Sericin Film: Influence of Concentration on its Physical Properties
Silk sericin (SS) is a glue-like protein from silkworm
cocoon. With its outstanding moisturization and activation collagen
synthesis properties, silk protein is applied for wound healing. Since
wound dressing in film preparation can facilitate patients-
convenience and reduce risk of wound contraction, SS and polyvinyl
alcohol (PVA) films were prepared with various concentrations of
SS. Their physical properties such as surface density, light
transmission, protein dissolution and tensile modulus were
investigated. The results presented that 3% SS with 2% PVA is the
best ingredient for SS film forming.
[1] M. N. Padamwar, and A. P. Pawar, "Silk sericin and its applications: A
review," Journal of Scientific & Industrial Research., Vol. 63, pp 323-
329, April 2004.
[2] Y. Takasu, H. Yamada, and K. Tsubouchi,, "Isolation of Three Main
Sericin Components from the Cocoon of the Silkworm, Bombyx mori."
Biosci. Biotechnol. Biochem., 66(12), 2715-2718, 2002.
[3] S. Tokutake, "Isolation of the Smallest Component of Silk Protein."
Biochem. J., 187, 413-417, 1980.
[4] T. K. Hunt, "Disorder of Wound Healing," World J. Surg., 4, 271-
7,1980.
[5] P. Aramwit, et al. "The effect of Sericin with Variable Amino-Acid
Content from Different Silk Strains on the Production of Collagen and
Nitric Oxide," Journal of Biomaterials Science, Vol. 20(9), pp. 1295-
1306(12), 2009.
[6] K. Tsubouchi, Y. Igarashi, Y. Takasu, "Sericin Enhances Attachment of
cultured Human Shin Fibroblasts," Biosci. Biotechnol. Biochem., 69(2),
403-05, 2005.
[7] N. Nagai, et al. "Enhancing Effects of Sericin on Corneal Wound
Healing in Rat Debrided Corneal Epithelium," Biol. Pharm. Bull. 32(5),
933-936, 2009.
[8] P. Aramwit, A. Sangcakul, "The effects of Sericin Cream on Wound
Healing in Rats." Biosci. Biotechnol. Biochem.,71(10), 2473-2477,
2007.
[9] P. Aramwit, et al., "Monitoring of inflammatory mediators induced by
silk sericin," Journal of bioscience and bioengineering, 107(5), 556-61,
2009
[10] S. F. Swaim, S. H. Hinkle, D. M. Bradley., "Wound Contraction : Basic
and Clinical Factors," Compendium, 23(1), 20-34, 2001
[11] P. Muangman, J. Jantarasakul, Early Burn Wound Care. Update on
Wound Care, Thailand, 81-110, 2009.
[12] G. O. Liza, "Advances in wound dressings," Clinics in Dermatology, 25,
33-38, 2007.
[13] J. Vanessa, E. G. Joseph, and G. H. Keith, "Wound Dressings," BMJ.
Vol. 332, 777-780, 2006.
[14] T.D. Turner, "Hospital Usage of Absorbent Dressings," Pharmaceutical
J., Vol. 222: 421-424, 1979.
[15] J. Perez-Riguerio, C. Viney, J. Llorca, and M. Elices, "Mechanical
properties of single-brin silkworm silk." Journal of Applied Polymer
Science. 75(10), 1270-7, 2000.
[16] X. Zhang, et al. "Poly(vinyl alcohol)/SWNT Composite Film.," Nano
Lett., 3(9), 1285-8, 2003.
[1] M. N. Padamwar, and A. P. Pawar, "Silk sericin and its applications: A
review," Journal of Scientific & Industrial Research., Vol. 63, pp 323-
329, April 2004.
[2] Y. Takasu, H. Yamada, and K. Tsubouchi,, "Isolation of Three Main
Sericin Components from the Cocoon of the Silkworm, Bombyx mori."
Biosci. Biotechnol. Biochem., 66(12), 2715-2718, 2002.
[3] S. Tokutake, "Isolation of the Smallest Component of Silk Protein."
Biochem. J., 187, 413-417, 1980.
[4] T. K. Hunt, "Disorder of Wound Healing," World J. Surg., 4, 271-
7,1980.
[5] P. Aramwit, et al. "The effect of Sericin with Variable Amino-Acid
Content from Different Silk Strains on the Production of Collagen and
Nitric Oxide," Journal of Biomaterials Science, Vol. 20(9), pp. 1295-
1306(12), 2009.
[6] K. Tsubouchi, Y. Igarashi, Y. Takasu, "Sericin Enhances Attachment of
cultured Human Shin Fibroblasts," Biosci. Biotechnol. Biochem., 69(2),
403-05, 2005.
[7] N. Nagai, et al. "Enhancing Effects of Sericin on Corneal Wound
Healing in Rat Debrided Corneal Epithelium," Biol. Pharm. Bull. 32(5),
933-936, 2009.
[8] P. Aramwit, A. Sangcakul, "The effects of Sericin Cream on Wound
Healing in Rats." Biosci. Biotechnol. Biochem.,71(10), 2473-2477,
2007.
[9] P. Aramwit, et al., "Monitoring of inflammatory mediators induced by
silk sericin," Journal of bioscience and bioengineering, 107(5), 556-61,
2009
[10] S. F. Swaim, S. H. Hinkle, D. M. Bradley., "Wound Contraction : Basic
and Clinical Factors," Compendium, 23(1), 20-34, 2001
[11] P. Muangman, J. Jantarasakul, Early Burn Wound Care. Update on
Wound Care, Thailand, 81-110, 2009.
[12] G. O. Liza, "Advances in wound dressings," Clinics in Dermatology, 25,
33-38, 2007.
[13] J. Vanessa, E. G. Joseph, and G. H. Keith, "Wound Dressings," BMJ.
Vol. 332, 777-780, 2006.
[14] T.D. Turner, "Hospital Usage of Absorbent Dressings," Pharmaceutical
J., Vol. 222: 421-424, 1979.
[15] J. Perez-Riguerio, C. Viney, J. Llorca, and M. Elices, "Mechanical
properties of single-brin silkworm silk." Journal of Applied Polymer
Science. 75(10), 1270-7, 2000.
[16] X. Zhang, et al. "Poly(vinyl alcohol)/SWNT Composite Film.," Nano
Lett., 3(9), 1285-8, 2003.
@article{"International Journal of Medical, Medicine and Health Sciences:57155", author = "N. Namviriyachote and N. Bang and P. Aramwit", title = "Sericin Film: Influence of Concentration on its Physical Properties", abstract = "Silk sericin (SS) is a glue-like protein from silkworm
cocoon. With its outstanding moisturization and activation collagen
synthesis properties, silk protein is applied for wound healing. Since
wound dressing in film preparation can facilitate patients-
convenience and reduce risk of wound contraction, SS and polyvinyl
alcohol (PVA) films were prepared with various concentrations of
SS. Their physical properties such as surface density, light
transmission, protein dissolution and tensile modulus were
investigated. The results presented that 3% SS with 2% PVA is the
best ingredient for SS film forming.", keywords = "Sericin, silk protein, film, wound healing.", volume = "3", number = "8", pages = "209-3", }
