Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: The manufacturing technology of band cotton is very
delicate and depends to choice of certain parameters such as torsion
of warp yarn.
The fabric elasticity is achieved without the use of any elastic
material, chemical expansion, artificial or synthetic and it’s capable
of creating pressures useful for therapeutic treatments.
Before use, the band is subjected to treatments of specific
preparation for obtaining certain elasticity, however, during its
treatment, there are some regression parameters. The dependence of
manufacturing parameters on the quality of the chemical treatment
was confirmed.
The aim of this work is to improve the properties of the fabric
through the development of manufacturing technology appropriately.
Finally for the treatment of the strip pancake 100% cotton, a
treatment method is recommended.
Abstract: This article presents summary on preparation and
characterization of zinc, copper, cadmium and cobalt chromite
nanocrystals, embedded in an amorphous silica matrix. The
ZnCr2O4/SiO2, CuCr2O4/SiO2, CdCr2O4/SiO2 and CoCr2O4/SiO2
nanocomposites were prepared by a conventional sol-gel method
under acid catalysis. Final heat treatment of the samples was carried
out at temperatures in the range of 900−1200 ◦C to adjust the
phase composition and the crystallite size, respectively. The resulting
samples were characterized by Powder X-ray diffraction (PXRD),
High Resolution Transmission Electron Microscopy (HRTEM),
Raman/FTIR spectroscopy and magnetic measurements. Formation
of the spinel phase was confirmed in all samples. The average size of
the nanocrystals was determined from the PXRD data and by direct
particle size observation on HRTEM; both results were correlated.
The mean particle size (reviewed by HRTEM) was in the range from
∼4 to 46 nm. The results showed that the sol-gel method can be
effectively used for preparation of the spinel chromite nanoparticles
embedded in the silica matrix and the particle size is driven by the
type of the cation A2+ in the spinel structure and the temperature
of the final heat treatment. Magnetic properties of the nanocrystals
were found to be just moderately modified in comparison to the bulk
phases.
Abstract: The organizations of European and Czech critical
infrastructure have specific position, mission, characteristics and
behaviour in European Union and Czech state/business environments,
regarding specific requirements for regional and global security
environments. They must respect policy of national security and
global rules, requirements and standards in all their inherent and
outer processes of supply - customer chains and networks. A
controlling is generalized capability to have control over situational
policy. This paper aims and purposes are to introduce the controlling
as quite new necessary process attribute providing for critical
infrastructure is environment the capability and profit to achieve its
commitment regarding to the effectiveness of the quality
management system in meeting customer/ user requirements and also
the continual improvement of critical infrastructure organization’s
processes overall performance and efficiency, as well as its societal
security via continual planning improvement via DYVELOP
modelling.
Abstract: The fundamental issues in ICT Governance (ICTG)
implementation for Malaysian Public Sector (MPS) is how ICT be
applied to support improvements in productivity, management
effectiveness and the quality of services offered to its citizens. Our
main concern is to develop and adopt a common definition and
framework to illustrate how ICTG can be used to better align ICT
with government’s operations and strategic focus. In particular, we
want to identify and categorize factors that drive a successful ICTG
process. This paper presents the results of an exploratory study to
identify, validate and refine such Critical Success Factors (CSFs) and
confirmed seven CSFs and nineteen sub-factors as influential factors
that fit MPS after further validated and refined. The Delphi method
applied in validation and refining process before being endorsed as
appropriate for MPS. The identified CSFs reflect the focus areas that
need to be considered strategically to strengthen ICT Governance
implementation and ensure business success.
Abstract: Load Forecasting plays a key role in making today's
and future's Smart Energy Grids sustainable and reliable. Accurate
power consumption prediction allows utilities to organize in advance
their resources or to execute Demand Response strategies more
effectively, which enables several features such as higher
sustainability, better quality of service, and affordable electricity
tariffs. It is easy yet effective to apply Load Forecasting at larger
geographic scale, i.e. Smart Micro Grids, wherein the lower available
grid flexibility makes accurate prediction more critical in Demand
Response applications. This paper analyses the application of
short-term load forecasting in a concrete scenario, proposed within the
EU-funded GreenCom project, which collect load data from single
loads and households belonging to a Smart Micro Grid. Three
short-term load forecasting techniques, i.e. linear regression, artificial
neural networks, and radial basis function network, are considered,
compared, and evaluated through absolute forecast errors and training
time. The influence of weather conditions in Load Forecasting is also
evaluated. A new definition of Gain is introduced in this paper, which
innovatively serves as an indicator of short-term prediction
capabilities of time spam consistency. Two models, 24- and
1-hour-ahead forecasting, are built to comprehensively compare these
three techniques.
Abstract: Metal-enhanced Luminescence of silicon nanocrystals
(SiNCs) was determined using two different particle sizes of silver
nanoparticles (AgNPs). SiNCs have been characterized by scanning
electron microscopy (SEM), high resolution transmission electron
microscopy (HRTEM), Fourier transform infrared spectroscopy
(FTIR) and X-ray photoelectron spectroscopy (XPS). It is found that
the SiNCs are crystalline with an average diameter of 65 nm and FCC
lattice. AgNPs were synthesized using photochemical reduction of
AgNO3 with sodium dodecyl sulphate (SDS). The enhanced
luminescence of SiNCs by AgNPs was evaluated by confocal Raman
microspectroscopy. Enhancement up to x9 and x3 times were
observed for SiNCs that mixed with AgNPs which have an average
particle size of 100 nm and 30 nm, respectively. Silver NPs-enhanced
luminescence of SiNCs occurs as a result of the coupling between the
excitation laser light and the plasmon bands of AgNPs; thus this
intense field at AgNPs surface couples strongly to SiNCs.
Abstract: Artemisia species, which are medically beneficial, are
widespread in temperate regions of both Northern and Southern
hemispheres among which Iran is located. About 35 species of
Artemisia are indigenous in Iran among them some are widespread in
all or most provinces, yet some are restricted to some specific
regions. In this review paper, initially, GC-Mass results of some
experiments done in different provinces of Iran are mentioned among
them some compounds are common among species, some others are
mostly restricted to other species; after that, medical advantages
based on some researches on species of this genus are reviewed;
different qualities such as anti-leishmania, anti-bacteria, antiviral as
well as anti-proliferative could be mentioned.
Abstract: Class cohesion is a key object-oriented software
quality attribute that is used to evaluate the degree of relatedness of
class attributes and methods. Researchers have proposed several class
cohesion measures. However, the effect of considering the special
methods (i.e., constructors, destructors, and access and delegation
methods) in cohesion calculation is not thoroughly theoretically
studied for most of them. In this paper, we address this issue for three
popular connectivity-based class cohesion measures. For each of the
considered measures we theoretically study the impact of including
or excluding special methods on the values that are obtained by
applying the measure. This study is based on analyzing the
definitions and formulas that are proposed for the measures. The
results show that including/excluding special methods has a
considerable effect on the obtained cohesion values and that this
effect varies from one measure to another. For each of the three
connectivity-based measures, the proposed theoretical study
recommended excluding the special methods in cohesion
measurement.
Abstract: Nonalcoholic fatty liver disease (NAFLD) has
increased in conjunction with obesity. The accuracy of risk factors
for detecting NAFLD in obese adolescents has not undergone a
formal evaluation. The aim of this study was to evaluate predictors of
NAFLD among Egyptian female obese adolescents. The study
included 162 obese female adolescents. All were subjected to
anthropometry, biochemical analysis and abdominal ultrasongraphic
assessment. Metabolic syndrome (MS) was diagnosed according to
the IDF criteria. Significant association between presence of MS and
NAFLD was observed. Obese adolescents with NAFLD had
significantly higher levels of ALT, triglycerides, fasting glucose,
insulin, blood pressure and HOMA-IR, whereas decreased HDL-C
levels as compared with obese cases without NAFLD. Receiver–
operating characteristic (ROC) curve analysis shows that ALT is a
sensitive predictor for NAFLD, confirming that ALT can be used as a
marker of NAFLD.
Abstract: Due to reduced stiffness, research on second
generation titanium alloys for implant applications, like the
metastable β-titanium alloy Ti-15Mo, become more and more
important in the recent years. The machinability of these alloys is
generally poor leading to problems during implant production and
comparably large production costs. Therefore, in the present study,
Ti-15Mo was alloyed with 0.8 wt.-% of the rare earth metals
lanthanum (Ti-15Mo+0.8La) and neodymium (Ti-15Mo+0.8Nd) to
improve its machinability. Their microstructure consisted of a
titanium matrix and micrometer-size particles of the rare earth metals
and two of their oxides. The particles stabilized the microstructure as
grain growth was minimized. As especially the ductility might be
affected by the precipitates, the behavior of Ti-15Mo+0.8La and Ti-
15Mo+0.8Nd was investigated during static and dynamic
deformation at elevated temperature to develop a processing route.
The resulting mechanical properties (static strength and ductility)
were similar in all investigated alloys.
Abstract: The mathematical analysis on radiation obtained and
the development of the solar photovoltaic (PV) array groundwater
pumping is needed in the rural areas of Thohoyandou for sizing and
power performance subject to the climate conditions within the area.
A simple methodology approach is developed for the directed
coupled solar, controller and submersible ground water pump system.
The system consists of a PV array, pump controller and submerged
pump, battery backup and charger controller. For this reason, the
theoretical solar radiation is obtained for optimal predictions and
system performance in order to achieve different design and
operating parameters. Here the examination of the PV schematic
module in a Direct Current (DC) application is used for obtainable
maximum solar power energy for water pumping. In this paper, a
simple efficient photovoltaic water pumping system is presented with
its theoretical studies and mathematical modeling of photovoltaics
(PV) system.
Abstract: This paper is about method to produce a stable and
accurate constant output pulse width regardless of the amplitude,
period and pulse width variation of the input signal source. The pulse
generated is usually being used in numerous applications as the
reference input source to other circuits in the system. Therefore, it is
crucial to produce a clean and constant pulse width to make sure the
system is working accurately as expected.
Abstract: Calcium phosphate coating (CaP) has been employed
for protein delivery, but the typical direct protein adsorption on the
coating led to low incorporation content and fast release of the
protein from the coating. By using bovine serum albumin (BSA) as a
model protein, rapid biomimetic co-precipitation between calcium
phosphate and BSA was employed to control the distribution of BSA
within calcium phosphate coating during biomimetic formation on
titanium surface for only 6 h at 50oC in an accelerated calcium
phosphate solution. As a result, the amount of BSA incorporation and
release duration could be increased by using a rapid biomimetic coprecipitation
technique. Up to 43 fold increases in the BSA
incorporation content and the increase from 6 h to more than 360 h in
release duration compared to typical direct adsorption technique were
observed depending on the initial BSA concentration used during coprecipitation
(1, 10 and 100 μg.ml-1). From x-ray diffraction and
Fourier transform infrared spectroscopy studies, the coating
composition was not altered with the incorporation of BSA by this
rapid biomimetic co-precipitation and mainly comprised octacalcium
phosphate and hydroxyapatite. However, the microstructure of
calcium phosphate crystals changed from straight, plate-like units to
curved, plate-like units with increasing BSA content.
Abstract: The article presents the concept of an electromagnetic
circuit generator with permanent magnets mounted on the surface
rotor core designed for single phase work. Computation field-circuit
model was shown. The spectrum of time course of voltages in the
idle work was presented. The cross section with graphically
presentation of magnetic induction in particular parts of
electromagnetic circuits was presented. Distribution of magnetic
induction at the rated load point for each phase was shown. The time
course of voltages and currents for each phases for rated power were
displayed. An analysis of laboratory results and measurement of load
characteristics of the generator was discussed. The work deals with
three electromagnetic circuits of generators with permanent magnet
where output voltage characteristics versus rated power were
expressed.
Abstract: To mimic the natural circumstances of cell growth in an organism, we present three-dimensional (3D) scaffolds fabricated by microfluidics for cultivation. This work investigates the cellular behaviors of rat cardiomyocytes in gelatin 3D scaffolds compared to those on 2D control, such as proliferation, viability and morphology. We found that the scaffolds may induce skeletal differentiation of H9c2 cells.
Abstract: The success of any retail business is predisposed by its
swift response and its knack in understanding the constraints and the
requirements of customers. In this paper a conceptual design model
of an automated customer-friendly supermarket has been proposed.
In this model a 10-sided, space benefited, regular polygon shaped
gravity shelves have been designed for goods storage and effective
customer-specific algorithms have been built-in for quick automatic
delivery of the randomly listed goods. The algorithm is developed
with two main objectives, viz., delivery time and priority. For
meeting these objectives the randomly listed items are reorganized
according to the critical-path of the robotic arm specific to the
identified shop and its layout and the items are categorized according
to the demand, shape, size, similarity and nature of the product for an
efficient pick-up, packing and delivery process. We conjectured that
the proposed automated supermarket model reduces business
operating costs with much customer satisfaction warranting a winwin
situation.
Abstract: Mass flow measurement is the basis of most technoeconomic
formulations in the chemical industry. This calls for
reliable and accurate detection of mass flow. Flow measurement
laboratory experiments were conducted using various instruments.
These consisted of orifice plates, various sized rotameters, wet gas
meter and soap bubble meter. This work was aimed at evaluating
appropriate operating conditions and accuracy of the aforementioned
devices. The experimental data collected were compared to
theoretical predictions from Bernoulli’s equation and calibration
curves supplied by the instrument’s manufacturers. The results
obtained showed that rotameters were more reliable for measuring
high and low flow rates; while soap-bubble meters and wet-gas
meters were found to be suitable for measuring low flow rates. The
laboratory procedures and findings of the actual work can assist
engineering students and professionals in conducting their flow
measurement laboratory test work.
Abstract: An anthropometric study applied to 1,115 students of
the Faculty of Chemical Sciences and Engineering of the
Autonomous University of California. Thirteen individual
measurements were taken in a sitting position. The results obtained
allow forming a reliable anthropometric database for statistical
studies and analysis and inferences of specific distributions, so the
opinion of experts in occupational medicine recommendations may
emit to reduce risks resulting in an alteration of the vital signs during
the execution of their school activities. Another use of these analyses
is to use them as a reliable reference for future deeper research, to the
design of spaces, tools, utensils, workstations, with anthropometric
dimensions and ergonomic characteristics suitable to use.
Abstract: This paper presents an anthropometric study
conducted to 300 employees in a maquiladora industry that belongs
to the cluster of medical products as part of a research project to
pretend simulate workplace conditions under which operators
conduct their activities. This project is relevant because traditionally
performed a study to design ergonomic workspaces according to
anthropometric profile of users, however, this paper demonstrates the
importance of making decisions when the infrastructure cannot be
adapted for economic whichever put emphasis on user activity.