The Biomechanical Properties of the Different Modalities of Surgically Corrected Coarctation of the Aorta in Neonates and Infants
Biomechanical properties of infantile aorta in vitro in
cases of different standard anastomoses: end-to-end (ETE), extended
anastomosis end-to-end (EETE) and subclavian flap aortoplasty
(SFA) used for surgical correction of coarctation were analyzed to
detect the influence of the method on the biomechanics of infantile
aorta and possible changes in haemodinamics. 10 specimens of native
aorta, 3 specimens with ETE, 4 EEET and 3 SFA were investigated.
The experiments showed a non-linear relationship between stress and
strain in the infantile aorta, the modulus of elasticity of the aortic wall
increased with the increase of inner pressure. In the case of
anastomosis end-to-end the modulus was almost constant, relevant to
the modulus of elasticity of the aorta with the inner pressure 100-120
mmHg. The anastomoses EETE and SFA showed elastic properties
closer to native aorta, the stiffness of ETE did not change with the
changes in inner pressure.
[1] G. J. I. E. Hofman and S. Kaplan, "The incidence of congenital heart
disease," J Am Coll Cardiol, vol .39, pp. 1890-1900, 2002.
[2] A. Lindinger, G. Schwedler and H.W. Hense, "Results of PAN Study:
Congenital heart defects in newborns in Germany-prevalence and
association with demographic, genetic and peripartal parameters,"
Cardiol Young, vol. 20 (SuppS2), pp. S3, 2010.
[3] "European surveillance of congenital anomalies," www.eurocatnetwork.
eu/prevdata/results (accessed 10.03.2012.).
[4] S. Fruh, W. Knorsh, A. Dodge-Khatami, H. Dave, R. Petre and O.
Kretschmar, "Comparison of surgical and interventional therapy of
native and recurrent aortic coarctation regarding different age groups
during childhood," Eur J Cardiothorac Surg, vol. 39, pp. 989-904, 2011.
[5] A. Peres, J. D. Martins, F. Parames, R. Gil, C. Matias, J. Franco, I.
Freitas , C. TrigoC, J. Fragata and F. F. Pinto, " Isolated coarctation :
experience in 100 consecutive patients," Rev Port Cardiol, vol. 29(1),
pp. 23-35, 2010.
[6] R. J. Walhout, J. C. Lekkerkerker, G.H. Oron, G.B. Bennink and E. J.
Meijboom, "Compariso of surgical repair with balloon angioplasty for
native coarctation in patients from 3 months to 16 years of age ," Eur J
Cardiothorac Surg, vol. 25, pp. 722-727, 2004.
[7] R. H. Beekman, " Coarctation of the aorta , Moss and Adams, Heart
Disease in Infants, Children and Adolescents Including the Fetus and
Toung Adult," Hugh Allen, Lippincott Williams& Wilkins, Seventh
edition, vol. 49, pp. 987-1005, 2008.
[8] E. Rosenthal, "Coarctation of the aorta from fetus to adult: curable
condition or life long disease process?" Heart; vol. 91(11), pp.1495-
1502, 2005.
[9] R.A. Jonas, "Coarctation of the aorta, Comprehensive Surgical
management of Congenital Heart Disease," Hodder Arnold Publication,
pp. 207-223, 2004.
[10] A. E. Wood, H. Javadpour, D. Duff, P. Oslizlok and K. Walsh, " Is
extended arch aortoplasty the operation of choice for infant aortic
coarctation? Results of 15 years` experience in 181 patients," Ann
Thorac Surg, vol. 77, pp. 1353-1358, 2004.
[11] J. D. R. Thomson, A. Mulpur, R. Guerrero, Z. Nagy, J. L. Gibbs and K.
G. Watterson, "Outcome after extended arch repair for aortic
coarctation," Heart, vol. 92, pp. 90-94, 2006.
[12] C. J. Barreiro, T. A. Ellison, J. A. Williams, M. L. Durr, D. E. Cameron
and L. A. Vricella, "Subclavian flap aortoplasty: still a safe,
reproducible and effective treatment for infant coarctation," Eur J
Cardiothorac Surg, vol. 31(4). pp. 649-53, 2007.
[13] A. Cobanoglu, K. Ganeeshakrishnan, K. Thyagarajan and J. L. Dobbs,
"Surgery for coarctation of the aorta in infants younger than 3 months:
end-to-end repair versus subclavian flap angioplasty: is either operation
better?" Eur J Cardiothorac Surg, vol.14, pp. 19-26, 1998.
[14] B. Korbmacher, O. N. Krogmann, S. Rammos, E. Godehardt, T. Volk,
D. Schulte and E. Gams, "Repair of critical aortic coarctation in
neonatal age," J Cardiovasc Surg, vol. 43, pp. 1-6, 2002.
[15] J. W. Brown, M. Ruzmetov, M. H. Hoyer, M. D. Rodefeld and M. W.
Turrentine, "Recurrent Coarctation: Is Surgical Repair of Recurrent
Coarctation Safe anf Effective?" Ann Thorac Surg, vol. 88, pp. 1923-
1932, 2009.
[16] F. Burch, C. G. Cowley, R. Holubkov, D. Null, L. Lambert , P. C.
Kouretas and J. A. Hawkins, " Coarctation repair in neonates and young
infants: is small size or low weight arrisk factor?" J Thorac Cardiovasc
Surg, vol. 138, pp. 547-552, 2009.
[17] P. P. Bassereo, A. R. Marras, M. E. Manai and G. Mercuro, "The
influence of different surgical approaches on arterial rigidity in children
after aortic coarctation repair," Pediatr cardiol, vol. 30(4), pp. 414-418,
2009.
[18] U. Giordano, S. Giannico, A. Turchetta, F. Hammand, F. Calzolari and
A. Calzolari, "The influence of different surgical procedures on
hypertension after repair of coarctation," Cardiol Young, vol. 15, pp.
477-480, 2005.
[19] P. Guerin, M. Jimenez, M. Vallot, J. B. Thambo and P. Goose, " Arterial
rigidity of patients operated successfully for coarctationof the aorta
without residual hypertension," Arch Mal Coeur Vaiss, vol. 98, pp. 557-
560, 2005.
[20] P. Ou, D. Celermajer, O. Jolivet, F. Buyens, A. Herment, D. Sidi, D.
Bonne and E. Mousseaux ,"Increased central aortic stiffness and left
ventricle mass in normotensive young subjects after successfull
coarctation repair," Am Heart J, vol. 155(1), pp. 187-193, 2008.
[21] P. Ou, D. Bonnet and L. Auriacombe, "Late systemic hypertension and
aortic arch geometry after succesfull reapir of coarctation of the aorta,"
Eur Heart J , vol. 25, pp. 1853-1859, 2004.
[22] E. Ligere, A. Lacis, L. Smits, V. Ozolins, N. Sikora, I. Bergmane, I.
Lubaua , I. Lace and L. Feldmane,"Aortic coarctation repaired within
the first year of life: an 11 year review," Acta Chirurgica Latviensis, vol.
11/2, pp. 98-103, 2011.
[23] K. M. Park and G. Troxler, "Pediatric Cardiology for Practitioners,"
Mosby, 4th Edition, pp. 105-590, 2008.
[1] G. J. I. E. Hofman and S. Kaplan, "The incidence of congenital heart
disease," J Am Coll Cardiol, vol .39, pp. 1890-1900, 2002.
[2] A. Lindinger, G. Schwedler and H.W. Hense, "Results of PAN Study:
Congenital heart defects in newborns in Germany-prevalence and
association with demographic, genetic and peripartal parameters,"
Cardiol Young, vol. 20 (SuppS2), pp. S3, 2010.
[3] "European surveillance of congenital anomalies," www.eurocatnetwork.
eu/prevdata/results (accessed 10.03.2012.).
[4] S. Fruh, W. Knorsh, A. Dodge-Khatami, H. Dave, R. Petre and O.
Kretschmar, "Comparison of surgical and interventional therapy of
native and recurrent aortic coarctation regarding different age groups
during childhood," Eur J Cardiothorac Surg, vol. 39, pp. 989-904, 2011.
[5] A. Peres, J. D. Martins, F. Parames, R. Gil, C. Matias, J. Franco, I.
Freitas , C. TrigoC, J. Fragata and F. F. Pinto, " Isolated coarctation :
experience in 100 consecutive patients," Rev Port Cardiol, vol. 29(1),
pp. 23-35, 2010.
[6] R. J. Walhout, J. C. Lekkerkerker, G.H. Oron, G.B. Bennink and E. J.
Meijboom, "Compariso of surgical repair with balloon angioplasty for
native coarctation in patients from 3 months to 16 years of age ," Eur J
Cardiothorac Surg, vol. 25, pp. 722-727, 2004.
[7] R. H. Beekman, " Coarctation of the aorta , Moss and Adams, Heart
Disease in Infants, Children and Adolescents Including the Fetus and
Toung Adult," Hugh Allen, Lippincott Williams& Wilkins, Seventh
edition, vol. 49, pp. 987-1005, 2008.
[8] E. Rosenthal, "Coarctation of the aorta from fetus to adult: curable
condition or life long disease process?" Heart; vol. 91(11), pp.1495-
1502, 2005.
[9] R.A. Jonas, "Coarctation of the aorta, Comprehensive Surgical
management of Congenital Heart Disease," Hodder Arnold Publication,
pp. 207-223, 2004.
[10] A. E. Wood, H. Javadpour, D. Duff, P. Oslizlok and K. Walsh, " Is
extended arch aortoplasty the operation of choice for infant aortic
coarctation? Results of 15 years` experience in 181 patients," Ann
Thorac Surg, vol. 77, pp. 1353-1358, 2004.
[11] J. D. R. Thomson, A. Mulpur, R. Guerrero, Z. Nagy, J. L. Gibbs and K.
G. Watterson, "Outcome after extended arch repair for aortic
coarctation," Heart, vol. 92, pp. 90-94, 2006.
[12] C. J. Barreiro, T. A. Ellison, J. A. Williams, M. L. Durr, D. E. Cameron
and L. A. Vricella, "Subclavian flap aortoplasty: still a safe,
reproducible and effective treatment for infant coarctation," Eur J
Cardiothorac Surg, vol. 31(4). pp. 649-53, 2007.
[13] A. Cobanoglu, K. Ganeeshakrishnan, K. Thyagarajan and J. L. Dobbs,
"Surgery for coarctation of the aorta in infants younger than 3 months:
end-to-end repair versus subclavian flap angioplasty: is either operation
better?" Eur J Cardiothorac Surg, vol.14, pp. 19-26, 1998.
[14] B. Korbmacher, O. N. Krogmann, S. Rammos, E. Godehardt, T. Volk,
D. Schulte and E. Gams, "Repair of critical aortic coarctation in
neonatal age," J Cardiovasc Surg, vol. 43, pp. 1-6, 2002.
[15] J. W. Brown, M. Ruzmetov, M. H. Hoyer, M. D. Rodefeld and M. W.
Turrentine, "Recurrent Coarctation: Is Surgical Repair of Recurrent
Coarctation Safe anf Effective?" Ann Thorac Surg, vol. 88, pp. 1923-
1932, 2009.
[16] F. Burch, C. G. Cowley, R. Holubkov, D. Null, L. Lambert , P. C.
Kouretas and J. A. Hawkins, " Coarctation repair in neonates and young
infants: is small size or low weight arrisk factor?" J Thorac Cardiovasc
Surg, vol. 138, pp. 547-552, 2009.
[17] P. P. Bassereo, A. R. Marras, M. E. Manai and G. Mercuro, "The
influence of different surgical approaches on arterial rigidity in children
after aortic coarctation repair," Pediatr cardiol, vol. 30(4), pp. 414-418,
2009.
[18] U. Giordano, S. Giannico, A. Turchetta, F. Hammand, F. Calzolari and
A. Calzolari, "The influence of different surgical procedures on
hypertension after repair of coarctation," Cardiol Young, vol. 15, pp.
477-480, 2005.
[19] P. Guerin, M. Jimenez, M. Vallot, J. B. Thambo and P. Goose, " Arterial
rigidity of patients operated successfully for coarctationof the aorta
without residual hypertension," Arch Mal Coeur Vaiss, vol. 98, pp. 557-
560, 2005.
[20] P. Ou, D. Celermajer, O. Jolivet, F. Buyens, A. Herment, D. Sidi, D.
Bonne and E. Mousseaux ,"Increased central aortic stiffness and left
ventricle mass in normotensive young subjects after successfull
coarctation repair," Am Heart J, vol. 155(1), pp. 187-193, 2008.
[21] P. Ou, D. Bonnet and L. Auriacombe, "Late systemic hypertension and
aortic arch geometry after succesfull reapir of coarctation of the aorta,"
Eur Heart J , vol. 25, pp. 1853-1859, 2004.
[22] E. Ligere, A. Lacis, L. Smits, V. Ozolins, N. Sikora, I. Bergmane, I.
Lubaua , I. Lace and L. Feldmane,"Aortic coarctation repaired within
the first year of life: an 11 year review," Acta Chirurgica Latviensis, vol.
11/2, pp. 98-103, 2011.
[23] K. M. Park and G. Troxler, "Pediatric Cardiology for Practitioners,"
Mosby, 4th Edition, pp. 105-590, 2008.
@article{"International Journal of Medical, Medicine and Health Sciences:62252", author = "Elina Ligere and Valts Ozolins and Lauris Smits and Normunds Sikora and Ivars Melderis and Laila Feldmane and Aris
Lacis and Vladimir Kasyanov", title = "The Biomechanical Properties of the Different Modalities of Surgically Corrected Coarctation of the Aorta in Neonates and Infants", abstract = "Biomechanical properties of infantile aorta in vitro in
cases of different standard anastomoses: end-to-end (ETE), extended
anastomosis end-to-end (EETE) and subclavian flap aortoplasty
(SFA) used for surgical correction of coarctation were analyzed to
detect the influence of the method on the biomechanics of infantile
aorta and possible changes in haemodinamics. 10 specimens of native
aorta, 3 specimens with ETE, 4 EEET and 3 SFA were investigated.
The experiments showed a non-linear relationship between stress and
strain in the infantile aorta, the modulus of elasticity of the aortic wall
increased with the increase of inner pressure. In the case of
anastomosis end-to-end the modulus was almost constant, relevant to
the modulus of elasticity of the aorta with the inner pressure 100-120
mmHg. The anastomoses EETE and SFA showed elastic properties
closer to native aorta, the stiffness of ETE did not change with the
changes in inner pressure.", keywords = "biomechanics, coarctation, mechanical properties,
neonatal aorta", volume = "6", number = "6", pages = "262-4", }