sites being covered per day and visited once per month for the
whole year. Coverage reached 71% in an area of previous coverage
rates of around less than 50%. We recommend further exploration of
this strategy by others working in similar circumstances. This
strategy can be a potential way for use by Scaling-Up-Nutrition
member states.
Abstract: This work addresses the problem of optimizing
completely batch water-using network with multiple contaminants
where the flow change caused by mass transfer is taken into
consideration for the first time. A mathematical technique for
optimizing water-using network is proposed based on
source-tank-sink superstructure. The task is to obtain the freshwater
usage, recycle assignments among water-using units, wastewater
discharge and a steady water-using network configuration by
following steps. Firstly, operating sequences of water-using units are
determined by time constraints. Next, superstructure is simplified by
eliminating the reuse and recycle from water-using units with
maximum concentration of key contaminants. Then, the non-linear
programming model is solved by GAMS (General Algebra Model
System) for minimum freshwater usage, maximum water recycle and
minimum wastewater discharge. Finally, numbers of operating periods
are calculated to acquire the steady network configuration. A case
study is solved to illustrate the applicability of the proposed approach.
Abstract: The gas safety management system using an
intelligent gas meter we proposed is to monitor flow and
pressure of gas, earthquake, temperature, smoke and leak of
methane. Then our system takes safety measures to protect a
serious risk by the result of an event, to communicate with a
wall-pad including a gateway by zigbee network in buildings
and to report the event to user by the safety management
program in a server. Also, the inner cutoff valve of an
intelligent gas meter is operated if any event occurred or
abnormal at each sensor.
Abstract: This paper presents a new strategy of identification
and classification of pathological voices using the hybrid method
based on wavelet transform and neural networks. After speech
acquisition from a patient, the speech signal is analysed in order to
extract the acoustic parameters such as the pitch, the formants, Jitter,
and shimmer. Obtained results will be compared to those normal and
standard values thanks to a programmable database. Sounds are
collected from normal people and patients, and then classified into
two different categories. Speech data base is consists of several
pathological and normal voices collected from the national hospital
“Rabta-Tunis". Speech processing algorithm is conducted in a
supervised mode for discrimination of normal and pathology voices
and then for classification between neural and vocal pathologies
(Parkinson, Alzheimer, laryngeal, dyslexia...). Several simulation
results will be presented in function of the disease and will be
compared with the clinical diagnosis in order to have an objective
evaluation of the developed tool.
Abstract: Segmentation, filtering out of measurement errors and
identification of breakpoints are integral parts of any analysis of
microarray data for the detection of copy number variation (CNV).
Existing algorithms designed for these tasks have had some successes
in the past, but they tend to be O(N2) in either computation time or
memory requirement, or both, and the rapid advance of microarray
resolution has practically rendered such algorithms useless. Here we
propose an algorithm, SAD, that is much faster and much less thirsty
for memory – O(N) in both computation time and memory requirement
-- and offers higher accuracy. The two key ingredients of SAD are the
fundamental assumption in statistics that measurement errors are
normally distributed and the mathematical relation that the product of
two Gaussians is another Gaussian (function). We have produced a
computer program for analyzing CNV based on SAD. In addition to
being fast and small it offers two important features: quantitative
statistics for predictions and, with only two user-decided parameters,
ease of use. Its speed shows little dependence on genomic profile.
Running on an average modern computer, it completes CNV analyses
for a 262 thousand-probe array in ~1 second and a 1.8 million-probe
array in 9 seconds
Abstract: Food control measures are critical in fostering food safety management of a nation. However, no academic study has been undertaken to assess the food control system of Myanmar up to now. The objective of this research paper was to assess the food control system with in depth examination of five key components using desktop analysis and short survey from related food safety program organizations including regulators and inspectors. Study showed that the existing food control system is conventional, mainly focusing on primary health care approach while relying on reactive measures. The achievements of food control work have been limited to a certain extent due to insufficienttechnical capacity that is needed to upgrade staffs, laboratory equipment and technical assistance etc. associated with various sectors. Assessing food control measures is the first step in the integration of food safety management, this paper could assist policy makers in providing information for enhancing the safety and quality of food produced and consumed in Myanmar.
Abstract: A simple and easy algorithm is presented for a fast calculation of kernel functions which required in fluid simulations using the Smoothed Particle Hydrodynamic (SPH) method. Present proposed algorithm improves the Linked-list algorithm and adopts the Pair-Wise Interaction technique, which are widely used for evaluating kernel functions in fluid simulations using the SPH method. The algorithm is easy to be implemented without any complexities in programming. Some benchmark examples are used to show the simulation time saved by using the proposed algorithm. Parametric studies on the number of divisions for sub-domains, smoothing length and total amount of particles are conducted to show the effectiveness of the present technique. A compact formulation is proposed for practical usage.
Abstract: This paper proposes a bi-objective model for the
facility location problem under a congestion system. The idea of the
model is motivated by applications of locating servers in bank
automated teller machines (ATMS), communication networks, and so
on. This model can be specifically considered for situations in which
fixed service facilities are congested by stochastic demand within
queueing framework. We formulate this model with two perspectives
simultaneously: (i) customers and (ii) service provider. The
objectives of the model are to minimize (i) the total expected
travelling and waiting time and (ii) the average facility idle-time.
This model represents a mixed-integer nonlinear programming
problem which belongs to the class of NP-hard problems. In addition,
to solve the model, two metaheuristic algorithms including nondominated
sorting genetic algorithms (NSGA-II) and non-dominated
ranking genetic algorithms (NRGA) are proposed. Besides, to
evaluate the performance of the two algorithms some numerical
examples are produced and analyzed with some metrics to determine
which algorithm works better.
Abstract: MiRNAs participate in gene regulation of translation.
Some studies have investigated the interactions between genes and
intragenic miRNAs. It is important to study the miRNA binding sites
of genes involved in carcinogenesis. RNAHybrid 2.1 and ERNAhybrid
programmes were used to compute the hybridization free
energy of miRNA binding sites. Of these 54 mRNAs, 22.6%, 37.7%,
and 39.7% of miRNA binding sites were present in the 5'UTRs,
CDSs, and 3'UTRs, respectively. The density of the binding sites for
miRNAs in the 5'UTR ranged from 1.6 to 43.2 times and from 1.8 to
8.0 times greater than in the CDS and 3'UTR, respectively. Three
types of miRNA interactions with mRNAs have been revealed: 5'-
dominant canonical, 3'-compensatory, and complementary binding
sites. MiRNAs regulate gene expression, and information on the
interactions between miRNAs and mRNAs could be useful in
molecular medicine. We recommend that newly described sites
undergo validation by experimental investigation.